Transcript Slide 1

Experience, Expertise and a Commitment to Excellence™

Protons - Superior Dose Distribution

 The Bragg Peak is representative of a delivery of a full, localized, and uniform dose of energy in the target 4 3 2 1

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0 10 20 Depth in Tissue (cm)

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System Components

      The Synchrotron Accelerator The Beam Transport System The Stationary Beam Gantries (Isocentric Gantries) Patient Alignment and Digital Imaging Systems Facility Control System

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Facility Layout

The Loma Linda University Medical Center Proton Treatment Center

The Gantries:

Has two branches: •Eye Tumors •Head and Neck Resembling giant ferris wheels can rotate around the patient and direct the proton beam to a precise point. Each gantry weights about 90 tons and Tumors stands 3 stories tall. It supports the bending and focusing magnets to direct the beam.

The Injector:

Protons are stripped out of the nucleus of hydrogen atoms and sent to the accelerator.

Steel reinforced concrete walls are up to 15 feet thick.

Synchrotron: (Accelerator)

A ring of magnets, 20 ft. in diameter, through which protons circulate in a vacuum tube.

Beam Transport System:

Carries the beam from the accelerator to one of four treatment rooms. This system consists of several bending corners and focus it to the desired location .

Proton Accelerator Control System

Conforma 3000 Integrated Solution

 Treatment Control System (TCS)  Accelerator Control System (ACS)   Treatment Workstation Integrated and Automated  “The Brain”  Software & Electronics for Treatment Precision  Accelerate  Deliver  Control

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Accelerator Control - Advantages

    Automatic Beam Centering in Treatment Nozzle  Key to Active Beam Scanning Rapid Beam Line Switching  <10 sec.

Accurate, Reproducible Beam Energy  Within 0.1 MeV Patented Safety Systems  Ensure Beam is Delivered at the Right Place & Time

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      Integrated and automated Rotates >360 o Treatment from multiple “portals” or angles Isocenter is contained within a sphere  to 1.0 mm in radius Automated set up Designed for functionality

Gantry Treatment Room

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Conforma 3000 Passive Scattering Beam Delivery System Compensator (Bolus) and Block (Aperture) Dose and Flatness Monitor(s) Range Modulation Wheel X-ray Tube Second Scatterer First Scatterer Profile Monitor Beam Movable Snout (cones)

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Redundant Dose Detectors Optional Compensator (Bolus) and Block (Aperture) Movable Snout (cones) Conforma 3000 Active Beam System Intensity Modulated Proton Therapy IMPT or Active Beam Scanning (ABS)  Supports Compensator-less treatments  Variable energy controls penetration depth  Capable of continuous (raster scanning) & discrete point based (“Spot” scanning) Scanning Magnets Radiographic Imaging Panels (2)

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Beam

Intensity Modulated Proton Therapy

  Ability to Treat Complex Volumes & Multiple Target Areas “Spot Scanning” Technique  Beam scans from the top down  Radiation deposited from side to side

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Modular Design (4 gantry, 2 Stationary)

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Treatment Planning Software

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Contact Information

Jon Slater, President & CEO 909.799.8333

[email protected]

Mike Martin VP of Sales 513.518.8037

[email protected]

Daryl Anderson Chief Financial Officer 909.799.8342

[email protected]

Ken Rice Director of Computer Science 909.799.8318

[email protected]

David Lesyna VP Engineering 909.799.8312

[email protected]

www.optivus.com

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