Transcript Document

Where Science Means Business
An Introduction to Yissum
November 2007
Tami Kfir, VP Licensing Healthcare
0
The Hebrew University Of Jerusalem
4 Campuses
320 Researchers
in Applied Sciences
1,600 Post-Graduate
Students in Biotechnology
5 Affiliated Hospitals
1,200 Researchers
(Staff Members)
24,000 Students
Over 1/3 of all academic scientific
research In Israel
43% of Israel’s biotechnology research
>1/3 of PhD students in Israel
1
The Hebrew University of Jerusalem
Mount Scopus Campus, Jerusalem
2
The Hebrew University of Jerusalem
Agriculture & Environmental
Sciences Campus, Rehovot
Edmond J. Safra Campus,
Jerusalem
3
The Hebrew University of Jerusalem
Ein Kerem Campus, Jerusalem
4
Israel’s Top University
 U of Texas for Institute of Higher
Education, Shanghai Jiaotong University
 Israel 12th worldwide in academic
research
 Hebrew University no. 1 in Israel
 60th worldwide
 Only Israeli university in top 100
 Times Higher Education 2006
 HU 63rd worldwide in biomedicine
 HU 52nd worldwide in science
 29th worldwide ex-US, UK
 Newsweek
 Hebrew University 82nd worldwide
 Only Israeli university in top 100
5
A Nobel Heritage
 2002 Nobel Prize in Economics
 Daniel Kahneman, Princeton
 2004 Nobel Prize in Physics
 David J. Gross, UC Santa Barbara
 2004 Nobel Prize in Chemistry
 Avram Hershko, Technion
 Aaron Ciechanover, Technion
 2005 Nobel Prize in Economics
 Robert J. Aumann, Hebrew University
 2006 Nobel Prize in Chemistry
 Roger Kornberg, Stanford
6
7
Top 20 Most Frequently Cited Papers
Stem Cells 1998-2004
8
9
http://www.milkeninstitute.org/pdf/m2m2006_uni_bio.pdf
A Broad Range of Technologies
Medicine
Materials
Biotech
Nanoscience
Agriculture
Computer
Sciences
Homeland
Security
10
Computer
Engineering
Environment
Yissum’s Mission
To promote the transfer of Hebrew
University technology for the benefit of
society, while maximizing returns to
support research, education and
scientific excellence
11
Current Snapshot
 $1 Billion annual sales of Hebrew University



based products
5,000 patents
1,400 inventions
400 licenses
60 spin-offs
 Raised $150 mil in past year from leading VCs
12
A Record of Achievement
 2006 revenues $40mil, up from $34mil in 2005
 $29mil royalties
 $11mil sponsored research & services
 HU research budget $100mil
 Ranked in top 15 worldwide (AUTM)
 Leading US university royalties
 MIT $35-40mil / year
 Research budget: $1 Billion
 Stanford $50-60 / year
 Research budget: $900 Million
13
Where Science Means Business
The Hebrew
University
Non-profit
organization
Board of
Directors
Business leaders
Yissum
Business-oriented
organization
Founded 1964
14
Board of Directors
Giora Yaron, PhD – Chairman
Uri Banin, PhD
Reuven Behar
Hervé Bercovier, PhD
S. Morry Blumenfeld, PhD
Martin Gerstel
Elhanan Hacohen
Alex Keynan, PhD
Amos Mar-Haim
Hadar Ron, MD
Moshe Vigdor
Chairman, Mercury; founder, P-Cube, Exanet
Hebrew University, Director Nanoscience Centre
Managing Partner, FBC&Co.; chairman, Netafim
Hebrew University, VP R&D
VC, ex-CEO GE Medical, Israel
Ex-CEO Alza; chairman, Compugen
Hebrew University, VP & Director General
Hebrew University, Prof. Emeritus
Director, JDA; Ex-CEO Clal Industries
Managing Director, Israel Healthcare Ventures
Director General, Jewish Agency
The Challenge
Industry
vs.
Product-based
Business-oriented
Mission/project focused
Confidentiality essential
Timeframes & milestones
Economic role
16
Academia
Knowledge-based
Curiosity-driven
Broad scope
Publications
No time limits
Educational role
Intellectual Property
2006 Snapshot
 100 new inventions
 72 new patent applications
 58 new patents granted
2006 New Inventions
Agriculture
6%
Materials
13%
Intellectual Property at HU
 Yissum owns all IP
developed at HU
 Researchers receive
40-60% of revenues
Applied Physics
2%
Business Models
Computer Science &
1%
Engeneering
13%
Environment
2%
Food and Nutrition
2%
Life Science and
Biotechnology
61%
17
Global Reach
18
Yissum’s Spin-offs
Rav-Galai
19
Success Stories - Tomatoes
Long Shelf Life & Cherry
Tomatoes
The world’s most popular
cocktail hybrids for
greenhouse production
Prof. Nachum Kedar
Prof. Haim Rabinowich
Department of Field Crops,
Vegetables and Genetics:
Faculty of Agriculture, Food
And Environmental Sciences
The Hebrew University
Rehovot Campus
2006 sales $70 million
20
21
Success Stories - Doxil
DOXIL®
Doxorubicin HCI liposome injection
Alza’s Lead Product for
Oncology
Prof. Yechezkel Barenholz
Department of Biochemistry
Faculty of Medicine
The Hebrew University
Of Jerusalem
2006 sales $375 million
22
Success Stories - Exelon
For Treatment of Alzheimer’s
Disease and Dementia
Prof. Marta
Weinstock-Rosin
Department of Pharmacology
Faculty of Medicine
The Hebrew University
Of Jerusalem
2006 sales $525 million
23
Healthcare - Source of Innovations
•
•
•
•
•
Faculty of Medicine
School of Pharmacy
School of Dental Medicine
l
Faculty of Science
Faculty of Agriculture
Healthcare Technologies Scope






NCEs
New Uses
Drug Delivery
Medical devices
Diagnostics
Research tools
Markets
•
•
•
•
•
•
•
•
•
CNS
Dermatology
Oncology
Infectious Diseases
Cardiovascular
Respiratory diseases
Metabolic
Dianostic (biomarkers; Imaging,
Bioinformatics)
Devices mainly Therapeutics
World Wide Leaders in Drug Delivery
Main Expertise:
•
•
•
•
•
•
•
Liposomes
Sustained release
Transdermal
Nasal
Colonic Delivery
Biodegradable - Polymer encapsulates
microparticulate and nanoparticulate targetable drug
delivery systems
World Wide Leaders in Drug Delivery















Yechezkel Barenholz
Simon Benita
Daniel Cohen
Abraham Domb
Michael Friedman
Nissim Garti
Chaim Gilon
Gershon Golomb
Avraham Hochberg
Amnon Hoffman
Philip Lazarovici
Shlomo Magdassi
Abraham Rubinstein
Elka Touitou
Itamar Wilner
Bio Park
•
•
•
First in Israel
Service & support from near by university and
hospitals
10,000m2 of research laboratories
Commercial Efforts
 Friendly WebSite
 Use of web – tools such as Pharma –




Licensing
MiniPlans
Israeli Opportunities: Incubators; BioLine;
Teva
Active marketing worldwide including BioConferences
Networking
TTM (Technology Transfer Management)
The TTM can help you manage your entire technology transfer or licensing
office. It can help increase the effectiveness of your office without increasing
size. Some of the benefits using the TTM include:
 Increase the quality of your invention disclosure
 Improve the financial management of your technology portfolio
including connection to an external financial system (SAP)
 Maximize license revenues through effective contract management
 Improve contact with researchers in your organization allowing them
external access to the system.
 Expand marketing reach of your organization for your technologies by
allowing easy export of the technologies to external databases including
the website
 Make powerful reports on the data for effective business management
and follow up
 Integrated with Office environment
 Built with the most up to date technology
Thank you for your attention
[email protected]
32