Transcript Revolution From Traditional Chinese Medicine to Modern

Revolution From Traditional Chinese
Medicine to Modern HHN & HHP
Presented at MIT CSSA
David Liu, MD, PhD
Professor of Surgery & Oncology
Director, Herbal Medical Center
President, RedsSun Corporation
242 Dorchester St. Boston, USA
New Terminologies Used by Dr. David Liu
HHN = Hi-Tech made Herbal Nutraceutical (products)
HHP = Hi-Tech made Herbal Pharmaceutical (products)
Chinese Made 4 Major Contributions
to the World Civilization
• China is one of ancient countries in the world and Chinese
civilization has been documented since 6,000 years. Chinese
ancestors had made 4 major contributions to the world
civilization:
• (1) The gunpowder for rockets
• (2) The compass for navigation
• (3) The word-typing case for editing and printing
• (4) Paper-manufacture for printing books and
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newspapers
You are Proud Because
• As early as 3,000 years ago Chinese in
writing appeared. The earliest Chinese
characters were carved on shells in the
Shang Dynasty (1600-1100 BC).
Chinese Word for “Sickness” is Ji
• The Chinese word for “sickness” is Ji. It means a person
lying in bed with injury from an arrow, a common
condition in ancient wars.
• The earliest medical textbook in China is called HuangDi-Nei-Jing written during the late Zhou Dynasty (1100770 BC).
• In that time, there were four sorts of oriental medical
workers: physicians for internal diseases, surgeons for
trauma and infections, dietary workers for nutrition and
veterinarian for domestic animals, particularly for military
horses.
Chinese Royal Family Physicians
• In the “Forbidden City” in Beijing where was
the place for Chinese emperors and their
royal families, there were two senior and two
adjunct physicians, four assistants and 20
apprentices for medical and drug affairs caring
royal families.
3 Greatest Physicians in China
• In the history of Chinese medicine, three most famous
physicians made the landmark contributions to the
development of Chinese medicine.
• Bian Que (407-312 BC) was regarded as the inventor of
acupuncture therapy. He also summarized the diagnostic
procedure of a disease into the following four methods:
4 Traditional Diagnostic Methods
• Inspection
• pulse examination
• auscultation-smelling
• history taking
Bian Que’s Story Cited by American
• “One day two men, Lu and Chao, called on the
surgeon Bian Que. He gave them a toxic drink and
they were unconscious for three days. Bian Que
operated and opened their stomachs and explored
the hearts; after removing and interchanging their
organs he gave a wonderful drug and the two men
went home recovered” (Sabiston DC, Textbook of
Surgery).
Hua Tuo (141-207 AD)
• was popularly regarded as the father of traditional
surgery. He prepared an anesthetic powder with
herbs, administered in wine to put patient to sleep
for abdominal operations. This was the earliest
documentation of general anesthesia in medical
history.
Li Shi-Zhen
• Li Shi-Zhen (1518-1593 AD), a great
pharmacologist, who wrote a gigantic medical work
“Ben-Cao-Gang-Mu (The Compendium of Medical
Materials) published in 1590 AD. This work
contained 52 volumes listing 1,892 medical
substances, with detailed description of their
appearance, properties, methods of collection,
preparation and use of them, and providing more
than 1,000 illustrations. There were also more than
10,000 prescriptions listed.
2 billion population around world
on their traditional medicine
• Today, Chinese medicine is widely used in China, Japan,
Korea, Indian, Singapore, Thailand, Vietnams, United
States, Australia, Germany and other countries.
• In China, approximately 60% ± of municipal patients are
treated with Western medicine and 40% ± of them are
treated using herbal medicines. > 50% of farmer patients
are still treated with herbal medicine currently. It has been
estimated that approximately 2.0 billion populations (33%±
population from the around world) are relied upon their
traditional medicine.)
Chinese Medicine is Classified
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Traditional Chinese Medicine (TCM)
Wrapped herbal medicine for
(internal, pediatric, oncological, ENT and dental services)
Surgery
Orthopedics
Gynecology-Obstetrics
Nutrition
Acupuncture and Tui Na or medical massage.
• Acupuncture is only one of fractions of Chinese medicine.
Acupuncture in the USA
• Acupuncture for human being
Yes
• Remote acupuncture for human
quirk
• Acupuncture therapy for cats
quiz
• Acupuncture therapy for dogs
crazy
Modern Chinese Medicine
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Hi-tech made concentrated herbal remedies
Surgery and orthopedics,
Infusion or injection with herbal extracts
Electric or laser-induced acupuncture
Point injection
Integration of deep tissue massage to surface
use of herbal extract and infrared therapy
• Role of herbal remedies in hi-tech bio-drugs
5 Names of Herbal Medicine in the World
Oriental medicine or
Alternative therapy in Western countries
Han-Fan medicine in Japan
Scientific Zhong Yao in Taiwan
Concentrated Zhong Yao in China
HHN & HHP by Dr. David L. Liu in the USA
Difference in Classifications of
Herbs
• Classic Herbs
Folk Herbs
Li Shi Zhen
• 265 sorts
547 sorts
1,892 sorts
TCM
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West M
whole body
regional
Yin-Yang balance inflammation
air-blood integration
heart-lung fun
stasis of air-blood
tumors
Bian-zhen-si-zhi
identical regimen
muscle-joint paralysis
arthritis
overstrain
lumber disc
minor side-effects
sever side-effects
chronic diseases
acute diseases
West Meets East
• During the past 31 years I used to
integrate Western medicine with Chinese
medicine because each of them has their
advantages.
Advantages of Western Medicine
Acute diseases can be effectively
treated with Western medicine, for
example, trauma and injury, massive
bleeding, heart attack and cardiovascular
diseases, surgical and genetic disorders,
early stage of tumors, which can be
radically cured by surgery, transplantation
of organ and tissue, and others.
Advantages of Chinese Medicine
• Many chronic diseases can be efficiently treated
or cured by combined therapy of herbal remedy,
medical massage, infrared & acupuncture, such
as chronic pain in muscle and joint, low back
pain and rheumatoid arthritis, migraine;
autoimmune diseases, depression, deaf, hair
loss, immune deficiency, stroke and elderrelated brain disease.
• More importantly, herbal remedies are nonaddictive, not drug-resistance and side-effect
free if they are prepared in a right recipe.
西医诊断、中药治疗、不断发扬
• 传统中医诊断是几千年或几百年前民间医师们对
疾病的抽象认识和概念，应当学习和发扬，但有
许多方面还需不断完善和提高。例如用中医的观
点来看，由脑溢血或脑血栓造成的脑中风，冠状
动脉狭窄诱发的心绞痛和心肌梗死，肝炎引起的
肝肿大，细菌感染引起的各种脓疡，内分泌失调
所致的痛经和闭经，所有的良性和恶性肿瘤以及
跌打损伤所致的局部组织挫伤和瘀血等等，中医
都用气血瘀滞来解释，并以活血化瘀作治则。显
然这是不全面、不完美和不科学的。
Combination of West-East Medicine
• 西医是以解剖学、生理学和病理学为基础，以多
种化验诊断和高科技术为依据，对疾病进行了病
因和病理的精确分类和定义。例如中耳炎、肺炎、
肝硬化、甲状腺机能亢进，乳腺癌和糖尿病等，
诊断一目了然，方便用药。还有，许多来院就医
病人先前已经西医确诊或治疗，在西药医治无效
时再改中医中药治疗，医师和病人已经习惯用西
医病名作为主诉，所以西医诊断便于病人与医师
之间的对话和交流。
中药治疗的
独特性，优越性，创造性和可治性
• 关于中药治疗的指导思想是因为许多慢性
疾病，如风湿性关节炎、慢性迁延性肝炎、
慢性肾炎、前列腺炎、溃疡性结肠、直肠
炎等应用中药治疗可获得比西药治疗更好
的结果。在许多方面中药有其独特性，优
越性，创造性和可治性。
Current Status of Herbal Medicine
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1) refined injection reagents
2) concentrated herbal tablets or capsules
3) polymers or monomer
4) polymer-recipes gradually recognized by NIH
5) herbal or food supplements have become one of main
streams in Medcare
6) large-pharmaceuticals company manufacture too
7) fake herbal products confuse markets
8) HHN and HHP make top quality of products
9) More people come back to natural medicine
• Only 3,500 people in Beijing a day, but there are 32,000 people to
visit herbal hospitals in Guangzhou a day.
HHN or HHP Products are 5 to 11 Times
More Powerful Than Herbal Materials
LD50 & MTD
半数致死剂量(LD50)和最高耐受剂量（MTD)
肌注半数致死剂量(LD50):
C57BL6小鼠
=
3.4165克/公斤体重
SD 大鼠
=
2.3910克/公斤体重
人体理论剂量
=
0.3758克/公斤体重
肌注最高耐受剂量(MTD):
C57BL6小鼠
=
2.8475克/公斤体重
SD 大鼠
=
1.9932克/公斤体重
人体理论剂量
=
0.3132克/公斤体重
A New Model of 4 Tumors in a Mouse for Screen
Effective Anti-Cancer Herbal Drugs
A New Model of 6 tumors in a mouse for Screen
Effective Anti-Cancer Herbal Drugs
5 of 6 Tumors In This Mouse Regressed by
Intra-Peritoneal Injection With LDL-110
Herbal Remedies Prevent Tumors
• We have for the first time observed this
new finding. It has been confirmed in our
laboratory and also in 3 national medical
university laboratories independently.
• I am very serious to disclose this new
finding.
Oral Intake Herbal Extracts In Vivo Experiment (x 1 M)
------------------------------------------------------------------------------------------------------------Control group
x 4 C57BL6 mice
HE
HE
HE
HE
25 mg/kg
50 mg/kg
100 mg/kg
200 mg/kg
Group
Group
Group
Group
1
2
3
4
x 12 C57BL6 mice
x 12 C57BL6 mice
x 12 C57BL6 mice
x 12 C57BL6 mice
DE
DE
DE
DE
25 mg/kg
50 mg/kg
100 mg/kg
200 mg/kg
Group
Group
Group
Group
5
6
7
8
x12 C57BL6 mice
x12 C57BL6 mice
x12 C57BL6 mice
x12 C57BL6 mice
GE
GE
GE
GE
25 mg/kg
50 mg/kg
100 mg/kg
200 mg/kg
Group 9
Group 10
Group 11
Group 12
x12 C57BL6 mice
x12 C57BL6 mice
x12 C57BL6 mice
x12 C57BL6 mice
1. Blood sampling for serum IFN, IFN, IL2, IL12 on day 5, 10, 15 after starting
treatment.
2. Samples for serum immunoglogublines
3. T cell therapy for tumor vaccines
4. T cell samples for gene therapy
5. Tissue samples for HE staining
6. Thymus and spleen for immunohistochemical staining
7. FACS of splenic cells
These Western Medicines
don’t Work for Me
Boston Herbal Remedy®
Whole Body Eczema Cured
Facial Palsy Cured
Herbal Extract in Facial Care