AP Biology (An Introduction)
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Transcript AP Biology (An Introduction)
AP Biology
(An Introduction)
Mr. Boswell
Room 208
CUSTOMARY INTRODUCTION
TO
COLLEGE BIOLOGY
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INTRODUCTION TO
21ST CENTURY SCIENCE
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Molecular Biology Revolution
Have you heard about it?
Increase life span
Increase quality of life
Compare to The Internet
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Alba – GFP bunny
Expired in 2002
“Transgenic art”
AP Lab #6
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Human Genome Project
Completed in 2003
Joint Genome Institute (Walnut Creek, CA)
Sequenced entire human genome (DNA)
Cost $2.7 billion
2004, Celera (J. Craig Venter) = $300,000,000 (11%)
2010, Illumina (San Diego, CA) = $14,500 (0.0005%)
2013, $1,000 or less (estimate)
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“We are now part of an early radical
biological revolution that will dwarf the
industrial revolution.”
-- Julian Savulescu (Oxford University)
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Futurama
Last year – Juan Enriquez video
Now it is outdated
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st
21 Century Therapies
Gleevec – Chronic Myelogenous Leukemia
1 pill a day
Sprycel & Tasigna
BrCa-1 and BrCa-2 gene tests for breast and ovarian
cancer
In 2010, Oncept DNA Vaccine
Canine Oral Melanoma
Transdermal application
June 2010, “siRNA ‘Cure’ for Ebola?” (Geisbert et al.)
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Venter Institute
August 2009 – 1st Genetically Engineered
Organism
Altered Yeast genome bacterium
May 2010 – Four bottles (ACTG) + signals = Fully
functional Mycoplasma mycoides genome
Not just engineering bacteria, but creating
them
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http://2011.igem.org/Main_Page
http://ung.igem.org/Team_List?year=2011
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Tracheal Replacement
Lab made organ implanted for first time
Trachial Cancer patient
Not tissue derived from patient, entirely
foreign materials
Made in London, UK Stockholm,
Sweden
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What does this mean?
2008 Plastic Surgeons performed 10.2 Million
procedures
Corrections, deletions, augmentations, & enhancements
What will happen when you can design organs, limbs,
...?
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Hugh Herr
"When you go into my closet, there are many,
many pairs of legs. I have a running pair, I
have a bionic walking pair, limbs that are
waterproof," he says. "I have various legs to
climb mountains and to sense steep ice walls,
other feet that wedge into small rock fissures
[and] others that stand on small rock edges
the width of a coin.”
“My biological body will degrade in time…,
but the artificial part of my body will improve
over time since I can upgrade.”
http://www.npr.org/2011/08/10/137552538/the-doubleamputee-who-designs-better-limbs
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iPSCs (Induced Pluripotent Stem Cells)
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Engineering Humans
Engineering Children
Already determine gender & eliminate some diseases
What amount of intelligence will your child have?
Will you give them the 577R genotype in the ACTN3
gene?
84% of Africans have it, 49% of Eurasians have it
What about Olympic athletes?
Engineering Adults
Hear ultrasound frequencies
Telescopic vision
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INTRODUCTION TO AP BIOLOGY
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Exit Interview Comments
“…take the class only if you enjoy biology or the
sciences.”
“If he/she doesn’t wish to go into the field of science,
I’d highly dissuade them from taking the course.”
“If a student is only taking a course to have it on her
transcript then she will have a horrible time.”
“…you must learn a ton of information in a short
period of time.”
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Page 2
“AP Biology is nothing like honors Biology.”
“…the teacher should have removed students from the
class who were not up to the standards of the course.”
“Some people played on the computer or did not pay
attention in class. Why are they still here?”
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2010 AP Biology Results
Pass Rate = 90%
“5”s = 52%
“5” + “4” = 77%
Students = 64
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Why this class is difficult…
1. Biology knowledge base is deficient
How many years ago did you take Honors Biology?
2. Honors Biology ≠ AP Biology
3. 55 Chapters (1,230 pages)
4. 3 credits vs. 8 credits
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Why this class not difficult…
1. Clear expectations
Vocabulary & Objectives
2. Information is readily available
3. Course Materials sourced from 3 Biology textbooks
4. Course materials are easily accessible
5. Few complicated concepts
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What is a College Level Course?
Student-Driven Learning
Role of teacher is to highlight some important points
Will NOT cover every concept in class
“students are expected to work independently outside
the class”
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Q1
Biochemistry
Cells
Energetics
Classical Genetics
Molecular Genetics
DNA Technology & Genomics
Q3
Animal & Human Physiology
Ecology
Evolution
Free-Response Questions
CHAPTERS 21-25 & 42-55 [18]
CHAPTERS 1 – 20 [20]
Q2
Q4
Labs 1-6
Classification
Plant Physiology
Basic Systems
Review for AP Exam
CHAPTERS 26-40 [14]
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Class Discussions
You WILL be called on to attempt an answer
I want to hear what you have to say
Make all questions and comments relevant to the
content discussion
If your question is off topic, write it down and ask it later
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INTRODUCTION TO MR. BOSWELL
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Background
Undergrad: Philosophy & Biochemistry
Masters: Medical Economics & Epidemiology
HHMI (Howard Hughes Medical Institute) Cohort
Inaugural Fellow (2008) @ University of Florida
Translational Medicine Institute (2011) @ UF
AP Summer Institute (2007, 2008, & 2009)
Nova SE, BCPS, and Stanford University
AP Annual Conference (2008) in Seattle, WA
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Schedule
PERIOD
COURSE
1
AP Biology
2
AP Biology
3
AP Biology
4
Honors Biology I
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Assignments
Diagnostic Test due by 2:00 am Tonight !!!
Biology: Diagnostic Test – (45 minutes)
http://www.quia.com/quiz/3231852.html
Student Information Survey
http://www.quia.com/sv/540447.html
Any questions on the Student Survey, email me @ bb@ap-
bio.com
Due by 2:00 am Tonight !!
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Assignment (Page 2)
http://www.ap-bio.com
Student Handbook 2011: Printout, Read, & then Sign
Due Wednesday 8/24/11
Statement of Understanding (Page 4)
Lab Safety Contract (Page 4)
Academic Integrity (Honor Code) (Page 5)
AP Exam Exception (Page 6)
Homework / Summer Project
Due in class Wednesday 8/24/11
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Assignment (Page 3)
If you have not gotten emails from Mr. Boswell, make
sure you add name to email list
Chapters 2 & 3 tomorrow
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