Transcript Technology Development of Image

NIBIB Perspective on ImageGuided Interventions Research
John W. Haller, Ph.D.
Acting Director, Division of Applied
Science and Technology
National Institute of Biomedical
Imaging and Bioengineering
October 19, 2006
NATIONAL INSTITUTES OF HEALTH
U.S. DEPARTMENT OF HEALTH & HUMAN SERVICES
Outline of Talk
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Definition of Image-Guided Interventions
What lead to the RFA for IGI?
Open Source Technologies
Open Architecture
Open Interface
Future Directions
Definition of Image-Guided
Interventions
• All image-guided
interventions require
– a source of images
– real-time display
linked to the
intervention & patient
– target definition in the
context of real 3D
space of the patient…
as distinguished
from virtual image
space.
Image courtesy of F. Jolesz
Image-Guided Interventions
• Images used DURING intervention
– Preoperative or intraoperative images are used
during a procedure to guide physician to a target
– Both images AND intervention must be involved
• Image-guided Interventions include
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Minimally invasive surgery
Image-guided Biopsy
Radiation Treatment
Image-guided radiofrequency ablation
Cryoablation
Endoscopic interventions
Other image-guided therapies
Recommendations from the
2002 & 2004 IGI Workshops
• A technical working group is needed to
develop standardized system interfaces.
• Collaborations between academia and
industry should be facilitated.
• Exploit grid computing and informatics
infrastructure…
• Heterogeneous data integration/fusion.
• Platform technologies for IGI systems should
be seamlessly integrated for a wide range of
clinical applications…
Federal Agency Retreat
January 2006
Standards for IGI
• Standards for IGI include not only informatics
standards, but also standards for IGI imaging
and interventional devices.
• Standards for IGI could facilitate the integration
of imaging and data systems
• Establish standards for data acquisition, storage,
communication, software, interoperability of
systems.
• IGI standards will enable interoperability and plugand-play capability.
Concept for Image-Guided
Interventions Initiative
• Disruptive technologies
– Minimally invasive IGI technologies that replace
current technologies
• Two-phase, 8 yr. initiative, $40M Total Cost
– Phase I: 3 yr Development/feasibility studies,
$300K Direct Costs Per Year
– Phase II: 4-5 years in duration
$750K direct costs per year
• ≈ Five new IGI Centers (Cooperative Agreements)
• Goal-directed, problem solving
Technology Development of ImageGuided Interventions: Phase I (R21)
RFA-EB-06-003
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Receipt Date: October 23, 2006
Project period of up to three years
Direct costs up to $300,000 per year.
$5,000,000 per year NIBIB set aside
Goal is to produce disruptive
technologies to replace current
treatments with minimally invasive, imageguided interventions.
Technology Development of Image-Guided
Interventions: Open Source
RFA-EB-06-003
Reviewers will be instructed to evaluate the
software dissemination plan…
1. The software should be freely available ….
2. … the software should be transferable such that
another individual or team can continue
development…
3. … should include the ability of researchers to
modify the source code and to share
modifications …
4. Commercialization … should be permissible.
Technology Development of
Image-Guided Interventions
• STANDARDS
RFA-EB-06-003
The software should adhere to community-based
standards…
• OPEN ARCHITECTURE
– … open-architecture whose specifications are
made public (i.e. the interface to other systems
should be non-proprietary).
– …open architecture will allow for the future
integration and inter-operation of new IGI
components…
Technology Development of
Image-Guided Interventions
RFA-EB-06-003
• DATA SHARING
– … data sharing plans will be considered by
Program staff when making recommendations
about funding …
Hardware/System Access
• Open technologies
vs.
• Open architectures
vs.
• Open interfaces
vs.
• Closed/Proprietary systems
Open Source Technology
• Cholera Treatment Device
Device for improved set up, operation and
monitoring of intravenous drip infusion
systems, the only treatment for severe
cases of cholera.
WIRED Issue 11.11 |
November 2003
Open Architecture
• Open architecture allows
users to see inside the
architecture without proprietary
constraints.
• All or parts of the architecture
are published.
• … i.e., accessibility
to a machine by any
other machine or
software.
Intervention
Device
(e.g., Surgical Workstation or Robot)
Open
Interface
Open
Interface
(API)
An API that
does not
require
royalties for
access and
usage is
called
"open."
An application programming interface (API) is
the interface that a computer system, library or
application provides in order to allow requests
for services to be made of it by other computer
programs, and/or to allow data to be
exchanged between them.
http://en.wikipedia.org/wiki/API
DaVinci
Intervention
Robot
Open
Interface
Device
(e.g., Robot)
An API that
does not
require
royalties for
access and
usage is
called
"open."
Open
Interface
(API)
Tracking
Device
Disclaimer
• The follow slides do not represent the views
of the NIBIB, NIH or Major League Baseball.
We need another quantum jump of imaging in medicine. I envision that in 30 to 40
years there will be no open surgery…there will be only image-guided microsurgery.
-Elias Zerhouni, MD
January 2003
Future IGI Activities
• Encourage the use of open source
software and open architectures
• Reduce health disparities both
domestically and globally through new and
affordable [IGI] technologies.
• Establish working group for IGI standards?
• Develop a Demonstration Project?
DaVinci
Open Interface
Demonstration
Projects?
Robot
JHU
Robot
Open Interface
(API)
Medtronic
Stealthstation
Brainlab
Reductio ad absurdum?
DaVinci
Robot
JHU
Robot
Philips
Scanner
Siemens
Scanner
GE
Scanner
Medtronic
Stealthstation
API
Open Interface
Brainlab
ITK
Analyze
Image
Databases
Summary
• Continuum of hardware/system access
Open-source
Technology
Open
Architecture
Open
Interface
Closed
Proprietary
• Suggested action items
1. Establish working group for IGI standards
2. Develop a Demonstration Project
• What role can NIH play to promote
open architectures/open interfaces?
[email protected]