Transcript Perinatal HIV Epidemic: Situation Analysis

Perinatal transmission of HIV
Globally, in the United States, and in Wisconsin
Wisconsin Department of Health Services
AIDS/HIV Program
September 2014
Estimated numbers of perinatally acquired AIDS cases
by year of diagnosis, 1985–2010 — United States and
dependent areas
1,000
No. of cases
800
600
400
200
0
1985
1987
1989
1991
1993
1995
1997
1999
2001
2003
Year of diagnosis
Note: Data have been adjusted for reporting delays and missing risk-factor information.
2005
2007
2009
2011
Number of new HIV infections among children in low- and middleincome countries, 2001-2012 and 2015 target
52% decline, 2001-2012
Target 90% decline, 2009-2015
Source: UNAIDS 2012 estimates
Wisconsin cases (n=132)
• Cases of HIV diagnosed in children under age 15
• Perinatal or unknown risk exposure
– Exposure for most (n=112): mother-at-risk.
– Unknown risk exposure (n=20) if HIV test result of mother is
not available and risk is not identified as MSM, IDU,
heterosexual, hemophilia, or transfusion.
• Years of diagnosis, 1984-2013
• Places of birth:
– Wisconsin, other U.S. state, or foreign country.
Cases of HIV in children under age 15 with perinatal or
unknown risk exposure, by year of diagnosis and place
of birth, Wisconsin, 1984-2013 (n=62)
Place of birth
14
12
10
8
6
4
Year of HIV Diagnosis
Source: Wisconsin HIV Surveillance System
2013
2012
2011
2010
2009
2008
2007
2006
2005
2004
2003
2002
2001
2000
1999
1998
1997
1996
1995
1994
1993
1992
1991
1990
1989
1988
1987
0
1986
2
1984
Number of Diagnoses
Wisconsin
Cases of HIV in children under age 15 with perinatal or
unknown risk exposure, by year of diagnosis and place
of birth, Wisconsin, 1984-2013 (n=95)
Place of birth
12
Other US state
10
Wisconsin
8
6
4
Year of HIV Diagnosis
Source: Wisconsin HIV Surveillance System
2013
2012
2011
2010
2009
2008
2007
2006
2005
2004
2003
2002
2001
2000
1999
1998
1997
1996
1995
1994
1993
1992
1991
1990
1989
1988
1987
0
1986
2
1984
Number of Diagnoses
14
14
Place of birth
12
Foreign Country
Other US state
10
Wisconsin
8
6
4
Year of HIV Diagnosis
Source: Wisconsin HIV Surveillance System
2013
2012
2011
2010
2009
2008
2007
2006
2005
2004
2003
2002
2001
2000
1999
1998
1997
1996
1995
1994
1993
1992
1991
1990
1989
1988
1987
0
1986
2
1984
Number of Diagnoses
Cases of HIV in children under age 15 with perinatal or
unknown risk exposure, by year of diagnosis and place
of birth, Wisconsin, 1984-2013 (n=132)
Vital status of HIV diagnoses under age 15 with
perinatal or unknown risk exposure ever reported in
Wisconsin, 2013 (n=132)
Died, age 5 or
older
8%
Died before age 5
12%
Alive
80%
Source: Wisconsin HIV Surveillance System
Cases of HIV in children under age 15 with perinatal or unknown
risk exposure in Wisconsin: Summary
Diagnoses
1984-2013
(n=132)
2009-2013
(last 5 years; n=20)
Born in Wisconsin
62
4
Born in another US state
33
0
Born in foreign country
37
16
Deaths 1984-2013
n=26
In cases diagnosed before Year 2000
n=25
(Median age = 3)
In cases diagnosed Year 2000 or later
n=1
(Adult)
Prevalent cases as of December 2013
Source: Wisconsin HIV Surveillance System
n=106
(Median age = 3)
(Current age 15: n=39)
Cases of HIV in children under age 15 with perinatal or
unknown risk exposure, by decade of diagnosis and
place of birth, Wisconsin, 1984-2013 (n=132)
Place of birth
35
30
Wisconsin
29
Number of Diagnoses
26
25
28
Other US state
23
Foreign country
20
15
9
10
7
6
5
3
1
0
1984-1993 (n=58)
1994-2003 (n=38)
Year of Diagnosis
Source: Wisconsin HIV Surveillance System
2004-2013 (n=36)
As of 2012, nearly 15 million
children under 18 years of age in
sub-Saharan Africa have lost one
or both parents to HIV.