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Starting Up and Running Health
Enterprise East Ltd
A Case Study of a Limited Company
Operating inside the National Health
Service – and a Historical Perspective
Masterclass March 12th 2010
Professor Alan Barrell
Chairman – Health Enterprise East Ltd
1
A Preview
 The Nations Health and the NHS- Dilemmas and
Challenges
 Health Services in the East of England
 A bit of history – healthcare Innovation is NOT easy !
 Creativity and Innovation
 Enterprise, Entrepreneurship and Enterprise Hubs
 Health Enterprise East Ltd – Start Up, Progress and plans
 Discussion and Debate
2
Chairman of Health Enterprise
East, also wearing other hats
Chairman – NHS
Regional Innovation
Council
3
Does our “Eye on the World” see much
change?.... Our context….
4
More
Healthcare
– Reduced
Budgets
Dilemma –
Population
and Ageing
Innovation is Essential
5
6
Crisis ?.......or Opportunity?
危机
Creativity and Innovation beat Despair
any day! Call to action for
Entrepreneurs
What we have PLEDGED in Healthcare for the
East of England - MISSION
A better patient experience
We will deliver year on
year improvements in
patient experience
We will extend access
guarantees to more of
our services
We will ensure that GP
practices improve access
and become more
responsive to the needs
of all patients
We will ensure that NHS
primary dental services
are available locally to
all who need them
Improving people’s health
We will ensure fewer people
suffer from, or die
prematurely from, heart
disease, stroke and cancer
We will make our health
service the safest in
England
We will improve the lives of
those with long term
conditions
Reducing unfairness in health
Working with our partners,
we will reduce the
differences in life expectancy
between the poorest 20% of
our communities and
average in each PCT
We will ensure healthcare is
as available to marginalised
groups and looked after
children as it is to the rest of
us
We will cut the number of
smokers by 140,000
We will halt the rise in obesity
in children and then seek
8 to
reduce it
The Ten Programme Boards
• Staying Healthy
• Mental Health
• Maternity and Newborn
• Children's’ health
• Planned Care
• Acute Care
• Long Term Conditions
• Palliative and end of life care
• Patient safety
• Patient and carer experience
A new focus on our vision
Quality
Innovation
Engagement
Analysis
Ideas
Leadership and
Talent
Productivity
Prevention
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Regional Innovation Fund £1.94M in
2009/10
Long term conditions - priority for our QIPP
agenda
 2009/10 RIF focused on Long Term
Conditions innovations
Emerging priority areas:
Patient engagement and co-production
Personal health plans
Supported self care
Commissioning integrated pathways
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Compact with industry
 Two way communications
Set out vision and needs of NHS
Learn about range of products and devices
 Translating NHS Long Term Conditions needs to
industry
 ‘Founder member’ of Cambridge Network
healthcare special interest group
 Sponsored ‘ Partnership with NHS’ award from
Eastern Region Biotech Initiative
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From a great man – Polymath – 600 years
ago…. Starting our sense of History….
Our
challenges
in context
Is all this
anything
new ?
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He gave us
beauty as
well as
science
A Giant
amongst
men….
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Leonardo….
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Leornado Da Vinci….
But the History of
Medicine and
Great Discoveries
goes back much
further….
Chinese and
Egyptian
Discoveries and
Practices have
survived until
today
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Great Innovations can meet even
greater opposition
Ignatz Philip
Wash hands
Semmelweis
Classical work
1847
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Adoption of the Semmelweiss Innovation – still not there TODAY !
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Streptococcus pyogenes
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“Chance favours only the prepared
mind”
Bacteria
Louis
Pasteur
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Joseph Lister and Antisepsis
Transformational work….Revolutionised
potential for Surgery and Medicine
generally
1. Anaesthetics – Horace Wells
2. Antibiotics –
Alexander Fleming
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What Alexander Fleming might have seen in 1928….and what
doctors and technicians still see today….
Remember Louis
Pasteur’s
assertion –
“Chance favours
only the prepared
mind….”
A “failed”
experiment – led to
the discovery and
development of
Penicillin – and
many more
antibiotics….
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Innovators and
Entrepreneurs
have often been
great improvisers
From old
washing
machines and
car parts to….
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Willem Kolff’s first Drum Kidney Machine - 1942
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Innovation is a
journey – not a
destination….
From drum
to coil….and
it goes on..
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Sir Frederick Banting – Nobel Laureate –
From Canada
Diabetes –
major killer
INSULIN ! He
was 21 when he
made the
discovery !
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Three Converging Revolutions
Three Pervasive Technology Platforms – looking at Diverse Science
and Innovation and how Science can become Products and Practice
BioTech
Pharmaceuticals
Diagnostics
Research/Info
Tools
Industrial
INFO TECH
Hardware
Software
Communications
Genomics
Bioinformatics
Proteomics
Bioelectronics
Microfluidics
Nanobiotechnology
Drug Delivery
Biosensors
Biochips
Nanodevices
Nanosensors
Nanoelectronics
NANO TECH
Electrical
Structural
Biomedical
Energy & Environment
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Closeness of Learning, Research and
Practical Application
“The Innovation Campus” – Cambridge is one BIG Innovation Campus !
R&D
Education
Applications
Where open innovation, symbiosis, synergy and new
companies can thrive
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Converging Technologies in
MedTech
BioTech
I.C.T.
Medical
Technology
Engineering
Advanced
Manufacturing
Electronics
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Charactersitics of Regions planning to be Leaders in Sustainable
Technological Development – including in Medical Sciences
nt ers
 Entrepreneurs & Role Models
Lif e
Know
ledg
e ce
f
ity o
Qual
Go
ve
rn
 Knowledge Centers
me
nt
eu
en
E
rs
r
ep
r
t
n
 Capital Markets
 Infrastructure
Role Models
Ne tworks
 Money
 Cluster Policy
 Presence of International
Companies
es
Ci
l
na
Mone
y
ic
y
ol
lM
it a
 Quality of Life
ts
ke
ar
Infrastructure
Cl
us
te
rP
 Networks
 Government
p
Ca
t io
na
r
e
Int
Minds without Borders – Global
Mindset
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From Idea to Reality – A New Enterprise - Free
Standing – or in a Corporate Structure….
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MedTech – from Idea, to Innovation to
Reality – needs Patient Capital ….
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Some Destinations on the Journey
Put your own timescale in….and - imagine costs….££££
 Ideas
 Plans
 Designs
 Regulations
 Multi-skilled teams
 More Plans and Approvals
 Prototyping and Validation
 Manufacturing and Final Testing
 Clinical Acceptance and Validation
 Marketing and into use….REALITY!
 Revenues, Profits, Returns, Patient Benefits
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Incubation and Implementation –
MedTech – a world of….complexity
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But the Commercial Markets are BIG………and
growing….
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Medical Companies, like all others, that fall behind and don’t compete may
not survive….Competition encourages Investment in Innovation
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The Internet has REVOLUTIONISED Product Development and
Innovation in many areas – including Healthcare
Innovation happens mostly with USERS not SUPPLIERS
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And then….we
have the Wireless
Connection
Revolution
Will you have
“Your GP in
your Handset in
the future ?”
44
Visions of the future A Multidisciplinary Company
Integrated Technical Skill Base
ENGINEERING
ELECTRONICS &
COMMUNICATIONS
CHEMISTRY & MATERIALS
MICROFABRICATION
LIFE SCIENCES
OPTICS, ACOUSTICS & PHOTONICS
45
An example already there today - Philips is present across the entire care cycle
- extending healthcare from the hospital to the home-and moved its R & D to
Cambridge in 2008
Intensive Care unit
Monitoring
Operating room
Monitoring
Imaging
Treatment
Consumer
Healthcare
Solutions
Treatment
Diagnostics
Diagnostics
Diagnosis
Prevention
Personal
Healthcare
Rehabilitation
Management
Remote
monitoring
Diagnostics
Imaging
Follow Up
Pre-Hospital/Ambulance
Monitoring
Emergency
Response
Services
“The array of health services and care settings that address health promotion, disease prevention, and the diagnosis, treatment,
management, and rehabilitation of a disease, injury, and/or disability.”
Center for Disease Control and Prevention (CDC), US Government`
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How about some IMAGINATION ? – It seems
necessary….
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Einstein on IMAGINATION….
“Imagination is more important than
knowledge. Knowledge is limited.
Imagination encircles the world”
Albert Einstein 1879 - 1955
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Opportunities for Entrepreneurs Healthcare needs them !
“You look at things
and ask - why?
but I dream of things
that never were and
ask why not?”
George Bernard Shaw
A matter of MINDSET
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Against this history and background ….Health Enterprise East Ltd
– facing the Challenges of Implementing Innovation – looking
for more innovators and heroes
An NHS Innovation Hub part
of the national NHS
Innovations Network
A not for profit company
limited by guarantee
Five years old and going strong
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A TOP TEAM – Ready and Willing to help YOU realise Opportunities
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Health Enterprise East – Founded
2005
We provide advice, support and
resources to turn the ideas of NHS
staff into new products and services
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Health Enterprise East
Helps NHS staff to identify and evaluate
innovative new ideas
Provides funding for filing of patents,
designs rights & other registerable IP
Development funding available to
progress new ideas
Negotiates commercial deals on behalf of
staff and their Trusts
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Annual Innovation Competition
 Open to all NHS staff in the
Region
 5 categories: Medical Technology
 Software, IT and Computers
 Infection control
 Prevention & wellbeing
 Publication & training aids
 Celebratory Awards Dinner
 £20k prize money
 Sponsored by companies
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Medtech Services – Helping Company Access
and Getting Innovative Systems Evaluated –
“Opening Doors”
Help companies access NHS
expertise
Source of revenue for NHS
staff
Expose NHS staff to the latest
technological innovations
Industry Experts and IT and
Software Executives in Team
Dr Juan Roman, HEE
Medtech Services Manager
55
Working together to PUT Innovative Products
and Services to work – Some Issues for us all
Balancing Process and Safety with Innovation
Finding and Exploiting Innovation – Barriers
Adoption and Diffusion
The “Top Down” – “Bottom Up” Dilemmas
The Minefield of Regulatory Standards and
Harmonisation in the EC.
Leadership and Creating an Innovative Mindset
Care “Everywhere” – Home, Community,
Hospital, Work – and need for connectivity
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In Pursuit of Excellence !
“Excellence can be achieved, if we:
Care more than others think is wise,
Risk more than others think is safe,
Dream more than others think is practical,
Expect more than others think is possible.”
Deborah Johnson-Ross
Excellence in Medicine and Medical Technology is everyone’s
dream and in the West our expectation
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