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Consumer life goals re food

Be healthy for longer Be free from Health Problems Give Children a Good Start

Huge global issues in nutrition

4bn people affected by malnutrition deserve the chance to develop physically & mentally to get more out of life.

50% of world’s population have blood cholesterol that’s too high.

30% of world’s population have blood pressure that’s too high.

A vision for improving population health

Target population for food industries & public healthcare Target population for pharma industries Healthy Unhealthy Green MR and van der Ouderaa F, Nature Pharmacogenomics - 2003

ETP Food for Life

Vision

An

effective integration

of strategically-focussed, trans-national, concerted research in the

nutritional-, food- and consumer sciences and food chain management

will deliver

innovative, novel and improved food products

for, and to, national, regional and global markets in line with

consumer needs and expectations

. These products,

together with recommended changes in dietary regimes and lifestyles

, will have a

positive impact on public health and overall quality of life

(‘adding life to years’). Such targeted activities will support

a successful and competitive pan European agro-food industry

having

global business leadership securely based on economic growth, technology transfer, sustainable food production and consumer confidence

.

European Technology Platform Food for Life

Communication, Training & Technology Transfer Food & Health Food Quality & Manu facturing Food & Consumer Food Safety Sustainable Food Production Food Chain Management

Stakeholders’ proposal for a Strategic Research Agenda

April, 2006

The key innovation challenges

 The development of this ETP has been driven by the activities of its eight

Working Groups

 To optimize the synergy of its internal interactions, the Stakeholders’ Strategic Research Agenda, SSRA, has been drafted according to the seven

Key Challenges for Innovation

facing the European agri food sector  These Challenges map closely with the goals and deliverables of the individual Working Groups

Healthy ageing:

Goal Well-being/ appearance Age Add life to years

Food & Health Delivering a healthy diet

Working group:   Prof Wim Saris, DMS & Univ Maastricht, NL (chair) Dr Jacqueline Castenmiller, WCFS, NL (fascilitator)           Prof Nils-Georg Asp, LU, SE Prof Robert-Jan Brummer, WCFS, NL Dr Irene Corthesy, CRN, Nestl é, CH Prof Hannelore Daniel, Techn Univ, München, D Dr Gerd Hazer, Kraft, D Dr Ian Johnson, IFR, Norwich, UK Prof Bertold Koletzko, Univ München, D Prof Ian Macdonald, Univ Nottingham,UK Dr Gert Meijer, Unilever, NL Dr Moïse Riboh, Danone, F

Food & Health: priority research areas

INFANT BRAIN FUNCTIONS IMMUNE- & INTESTINAL FUNCTIONS METABOLIC FUNCTIONS ELDERLY

How did we work?



TOWARDS A STRATEGIC RESEARCH AGENDA FOR FOOD, NUTRITION & HEALTH

• 1.

table.

Please define research questions for each cell in the • 2.

For each of the research questions, describe: – - (Knowledge) deliverables; – - When to reach these deliverables: 2010, 2015 or 2020; – - Bottlenecks to solve the research questions; – - The breakthrough potential on a scale from 1 to 5 (low to high potential)? This is about the potential of the research to contributing to breakthrough chances or opening up new horizons for application-inspired research.

How did we work?

2



Table. Scientific targets Life cycle Metabolic function

Cell plasticity

Immune function Brain function

Cell plasticity Cell plasticity In-utero, new borns, infants and young children -To optimise development

1

-Early disease prevention – minimising risk for later life

2

-Physical activity

3

-Programming and imprinting

4

-Optimal weaning foods to maximise resistance and to minimise food allergy

5

-Immune tolerance

6

-Nutrition and cognitive function

7

-Brain conditioning (e.g., taste perception)

8

How did we work

3 N o.

1 2

Research question Knowledge deliverables Bottlenecks

Which nutritional factors during pregnancy determine optim al foetal development? How im portant is caloric excess and macronutrient im balance for early risk factor development? Basis for development of optim al foods/diets Refi ned recomm endat ions on infant nutrition Dietary survey methodology, ethical constraints limi ting intervention studies Limi ted possibili ties to perform intervention studies

When Break through potenial

2015 3 2015 3

Food & Health

Delivering a healthy diet

 Understanding brain function in relation to diet  Understanding dietary effects on immune and intestinal function  Understanding the link between diet and metabolic function (obesity and associated metabolic disorders)  Understanding consumer behaviour in relation to health and nutrition

Goal 1: Understanding brain function in relation to diet

 Diet and cognitive functions  Brain conditioning  Mood and optimal performance  Prevention of cognitive decline  Food intake regulation and hunger/satiety  Nutrition and interorgan signalling - esp gut-central nervous system interaction

Goal 2 Understanding dietary effects on immune and intestinal function

 Modify systemic inflammatory activity by diet  Dietary factors that improve barrier functions  Biomarkers for intestinal health  Diet before and during pregnancy and lactation immunefunction and allergy  Improved allergome database for foods

Goal 3

Understanding the link between diet and metabolic function (obesity and associated metabolic disorders

 Early biomarkers of metabolic syndrome  Individual variations in metabolic energy efficiency  Food components that regulate food intake and increase termogenesis  Intervention strategies  Counteract age-associated muscle wasting  Low-grade inflammation - obesity/insulin resistance/metabolic syndrome  Epigenetic events - chronic disease  Maternal and infant recommendations for opt health  Meal composition and size - energy uptake, satiety

Goal 4 Understanding consumer behaviour in relation to health and nutrition

 Key determinants of food habits  Biological determinants in food choice  Methodology to understand and quantify determinants  Perception and determinants of ”healthy lifestyle”  Better tools for effective communication  Consumer knowledge - consumer understanding of health schemes, health claims, simplified labelling and personalised nutrition based on nutrigenomics

Horizontal Activities

The role of Horizontal Activities is to

optimise the impact of the ETP

through: 

Ensuring internal complementarity:

Minimising gaps or duplication across the SRA 

Establishing effective links with nationally- and FP6- funded projects, and other ETPs

Maximising the effectiveness of European food chain science 

Establishing the Mirror Group:

Effecting a dialogue with national funding bodies, policy makers and opinion formers, COST, EUREKA, ESF etc 

Promoting the ETP:

Gaining the support of all European stakeholders  

Organising national and regional consultations:

Ensuring that the SRA addresses the needs and opportunities of all of Europe

Developing Scenario Studies

Raising awareness of long-term challenges and opportunities for the food chain.

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