Transcript Threat to Funding - Case Western Reserve University

Research Retreat
Current Overview
Tom Hostetter
Vice Chairman for Research
Some Outcomes of Last Retreat 2009
• Agre Society solidified
• Annual Research Day
• Distribution of CTSC resources
• Meeting with SOM and UH leaders
regarding research issues
Research Award Costs ( $ millions)
Year
07- 08
08- 09
09- 10
10- 11
11- 12
DOM
47.2
51.0
64.4
62.5
55.2
SCC
5.3
5.2
4.9
4.9
6.5
Research Cost 2011- 2012
Federal
CV Medicine
Foundatio
n
State
Industry
Total
7,046,710
0
2,515,492
1,080,523
10,642,725
Clinical Pharm
446,135
0
0
0
446,135
Endocrinology
1,175,716
0
2,500
49,005
1,227,221
GI
3,635,636
0
0
238,013
3,873,649
Gen Med
313,600
0
0
0
313,600
Geriatrics
70,229
0
0
0
70,229
Heme/Onc
4,574,093
0
781,040
998,973
6,354,106
ID/HIV/Medicine
23,857,151
192,541
636,169
107,611
24,793,472
Nephrology/Hyp
4,837,604
0
0
70,302
4,907,906
Pulmonary/CC/Slee
p
2,238,545
0
100,000
260,480
2,599,025
0
0
0
0
0
Rheumatology
Sources of Awards 2011- 2012
($ millions)
Federal
State
Foundation Industry
48.2
.2
4.0
2.8
Selected Highlights 2012
Over 40 new or competing renewal grants, one half from NIH
• VAMC- Highly Funded Programs in Implementation,
Quality and Education Research
Basic and applied studies of antibiotic
resistance
GREC revitalized
• CVHigh impact papers in Science and Nature
6 new RO1s and a DARPA grant
Mukesh Jain elected VP of ASCI
• Endo- NIH trials ACCORDION,EDIC
Studies in diabetic retinopathy
• GINIH funded Network for study of Barrett’s
PPG for IBD
Selected Highlights 2012
• Heme/Onc- Cancer Center renewed
High impact papers in NEJM, PLOS Genetics,
JBC, PNAS
• IDProgress in HIV and TB research
Creation of ID and Immunology Institute
Expansion of work in Uganda including CV
Neuro, & Genetics
• Renal/Htn- Leadership in NIH SPRINT and CRIC trials
Ongoing participation in NIH Clinical Trials in
Organ Transplantation
2 endowed faculty positions from Centers for
Dialysis Care
Underrepresented Areas
• Topics
- Human/Population Genetics
- Outcome/Health Care Delivery
- Comparative Effectiveness Research
- Geriatrics
• Grant Types
- K grants - for early career
- P and U grants – for multiple investigators
- Industry
Threats to Funding
•NIH budget has been declining in
constant dollars about 10 years
( ARRA funds in 2009 and 2010
excepted)
•Sequestration of 5- 10% of NIH
budget will lead to about 2500
fewer new grants funded
FASEB
Responses To Funding Threats
• Industry support- now about 6 % of total
Responses To Funding Threats
• Industry support
• Philanthropy
Examples: Harrington Discovery Institute
Centers for Dialysis Care
Responses To Funding Threats
• Industry support
• Philanthropy
• Widen range of Federal Sources
CTSC cores and pilot grants
AHRQ
DOD
PCORI
Patient Centered Outcomes
Institute (PCORI)
• Part of the Affordable Care Act
• 2013 Budget $390 million
• PCORI approved 25 awards, totaling
$40.7 million over three years, to fund
patient-centered comparative clinical
effectiveness research projects
PCORI’s
Research Budget Distribution
Responses To Funding Threats
• Industry support
• Philanthropy
• Widen range of Federal Sources
CTSC cores and pilot grants
AHRQ
DOD
PCORI
• Better grants to Traditional Federal Sources
Multi PI / Team
Collaboration with other departments / institutions
Training
• Med Students Theses
• Residency short track
• Grad Students Tuitions
• F, T and K NIH Grants
Medical Student Theses
• Students are required to write a thesis.
• They have 4 months of committed time and an
optional summer block after 1st year.
• About 8% work in the DOM for their theses
• To let students know of your research, update
your info on the ePortfolio site.
https://casemed.case.edu/ePortfolioFaculty08/
• Also send email to Todd Fennimore, Director of
the Office of Medical Student Research,
[email protected].
Medical Student Research Timeline
Arrive at
CWRU
School of
Medicine
Decide on a
mentor for
the summer
and submit
IRB
applications
& funding
applications.
Year 1
Begin
investigating
areas of
research
interest
Contact potential
mentors for the
summer with the
idea of a project
that leads into the
research block in
year 3.
Submit the
research
proposal
and submit
IRB
application
SUMMER
RESEARCH
Lepow Medical
Student
Research Day
Year 3
4 mo.
Year 2
Schedule Yr 3
including the
research block
M.D. thesis
due by
January 15th
of the 4th
year
Year 4
RESEARCH BLOCK
Lepow Medical
Student
Research Day
Lepow Medical
Student
Research Day
Research
progress
reports due at
1 and 2 month
points
Research
summary due
the Friday
after the end
of the
research block
Work on M.D.
thesis
Percent of Published
Student Research
48%
29%
The value of a research continuum including the summer
between years 1 & 2 as well as the research block in year 3.
Courtesy of Jim Bruzik
Training
• Med Students Theses
• Residency Short Track
• Grad Students Tuitions
• F, T and K NIH Grants
Graduate Student Support by DOM
•Selected PhD students enrolled in SOM with a DOM PI
•DOM will pay their tuition
•PI must pay their stipend from grant, etc and division
guarantee support for the term of the student’s course.
•About 20 students are being supported
Break Outs
•
Breakout #1: Evolving NIH/Federal Funding Landscape
Leaders: Richard Walsh, MD & Fabio Cominelli, MD
•
Breakout #2: Mentoring and Career Development
Leaders: Mukesh Jain, MD & Aaron Proweller, MD
•
Breakout #3: Team Science and Multidisciplinary Research
Leaders: Amitabh Chak, MD, Stanton Gerson, MD & Robert Salata, MD
•
Breakout #4: Enhancing Industry-sponsored Research Opportunities
Leaders: Neal Meropol, MD, & Marco Costa, MD, PhD