Transcript Panel Experience - Life Sciences Research Organization

Goals For This Meeting
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Receive input and comment on the recent
literature regarding the potential adverse
health effects of dental amalgams (to the
LSRO and the Expert Panel)
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Provide background to Expert Panel
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Report on the process and current thinking
(to the stakeholder communities)
Goals For This Project
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Identify and evaluate recent literature
Provide scientific, evidence-based
opinion on the potential adverse health
effects of dental amalgam
Not recommending public policy
General Procedures
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Time frame: Summer 2003 – Spring
2004
Call(s) for public comment
Selection of Expert Panel
Transparent process
Publicly available report
Restricted communication
Expert Panel
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Selection principles
Recognized scientific authorities
 Disciplinary expertise
 Un-biased – excluded:
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Dental community
 Previously expressed opinion
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Selected and appointed by LSRO
Expert Panel
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Meryl Karol, PhD (Chair)
U of Pittsburgh
Stanley Berent, MS, PhD
U of Michigan
Robert Brent, MD, PhD
Thomas Jefferson U
James Bruckner, MS, PhD
U of Georgia
John Doull, MD, PhD
U of Kansas Med School
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M. Eric Gershwin, MD
U Cal School of Med
Ronald Hood, MS, PhD
U of Alabama
Genevieve Matanoski, MD, DrPH
Johns Hopkins U
Raphael Rubin, MD
Thomas Jefferson U
Bernard Weiss, PhD (Consultant)
U of Rochester
Panel Experience
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Past presidents of toxicology societies
Editors of major scientific journals
Department chairs
Endowed professorships
Authors of preeminent textbooks
Authors of thousands of publications
Members of advisory & NAS panels
Recipient of numerous awards
Panel Expertise
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Toxicology (5)
Neuro/behavioral
toxicol (2)
Pathology (1)
Allergy (1)
Immunology (2)
Pediatrics (1)
Developmental tox (3)
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Reproductive tox (1)
Psychology (1)
Epidemiology (2)
Public health (2)
Environmental and
occupational health (2)
Toxicokinetics (1)
Risk assessment (1)
Panel Experience
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Past presidents of toxicology societies
Editors of major scientific journals
Department chairs
Endowed professorships
Authors of preeminent textbooks
Authors of thousands of publications
Members of government advisory & NAS
panels
Recipient of numerous awards
Restricted Communication
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Communicate with the Panel through
LSRO
Maintain transparency
 Eliminate bias
 Ensure the entire panel receives all input
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Panel reports any unofficial or ex parte
communication
Miscellany
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LSRO staff will write the report
Report will express Expert Panel consensus
and will not attribute individual opinions
 Attempt to reach consensus wording
 If necessary include minority opinions
Post presentation slides on our web site