Transcript Slide 1
Legume Genetics and Sport & Exercise Science What’s the connection? Noel Ellis http://www.aber.ac.uk/en/ibers/staff/staff-list/noel_ellis/ Food legumes: peas, beans, lentils, ... Protein Carbohydrate Oil Fibre Minerals high for plant derived food variable variable generally quite high various e.g. Se What’s the connection? The Olympic Games (of course) Pisa Olympia The inhabitants of Pisa founded the Olympic games in 776 BC & organised them until 572 BC. Pisum derives from Pisa where archaeological remains show that peas were cultivated by the ancient Greeks Sherwood (1898) Garden Peas J.RHS 22: 239-260 Three things I am going to say Food legumes are diverse, with useful nutritional properties Food composition can be controlled genetically This means we can define the genetics of nutritional properties and use this to create or identify functional foods. Glycaemic index: staying power not all starches are the same 6 The glycaemic potency of breakfast and cognitive function in school children. Micha et al. Eur J Clin Nutr. 2010 64: 948-57. Nutritional Sciences Research Division, King's College London ΔPlasma glucose mmol/l 4 2 mung bean starch 0 maize starch glucose -2 -4 0 1 2 Modified from Rizkalla et al. (2002) Brit. J. Nutr. 88 S255-S262 3 4 hrs Starch synthesis: genetic variation WT r rb rug3 rug4 rug5 lam WT SBE1 ADPG PGMP SUS2 GBSSII SSI all of these wrinkled seed mutants are defective in an enzyme involved in starch synthesis. Hedley et al (2002) Starch/Stärke 54 235–242 Starch: genetic variation consequence for fibre Raffinose rb Rb Sucrose progeny of the cross: JI281 x JI399 Domoney & Charlton pers. comm. Raffino-oligosaccharides: RFOs α-galactosides sucrose raffinose - flatus etc. stachyose Guillon & Champ (2002) Brit. J. Nutr. 88 S293-S306 + prebiotic claimed control of Clostridium, Salmonella & colon tumors (in rats) it is not only starch that has changed so has the protein profile. Legumin R/Rb r/rb rb r Starch: genetic variation Vicilin 70kD mg/g 40 Vicilin 50kD Legumin 40kD 20 Casey et al. (2001) Nahrung/Food 45 385-387 r rb r/rb R/Rb r rb r/rb R/Rb 20kD Metabolite profiling Genetic mapping of determinants of NMR spectral differences Segregation of NMR peak intensity 20 RILs from JI281 x JI399 NMR peak index (7.92 – 8.03 ppm) Charlton, Domoney et al pers. comm. PCGIN Pulse Crop Genetic Improvement Network QDiPS Thanks to: Julie Hofer Claire Domoney Adrian Charlton Two views http://www.21food.com/ ‘Peas have great diversity’ George Orwell, The Road to Wigan Pier