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Prospects for Pharmaceuticals: Selling our Strengths Abroad Jon Mowles, UKTI Sector Specialist Japan Society 9th Nov ‘11 Setting the scene The UK is ranked as the best performer in the G8 leading economies per unit of R&D spend. 4 of the top 6 rated universities in the world are in the UK viz. Cambridge, University College London, Imperial College and Oxford. 5 of the top 20 medicines in terms of global sales were developed in the UK. In the last 10 years Life Sciences departments within UK universities have generated over 200 spin-out companies, now employing over 1,000 people. Benefits: The United Kingdom is a global centre of excellence in Life Sciences where: – – – – Innovation is readily commercialised. People are highly skilled and motivated. Government is supportive and businesses prosper. High value given to R&D. 2 Pharmaceutical: Global FDI - 2006 - 10 Destination City No of Projects 2006-2010 Singapore 39 8% Shanghai 26 65 6% Beijing 14 UK 61 6% Budapest 13 Germany 59 5.5% Prague 11 Ireland 46 4% Mumbai 10 Singapore 39 3.5% France 38 3.5% Tokyo 10 Russia 35 3% Dublin 10 Canada 30 2.8% Sao Paulo 9 Berlin 9 Hyderabad 9 Moscow 9 Destination Country No of Projects 2006-2010 % of global FDI USA 119 11% China 85 India Time Series: January 2006- December 2010 3 Source: fDi Markets™ Pharmaceutical: UK FDI 2006 - 10 - On average the UK is recipient of 12 Pharmaceutical projects per annum. - Motives for UK investment in sector both skilled workforce and proximity to market were cited as primary drivers. - R&D accounted for 39% of Pharmaceutical investment followed by manufacturing and sales, support & marketing. - UK hubs of investment were identified in London, Cambridge and Scotland. Attractiveness / Quality of Life Universities or researchers Technology or Innovation Industry Cluster / Critical Mass Facilities Site or Real Estate Domestic Market Growth Potential IPA or Govt support Infrastructure and logistics • Skilled workforce availability Proximity to markets or customers 0% 5% 10% 15% 20% TOP UK INVESTORS (2006 – 2010): Quintiles; Pfizer; Nicholas Piramal India (NPIL); Amgen; Icon; Warner Chilcott; Kendle International; Eisai; Intercell; Novartis; Granules India; Patheon; Clariant; Wyeth; Merck KGaA; Glenmark Pharmaceuticals; Teva Pharmaceutical Industries; UCB Group; Sanofi-Aventis; Evotec OAI; Bilcare 4 Biopharma: Global FDI - 2006 - 10 Destination Country No of Projects 2006-2010 % of global FDI USA 79 16% UK 59 China Destination Cities No of Projects 20062010 13% Singapore 23 38 8% Shanghai 16 India 33 7% London 12 Germany 29 6% Boston (MA) 8 Singapore 23 5% Dubai 7 France 16 3.5% Beijing 6 Belgium 13 3% Bangalore 6 Netherlands 12 3% Dublin 6 Ireland 12 3% Tokyo 6 Cambridge 6 Time Series: January 2006- December 2010 5 Source: fDi Markets™ Biopharma: UK FDI 2006 - 10 - On average the UK is recipient of 12 Biotechnology projects per annum. - Motives for UK investment in sector – 26% surveyed cited Government support as key driver. - R&D accounted for 41% of Biotechnology investment in the UK 2006-2010. Sales, marketing and support accounted for 30%. - UK hubs of investment were identified in London, Cambridge and Scotland. Infrastructure and logistics Industry Cluster / Critical Mass Finance Incentives or Taxes or Funding Facilities Site or Real Estate Domestic Market Growth Potential Technology or Innovation • Skilled workforce availability Universities or researchers Proximity to markets or customers IPA or Govt support 0% 5% 10% 15% 20% 25% 30% TOP UK INVESTORS (2006 – 2010): Life Technologies (Invitrogen); SigmaAldrich; Millipore; Genzyme; Pfizer; Magellan Biosciences; Bioanalytical Systems (BASi); Bristol-Myers Squibb; ScheringPlough; Wyeth; Serologicals; Waters; Eurofins Scientific; Cognia; BioMarin Pharmaceutical; MatriCal; Fziomed; IdentiGEN; BioGuard Components & Technologies; MediciNova 6 UK BioPharma Networks Scotland (Edinburgh, Dundee, Aberdeen) • Human and animal healthcare • Environmental biotechnology • Gene therapy • Protein engineering • Combinatorial chemistry North (Manchester, York, Liverpool, Newcastle) • Bio-health informatics • Genomics and Proteomics • Medical Imaging • Clinical Genetics • Bio-manufacturing • Agricultural/Food Sciences Cambridge • Biopharmaceuticals • Drug discovery-genomics, • proteomics • bioinformatics • combinatorial chemistry • Protein/DNA sequencing/engineering • Biomaterials Northern Ireland • Diagnostics • Agriculture • Veterinary medicine • Food Sciences • Environmental Oxford • Proteomics • Genomics • Chemical libraries • Vaccines • Monoclonal antibodies Wales • Diagnostics •Healthcare • Biotechnology Surrey • Agricultural biotechnology • Production of reagents: cell/tissue cultures London • Biopharmaceuticals • Decoding/transformation of DNA material • Functions of sub-cellular organisms • Functional genomics (Source: UKTI Sector Group, 2007) 7 UKTI: Conclusions 1. Within the Life Sciences Sector, the UK is a good place to do business 2. UK Trade & Investment is the UK Government organisation that: Helps overseas companies to bring high quality investment to the UK economy. Helps UK-based companies access international markets to succeed in an increasingly global economy. Works with existing foreign investors to grow their business in the UK and internationally. A global network. UKTI has staff in British Embassies, High Commissions and other diplomatic offices around the world. UK Trade & Investment – Winner 2010: Best Trade Promotion Organisation in the developed world UKTI LOOKS TO ADD VALUE! 8 Jon Mowles Life Sciences Sector Specialist Investment Directorate - London UK Trade & Investment [email protected] Tel: +44 (0) 7826 912 923 UKTI Website: www.uktradeinvest.gov.uk 9