Transcript Document

New Technology
To treat Prostatitis
The Prostate
Heat can be used for
medical purposes
…”Already at the beginning of the 19th
century first clinical trials with systemically
induced fever were performed on malignant
tumors”…..
Hyperthermia in cancer research.
Historical development, current status of research, future perspectives
and differentiation from alternative medical procedures.
Issels R, Wadepohl M, Cramer H, Krieger K, Wilmanns W.
Effect of temperature on
living tissues
Effects of temperature
Normal Ramge
Hyperthermia
Termotherapy
33º C to 37º C
37º C to 43.5º C
45º C to 99º C COAGULATION
Vaporization 100º C and more ABLATION
Cell kill by heat
Termotherapy :Efects of
Temperature on tissues
Temperature above 45º C produces
Coagulative Necrosis
Denaturization of proteins.
Immediate cell kill
Harnessing RF Waves for Treatment
RF is a safe and effective treatment for many medical
conditions, used routinely for surgical procedures.
RF energy in contact with tissue will produce heating
and therefore its coagulation or vaporization.
Range used for medical applications
is between 100kHz and 1200MHz
RF Waves
The Nervous system system operates at low Frequency
Low Frequency signal cause : muscle contractions  Pain
Large Dose  Cardiac Arrest
Heating Methods
T.U.M.T. Microwave (Cooled)
T.U.M.T. Microwave Un-cooled
W.I.T. Water Induced Thermotherapy
T.U.R.F. AND T.U.N.A.
Monopolar Radio Frequency
TEMPRO
Bipolar Radio Frequency
Heat can be applied to PROSTATE by 2 technologies
Microwaves : T.U.M.T. =Trans Urethral Microwave Thermotherapy
Radiofrequency: T.U.R.F. =Trans Urethral Radio Frequency
Non uniform distribution of energy using microwaves TUMT
Uniform distribution of Radio Frequency heating
Tempro
Bi-Polar RF
Thermotherapy
The device that applies the Radio
Frequency energy in Tempro


The Applicator is a unique transurethral multi-polar
electrode with conductive heating rings and
temperature sensing elements (thermocouples)
The applicator diameter is 16Fr. (about 5.5mm)
Heating
Rings
Bladder
Drainage
Opening
3 Thermocouples
Balloon for Applicator’s
Positioning
Functions of the Applicator
Delivers RF energy from the controller to
the prostate, producing tissue
coagulation.
Measures prostate temperature at 3
different locations.
Allows urine to be drained during
treatment.
Testimonios
Amstelland Hospital Holanda
Amstelland Hospital
Dept. of Urology Men’s Health Clinic
Y. Reisman MD, PhD
Laan vd Helende Meesters 8,
1186AM, Amstelveen, Noord-Holland,
The Netherlands
Telephone number: +31-(0)20- 3474747
I have started to use the Tempro system for BPH , but later on
decided to use Tempro Thermal Therapy also for Chronical
Prostatitis , which as we all know is very difficult to treat . The
initial results with several of my patients are very positive and it
appears to be a very helpful procedure “. Dr. Y. Reisman
Age: 35
Chronic Abacterial Prostatitis from date: 04-01-2008
Previous treatments: NSAID, Ciproxin, Tamsulosine
Symptoms: Perineal pain, sexual dysfunction, LUTS
Tempro treatment date: October, 2008.
Follow up: 12 month free of complains
Testimonios
The Institute for Thermotherapy- Alemania
The Institute for Thermotherapy
Dr. C. Beck
Kleppingstrase 8,
44135 Dortmund
Telephone: +49 231 14 12 88
Germany
One of my patients could hardly stand up straight even though he was taking prescription
drugs. After a Thermal Therapy treatment with Tempro Device he began to notice relief and
he felt no pain at all."Dr. Christian Beck
Age: 32 Chronic Abacterial Prostatitis from date: 15-10-2003
Previous treatments: NSAID, Ciproxin, Tamsulosine
Symptoms: Perinea pain, sexual dysfunction, LUTS
Tempro treatment date: January, 2009.
Follow up: 9 month free of complains
Testimonios
Private Medical Clinic and Laboratory-Polonia
Private Medical Clinic and Laboratory
Dr Zenon Rudzki
Kilinskiego St 78
Tel: + 48 34 365 1404
Czestochowa
Poland
“I have always thought Thermal Treatment may benefit my Prostatitis patients. Now that I
have started to use the Tempro for Chronical Abacterial Prostatitis. I am surprised by the
excellent results with some of the initial patients I have treated “. Dr. Z. Rudzki
Age: 65
Chronic Abacterial Prostatitis from date: 03-10-1999
Previous treatments: NSAID, Ciproxin, Tamsulosine
Symptoms: Pain in Testicles, Pubic area, Bladder, tip of Penis.
Tempro treatment date: December, 2008.
Follow up: 10 month free of pain or discomfort, Free urination
TEMPRO Bipolar Radio Frequency Thermal Treatment
FOR ABACTERIAL CHRONIC PROSTATITIS : Initial results
Byun, Jae Sang MD, , Byoung Kyu Han MD, Kihyuck Moon MD
Gangman Zaii urology Hospital.
Nonhyeon-dong 164-2 Seoul
Republic of Korea
Table 1. Patients demographics
Characteristics
Value
Numbers of the patients
41
Mean age (range)
42.6 ± 11.4 (28 – 72)
Mean prostate size (cc)
25.3 ± 6.1
NIH classification (%)
Category II
13 (31.8%)
Category IIIA
14 (34.1%)
Category IIIB
14 (34.1%)
Table 2. Comparison of Chronic Prostatitis Symptom index scores
between pretreatment (baseline) and TEMPRO after 3 months (post TEMPRO) CPSI score
Baseline CPSI
score
Post-TEMPRO p
CPSI score
value
Mean Total score
23.4 ± 7.3
16.5 ± 4.9
0.072
Mean pain domain score
11.2 ± 5.4
6.5 ± 3.8
0.034
Mean Urination domain score
5.7 ± 3.3
5.2 ± 2.3
0.872
Mean Quality of life domain
score
6.6 ± 2.4
4.6 ± 1.6
0.138
Table 3. Subgroup analysis according to the decline of CPSI score more than
50 percent at 3 month after TEMPRO.
Group A : CPSI scores decreased more than 50% after TEMPRO
(= successful group)
Group B : CPSI scores does not decreased more than 50% after TEMPRO
(= unsuccessful group)
Group A
Group B
19
( 46 % )
22
( 54 %)
50 or Younger
than 50 years old
12
17
Older than 50
years old
7
5
Category II
8
5
Category IIIA
9
5
Category IIIB
2
12
Total Success
p value
Age group
0.638
NIH classification (%)
0.052
4.Conclusions
These initial results look very positive with an overall success rate of 46 %.
Perineal and/or perianal pain, as well as orchalgia, are substantially
improved in the majority
of the patients.
Considering the complexity of the illness we consider it a simple and effective treatment.
Side effects are minimal, therefore the Tempro treatment for prostatitis
should be considered as a safe and effective one.
We will continue to explore the potential of this treatment.
Congreso Mundial de Endourologia WCE 2009 Munich Octubre 2009
Congreso Mundial de Endourologia WCE 2009 Munich Octubre 2009
Congreso Mundial de Endourologia WCE 2009 Munich Octubre 2009
Congreso Mundial de Endourologia WCE 2009 Munich Octubre 2009
Maneken Pis
Thank you very much for your
presence on this meeting
Direx Group