Transcript FOOD SAFETY MISSION 2008

‫بسم اهلل الرحمن الرحيم‬
Role of QCAP Lab in Control of
Pesticide Residues and Food
Contaminates in Egypt
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Contents
_______________________________
History
 Objectives & Missions
 Lab Facts
 Lab Cooperation & Other Scientific Activities
 Lab Staff &Organizational Structure
 QCAP Lab Scope &Analytical Activities
 Microbiological Examinations
 Analyzable Products
 Accreditation & Technical Scope
 Summary
 Future Plan
_______________________________________________________________

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The Central Laboratory of Residue Analysis of Pesticides
and Heavy Metals in Food (QCAP Lab) was established in
1995, under the Agricultural Research Center (ARC),
Ministry of Agriculture and Land Reclamation of Egypt
(MALR) according to the Ministerial Decree no. 680/1995
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QCAP
The laboratory is the main output of the
collaboration between Egyptian and Finnish
governments through the Quality Control of
Agriculture Products Project (QCAP).
The laboratory is still known as the QCAP Lab.
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QCAP Lab
Objectives & Missions
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Lab Missions
Safe Food…Healthy People

QCAP Lab is focusing on food safety under two major activities;
1- Egyptian Consumer protection against chemical and biological
contaminants in food and environment.
2- Promoting exports from agricultural products through guaranteed
safety standards and measurements that comply with the
requirements of the importing countries.
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Lab Objectives
Control of pesticide residues and food contaminants throughout:
 Analyzing
samples from shipments of agricultural products prior to
export and issuing accredited certificates for results.
 Analyzing
samples from certain imported food & agriculture products in
order to prevent food not complying with the standards of contaminants
to enter the country for consumption.
 Monitoring
status of chemical and biological contamination in food and
agricultural products in the local markets through the National
Monitoring Program in the laboratory.
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Laboratory Activities
Cooperation with:
 Research Institutes
 Export & Import Companies
 Farmers and Consumers
 Organic Agriculture Organization
 National and official organizations such as, Agricultural and Veterinary
Quarantine, General organization for export and import control GOEIC,
General organization of veterinary services, GOVS


Training of inspectors from plant quarantine on the methods of sampling.
Development and renovating of the methods of analysis

QCAP often the early leader in developing analytical methods to fulfill the
international standards and to respond to emerged food crisis.

Provide training on the scope of analytical work.
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Training

Training Programs for:
Trainees
from Arab and African Countries in the Region
Researchers and interested groups
Inspectors of AQ
Growers specially at sampling procedures

Program includes:
Sampling Procedures according to international standards
ISO 17025 and labs accreditation
Quality control and quality assurance system
Analytical methods adopted in the laboratory,

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Lab Facts
 The
Lab is accredited since 1996 and in full
compliance with the general criteria for testing
laboratories laid down according to ISO/IEC
17025:2005 “General requirements for the
competence of calibration and testing
laboratories”.
 More than 14 years of accumulated experience.
 Full service, fully equipped food analysis testing
capabilities.
QCAP LAB HOLDS THE LEADER POSITION IN EGYPT IN
DOMAIN OF ITS WORK.
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Lab Facts
 Highly
trained professional and competent
analysts and microbiologists.
 Running many of scientific researches in the field
of pesticides residue and contaminates in food.
 Analyzing more than 500 contaminates.
 Detection of 15 food-pathogens.
 More than 40 accredited methods of analysis for
chemical and biological pollutants in food.
 The laboratory analyzed more than 320,000
samples since 1995.
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Lab Facts

Reference Center of food residues - contaminates and
environmental pollutants.

Expand scope of analysis to include:
CONTAMINANTS
RESIDUES
Pesticides in fruits and vegetables
Pesticides in animal-food & feed
Veterinary drugs in animal food origin
OTHER TESTS
Food Additives (Flavors, Colorants)
Nitrates
Illegal Dyes (Sudan & Malachite green)
Heavy metals
Mycotoxins
Persistence Organic Pollutants –
Dioxins, PCBs & PAHs
Acrylamide
Melamine & related compounds
Histamine, Ciguatoxins
FOOD PATHOGENS
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Relations Between QCAP Lab &
Other National Organizations
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Lab Staff &
Organizational
Structure
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Lab Staff
Total number of persons employed in the Lab
is 160
The lab is divided into two main activities:
The Chemistry lab (54 analysts),
The Microbiology lab (6 microbiologists)

Approximately one half has completed one of the post graduate studies
abroad or at home (Masters of Science, Doctors of Science).
Others (100) technicians, Supported staff , Secretariats,
financial & administration departments, maintenance
engineers, receptionists & customer service, data handling &
computer services, etc.).

The
prevailing age group among the researchers and
analysts ranges between 25 and 35 years.
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
All lab Staff persons had extensive inhouse training courses discussing:
CAC & EU Directives and Regulations
 Sampling, chemical & microbiological
analyses,
 Quality control and quality assurance
according to ISO 17025:2005.

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


Personnel skills are continually updated through
attendance of training courses, workshops,
professional conferences, and regular
participation in national and international
organizations meetings.
More than 75 missions and training abroad from
2005 up to 2009.
List of scientific publications includes more than
90 research papers & theses.
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Organizational
Structure
LAB
DIRECTOR
- QA Manager
- Technical Managers
Administration
& Accountants
CHEMICAL
LAB
QUALITY
MANAGER
-Technical Manager
-Deputy TM
-Analysts
Pesticide Residues
Heavy Metals
Mycotoxins
Dioxins and Dioxin-like PCBs
Sudan dyes
Nitrates
Chlormephenicol
Veterinary Drugs, others…
MICROBIOLOGY
LAB
Database &
Information
Center
Technical Office
& Training Services
-Technical Manager
- Deputy TM
- Microbiologists
Assisting Personnel
Computerist, Lab. assistants, stock keepers,
sample receptionist, sample transporters,
glassware washers, cleaners, guards, security
persons, and technical engineer.
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QCAP Lab
Scope &
Analytical Activities
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The Lab has a pivotal role in analyzing different
types of chemical and biological contaminants in
food and environment that including:
 More than 500 chemical contaminates analyzed.
 15 food-pathogens Microorganisms detected.
 Standard methods used: AOAC, ISO, CEN.
 Methods validated before use: LOQ, recovery,
linearity, repeatability, reproducibility, accuracy &
uncertainty.
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Pesticide Residues
 More
than 400 compounds from different chemical
Groups using LC-MS/MS and GC-MSD techniques.
 Wide range of pesticides (requested by customers, registered, or
banned). “Mistrial Decree 622/2008”
 Fulfilling the requirements of international standards:


Pesticide EU-MRLs (0.01 mg/kg)“Regulation (EC) No 396/2005”
Codex Alimentarius requirements.
 Investigating
pesticide residues in organic products.
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Pesticide Residues

QCAP participate in EU-CRL PT-FV and classified as
category A

QCAP approved from QS-system Germany,
Quality and Safety of food chain from “Farm to Fork”

QCAP approval from EDEKA markets in Germany

Contracted with food expert -Spain
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Heavy Metals & Trace Elements
Analytical Methods
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
Copper Cu
Lead Pb
Cadmium Cd
Tin Sn
Mercury Hg
Zinc Zn
Iron Fe
Arsenic As
Aluminum Al
Manganese Mn
Chromium Cr
Cobalt Co
Nickel Ni
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Mycotoxins
Mycotoxins



Aflatoxins B1,B2, G1,G2
Ochratoxins
Patulin
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Dioxins and PCB’s like dioxins



Dioxins are stable compounds, the minute amount of it
cause hazards effect on human and environment.
The laboratory introduce the analysis of dioxin although
the difficulties of their analysis. The analysis need
special trained persons, special instrument for
identification of the very small amount of residues
measured in Pico-gram levels.
Dioxins compounds consist of 210 congeners, 17 of them
are the most toxic.
HRGC/HRMSD
for Detection of POPs
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Veterinary Drugs & Antibiotics
Analytical Methods
* Groups defined in Annex I of council directive 96/23/EC
** Compounds included in Annex IV to Council Regulation
(EEC) No 2377/90
Substances/
Status
Compounds
Covered
Group A1
Essential
Diethylstilbestrol, Hexestrol, Dienestrol
Group A3
Essential
Trenbolone, Testosterone, Progesterone
Group A6**
Essential
Chloramphenicol, Dimetridazole, Ronidazole
Group B1
Essential
Amoxicillin, Ampicillin, Ceftiofur, Chlortetracyclin, Ciprofloxacin,
Doxycyclin, Enrofloxacin, Erythromycin, Flumequin, Gentamycin,
Lincomycin, Oxytetracycline, Penicillin V, Sulfa drugs, Tetracycline,
Trimethoprim, Tylosin
*
Group
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Other Specific Analytical Methods
 Benzo(a)pyrene
 Nitrate
 Histamine
 Ciguatoxin
 Melamine
& Analogues
 Illegal Sudan Dyes

Sudan I, Sudan II, Sudan III,
Sudan IV, Sudan Red 7B, and
Sudan Orange G, para red.
 Illegal
Malachite Green
 Acrylamide
 Food Additives
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Microbiological Examinations
( 15 food-pathogen microbes)
1. Bacillus cereus,
2. Clostredium perfringens,
3. Coliforms,
4. Fecal coliforms,
5. E. coli,
6. Enterobacter ,
7. Enterococci,
8. Listeria monocytogens ,
9.
10.
11.
12.
Molds,
Yeasts,
Salmonella,
Shigella,
13. Staphylococcus aureus,
14. Vibrio cholerae,
15. Aerobic total plate count.
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16. Legonella
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Microbiological Examinations
Accredited Scope

All foodstuffs Samples
Water Samples
(drinking, irrigation, others)

Swab Tests
(food production factories, others)

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Analyzable
Products
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Analyzable
Products/Commodities
 Foodstuffs
Originating from Plants and Animals
 Fresh
Fruits and Vegetables.
 Spices, Herbs, and Medicinal Plants.
 Cereals.
 Dehydrated Products (Dried Fruit & Vegetables, Concentrates)
 Fats and Oils.
 Milk and Dairy Products.
 Honey, Sweeteners, and Candies.
 Fish and Fish Products.
 Environmental
Samples
 Soil
Samples.
 Drinking Water, Ground Water, Surface Water Samples.
 Emissions of Cement Factories Stacks.
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Lab
Premises & Facilities
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LAB AREA & FACILITIES
 The
general part of the analyses, researches
and expert works are done in modern
equipped laboratories furnished with up-todate analytical equipment.
 Working
area: labs are distributed in:
 Main building (2 floors, 450m2/floor)
 Administration building (3 floors, 350
m2/floor)
 Extension new building ( under
construction), 3 floors, 450 m2 for each
 Lab
facility was designed to ensure staff
safety and health and also to keep equipment
work in its favored optimal conditions.
Efficient conditioning system provides the
building with clean, conditioned air.
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COMPUTER INFRASTRUCTURE
 Computer
Servers are located in a room with special power and
temperature requirements, and an uninterrupted power supply (UPS) to
keep equipment and analytical databases operational, provide software
support, and assure data integrity and security.
 The lab has a computer network (starting with reception & ending with
information center). This network is connected to the server which
securely maintains the whole analytical results since 1995 (Lab
Information Center).
DATA MANAGEMENT SYSTEM
QCAP information system features:
 Local
area network (LAN) augmented with Wide area network (WAN),
 Wide range of facilities for electronic transfer of the data via Internet.
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Accreditation &
Technical Scope
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Lab Accreditation
Accreditation Certificate



In 1996 the laboratory has been awarded the
International Accreditation certificate in its field of
analysis by the Finnish branch (FINAS) of the
European Accreditation Centre for Laboratories
(EAL) on basis on ISO/IEC Guide 25 which was
renewed in 2000.
In 2002 the Accreditation certificate was awarded
to the laboratory according to ISO/IEC 17025.
The Certificate was again renewed as testing
Laboratory No. T219 and it is valid until 2013.
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The laboratory is
considered as the only
accredited laboratory in
Egypt in its domain of
works.
As a trusted laboratory in its
field of analysis, the lab has
been granted the accredited
Flexible Scope from FINAS
in November 2008.
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Lab Techniques &
Instrumentations
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 LC
MS-MS
 GC
 Gas
[High Tech Unique Equip.]
MSD
Chromatograph Systems (FPD, FID, NPD, ECD)
 HPLC
Systems (VWD, DAD, FLD)
 GC
MSD (High Resolution) [High Tech Unique Equip.]
In POPs identification.
 GPC
system (Gel Permeation Chromatograph)
Two instruments
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AAS
(Flame & Graphite furnace & hydride)
Digestion
systems
Microwave Digestion system.
 Acid Digestion equipment.

Spectrophotometer
(UV/Vis.)
Weighing equipment

Precision and Analytical Balances
Evaporators


Rotary Evaporators
TurboVap
Sample

System
preparation
Grinders/ Mixers
Analytical
support equipment/appliances
Freeze dryer.
 Accelerated solvent extractor

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QCAP Samples
Facts & Statistics
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Herbs
Number of analysed samples from March 1995- 2009
No.of samples
20000
18000
16000
14000
12000
10000
8000
6000
4000
2000
0
Total No.of herb samples
1995
1996
1997
1998
1999
2000
2001
2002
2003
2004
2005
2006
2007
2008
2009
65
998
1180
2095
3011
4120
3686
7518
9749
12599
18448
17323
13574
10527
12613
Total No.of herb samples
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Summary and Future plan
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Summary of QACP role in pesticide residues and food
contaminates control

Official control of imported-exported shipments

Issuing accredited certificates and rejected the violated
consignments

Inspection at local markets, reporting or published
the results

Training for


Inspectors of AQ
Growers specially at sampling procedures
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Egyptian Exports of fresh products
(2002 – 2008)
Quantity of Exported Agricultural Products from 2002 to 2008
1400000
1200000
1000000
800000
600000
400000
200000
0
2002
2003
2004
2005
quantity/tonnes 721711
839108
1083642
1050442
2006
2007
2008
1027554 1191397.4 1273699.4
years
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 Future
Plan

Expand the scope and the number of analyzed
chemicals by developing and renovating new reliable
methods of analyses.

focusing on food safety to improve Egyptian people
health, increasing the Egyptian food export
competitiveness and to assure the compliance with
national and international food safety standards.
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Summary of QCAP Lab Role
Safe Food…Healthy People
QCAP Lab
Professional Researches
Government /
Policy Makers
Customers
Analytical Methods
Egyptian Consumers
& Egypt Economy
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