Transcript Slide 1

Epilepsy

Dr. Hardeep Singh Malhotra MD, DM, FIACM, MNAMS

Associate Professor, Department of Neurology, King George’s Medical University, Lucknow

MCQ-1

• When do you label a “seizure” as “epilepsy”?

– Presence of family history – >1 unprovoked seizure – >1 provoked seizure – >2 provoked seizures

MCQ-1

• When do you label a “seizure” as “epilepsy”?

– Presence of family history – >1 unprovoked seizure – >1 provoked seizure – >2 provoked seizures

MCQ-2

• All of the following are excitatory neurotransmitters except: – AMPA – NMDA – GABA – Glutamate

MCQ-2

• All of the following are excitatory neurotransmitters except: – AMPA – NMDA – GABA – Glutamate

MCQ-3

• Which of the following abnormality is associated with ‘Generalized Epilepsy & Febrile Seizures plus’ syndrome?

– Sodium channel mutations – Calcium channel mutations – Potassium channel mutations – Chloride channel mutations

MCQ-3

• Which of the following abnormality is associated with ‘Generalized Epilepsy & Febrile Seizures plus’ syndrome?

– Sodium channel mutations – Calcium channel mutations – Potassium channel mutations – Chloride channel mutations

MCQ-4

• Which of the following abnormality is associated with ‘Juvenile Myoclonic Epilepsy’?

– Sodium channel mutations – Calcium channel mutations – Potassium channel mutations – Chloride channel mutations

MCQ-4

• Which of the following abnormality is associated with ‘Juvenile Myoclonic Epilepsy’?

– Sodium channel mutations – Calcium channel mutations – Potassium channel mutations – Chloride channel mutations

MCQ-5

• Which of the following abnormality is associated with ‘Temporal lobe epilepsy’?

– Sodium channel mutations – Calcium channel mutations – Potassium channel mutations – Chloride channel mutations

MCQ-5

• Which of the following abnormality is associated with ‘Temporal lobe epilepsy’?

– Sodium channel mutations – Calcium channel mutations – Potassium channel mutations – Chloride channel mutations

MCQ-6

• Pathophysiologically, which is the most important reason for the precipitation of seizure?

– Increased Glutamate, increased GABA – Increased AMPA, increased GABA – Increased Glutamate, decreased GABA – Decreased Glutamate, increased GABA

MCQ-6

• Pathophysiologically, which is the most important reason for the precipitation of seizure?

– Increased Glutamate, increased GABA – Increased AMPA, increased GABA – Increased Glutamate, decreased GABA – Decreased Glutamate, increased GABA

MCQ-7

• Clinically, the most relevant epilepsy classification system is: – ILAE 1985 – ILAE 1989 – ILAE 1991 – ILAE 2006

MCQ-7

• Clinically, the most relevant epilepsy classification system is: – ILAE 1985 – ILAE 1989 – ILAE 1991 – ILAE 2006

MCQ-8

• Which of the following is not a localization related epilepsy?

– Benign childhood epilepsy with centrotemporal spikes – Juvenile myoclonic epilepsy – Childhood epilepsy with occipital paroxysms – Primary reading epilepsy

MCQ-8

• Which of the following is not a localization related epilepsy?

– Benign childhood epilepsy with centrotemporal spikes – Juvenile myoclonic epilepsy – Childhood epilepsy with occipital paroxysms – Primary reading epilepsy

MCQ-9

• Which of the following is not an idiopathic generalized epilepsy?

– Juvenile absence epilepsy – Epilepsy with grand mal seizures on awakening – Childhood absence epilepsy – Lennox-Gastaut syndrome

MCQ-9

• Which of the following is not an idiopathic generalized epilepsy?

– Juvenile absence epilepsy – Epilepsy with grand mal seizures on awakening – Childhood absence epilepsy – Lennox-Gastaut syndrome

MCQ-10

• Which is the most important differential diagnosis of ‘first seizure’?

– Migraine without aura – Abdominal migraine – Syncope – Migraine with aura

MCQ-10

• Which is the most important differential diagnosis of ‘first seizure’?

– Migraine without aura – Abdominal migraine – Syncope – Migraine with aura

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