Transcript Diapositive 1

Alsace Biovalley
Competitiveness Cluster
Illustrating cluster
development dynamics
Taiwan, Oct. 2010
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Alsace BioValley
who/where we are?
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ALSACE BIOVALLEY l WHO/WHERE WE ARE
Welcome to Alsace in France !

A tri-national environment
with a unique concentration
of services & businesses
dedicated to life sciences
and therapeutic innovations
Alsace
Alsace

Hotbed of two of the largest
bioclusters in Europe:
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ALSACE BIOVALLEY CLUSTER l WHO/WHERE WE ARE
Alsace BioValley Cluster
The gateway to biobusiness development in Europe!
 The Alsace BioValley cluster brings together, in Alsace region, in the heart of
Europe,
all life sciences & healthcare players (companies, research centres,
training organisations and universities)
Alsace BioValley
is one of the three French
 One goal: boosting therapeutic innovations and create jobs!
worldclass competitiveness
cluster officially
acknowledged by the
 Alsace BioValley spans two main domains:
French government with
the label «Healthcare»
Bio Pharmaceuticals:
from chemistry and genes toward new drugs
Medical Technologies:
Medical and surgical devices, imaging and robotics
Alsace BioValley is the coordinator of BioValley,
one of the largest life science clusters in
Europe, covering France,
Germany and Switzerland
> www.biovalley.com
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Competitiveness Clusters
A tool for innovation-based
growth
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COMPETITIVENESS CLUSTERS
Clusters…
 A well known concept
Triptyc “Industry – Reseaarch – Education”
developed by M. Porter in the late 70’
Widely applied and proven
USA, Canada…
 A key basis for the new French Industrial Policy
Launched in 2004
through a national competition
Cluster are “labellized” in various industrial domains
“World Class” clusters and “national” clusters are created
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COMPETITIVENESS CLUSTERS l THE FRENCH POLICY’ AIM
The French Policy’s aim
 Identifying high potential clusters and focus public aids on
them
Avoid scattering and increase visibility in specific fields
 Strengthening collaborations between academia & industry
Promoting industry driven collaborative research programs
providing incentives through public funding for R&D in PPP
Developing the “triple helix” dynamic: public research, higher
education & industry
Education as a key tool for industry competitiveness
 Developing a full ecosystem
Education, private financing, IP management,
entrepreneurship, international development, scientific services…
Value chain approach for supporting services
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COMPETITIVENESS CLUSTERS l A DEFINITION
Competitiveness clusters are…
 A combination, within a geographic area, of firms, higher
education and public research organizations
 Sharing a common strategy aimed at generating synergies
and leadership positions
centered on collaborative R&D projects between companies
and public research labs
Over 1,5B€ fund for a 3 years program
 In order to reach the critical mass needed for international
competitiveness and visibility in targeted technological fields
A drastic change ?
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COMPETITIVENESS CLUSTERS l A CHANGE
An important change…
 First there was Public Research…
Focussed on developing new knowledge, science and
technology
 Then… Research becomes a source of innovation…
1999 & 2002: New laws fostering technology transfer and spinoff, creation of public incubators
Industrial Policy remains separate
 2004: Competitiveness clusters – bringing together industrial
policy with Research & Innovation strategy
Both at the National & Regional level
A key tool for alignment and coherence
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Cultural changes within the academic,
industrial & institutional worlds
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The territory & the cluster
Substrat & Landscape
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ALSACE BIOVALLEY l ROOTS
Alsace & cluster-based development
 1998: Creation of Alsace Biovalley & Biovalley tri-national
A shock & an opportunity: merger Ciba Sandoz
 A political choice: acknowledging opportunities and
resources in the life sciences…
industry, public research & education
 A strategic choice: the tri-national dimension
A unique critical mass in Europe, from Strasbourg to Fribourg
& Basel
A coherent employment area: workers & companies do not
see
borders
Alsace Biovalley: coordinator of the tri-national network
Over 7M€ EU funding since then
Maturation process needs time
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THE TERRITORY & THE CLUSTER l HISTORY
Alsace BioValley & Biovalley trinational
History
Over 10 years for three level of maturity and cumulative activities
 1998 > 2002 Focus on the social network
l Creation of Alsace BioValley and BioValley trinational clusters
l Provide people with opportunities to meet and exchange
l Develop identity and belonging
 2002 > 2005 Focus on international positioning and brand
l Strong presence at international level, sophisticated communication tool box
l Be on the “radar screen”
l First “services to members” related to international events
l 2005: Alsace labellized as World Class Competitiveness Cluster
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 2006 > …… Focus on economic development
l Serving actors: companies, laboratories, training & education centers
l And serving the territory
Oct.. 2010
Are 10 years
too long?
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THE TERRITORY & THE CLUSTER – SUBSTRAT & LANDSCAPE
Clusters are
anchored in the territory
 Key components
l A substrat: Industry, Research, Training
l A collective dynamic, supported by public bodies & agencies
 University has a pivotal role
l World class research as a source of technologies and innovation
High quality research = dense industrial relations
l Performing TTOs: a fundamental connection towards businesses
Professionalism AND resources
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l Adapted initial and continuous training:
Attrac and retain
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THE TERRITORY & THE CLUSTER – SUBSTRAT & LANDSCAPE
BioValley susbtrat:
World class research & training

8
universities & university institutes
dedicated to life sciences
A unique organisation!

15 000 scientists

100 000 students

30

11
qualified technology platforms
for scientific services
life sciences parks
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THE TERRITORY & THE CLUSTER – SUBSTRAT & LANDSCAPE
BioValley susbtrat:
A unique industrial density in the Upper Rhine Valley

600
companies
l 350 Pharma Biotech
l 250 Medical devices

50 000 people
working in life sciences
France + Germany + Switzerland
rank among the top 4 for the
production of drugs
40% of the biggest Pharma in the
world are located in the trinational
area
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THE TERRITORY & THE CLUSTER – SUBSTRAT & LANDSCAPE
Alsace BioValley landscape
 Beyond Research & Training organizations
l 2 universities and 3 engineering schools
l 3 national research operators (CNRS, INSERM, INRA)
 A number of structures to support laboratories and companies
l Regional (and departemental…) economic development agencies
Some generalist and some specialists (photonics, image…)
l Regional Innovation Agency
l Regional incubators
l TTOs and Conectus
l Chambers of Commerce and Industry
l CEEI: European Center for Enterprise & Innovation
All these organisations
have people on the field!
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THE TERRITORY & THE CLUSTER – SUBSTRAT & LANDSCAPE
Governance as a key tool to ensure
integration in regional innovation system
 Separating roles within the cluster
l Actors:
companies, research laboratories, training and education:
a dedicated association, by and for actors
l Agencies & Organizations:
working on the field
l Public funders
 The dedicated association coordinates the cluster, but is not the
cluster!
l Alsace BioValley®
is the brand under which the cluster operates
 A high level group dedicated to prospective
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l Structuring the road map
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THE TERRITORY & THE CLUSTER – SUBSTRAT & LANDSCAPE
Governance as a key tool to ensure
integration in regional innovation system
 Alsace BioValley Executive Committee:
all agencies working on the field are
involved in the cluster governance
l ONE strategie & action plan for the cluster
l Shared responsability and accountability
in front of (shared) public funders
Integration is key
to coherence.
Speed and simplicity
are our objectives!
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THE TERRITORY & THE CLUSTER l STRATEGY
Shared, articulated and focussed strategy
 Strengthening competitiveness of actors through a set of
services
l Support for:
collaborative R&D projects, representation at partnering, matchmaking,
strategic intelligence platform…
 Strengthening competitiveness & attractiveness of territories
l
l
l
l
Developing a set of technology platforms for services
Developing and adapting training programs
Developing infrastructures
Ensure availability of capital funding troughout the chain
 Strengthening international positioning, network and visibility
l Building a critical mass to be attractive
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l Developing cluster to cluster relationship to expand the pool
of
for our actors
Oct..opportunities
2010
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5 years of competitiveness
cluster in Alsace
Illustrating results
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5 YEARS OF COMPETITIVENESS CLUSTER IN ALSACE l ILLUSTRATING RESULTS
10 years objectives
3 key indicators!
OVER 10 YEARS

5 000 jobs created
AFTER
 over
5
YEARS
1 800 direct
& indirect jobs created

Doubling of PPPs
 Increase of

90 companies created

60%
43 companies created or
in incubation
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5 YEARS OF COMPETITIVENESS CLUSTER IN ALSACE l ILLUSTRATING RESULTS
Actors competitiveness: illustrating R&D projects
"Anubis" project > Surgical and Medical Imaging and Robotics
 Subject:
The objective pursued by the ANUBIS project is to develop transluminal surgery, a surgery which implies that
the surgicalaction is performed on organs via natural orifices such as the stomach (transgastric) or the vagina
(transvaginal). Thus the patient will neither have visible scars nor pain - possible risks of post-surgery
complications will also be reduced. This development led to the creation of new surgical tools according to two
major lines: mechanical tools directly controlled by the surgeon and robotised tools. The project also led to the
development of a dedicated surgical training, taught at IRCAD, which is necessaryto learn this new surgical
technique.
RESULT 1
l
World first in Surgery
2
l
New generation of endoscope
RESULT 3
l
Start-up created
RESULT
Ambitions
To position France and Alsace as world leaders
in the field of transluminal surgery by
developing new surgical tools associated to
high-level training.
PARTNERS
Coordinator:
Partners:
Total budget:
7.09 M€
Grants:
1.79 M€
Funding partners:
Direction Générale des Entreprises
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5 YEARS OF COMPETITIVENESS CLUSTER IN ALSACE l ILLUSTRATING RESULTS
Actors competitiveness: illustrating R&D projects
"Dscreen" project > Surgical and Medical Imaging and Robotics
 Subject:
The aim of dScreen is to develop a novel system for high throughput screening for drug discovery,
based on digital microfluidics. In concrete terms, aqueous droplets are dispersed in a carrier oil within a microfluidic
system and each droplet functions as an independent microreactor. Compared to conventional screening techniques,
volumes can be reduced by a factor of 103 to 106, and the throughput can be increased by a factor of 104.
PARTNERS
The partnership is compact and fully complementary, between the technology developer (ULP-CNRS), the equipment
Coordinator:
specialist (RainDance Technologies) and the final user (sanofi-aventis)..
RESULT 1
l
Raindance Technologies chooses Strasbourg to create
its European affiliate
2
l
Technology platform to be developed for screening services
RESULT
Partners:
Total budget:
1.40 M€
Grants:
Ambitions
This project starts with a « Proof of Concept »
phase for this new technology. If the results
confirm our hypothesis, a second phase will
follow for industrial development.
0.30 M€
Funding partners:
Alsace Région for ULP-CNRS
Oséo for RainDance
Sanofi-Aventis did not
request public funding
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5 YEARS OF COMPETITIVENESS CLUSTER IN ALSACE l ILLUSTRATING RESULTS
Actors competitiveness: illustrating R&D projects
Life & chemical
sciences

51 project labellized
 over

90 partners
110 M€ of
R&D investments
(75% private)
Physics, NICT, photonics, robotics…
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4 YEARS OF COMPETITIVENESS CLUSTER IN ALSACE l ILLUSTRATING RESULTS
Actors competitiveness:
illustrating matching activities
Currently working
on a Euro
25 million european
facility following
such a deal
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4 YEARS OF COMPETITIVENESS CLUSTER IN ALSACE l ILLUSTRATING RESULTS
Working on territory competitiveness
 May 6th, 2009
l University of Strasbourg and North Caroline State University will partner
within Alsace Biovalley Cluster to develop new programs and infrastructures
for training in bioproduction and aseptic production
 September 9th, 2008
l Alsace Biovalley and GE Healthcare sign a partnership agreement
to create and develop a molecular imaging plateform
 July 1st, 2008
l Alsace Biovalley announces Euro 11 millions project for life sciences
building hosting research, scientific expertise and services
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THE TERRITORY & THE CLUSTER l ILLUSTRATING RESULTS
Strenghtening international positioning beyond Biovalley
The Life Science Corridor (LCF)
Building a healthcare
shiled to fight
infectious diseases
> Diagnostic, vaccines
& new therapies, Systems
A unique and broad
approach throughout
the continuum of Cancer
> Prevention,
diagnostic, treatment
Therapeutic innovations
for tomorrow’s healthcare
> Bio Pharmaceuticals :
from chemistry and genes
towards drugs
> Medical Technologies :
medical and surgical devices,
imaging and robotics
LCF represents more than
1,200 companies
involving > 80,000 jobs
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A structuring role for
Competitiveness clusters
Illustration of 2 large programs
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BTEC | Background
 Staff sourcing and continuous eduction: a challenge
for industry players
• Available training not suited for industrial operations in aseptic
environment
• Turn over of younger personnel
Partnership between Strasbourg University & North
Carolina State University (USA)
• Common training modules, short courses and internships
• Staff and faculty exchange
• Creation of a dedicated training center in Alsace, capitalizing on
BTEC’s experience.
Partenaires :
UdS
BTEC North Carolina
Alsace BioValley
Partenaires industriels
Alsace Biovalley cluster role:
• Federating industry actors
• Ensure new programs match industry needs
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• financial engineering and fund raising
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Pharma & bioproduction
Cellules vivantes
• France 1st european country for drug production
• 108 407 jobs / 50 Mds€ gross revenues
• 20% of French GDP in 2020 (current 13%)
• Growing specialization and technical requirements for staff
• Growing needs and investments in continuous education (63,3%
staff have followed continued education in 2008, as opposed
to 42.9 % in other industriies)
Médicaments
• Strasbourg University is the leading provider of continuous
eduction to pharma industry in France
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Why a « Factory School » ?
From school to industry… drastic differences !
School….
High technicity, ultra clean
To industry
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Regulatory constraints and working
conditions…
Hard to teach in a classroom!
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BTEC | Training offer
Formations en alternance
– IFIS Programme de requalification dans
une démarche GPEC
Formations continues
Formations initiales
– Université de Strasbourg , UdS Enseignements pratiques
et modules complémentaires
niveau BAC, BAC+2,
L, M, D, ingénieurs
BTEC
– Dépt formation continue UdS
et IFIS Courtes (2j à 2 sem.) sur
catalogue
et sur mesure
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Medical Technologies Campus
Towards a leading position in Europe
A urban and economic project: over 250M€ investment
Friche HUS
7 ha
Haras
2
4
3
1
NHC
4
IHU
Institute of Image-Guided
MIS
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ITM
Institute for biomedical
Implants
1
1
Technoparc
MedTech business
Centre
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Clusters approach for regional
economic development
The Alsacian illustration
in Life Sciences l Key learning
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CLUSTERS APPROACH FOR REGIONAL ECONOMIC DEVELOPMENT
l THE ALSACIAN ILLUSTRATION IN LIFE SCIENCES
At the cluster level
 Integration within the territorial eco-system is key
l Clusters develop by leveraging existing assets & resources
 Compensate fragmentation & absorb complexity…
l Fragmentation = Strong repulsing feature for companies
l 1 cluster = 1 identity = 1 territorial offer
 … towards a dynamic of co-construction between agencies
l Ensure strategic coherence & coordination, avoid duplication and conflicts
 International is accessible, but you need critical mass …
l Achieved through Life Science Corridor France
 But territorial structuration remains key
l Key source of competitiveness…
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CLUSTERS APPROACH FOR REGIONAL ECONOMIC DEVELOPMENT
l THE ALSACIAN ILLUSTRATION IN LIFE SCIENCES
Thank you for your attention!
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