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PubMed Elsevier HS B&J, Taiwan Presented By: Gary Cheng Date:Feb 21 2012 Outline What is MEDLINE/PubMed in NLM? What is Index Medicus? History of NLM and MEDLINE MEDLINE®/PubMed® Data Element (Field) Descriptions Introduction of PubMed/MEDLINE Function LinkOut MeSH Limit Subheading Relative articles Clinical Queries My NCBI 2 Index Medicus MEDLINE的前身為美國《醫學索引》是當前世界上最著名的大型生物 醫學文獻檢索刊物,1879年創刊,由美國國立醫學圖書館(The National Library of Medicine)編輯出版。 1.期刊索引 月刊,每年ㄧ卷,每卷十二期,每期內容分三個部份,分兩冊 出版。 Part 1 :Subject Section Part 2 : Author Section Bibliography of Medical Reviews 2.MeSH 用於尋找IM主題檢索,每年隨IM的第一期出版。 3 Historical Record of Index Medicus 4 Milestones in NLM History http://www.nlm.nih.gov/about/nlmhistory.html 1836 Library of the Office of the Surgeon General of the Army established. 1879 First volume of Index Medicus published. 1956 October 1 Act of Congress moved Armed Forces Medical Library to Public Health Service (PHS) and rechristened it the National Library of Medicine (NLM). 1971 October MEDLINE was initiated to provide online access. 1993 October NLM's Internet World Wide Web site (www.nlm.nih.gov) appeared. 1997 June 26 Web-based access to NLM's MEDLINE became available free of charge. 1998 October MedlinePlus created to provide access to consumer health information. 2000 February 29 ClinicalTrials.gov, an online resource designed to give the public easy access to information about research studies, was launched. 5 NLM Programs and Services Annual Report - Fiscal Year 1997 6 Content of Medline/PubMed 36 data bases in PubMed MEDLINE was most important 5200 titles from USA 自1966至現在,一億六千多萬書目資料,且每個月以 20000筆的速度增加。 Medical Subject Headings (MeSH®). 7 MEDLINE®/PubMed® Data Element (Field) Descriptions 8 MEDLINE®/PubMed® Data Element (Field) Descriptions PPMID- 19422719 TI - A complementary method for detecting qi vacuity. AB - BACKGROUND: Qi vacuity (QV) is defined by traditional Chinese medicine as a loss of energy in the human body. An objective method for detecting QV was notav ailable until recently, however. The automatic reflective diagnosis system…… AD - Department of Internal Medicine, Show Chwan Memorial Hospital, No. 542, Sec 1. Chung-Shang Road, Changhua City, Taiwan. [email protected] FAU - Chen, Ming-Feng MH - Adolescent MH - Adult MH - Case-Control Studies MH - *Diagnosis MH - Female MH - *Galvanic Skin Response MH - Humans MH - Male MH - *Medicine, Chinese Traditional MH - Methods SO - BMC Complement Altern Med. 2009 May 8;9:12. 9 MeSH 自然語言 (nature language) 與索引 (index term) - 以索引搜尋的目的在於增加檢索專一度 (specificity) 優點 缺點 自然語言 可搜尋似是而非或未 可能會得到許多不相 經索引分類的主題 關的文獻,未考慮同 義字或時態/語系差異 索引 可透過索引可歸類相 須重複檢索較花時間 關同義字 Note 常見索引 (index term) 分類系統例如美國國家醫學圖書館 的MeSH (medical subheading), 已經可以 時以自然語言及MeSH進行搜尋 以MeSH名詞搜尋並非萬無一失 - PubMed常見狀態分類 (status subset) MeSH 篇數 381428 as supplied by publisher 出版商提供引用 418151 加工中 in process 標籤 狀態 indexed for MEDLINE 加工完畢 ◎ 19035076 Note 還沒加工完畢的文章,僅用MeSH名詞是搜尋不到的!! 破解: your keywords AND (inprocess[sb] OR publisher[sb] OR pubmednotmedline[sb]) PubMed Limits 使用Limits後, In process 、supplied by publisher、非Medline 的文獻,將被排除~ 因為 Limits 條件大多是已加工索引完成書目才具有 破解: your keywords AND (inprocess[sb] OR publisher[sb] OR pubmednotmedline[sb]) #9 (區塊內OR;區塊間AND) 勿與Type of Article併用 12 常用MeSH名詞副標題 (subheading) 組合 簡寫 副標題 用途 AE DT Adverse effects Drug therapy 不良反應相關研究 藥物治療相關研究 DU PK Diagnostic use Pharmacokinetics 作為診斷工具研究 藥物動力學研究 PD Pharmacology 藥理學相關研究 PO Poisoning 毒理相關研究 PC TU Prevention and control 預防相關研究 Therapeutic use 治療用途研究 varenicline/drug therapy (後面不需加上[mh]) Relative Articles 比對相關文獻 (related citations) 功能 內建語法會根據摘要、標題與MeSH名詞,配合字元權重 算出最接近的鄰居 (neighborhood) Clinical Queries using Research Methodology Filters Category Optimized For Sensitive Specific sensitive/ broad 99% 70% ((clinical[Title/Abstract] AND trial[Title/Abstract]) OR clinical trials[MeSH Terms] OR clinical trial[Publication Type] OR random*[Title/Abstract] OR random allocation[MeSH Terms] OR therapeutic use[MeSH Subheading]) specific/ narrow 93% 97% (randomized controlled trial[Publication Type] OR (randomized[Title/Abstract] AND controlled[Title/Abstract] AND trial[Title/Abstract])) sensitive/ broad 98% 74% (sensitiv*[Title/Abstract] OR sensitivity and specificity[MeSH Terms] OR diagnos*[Title/Abstract] OR diagnosis[MeSH:noexp] OR diagnostic * [MeSH:noexp] OR diagnosis,differential[MeSH:noexp] OR diagnosis[Subheading:noexp]) specific/ narrow 64% 98% (specificity[Title/Abstract]) sensitive/ broad 93% 63% (risk*[Title/Abstract] OR risk*[MeSH:noexp] OR risk *[MeSH:noexp] OR cohort studies[MeSH Terms] OR group*[Text Word]) specific/ narrow 51% 95% ((relative[Title/Abstract] AND risk*[Title/Abstract]) OR (relative risk[Text Word]) OR risks[Text Word] OR cohort studies[MeSH:noexp] OR (cohort[Title/Abstract] AND stud*[Title/Abstract])) sensitive/ broad 90% 80% (incidence[MeSH:noexp] OR mortality[MeSH Terms] OR follow up studies[MeSH:noexp] OR prognos*[Text Word] OR predict*[Text Word] OR course*[Text Word]) specific/ narrow 52% 94% (prognos*[Title/Abstract] OR (first[Title/Abstract] AND episode[Title/Abstract]) OR cohort[Title/Abstract]) sensitive/ broad 96% 79% (predict*[tiab] OR predictive value of tests[mh] OR scor*[tiab] OR observ*[tiab] OR observer variation[mh]) specific/ narrow 54% 99% (validation[tiab] OR validate[tiab]) therapy diagnosis etiology PubMed Equivalent prognosis clinical prediction guides EBM Unfiltered Resour 語法 Save filter as (命名) Query Terms (查詢語法) Therapy‧RCTs Therapy/Narrow[Filter] Therapy‧Clinical Trials Therapy/Broad[Filter] Diagnosis/Broad Diagnosis/Narrow[Filter] Prognosis /Broad Prognosis/Broad[Filter] Etiology /Broad Etiology/Broad[Filter] Qualitative /Broad interview*[tiab] OR psychology[sh:noexp] OR health services administration[mesh] 更多篩選機制(包括Costs, Economics, Clinical Prediction Guides) 參考: http://hiru.mcmaster.ca/hiru/HIRU_Hedges_MEDLINE_Strategies.aspx Thanks for your attention