Transcript Document
National Fertility Study 2006 Australians’ Experience and Knowledge of Fertility Issues Dr Anne Clark, MPS, MBChB, FRCOG, FRANZCOG, CREI Chair, Preservation of Fertility Why Do This Study? Australia’s fertility rate (1.81 babies per woman) is below population replacement level (2.1) but “it’s not for lack of wanting kids” * Therefore very important that couples have access to information that enables them to have children quickly and easily when they are ready. Until there is good quality evidence, programs and practice can only be opinion based. * Fertility Decision Making Project, 2004 Methodology • 2400 Australians aged 18 and over • Omnibus survey carried out with equal numbers of men and women • Call backs and appointments used to ensure people who spend a lot of time away from home were included • Results weighted to Australian Bureau of Statistics data on age, gender, locality and level of schooling 300 300 400 700 Sample from 2,400 Australians 600 100 What Makes This Study Unique? The first time an entire country’s adult population has been sampled in relation to its knowledge and experience of fertility issues. The other major Australian study on fertility issues, the Fertility Decision Making Project 2004 (FDMP), commissioned by the Office for Women, published by the Australian Institute of Family Studies surveyed over 3,200 respondents (men and women) but only between the ages of 20 to 39 years about parenting choices and barriers. Results: Ages and Percentage With Children of Those Surveyed 30% Total % Who Have Children 25% 20% 15% 10% 5% 0% 18-19 20-29 30-39 40-49 50-59 60+ Results: Of the 68% that had children, 4 out of 5 did not want any more (81% of men and 31% of women) Of the 32% that had no children, 1 in 2 never wanted children (21% of men and 14% of women) Results: There were no significant differences in results between different states or rural and urban areas. 400 300 300 will only be split by Presentation of results age and gender when a difference occurs 700 600 100 Is Infertility a Modern Issue? No! Those That Took More Than 12 Months to Conceive a Planned Pregnancy Shown as a Percentage of Current Age Group 20% 18% 16% 14% First Child Second Child Third Child 12% 10% 8% 6% 4% 2% 0% 30-39 year olds 40-49 year olds 50-59 year olds 60+ 1 in 6 couples affected consistently from aged 20 onwards. This represents over 3 million Australians But … The Time for Couples to Conceive has Significantly Reduced !! Due to the later timing of events in people’s lives which generally lead to family formation. 10 million Median age of women marrying 1979 2002 1 million Number of eggs available 100,000 1999 10,000 1,000 10 20 30 40 20 years later over 54% of men and 40% of women of the same age were still living at home 50 Age MJ Faddy et al, Mol Cell Endocrinol, 163:43-48, 2000 Australian Bureau of Statistics data Survey Results: Percentage of Sample Who Had Their First Child Under the Age of 30 Women Men 92% 75% 27% 20% 1976 2006 1 in 4 unplanned 1 in 2 unplanned Results: Percentage Who had Unplanned First Children and Treatments for STI 46% 22% 28% 26% 26% Age 20-29 30-39 40-49 50-59 60+ STI 7% 5% 5% 2% 2% 8% of IVF cycles in 2003 for tubal disease cf 28% in 1994 Barriers to Conception: Pre-requisites for Having Children Rated as Very Relevant Stable relationship Good income Partner not ever wanting children M = 26% Your age F = 38% Owning a home Own career You not wanting children ever M = 19% Partner's career F = 34% Your partner's age 0% 10% 20% 30% 40% 50% 60% 70% Two, then three was the most preferred family size 80% Barriers to Conception: Pre-requisites for Having Children Fertility Decision Making Project, 2004 Men Women Rank Rank Afford to support child Partner make a good parent Male partner make a good parent Having someone to love Male partner’s job security Female partner’s age Add purpose/meaning to life Male partner’s age Male partner established in job Giving child(ren) a brother/sister Female partner’s job security Child would be good for relationship Ability to buy/renovate/move home Female partner established in career 1 1 3 4 5 6 8 9 10 11 14 15 15 19 1 3 2 7 4 5 11 9 13 13 12 19 17 13 Two, then three was the most preferred family size Barriers to Conception: Pre-requisites for Having Children 1 in 3 women in their late 20’s and 30’s have no partner … Sydney Morning Herald, 2002 Barriers to Conception: Lack of understanding of the effects of age on a woman’s fertility Dunson et al, Hum Reproduction 2002: 17: 1399-4033 51% of childless women aged 30-49 years thought they could still conceive whenever they wanted to. Despite, 95% also believing their fertility declined with age Barriers to Conception: Marked lack of understanding of the effects of age on a man’s fertility Only 2% thought male factor was a reason to have IVF Actually the single largest reason for Australian couples to have IVF 24% of treatment cycles for male factor alone* Not one person in the study thought a man’s age was a factor in requiring to do IVF 34% of IVF cycles are for men over the age of 40* *AIHW National Perinatal Statistics Unit Data 2003 Barriers to Conception: Lack of understanding of the effects of age on a man’s fertility Impact of male age on chance of natural conception Dunson et al, Hum Reproduction 2002: 17: 1399-4033 Only 20% of women have a younger partner - ABS Only 4 out of 100 women believed their partner’s fertility could affect their chance of conceiving Barriers to Conception: Think they would be able to have a child without any problems Age Women Men 18-19 20-29 30-39 40-49 50-59 60+ 94% 84% 57% 43% NA NA 94% 83% 88% 81% 63% 38% Total: 62% 79% But, only 18% of women and 7% of men didn’t understand that their fertility declines with age How Has Medicine Invested In Research on the Impact of Ageing on Fertility Rates ? Publications found on literature search Impact of increasing female age on fertility Impact of increasing male age on fertility 981 10 1st paper published circa 1952 1st paper published 1982 (30 years later) Barriers to Conception: Lack of knowledge of lifestyle effects - Smoking Active and passive smoking harms sexual and reproductive health throughout reproductive life in both men and women, compromising the ability to have children. Smoking more and for longer increases the risk. “Smoking and reproductive life” British Medical Association, 2004 A child born to a male smoker is 4 times more likely to develop cancer in childhood Barriers to Conception: Lack of knowledge of lifestyle effects - Smoking Despite all of this • 39% of women and 36% of men experiencing fertility problems also smoked. • The impact of passive smoking is not included. • The DNA damage smoking induces in sperm and its abhorrent repair in the fertilised egg can result in embryo mutations that induce miscarriage or impair the health and fertility of the child. J Aitken et al, MJA: 185: 8: 2006 70% 60% Men 50% 40% Women 30% 20% 10% 0% Percentage of smokers by age Under 20 20-29 30-39 40-49 50-59 60+ Barriers to Conception: Lack of knowledge of lifestyle effects - Alcohol Moderate alcohol intake (1 to 5 drinks per week) increases the risk of: - Fertility problems and miscarriage in women - Fertility problems and sperm DNA fragmentation in men Survey shows that 30% of men and 19% of women affected by fertility problems reported they drank more than two alcoholic drinks per day (14+ drinks per week) Barriers to Conception: Lack of knowledge of lifestyle effects: Perceptions of Being Overweight Usual Age at Conception 100 90 Only half the expected number of men surveyed in all age groups reported they were overweight. % with BMI > 25 80 70 60 50 40 30 Men 20 Women 10 0 18-19 25-29 35-39 45-49 55-59 65-59 75-79 20-24 30-34 40-44 50-54 60-64 70-74 80+ Age Group in Years Donath, S.M., MJA 2000; 172: 375-377 – ABS Data People underestimate their “overweight” compared to medical definitions Barriers to Conception: Lack of knowledge of lifestyle effects – Increased Weight Overweight women have an of fertility problems (2 to 5 fold increase) of miscarriage rate (2 to 3 fold increase) success with fertility treatment Weight loss of 5% to 10% dramatically improves pregnancy and outcome rates. Overweight men have an of fertility problems (2 fold increase) and erectile dysfunction (3 fold increase) 9 kilo weight is sufficient to lower fertility rates 42% of men and 52% of women surveyed with fertility problems said they were overweight. Barriers to Conception: Inadequate diagnosis of medical problems that affect fertility: Polycystic Ovaries Polycystic ovaries is a medical condition that affects 1 in 5 women. It has health implications throughout a woman’s life. Age in Years Diagnosis 20 30 40 50 60 70 Infertility Endometrial Cancer Diabetes Ovarian cancer Hypertension Cardiovascular Disease Family members are also at increased risk Lobo R; MJA, Vol. 174, June 2001, p554 Barriers to Conception Inadequate diagnosis of medical problems that affect fertility: Polycystic Ovaries 20% Incidence of PCO Diagnosed PCO 5% Australian research has shown it takes 48 months on average for a woman to be diagnosed with polycystic ovaries and its complications from the time of first presentation to a medical practitioner Barriers to Conception Inadequate diagnosis of medical problems that affect fertility: Endometriosis Incidence of Endometriosis Diagnosed Endometriosis 10-15% 7% Incidence of Endometriosis in fertility patients Diagnosed fertility patients 30-40% 12% Genes that effect inheritance have been identified. Other women in the family effected could also miss early diagnosis. Diagnosis takes 8 to 11 years on average. Endometriosis is a condition associated with pain, infertility and menstrual problems in which the cells that line the uterus grow outside it. What Proportion of Those Surveyed Indicated a Concern About Fertility Preservation? 86% of women surveyed had or wished to have children but Only 9% expressed concern about fertility preservation, principally women in their 30’s and 40’s How Has Medicine Invested in Research on Reproductive Education Publications found on literature search 99:1 Ratio Patient education Patient education Contraception Fertility preservation 13,596 148 45% related to STD’s, 23% post cancer and other medical conditions If People Have Fertility Problems, Who do They ask for Advice ? Men Women Family 54% 65% Friends 44% 61% Natural therapist 34% 48% Won’t see a Doctor 14% 10% Change lifestyle 59% 74% But 59% of those with fertility problems have never consulted a doctor! Conclusions: Fertility problems are common, affecting 1 in 6 couples They affect over 3 million Australians 400 300 300 Fertility problems also impact on the couple’s extended family 700 Fertility problems are associated 600 with long term health issues 100 Conclusions: ‘It takes two to tango’ Fertility is a couple issue not a woman’s issue Socially – Medically - Personally Conclusions: Societal changes have impacted significantly on couples. Lifetime events are happening later so a couple might not be able to have children until the time their fertility has already started to decline Finally: Australians badly need more information to make the right choices. They also need a National Fertility Policy to enable all interested groups including government to coordinate their efforts and resources 400 300 of Australia 300 • Fertility Society • ACCESS Australia • Australian Medical Association • Andrology Australia 700 • Australian Reproductive Health Alliance • Indigenous Australians Sexual Health Committee • Jean Hailes Foundation 600 • Polycystic Ovarian Syndrome Association of Australia • Royal Australian College of General Practitioners 100 • Royal Australian & NZ College of Obstetricians & Gynaecologists • Sexual Health and Family Planning Australia Moving towards a National Fertility Policy Action to date: • Community survey commissioned • GP survey commissioned • FSA presentation to Parliamentary Support Group on Fertility Preservation & partners • FSA presentation to bipartisan Parliamentary Group on Population & Development • FSA meeting with RACGP National Standing Committee for Quality Care • FSA to host Fertility Information Day with Parliamentarians and partners, Canberra • Prepare program for Government Funding • FSA Conference - Fertility Preservation August 2006 September 2006 11th October 2006 18th October 2006 In 2 weeks 28th Nov 2006 February 2007 September 2007 Acknowledgements • Fertility Society of Australia • Preservation of Fertility Team • Anne Clark - Chair400 300Pope 300 • Adrianne • Sandra Dill • Devora Lieberman 700 • Michael Chapman 600 • Nicole Phillips • Labett Research 100 1000