VT EATS: VERMONT EFFECTIVE ADOLESCENT TREATMENT …

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Transcript VT EATS: VERMONT EFFECTIVE ADOLESCENT TREATMENT …

The Global Appraisal of Individual Needs
(GAIN) Evaluator’s Handbook:
Practical Guidelines for Using GAIN Data To
Support Local and Cross-Site Program
Evaluation and Development
Michael Dennis, Melissa Ives, & Rodney Funk
Chestnut Health Systems, Bloomington, IL
Joint Meeting on Adolescent Treatment Effectiveness,
April 25-27, 2007, Washington, DC
Objectives
1.
Identify common questions used in evaluations
and available GAIN tools and reports.
2.
Understand how to respond to these questions
using GAIN data, tools and reports.
3.
Identify and answer questions that will help you
use GAIN to support program evaluation and
development.
4.
Get your input on what would be most useful to
have in the GAIN Evaluators Handbook
Questions
1.
We will encourage you to ask questions as we go
if something is not clear
2.
We are handing out note cards to get more
detailed questions to answer at the end. If you
put your e-mail or address on them (or sign up)
we will send you copies of our answers in
writing.
3.
Are there anything you are specifically here for
that you want us to be sure and cover?
Common Questions in
Local Program Evaluation
and Clinical Research
1.
2.
3.
4.
5.
6.
Who is being served?
What services are they receiving?
To what extent are services being targeted at the
those in need?
To what extent are services being delivered as
expected? (Performance/Fidelity)
Which is most effective of several services
delivered?
What does it cost, cost effectiveness?
Source: Dennis, Fetterman & Sechrest (1994)
GAIN Scales & Variable File
1.
2.
3.
4.
5.
6.
7.
8.
Purpose
Type of Measure
Interpretative Cut Points
Description
Syntax
References
Items
Summarizing in a table
Purpose
1.
2.
3.
4.
5.
6.
7.
Diagnosis based on APA
Treatment planning based on CARF, COA,
JCAHO, NIDA principals and SAMHSA TIPs
Placement based on ASAM and statistical
models
Covariates based on lifetime or past year
measures
Change Scores based on past 90 days, month,
week or current status or time since last event
Methods Measures
Economic Measures
Types of Measures
1.
2.
3.
4.
5.
Scale: a set of “symptoms” or items that are intercorrelated (e.g.., dependence, depression) where
we are interested in the pattern (i.e. Common
variance, ONLY one where alpha makes sense)
Index: a set of items that may not be directly
related but add up to predict (e.g., sources of
stress, barriers to treatment, expenses)
Ratio Estimators: one measure divided by another
(e.g.., percent of unprotected sex acts)
Status measures: a categorical status based on a
single question or created across multiple (e.g..,
vocational status, housing status)
Survival: Time to first event (e.g. time to first use)
Interpretative Cut-Points
Definition of low, moderate and high clinical
significance bands to aid interpretation and
decision making (scale name + “g” for group)
2. Useful for defining need at both the client and
program level
3. Basis
- DSM or other clinical standards where
available (e.g.., clinical is 3+/7 dependence)
- 50th & 90th percentile for common issues (e.g.
days of alcohol use)
- 1+ and median of 1+ for zero saturated (more
than half) and right skewed variables
4. Reversed coded if “up” is low clinical significance
1.
Descriptions
GAIN-I S&V excel file has text based
descriptions, literal syntax (including older
version if applicable), items, and references
2. GAIN main scales and indexes word file includes
text to put in a journal article or report, including:
- short definition
- any subscales
- source of measure
- key reports/citations
- alphas for adolescents and adults if applicable
3. The articles in the GAIN bibliography (many of
which are included on the CD) have more details
as well.
1.
Possible Comparison Groups
•
•
•
•
•
•
•
•
•
published data
site over time
subsites, staff, or clinics
compare site to larger program (all sites)
compare site to similar level of care, geography,
demographic subgroup, or clinical subgroup
match clinical subgroups from GAIN related
presentations or papers
formal matching or propensity scoring to make
groups more statistically comparable
formal randomized experiments
path or mediation models to test whether it is
actually the dosage or key ingredient driving the
change
Major Predictors of Effective Programs
that we have to be cognizant of..
1.
An explicit intervention protocol (typically
manualized) that a priori evidence that it
works when followed
2.
Use of monitoring, feedback, supervision and
quality assurance to ensure protocol
adherence and project implementation
3.
Use proactive case supervision at the
individual level to ensure quality of care
4.
Triage to focus on the higher severity
subgroups of individuals
Impact of Intake Severity on Outcome
10
SPSM groupings
8
OVERALL
No problems (0-25%ile)
6
1-3 problems (25-50%ile)
4-8 problems (50-75%ile)
4
9+ problems (75-100%ile)
Dot/Lines show Means
2
0
0
6
Wave
Source: ATM Main Findings data set
Intake Severity
Correlated -.66 with
amount of change
Different than Regression to the Mean
10
SPSM groupings
8
OVERALL
No problems (0-25%ile)
6
1-3 problems (25-50%ile)
4-8 problems (50-75%ile)
4
9+ problems (75-100%ile)
Dot/Lines show Means
2
0
0
6
Wave
Source: ATM Main Findings data set
In its most basic form,
the mean & variance
are the same at both
time points; no
correlation between
intake & amount of
change
Different than Regression to the Mean
10
SPSM groupings
8
OVERALL
No problems (0-25%ile)
6
1-3 problems (25-50%ile)
4-8 problems (50-75%ile)
4
9+ problems (75-100%ile)
Dot/Lines show Means
2
0
0
6
Wave
Source: ATM Main Findings data set
If it was regression
around the mean
combined with an
mean effect it would;
but still no change in
variance or correlation
between intake &
amount of change
Example of Multi-dimensional
HIV Subgroups
0.01
0.00
0.00
0.20
Unprotected Sex Acts (f=.14)
-0.39
-0.29
-0.40
-0.60
-0.08
-0.20
-0.03
-0.10
-0.02
0.00
-0.04
Days of Victimization (f=.22)
Days of Needle Use (f=1.19)
-0.80
-0.69
Cohen's Effect Size d
0.15
0.10
0.20
0.27
0.40
A.
Low Risk
B.
C.
D.
Mod. Risk Low Mod. Risk High Very High Risk
W/T
W/T
Source: Lloyd et al 2007
Total
Key things to Test and Monitor

Assumptions about population characteristics and
needs (using site profiles)

Comparability of comparison groups (using site
profiles)

Simple performance measures and early outcomes
for monitoring implementation

Measure of competence, fidelity and
implementation

Variability in outcomes by subgroup
Melissa Ives

Melissa will now demonstrate how to use some of
the data and tools we provide to do these things.
GAIN Evaluator’s Handbook: Resources for
answering
'Who is being served?'
Melissa L. Ives, MSW
Research Associate
Chestnut Health Systems
Lighthouse Institute
GAIN Coordinating Center
Joint Meeting on Adolescent Treatment Effectiveness,
April 25-27, 2007, Washington, DC
Introduction and goals



The first of the 5 key questions is
– Who is being served?
Two goals of this portion of the presentation:
– Identify tools that are already available from the GCC.
– Explore the use of one key tool for examining
characteristics of those being served.
Always our goal: To answer your questions.
– Be sure to write down any questions that are not
answered during the presentation.
– Answers to these questions will be used to enhance the
Evaluator’s Handbook.
Overview

It is always easier to use the right tool than to create a new
one
– especially if the tool is readily available.

I used the AutoContent Wizard provided by PowerPoint to
create these slides.

The GCC currently provides several tools to support
evaluators or analysts in answering the key questions.
Tools
GAIN-I /
M90 data
Syntax &
template
files
Electronic
Site
Profiles
Evaluator
Or
Analyst
Encyclopedia
(GI S&V)
LI Analytic
Training
Series
Memos
TTL Report
FUL Report
Adult &
Adolesce
nt
Norms
Site Profiles



Excel file containing information about the characteristics
of clients being served.
Aggregated by site within a program or study.
Contents:
– Title page – defining what groups are included (with grant
numbers as acknowledgement) and what time period is covered.
– Chart Options – Interactive tab to select desired site(s)
–
–
–
–
–
included in graphs.
Table of Contents – list of graph
Single site charts
Two-group comparison charts
Data tables
Worksheets
Site Profiles

Provided quarterly for CSAT Programs on the
APSS website.

Can be created as <varname> Profiles (based on a
variable other than site).

A version for Level of Care is provided on today’s
CD.
Example from
ESD 113: Olympia, WA

EAT site with additional GAIN data from 2 other locations.

Interested in examining one of these locations in
comparison with the rest of their own EAT site and with
the whole EAT program.

Used the SPSS syntax and template in Excel
Open ESD Site Profiles
Open ESD Presentation
Summary



At this point you should:
– Be aware of the existence of several tools to assist you
in understanding who is being served.
– Be able to find information about tools you want to use.
– Be excited about how you can use these tools for your
own analysis.
– NOT be worried if you still have questions!
WRITE any questions on your index card.
For a direct reply after this meeting:
– Write legibly and include your name and e-mail
address.
Where to Get More Information
 Our website:
– http://www.chestnut.org/li/
 FTP Common Site: Evaluator’s Folder
– ftp://data.chestnut.org
 Username: Common
 Password:
public
 Send e-mail to:
– [email protected]
Information
about CHS
studies
LI Analytic
Presentations
Training
Series
and Posters
APSS
GAIN Information
Data Sharing
GAINAgreements
Instrument:
Archive
APSS
Norms, Naming Conventions, & GAIN-I Scales and Variables file!!
Where to Get More Information
 Our website:
– http://www.chestnut.org/li/
 FTP Common Site: Evaluator’s Folder
– ftp://data.chestnut.org
 Username: Common
 Password:
public
 Send e-mail to:
– [email protected]
Examples of Analysis Using
GAIN Data
Rod Funk
Chestnut Health Systems,
Bloomington, IL
Acknowledgement:
This presentation was developed under contract #270-2003-00006 from the
Center for Substance Abuse Treatment (CSAT) of the Substance Abuse and
Mental Health Services Administration (SAMHSA) and presents data from
the Persistent Effects of Treatment Study (PETS, Contract No. 270-97-7011)
and the Cannabis Youth Treatment (CYT) Cooperative Agreement (Grant
Nos. TI11317, TI11320, TI11321, TI11323, and TI11324) as well as the
Assertive Continuing Care Study supported by funds and data from the
National Institute on Alcoholism & Alcohol Abuse (RO1 AA 10368). The
opinions are those of the authors and do not reflect official positions of the
government.
Evaluating the Effects of Treatment
Treatment Outcome
Long Term Stability
Difference between intake and
Difference between average of short term
average of all short term
follow-ups (3-12) and long term follow-up (30)
follow-ups (3-12)
Month
0.00
Z-Score
-0.10
-0.20
-0.30
-0.40
-0.50
-0.60
Short Term Outcome Stability
Difference between average of
early (3-6) and latter (9-12)
follow-up interviews
Source: Dennis et al, 2003, 2004
Freq. of Use
Sub. Prob.
Change in Substance Frequency Scale in
Substance Frequency Index
CYT Experiment Incremental
1: Incremental
Arm
Arm
0.25
Treatment Outcome:
-Use reduced (-34%)
- No Sig. Dif. by condition
0.20
MET/CBT5
MET/CBT12
FSN
0.15
0.10
0.05
0.00
0
3
6
Short Term Stability:
- Outcomes stable (-1%)
- No Sig. Dif. by condition
Source: Dennis et al, CPDD, 2003
9
12
15
18
Months from Intake
21
24
27
30
Long Term Stability:
- Use increases (+64%)
- No Sig. Dif. by condition
Change in Substance Frequency Scale in
Substance Frequency Index
CYT Experiment Alternative
2: Alternative
Arm
Arm
0.25
0.20
Treatment Outcome:
- Use reduced (-35%)
- No Sig. Dif. by condition
MET/CBT5
ACRA
MDFT
0.15
0.10
0.05
0.00
0
3
6
9
Short Term Stability:
-Further reductions (-6%)
- Sig. Dif. by condition
(+4% vs. –10% vs. –11%)
Source: Dennis et al, CPDD 2003
12
15
18
Months from Intake
21
24
27
30
Long Term Stability:
- Outcomes stable (+20%)
-No Sig. Dif. by condition
Average Episode Cost ($US) of Treatment
Average Cost Per Client-Episode of Care
|--------------------------------------------Economic Cost-------------------------------------------|-------- Director Estimate-----|
$4,000
Less thanLess than
average average
for 6 weeks
for 12 weeks
$3,322
$3,500
$3,000
$3,495
$2,500
$1,984
$1,776
$2,000
$1,559
$1,500
$1,126
$1,197
$1,000
$500
$-
Source: French et al., 2002, 2003
$1,413
Recovery (CPPR)
Cost Per Person in
Cost Per Person in Recovery at 12 and 30
Months After Intake by CYT Condition
Stability of
Experiment 1 (n=299)
MET/CBT-5
findings
$30,000 MET/CBT-5, -12
mixed atand
30 months
ACRA more
Experiment 2 (n=297)
ACRA Effect
Largely Sustained
$25,000 cost effective at
$20,000
12 months
$15,000
$10,000
$5,000
$0
MET/ CBT5 MET/ CBT12
FSNM
MET/ CBT5
ACRA
MDFT
CPPR at 12 months**
$6,437
$10,405
$24,725
$27,109
$8,257
$14,222
CPPR at 30 months*
$3,958
$7,377
$15,116
$6,611
$4,460
$11,775
* P<.0001, Cohen’s f= 1.42 and 1.77 at 12 months
** P<.0001, Cohen’s f= 0.76 and 0.94 at 30 months
Source: Dennis et al., 2004; 2005
Integrated family therapy (MDFT)
was more cost effective than adding
it on top of treatment (FSN) at 30
months
Environmental Factors are also
the Major Predictors of Relapse
AOD use in the home, family
problems, homelessness, fighting,
victimization, self help group
participation, structure activities
Family
Conflict
-.54
.18
-.13
Family
Cohesion
-.09
Baseline
.32
.77
Recovery
Environment
Risk
.17
.22
.32
.82
.19
Social
Support
-.08
Peer AOD use, fighting,
illegal activity,
treatment, recovery,
vocational activity
The effects of adolescent
treatment are mediated by the
extent to which they lead to
actual changes in the recovery
environment or peer group
Social
Risk
.21
Baseline
.32
Substance
Use
.11
.19
Baseline
.58
.74
.43
SubstanceRelated
Problems
.22
Baseline
Model Fit
CFI=.97 to .99 by follow-up wave
RMSEA=.04 to .06 by wave
Source: Godley, Kahn et al (2005)
Assertive Continuing Care (ACC) Hypotheses
Assertive
Continuin
g Care
General
Continuin
g Care
Adherence
Early
Abstinence
Relative to UCC, ACC will increase General
Continuing Care Adherence (GCCA)
GCCA (whether due to UCC or ACC) will be
associated with higher rates of early abstinence
Early abstinence will be associated with higher
rates of long term abstinence.
Sustained
Abstinence
Weekly Tx
Weekly 12 step meetings
Relapse prevention*
Communication skills training*
Problem solving component*
Regular urine tests
Meet with parents 1-2x month*
Weekly telephone contact*
Contact w/probation/school
Referrals to other services*
Follow up on referrals*
Discuss probation/school compliance*
Adherence: Meets 7/12 criteria*
Source: Godley et al 2002, 2007
UCC
ACC
* p<.05
100%
90%
80%
70%
60%
50%
40%
30%
20%
10%
0%
ACC Improved General Continuing Care Adherence (GCCA)
ACC was associated with Reduced Relapse
Proportion Remaining Abstinent
from Marijuana
1.0
.9
ACC almost doubled
the time before relapse
and reduce long term
relapse
.8
.7
.6
.5
.4
ACC
.3
.2
UCC
.1
0.0
0
30
60
90
120 150
Days to First Marijuana Use
Source; Godley et al 2002
180
p<.05
210
240 270
GCCA Improved Early (0-3 mon.) Abstinence
100%
90%
Regardless of
condition
80%
70%
60%
55%
50%
43%
36%
40%
30%
55%
38%
24%
20%
10%
0%
Any AOD (OR=2.16*)
Low (0-6/12) GCCA
Source: Godley et al 2002, 2007
Alcohol (OR=1.94*)
High (7-12/12) GCCA
Marijuana (OR=1.98*)
* p<.05
Early (0-3 mon.) Abstinence Improved
Sustained (4-9 mon.) Abstinence
100%
90%
80%
73%
69%
70%
59%
60%
50%
40%
30%
20%
19%
22%
22%
10%
0%
Any AOD (OR=11.16*)
Alcohol (OR=5.47*)
Early(0-3 mon.) Relapse
Early (0-3 mon.) Abstainer
Source: Godley et al 2002, 2007
Marijuana (OR=11.15*)
* p<.05
Victimization and Level of Care Interact
to Predict Outcomes
Marijuana Use (Days of 90)
40
CHS Outpatient
CHS Residential
Traumatized groups
35have higher severity
30
25
20
15
10
High trauma group
does not respond to OP
5
0
Intake
OP -High
6 Months
OP - Low/Mod
Source: Funk, et al., 2003
Both groups respond to
residential treatment
Intake
Resid-High
6 Months
Resid - Low/Mod.
How do CHS OP’s high GVS outcomes compare with
other OP programs on average?
Z-Score on Substance Frequency Scale (SFS)
1.00
0.80
0.60
0.40
CYT Total (n=217; d=0.51)
Other programs
serve clients who
have significantly
higher severity
ATM Total (n=284; d=0.41)
CHSOP (n=57; d=0.18)
0.20
0.00
And on average they have
moderate effect sizes even
with high GVS
-0.20
-0.40
-0.60
-0.80
-1.00
Green line is CHS OP’s High GVS adolescents;
they have some initial gains but substantial relapse
Intake
Mon 1-3
Mon 4-6
Source: CYT and ATM Outpatient Data Set, Dennis 2005
Mon 7-9
Mon 10-12
Which 5 OP programs did the best with
high GVS adolescents?
The two best were
used with much
higher severity
adolescents and
TDC was not
manualized
Z-Score on Substance Frequency Scale (SFS)
1.00
0.80
0.60
7 Challenges (n=42; d=1.21)
Tucson Drug Court (n=27; d=0.65)
MET/CBT5a (n=34; d=0.62)
MET/CBT5b (n=40; d=0.55)
0.40
FSN/MET/CBT12 (n=34; d=0.53)
0.20
CHSOP (n=57; d=0.18)
0.00
-0.20
-0.40
-0.60
-0.80
-1.00
Next we can check to see if they are
any more similar in severity
Intake
Mon 1-3
Mon 4-6
Source: CYT and ATM Outpatient Data Set, Dennis 2005
Currently CHS is doing an
experiment comparing its
Mon
7-9 OP with
MonMET/CBT5
10-12
regular
Methodological Issues to Be Aware of..
• Site differences: Beware of demographic differences
between sites, such as on gender and race. You can use
cluster analysis to create homogeneous subgroups or
propensity scores to create more equivalent groups.
• Floor & Ceiling Effects: Check distributions of outcome
variables. If wanting to look at needle use, there is very
little to begin with in the CSAT data which would make it
difficult to look at change over time.
• Non-normal distributions: A lot of variables used for
outcome analysis can be very zero saturated and therefore
highly right skewed.
Methodological Issues Continued..
• Co-Occurring Disorders: Beware that
adolescents are more than likely presenting
for more problems than just substance use,
such as internal and external disorders.
• Controlled Environment: Be sure to check for days in
controlled environment. You may need to adjust your
outcomes, such as days of abstinence. You could subtract
days in a controlled environment from your dependent
variable, use it as another outcome variable or use it as a
covariate in your analysis
References
Dennis, M. (2005). State of the art of treating adolescent substance use disorders: Course, treatment
system, and evidence based practices. Paper presented at the 2005 State Adolescent Coordinators
(SAC) Grantee Orientation Meeting, Baltimore, MD. http://www.chestnut.org/LI/Posters
Dennis, M. L., Godley, S. H., Diamond, G., Tims, F. M., Babor, T., Donaldson, J., Liddle, H., et al. (2004).
The Cannabis Youth Treatment (CYT) study: Main findings from two randomized trials. Journal of
Substance Abuse Treatment, 27, 197–213.
Dennis, M. L., et al. (2003).Cannabis Youth Treatment Experiment: 12 and 30 Month Findings.
Presentation at College of problems of Drug Dependence, Bal Harbour, FL.
http://www.chestnut.org/LI/Posters
French, M.T., Roebuck, M.C., Dennis, M.L., Diamond, G., Godley, S.H., Tims, F., Webb, C., & Herrell,
J.M. (2002). The economic cost of outpatient marijuana treatment for adolescents: Findings from a
multisite experiment. Addiction, 97, S84-S97.
French, M. T., Roebuck, M. C., Dennis, M. L., Diamond, G., Godley, S. H., Liddle, H. A., and Tims, F. M.
(2003). Outpatient marijuana treatment for adolescents Economic evaluation of a multisite field
experiment. Evaluation Review,27(4)421-459.
Funk, R. R., McDermeit, M., Godley, S. H., & Adams, L. (2003). Maltreatment issues by level of
adolescent substance abuse treatment The extent of the problem at intake and relationship to early
outcomes. Journal of Child Maltreatment, 8, 36-45.
Godley, M. D., Godley, S. H., Dennis, M. L., Funk, R., & Passetti, L. (2002). Preliminary outcomes from
the assertive continuing care experiment for adolescents discharged from residential treatment.
Journal of Substance Abuse Treatment, 23, 21-32.
Godley, M. D., Godley, S. H., Dennis, M. L., Funk, R. R., & Passetti, L. L. (2007). The effect of Assertive
Continuing Care on continuing care linkage, adherence, and abstinence following residential
treatment for adolescents with substance use disorders. Addiction, 102, 81-93.
Godley, M. D., Kahn, J. H., Dennis, M. L., Godley, S. H., & Funk, R. R. (2005). The stability and impact
of environmental factors on substance use and problems after adolescent outpatient treatment.
Psychology of Addictive Behaviors, 19, 62-70.