Transcript Team name - University of Wisconsin–Madison

William Sanford
Karissa Thoma
Dan Frost
Allie Finney
Client: Dr. Mark Reichelderfer
Advisor: Dr. Willis Tompkins
Overview
1.
2.
3.
4.
5.
6.
7.
Background
Problem Statement
Design Constraints
Previous design work
Lab Jacks
Pressure Sensor Sealants
Future Work
Esophageal Strictures
•Dysphagia= dyswith difficulty +phagiawith eating
•Causes
•GERD majority
•25% other problems
•Eosinophilic esophagitis
UW-Hospital, Dr. Mark Reichelderfer
Eosinophilic Esophagitis
•Adolescents and young men
•History of food and environmental allergies
•Difficult to treat:
•Associated with mucosal tearing and perforation
http://www.nature.com/gi
mo/contents/pt1/images/g
imo49-f4.jpg
Dilation
Balloon
•Dilates radially
increasing lumen
•TTS scope (through
the scope)
http://homepages.cae.wisc.edu/~bme40
2/esophageal_structures_s06/images/ba
lloondialation.bmp
Perforations Dependent on:
• Clinician’s experience
• Equipment
http://www.dkimages.com/discover/previews/881/28882.
JPG
Problem Statement
•Measure pressure in balloon
•Graph volume/pressure curve in real time
•Obtain test data on tissue compliance
•Be aesthetically pleasing for hospital setting
•Eventually be commercially available
Design Constraints
•Work with current dilation procedure
•Provide real time data
•Safety
•Equip laptop for hospital use
•Provide warning of esophageal perforation
•Compact enough for hospital setting
Previous
Work
•Syringe is filled with saline
•Pressure measured with
disposable pressure transducer
•Volume measured with linear
potentiometer
•Outputs are connected to
computer
•Designed LabVIEW circuit for real
time graph
Seashore, K. et. al. (2006). Device for Dilating Esophageal
Strictures.
LabVIEW Circuit
Lab Jacks-LabJack U12
 Pros
 Built-in power supply
 Large input range
 LabVIEW compatible
 USB-based
 Cons
 Cost
 No -5V supply
http://www.labjack.com/labjack_u12.php?p
rodId=27
PMD-1208LS
 Pros
 USB
 Power supply
 LabVIEW compatible
 Cons
 No -5V supply
 Poor user interface
http://wwwzeuthen.desy.de/apewww/APE/hardware/APEmille/Temperat
ure/PMD-1208LS.pdf
LabJack UE9 Pro
 Pros
 Wireless transmission
 USB
 LabVIEW compatible
 Cons
 Cost
 Bulky
http://www.labjack.com/labjack_ue9.php?prodId=46
LabJack Matrix
Weight
U12
PMD
UE9
Power
Supply
25
16
16
16
Inputs
20
20
20
20
User
friendly
10
8
5
9
LabVIEW
20
20
20
20
Size
15
13
13
9
Cost
10
5
9
0
Total
100
82
83
74
Metal adhesives - MK 1325
 Pros
 High strength
 Thread sealant
 Low viscosity
 Cons
 Irreversible
 From Germany
http://www.bestklebstoffe.com/media/datenblaetter/englisch/tiMK1325ERev001.pdf?PHPSESSID=952e86e08d406e9e05
a6b976cf39c2e4
Gorilla Glue
 Pros
 Waterproof
 Good for dissimilar
surfaces
 Thread sealant
 Easy to obtain
 Cons
 Glue expansion
http://www.gorillaglue.com/home/gorilla-glue/product-detail.aspx
Megaloc
 Pros
 12000 Psi strength
 Thread sealant
 Non-toxic
 Inexpensive
 Cons
http://www.herchem.com/specs/megaloc.pdf
Sealant Matrix 2
Weight MK 1325
Gorilla
Megaloc
50
50
30
45
Reversibility 10
0
5
3
Toxicity
20
20
20
20
Ease of use
5
4
5
5
Availability
5
1
5
3
Cost
10
?
9
9
Total
100
75
74
85
Strength
Future Work
 Fix pressure sensor
 Obtain 10 atm seal
 Configure device with
Lab Jack
 Configure to hospital
laptop
 IRB approval/testing
References
Fass, R. M. (2008). Approach to the patient with
dysphagia. Retrieved Jan. 31, 2008 from
Moises, G. M. (2008). Complications of esophageal
stricture dilation. Retrieved Jan 31, 2008 from
Moises, G. M. (2008). Management of benign esophageal
strictures. Retrieved Jan. 31 2008, 2008 from
www.uptodate.com