Exploration of Possible Interest in a Cholesterol

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The Use of Oral Anticoagulant Medications: Survey of Physicians: Key Findings

Prepared for:

The National Consumers League

September 20, 2005

J23716

Table of Contents

Background & Objectives . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 Sample and Methodology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5 Key Findings . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6 Respondent Profile . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 49

2

Background and Objectives: Physicians

• The physicians survey is the final phase of a research project designed to inform the development of an outpatient medication safety campaign aimed at consumers, caregivers, and physicians. The physician survey was designed to gain insight into the physician’s point of view about issues around the use and management of oral anticoagulant medication

.

3

Background and Objectives, continued

• Specific areas of inquiry include:

– Treatment and counseling of patients on oral anticoagulants.

– Patient experiences with oral anticoagulant regimen.

– Ongoing treatment and monitoring patients 4

Sample and Methodology

• This survey was conducted online within the United States with members of the Harris Interactive Physician Panel.

• Interviews were conducted between August 11, 2005 and August 18, 2005.

• A total of 101 physicians were interviewed. – Eligible respondents were practicing medicine in the U.S.: • Primary care providers (specializing in family practice, internal medicine or general medicine) and cardiovascular specialists; • Practicing for at least 5 years and spending at least 70% of their time in direct patient care; • Treating 5 or more patients who are on an oral anticoagulant medication.

• Eligible received received an honorarium of $50 for completing the survey.

5

Summary of Key Findings

6

Summary of Key Findings: Physicians

1.

2.

3.

4.

5.

Managing patients on anticoagulant medication is a challenge for physicians.

Most physicians feel that the effort to manage multiple conditions and medications is the main reason why oral anticoagulant patients experience difficulties with their regimen.

There is room for improvement in communication by physicians about oral anticoagulant regimen requirements and blood test results.

Physicians could be doing more to help their patients with ongoing management of their oral anticoagulant regimen.

Improving blood testing, communication, and involvement with health care professionals are seen as key components in helping patients comply with their oral anticoagulant regimen .

7

Case Study

• We asked physicians to tell us about their most recent visit with a patient on oral anticoagulant medication.

• This review gives us a glimpse into both the “average” patient on anticoagulant medication and the important exceptions.

• It also gives us insight into what physicians are routinely doing to help manage their anticoagulant patients.

• We will first present findings from this case study, focusing both on the average patient and the crucial exceptions.

• We will then elaborate on key findings, which are illustrated by this case study.

8

Case Study: Gender and Age

Most anticoagulant patients are male, but many are female.

Male 60% Female 40%

The average anticoagulant patient is 64 years old.

Less than 35 years 35-44 2% 6% 45-54 65-74 75 or older 19% 26% 30% Q505

For the next few questions, we would like you to think about the most recent visit that involved a patient who is taking an anticoagulant medication. Is this patient…?

Base: Qualified Respondents (n=101)

Q511

Approximately how old is the patient?

Base: Qualified Respondents (n=101)

9

Case Study: Primary Condition

Atrial fibrillation Blood clot, thromboembolism, or pulmonary embolism Heart valve replacement Peripheral vascular disease 2% Heart failure 2% Stroke or stroke-like symptoms 1% A high red blood cell count (polycythemia) 1% Trans-ischemic attack (TIA) 0% 9% 26% Other 4%

Q510 What is the primary condition for which this patient was prescribed an anticoagulant medication?

Base: Qualified Respondents (n=101)

55%

The average patient is taking an oral anticoagulant for atrial fibrillation.

10

Case Study: Type of Oral Anticoagulant Medication

The anticoagulants most often taken are Coumadin or Jantoven and Warfarin.

57% 40% Coumadin or Jantoven Warfarin 1% Dicumarol 1% Sintrom or Acenocoumarol 0% Miradon or Anisidione 1% None of these

Q520 Please indicate the name of the patient’s anticoagulant medication.

Base: Qualified Respondents (n=101) 11

Case Study: Length of Time on Medication

First time prescribed Less than 3 months 3 – 6 months 7 - 11 months 1 – 2 years 3 – 4 years 5 years or more 6% 8% 15% 16% 15% 12%

Q515 For approximately how long has this patient been taking the oral anticoagulant ?

Base: Qualified Respondents (n=101) Typical anticoagulant patients are in all stages of treatment longevity. More than half have been taking the medication for a year or longer.

29% 56%

12

Case Study: Length of Treatment

Less than 6 months 5% 7 - 11 months 9% 1 - 3 years 3% A lifetime Not sure 2% Q517 In your opinion, for how long will the patient need to remain on this therapy?

Base: Qualified Respondents (n=101) The large majority of these patients will be taking an oral anticoagulant for the rest of their lives.

81% 13

Case Study: Frequency of Physician Visits

Within the last week Within the last 2 weeks Within the last month Within the last 3 months 3 – 6 months ago Over 6 months ago 1% First visit 3% 13% 11% 13% 26% 33% 57%

More than half of anticoagulant patients have been to see their doctor more than once in the last month. Q525 Prior to this visit, how long ago was this patient’s last visit?

Base: Qualified Respondents (n=101) 14

Case Study: Reason for Recent Visit

Most doctor visits are for routine care, but visits in reaction to a problem are not uncommon.

Visit was for routine care 74% Visit was response to event or problem 26%

Q526 Was this patient’s most recent visit for routine care or related to an event or some type of problem he/she was having?

Base: Qualified Respondents (n=101) 15

Case Study: Communication During Physician Visit

While physicians are doing well with reviewing medication during patients’ visits, many patients are not being asked about compliance, problems they may be having, and diet.

On this patient’s most recent visit did you…?

Review the patient’s latest blood test results Review all of the patient’s medications, including over-the counter medications, vitamins and supplements Ask the patient whether he/she is taking the oral anticoagulant as prescribed Ask the patient whether he/she is having any problems related to taking the oral anticoagulant Ask the patient about his/her diet

Yes %

96 84 83 79 50

No %

4 14 17 20 49

Not sure %

2 1 1 Q529 On this patient’s most recent visit did you…?

Base: Qualified respondents (n=101) 16

Case Study: Number of Physician Visits in Past 12 Months

The average anticoagulant patient visits the doctor 7 times a year.

7 8 9 10 11 12 More than 12 1 2 3 4 5 6

0% 1% 2% 5% 5% 5% 6% 8% 11% 16% 16% 15% 19% Not sure: 2% Q531 888. How many times have you seen this patient in the past year? If you are not sure, your best estimate will do. If you don’t know, please enter Base: Qualified Respondents (n=101) 17

Case Study: Compliance with Medication Regimen

The large majority of patients take their anticoagulant medication as prescribed.

Yes 92% No 3% Not sure 5%

% of physicians reporting that patient is taking medication as prescribed Q540 To the best of your knowledge, is this patient taking his/her anticoagulant medication as prescribed? Base: Qualified Respondents (n=101) 18

Case Study: Compliance with Blood Testing

Never 1% Sometimes 2% Most of the time Always Too early to tell 3% Have not made any recommendations 1% 48% 46% 48%

About half of patients could use improvement in compliance with their doctor’s recommendations for blood testing. Q545 Does this patient follow your recommendations to have his/her blood tested regularly? Base: Qualified Respondents (n=101) 19

Case Study: INR in Desired Range

1 in 4 patients INR is

not

consistently in the desired range.

No 25% Yes 62% Too early to tell 11% Not sure 2%

% of physicians reporting that patient’s INR is consistently in the desired range Q550 Is this patient’s INR consistently in the desired range? Base: Qualified Respondents (n=101) 20

Case Study: Patient’s Management of Oral Anticoagulant Regimen

Almost half of patients are managing their anticoagulant regimen

less than

very well.

Extremely well 19% Very well Fairly well 31% 33% Somewhat well Not at all well 2% 15% 48% Not sure 1%

% of physicians indicating how well the patient is managing oral anticoagulant use Q555 Overall, how well do you think this patient is managing his/her oral anticoagulant? Base: Qualified Respondents (n=101) 21

Case Study: Ease in Following Treatment Recommendations

1 in 4 patients have a very or somewhat difficult time following their doctor’s recommendations related to their anticoagulant regimen.

Very easy 29% Somewhat easy Somewhat difficult Very difficult 2% 24%

26%

45% Not sure 1%

% of physicians indicating how difficult it is for the patient to follow all of their recommendations Q560 To the best of your knowledge, how easy or difficult is it for this patient to follow all of your recommendations related to taking his/her oral anticoagulant? Base: Qualified Respondents (n=101) 22

Case Study: Caregivers

45% of patients have a caregiver assisting with their medication management. For 1 in 10 patients, the physician does not know if a caregiver is involved.

No 45% Yes 45% Not Sure 11%

% of physicians who say that patient has assistance in anticoagulant management Q565 To the best of your knowledge, does this person have a family member or other caregiver who is actively involved in assisting with his/her oral anticoagulation management? Base: Qualified Respondents (n=101) 23

Key Finding #1: Managing patients on anticoagulant medication is a challenge for physicians.

• • • • • Compared to other chronically ill patients, oral anticoagulant patients require more time spent adjusting medication, reviewing and relaying test results and other consultations.

Two in five patients suffered a significant life-threatening event that precipitated treatment with blood thinning medication.

Side effects or problems due to oral anticoagulant use are not uncommon. Majorities of physicians report that their oral anticoagulant patients have had problems due to their anticoagulant medication. In general patients called and/or visited the physician’s office, however, more than half of physicians report the their patients went to the emergency room and/or the hospital as a result of these complications.

Physicians frequently have to make adjustments in dosage and counsel patients about guidelines because of problems related to their oral anticoagulant use.

Physicians see patient non-compliance with their medication and blood testing regimen as the biggest challenges they face in managing these patients.

24

Chart 1: Anticoagulant patients require more of physicians’ time than other chronically ill patients.

Time anticoagulant patients require: Much less time % Some-what less time % About the same amount of time % Some what more time % Much more time % Net of more time %

Amount of time adjusting medication The amount of time I need to review and relay their test results The amount of time I have to spend with the patient (both in person and on phone/email consultations) The amount of time that other staff in my practice need to spend with the patients 1 3 5 6 4 17 26 27 34 51 48 53 39 28 22 14 22 79 69 67 60 Q605 Compared to your patients on other medications for other chronic conditions (such as diabetes, arthritis, chronic lung disease, heart condition, or high blood pressure), do you find that your oral anticoagulant patients require more or less time from you or your staff for the following activities? Base: Qualified Respondents (n=101) 25

Chart 2: More than two in five physicians report that more than half of their patients suffered a significant life-threatening event that precipitated treatment with blood thinning medication.

Proportion of patients that had a significant life-threatening event that precipitated the decision to initiate therapy <5% of patients 6 - 10% 11 - 25% 26 - 30% 31 - 40% 41 - 50% 51 - 60% 61 - 70% 71 - 80% 81 - 90% 91 - 100%

3% 6% 3% 7% 5% 8% 12% 11% 12% 13% 20% 41% of physicians say that more than half of patients experienced a life-threatening event Q404 Proportion of patients that had a significant event Base: Qualified respondents (n=101) 26

Chart 3: Majorities of physicians report that their patients experienced problems with their anticoagulant medication, leading to doctor visits and trips to the emergency room or hospital.

Called the office Visited the office Went to ER Went to hospital None of these

7% 52% 51% 84% 82% Q440 In the past 12 months, have any of your patients done any of the following because of a problem related to taking their oral anticoagulant medication? Base: Qualified respondents (n=101) 27

Chart 4: Physicians frequently have to make adjustments in dosage and counsel patients about guidelines because of problems related to their oral anticoagulant use.

Percentage of physicians who do the following because of patient problems related to taking oral anticoagulants:

Advised/Reminded patient to follow recommended guidelines for his/her treatment regimen (e.g. compliance, diet, regular blood testing, etc.) Adjusted dose of oral anticoagulant Suggested adjustments to use of over-the-counter medications, vitamins, or supplements the patient was taking in addition to his/her oral anticoagulant Made adjustments to another prescription medication that patient was taking in addition to his/her oral anticoagulant Switched patient to another brand of anticoagulant

Every time % Less than Every time %

22 15 8 79 86 91 4 2 96 96 Q445 Thinking about all of your patients on oral anticoagulants, how often have you had to do the following because of a problem related to their oral anticoagulant medication?

Base: Qualified Respondents (n=101) 28

Chart 5: Physicians feel that patient non-compliance with medication regimen and recommended blood tests are the top challenges when dealing with oral anticoagulant patients.

Percent who indicated items as one of top 3 challenges Patients not being compliant with the medication regimen Patients not getting their blood tested as directed Interactions with drugs prescribed by other physicians Patients not returning for follow-up visits Patients not following a consistent diet Patients taking OTCs that they should avoid Problems getting lab results Problems resulting from use of generic versions Pharmacies that change the supplier of their generic versions Patients not reporting symptoms or complications Problems reaching or communicating with pharmacists about patients None of these

4% 2% 16% 15% 15% 11% 30% 27% 26% 39% 48% 46% Q610 Thinking about your experiences managing patients who take oral anticoagulants, which would you say are the biggest challenges you face? Base: Qualified Respondents (n=101) 29

Key Finding #2: Most physicians feel that the effort to manage multiple conditions is the main reason why oral anticoagulant patients experience difficulties with their treatment regimen.

Nearly two in three physicians (61%) believe that managing multiple health problems is the number one reason why patients have difficulties with their anticoagulant treatment regimen.

Lack of patient motivation to follow recommendations is also seen by many doctors as a key reason for problems.

Lack of patient information about requirements when taking an oral anticoagulant and too little time to spend with these patients also seen as factors.

30

Chart 6: Physicians see management of multiple conditions and non-compliance with recommendations as the main factors leading to patient problems.

Percent indicating items as top 1 or 2 reasons that patients experience difficulties with their regimen These patients are trying to manage multiple conditions and medications, in addition to their anticoagulant Patients are not motivated to follow medication and testing recommendations because there are no immediate and clear rewards for treatment compliance Patients lack information about what they should or should not do while taking an oral anticoagulant Physicians and other providers do not have enough time to closely monitor the progress of these patients These patients are receiving conflicting advice from various sources 10% 24% 22% 43% 61% Other barriers 17%

Q615 What do you think are the main reasons why patients taking oral anticoagulants experience difficulties with their regimen? Base: Qualified Respondents (n=101) 31

Key Finding #3: There is room for improvement in communication by physicians about oral anticoagulant regimen and blood test results.

• • • • • • • Many physicians do not tell all their patients important information such as dietary considerations and potential drug interactions when they first start them on anticoagulant medication.

One in three physicians do not provide any of their oral anticoagulant patients with written instructions.

While most physicians receive INR test results within 24 hours, a large minority has to wait at least two days.

One in four physicians do not always call or mail the patients to inform them about their INR test results.

One in five of the most commonly questions asked by patients relates to INR results and the frequency of blood testing. Very few physicians leave a message with the patient’s INR results, most will wait until they have made personal contact with the patient.

When informing their patients about INR test results, many physicians do not tell their patients the actual numeric INR value.

32

Chart 7: Many physicians do not tell their patients important information such as dietary considerations and potential drug interactions when they first start patients on and anticoagulant medication.

Issues that doctors talk about when initiating oral anticoagulant medication for the first time:

Tell them about any special dietary considerations they should know while taking this medication Explain potential interactions between the oral anticoagulant and other prescription or over-the-counter medications, vitamins or supplements Explain any side effects they may experience Tell them about symptoms to watch for and when to seek further care or treatment Give them specific instructions about how to take the medication Tell them about how often they should have their blood tested Explain why they need to take it Advise them to wear a medical information emblem (bracelet or identifier) or carry a piece of paper that indicates the name of their anticoagulant medication

Less than every time %

44 42 34 28 28 20 15 83

Every time %

47 59 66 74 72 80 85 16 Q402 First, please think about the situations when you start a patient on an oral anticoagulant or when you see a patient immediately after he or she has been started on an oral anticoagulant in a hospital. In these situations, how often do you talk to your patients about the following issues when you give them an oral anticoagulant prescription for the first time. Base: Qualified respondents (n=101) *1% not sure 33

Chart 8: One in three physicians do not provide any of their oral anticoagulant patients with written instructions.

Yes, give written instructions to all patients taking an anticoagulant Yes, give written instructions to some patients taking an anticoagulant No, do not give written instructions 31% 32% 38% Q407 Do you or does someone else in your office give written instructions about taking anticoagulant medications to your patients? These written instructions may inform patients about what they should and should not do with regard to diet, concomitant prescription and over-the-counter medication use, blood tests , etc. Please do not include the informational insert that comes with the medication or from the drug maker.

Base: Qualified respondents (n=101) 34

Chart 9: While most physicians receive INR test results within 24 hours, a large minority has to wait at least 2 days for them.

Within 24 hours

77%

Within 3 days

3%

Within 48 hours

20% Q420 On average, how soon after testing do you receive your patients’ INR results from the lab?

Base: Qualified respondents (n=101) 35

Chart 10: One in four physicians do not always call or mail the patients to inform them about their INR test results.

I or someone else in my office always call patients with INR results.

I or someone in my office call patients with INR results, but only when there is a change in the numbers. My office always mails a letter to patients with INR results.

5%

My office mails a letter with INR results, but only when there is a change in the numbers.

2%

My office generally does not contact the patient with INR results.

1%

None of these describe my office’s approach to contacting patients with INR results.

8% 22%

Not sure

0% Q425 Which of the following best describes your office’s general approach to contacting patients regarding their INR results?

Base: Qualified Respondents (n=101). Note: Multiple responses question, respondents could say that they phone and send letters.

67% 36

Chart 11: One in five of the most commonly questions asked by patients relates to INR results and the frequency of blood testing.

Length of time medication needs to be taken/when it can be stopped INR related, thickness of blood/too thick, too thin, OK Reason the medication need to be taken?

Diet/alcohol related Dosing related: missing/changing dosage Danger of treatment/side effects Frequency of blood tests Bleeding related Other Nothing

2% 10% 9% 8% 8% 6% 5% 6% 14% 33%

20%

Q708 What is the most common question your oral anticoagulant patients ask you about their treatment regimen? Base: All respondents (n=101) 37

Chart 12: Very few physicians leave a message with the patient’s INR results, most will wait until they’ve made personal contact with the patient.

Leave a message asking for a return call from the patient Continue to phone the patient until personal contact is made Leave a message with the patient’s INR results Send a note to the patient with his/her INR results None of these

2% 5% 8%

Not sure

2% 37% 46% Q430 If you or another health-care professional in your office cannot reach a patient personally when calling with the INR results, which of the following are you most likely to do? Base: Respondents Who Call Patients With INR Results (n=98) 38

Chart 13: When informing their patients about their INR test results, many physicians do not tell their patients their actual numeric INR value.

Tell them the actual numeric INR value Describe the blood characteristics (e.g., too thick or too thin) Describe the results in terms of “good” or “bad” Other 5% 11% 31% 53% Q435 What terminology do you generally use to describe INR test results to your oral anticoagulation patients? Base: Qualified Respondents (n=101) 39

Key Finding #4: Physicians could be doing more to help their patients with ongoing management of their oral anticoagulant regimen.

• Nearly 2 in 5 physicians do not have a nurse or other health care professional in their office to help patients manage their oral anticoagulant.

• The majority of physician offices do not contact their patients every time to remind them about their next appointment or to have their blood tested.

40

Chart 13: Nearly 2 in 5 physicians do not have a nurse or other health care professional in their office to help patients manage their oral anticoagulant.

Yes, a nurse Yes, another health care professional 18% 46% No 37% Q410 Is there a nurse or another health-care professional in your office who helps patients manage their oral anticoagulant? This may include calling them regularly to check how well they are doing, reminding them about appointments for blood testing, reviewing their blood test results with them, etc. Please do not include a receptionist calling the patient about appointments. Base: Qualified respondents (n=101) 41

Chart 14: The majority of physician offices do not contact their patients every time to remind them about their next appointment or to have their blood tested.

Follow-up contact

Remind them of their next appointment Remind them to have their blood tested To check how well they are doing

Every time %

43 45 21

Less than every time %

56 55 76 Q416 How often, if ever, do you or your office staff contact your oral anticoagulant patients to….?

Base: Qualified respondents (n=101) 42

Key Finding #5: Improving blood testing, communications and involvement with health care professionals are seen as key components in helping patients comply with their oral anticoagulant regimen.

• • • • Physicians report that the most effective ways to help patients comply with their anticoagulant regimen involve improvements in blood testing: – Improving the speed and accuracy of blood testing – Improving communication about blood results Better information for patients and more assistance with management of their treatment are also seen as solutions. Written communication is seen by many physicians as a good method of relaying information. Regular counseling and check ups are also key to conveying the rules and guidelines anticoagulant patients should follow.

Physicians trust clinic staff at anticoagulant clinics and different doctors in their own offices the most to help in the management of their anticoagulant patients.

Continued >

43

Chart 15a: Good communication and information are effective in increasing patients’ compliance with oral anticoagulant medication.

Effective approaches:

Improve the speed and accuracy of blood testing Improving communication about blood results – consistent feedback loop, regardless of whether INR results are good or bad Better information available to patients about what they should or should not do Having more patients visit anticoagulant clinics for routine care Nurses or other health-care professionals providing ongoing disease management for patients Physicians spending more time with patients to provide counseling and support Providing rewards to patients who show perfect compliance with their medication regimen Patient self-testing their blood for INR level Pharmacists spending more time educating and counseling patients

Very Effective %

29 41 24 26 26 42 33 31 37

Extremely effective %

21 11 11 9 7 18 18 16 15

Net 4/5 % 50 51 35 35 33 59 50 47 51

Q620 How effective do you think the following approaches to increasing patient oral anticoagulant compliance would be? Base: Qualified Respondents (n=101) 44

Chart 15b: Patient self-testing and more time spent with patients are seen as less effective approaches.

Effective approaches:

Having more patients visit anticoagulant clinics for routine monitoring Providing rewards to patients who show perfect compliance with their medication regimen Better information available to patients about what they should or should not do Patient self testing their blood for INR level Nurses or other health-care professionals providing ongoing disease management for patients Pharmacist spending more time educating and counseling patients Improve the speed and accuracy of blood testing Improving communication about blood results – consistent feedback loop, regardless of whether INR results are good or bad Physicians spending more time with patients to provide counseling and support

Somewhat Effective %

16 19 1 30 6 27 13 14 13

Not at all effective %

9 16 14 13 10 9 4 3 2 Q620 How effective do you think the following approaches to increasing patient oral anticoagulant compliance would be? Base: Qualified Respondents (n=101)

Net 1/2 % 25 35 15 43 16 36 17 17 16

45

Chart 16: Written communication is seen by many physicians as a good method of relaying information.

Give written guidelines/handouts Regular counseling/checkups Keep doctor informed about any changes/problems Clearly state goals/risks of taking anticoagulant Watch the diet Check with physician before taking other medications or OTCs Regular blood tests Take medication as directed Help them understand INR test results Face-to-face communication Raise awareness of bleeding Done by hospital/clinic Other Nothing Don’t know/ not sure

5% 5% 4% 4% 7% 12% 11% 14% 10% 9% 9% 18% 18% 3% 25% Q705 Please specify any particularly good methods you use or are aware of to communicate to your patients the “rules and guidelines” they should follow because they are on an oral anticoagulant therapy.

Base: All respondents (n=101) 46

Chart 17a: Physicians trust clinic staff at anticoagulant clinics and different doctors in their own offices the most to help in the management of their anticoagulant patients.

Dedicated oral anticoagulation clinic staff A different doctor (in my office) The nurse or other health-care professional in my office My patient’s other doctors (not in my office) Registered dietician My patients’ pharmacists Technicians at the lab A paid caregiver (such as a nurse’s aid or home-health worker) An unpaid caregiver (such as a family member of the patient)

Trust a Great Deal % Trust Completely %

42 41 52 38 14 26 21 21 19 33 30 20 9 7 6 3 2 1

Net %

74 70 72 47 21 32 24 23 20 Q710 How much would you trust each of the following to help your patients manage their anticoagulant regimen?

Base: All respondents (n=426) 47

Chart 17b: Physicians trust laboratory technicians the least to help them manage their anticoagulant patients.

Technicians at the lab A paid caregiver (such as a nurse’s aid or home-health worker) Registered dietician An unpaid caregiver (such as a family member of the patient) My patients’ pharmacists The nurse or other health-care professional in my office My patient’s other doctors (not in my office) A different doctor (in my office) Dedicated oral anticoagulation clinic staff

Trust Very Little % Do Not Trust at All %

32 17 22 27 20 2 11 2 3 14 9 7 2 1 1 6 5 Q710 How much would you trust each of the following to help your patients manage their anticoagulant regimen?

Base: All respondents (n=426)

Net % 46 26 29 33 25 4 12 3 3

48

Respondent Profile

49

Physician Profile

Total Number of Respondents = 101

Age

20-30 31-40 41-50 51-60 61-70 70+

MEAN Specialty

Family Practice (FP) Internal Medicine (IM) General Medicine Cardiovascular Diseases Geriatrics FP Geriatrics IM

%

1 24 34 35 7 *

45 %

27 27 11 11 10 15

Practice Type

Solo practice Single-specialty partnership/group Multi-specialty partnership/group

Gender

Male Female

Number of Years in Practice

1- 5 years 6- 10 years 11- 15 years 16- 20 years 21- 25 years 26- 30 years 31- 40 years 41- 50 years

%

29 36 35

%

8 23 16 29 15 5 4 1

%

84 16 50