Transcript Slide 1

NIHR Dementia Research Workshop
NIHR Programme Grants for Applied
Research
Professor Adrian Grant
Programme Director
14 January 2011
Programme Grants
Background
• Support programmes of research rather than individual studies
• Individual awards for a maximum of £2m over up to five years
(average of no more than £400k per year)
• Funding is made to an NHS Organisation in England working in
collaboration with appropriate academic partners
• Two-stage assessment process
• Applications and post-award processes managed by team at the
NIHR Central Commissioning Facility (NIHR CCF)
Programme Grants
Purpose
• Support top quality, collaborative, multidisciplinary teams
• ‘Downstream’, applied research
• Collection of inter-related research activities
• Coherent ‘stream’ of work, where the whole is greater than sum of
the individual parts
• Often presented as workpackages, subdivided into discrete activities
Programme Grants
Some currently funded programmes:
• Dementia care in the community
Prof Steve Iliffe, Central & North West London NHS Foundation Trust
• Support at home through psychological and social interventions
Prof Martin Orrell, North East London NHS Foundation Trust
• Optimizing care in care homes
Prof Clive Ballard, Oxfordshire & Buckinghamshire Mental Health
NHS Foundation Trust
• Managing challenging behaviour in dementia
Prof Esme Moniz-Cook, Humber Mental Health Teaching NHS Trust
• Preventing acute confusional illness
Prof John Young, Bradford Teaching Hospitals NHS Foundation Trust
Programme Grants
Selection criteria
• Track record and appropriate mix of skills
• Relevance to priorities and needs of the NHS
• Likelihood of significant benefit to patients and the NHS within 35 years of programme’s end
• Quality of the proposed research
• Value for money
Patient and Public Involvement given particular attention
Programme Grants
Further information
• Fuller details are on the website:
www.pgfar.nihr.ac.uk
• Enquires are welcomed:
The Programme Grants stand in the market place
E-mail:
[email protected]
Telephone: 020 8843 8039
Address:
NIHR CCF
Grange House
15 Church Street
Twickenham, TW1 3NL
NIHR Dementia Research Workshop
NIHR Research for Patient Benefit
Professor David Armstrong
Programme Director
14 January 2011
The RfPB Programme
• Response-mode funding programme with a budget
of £25m per year
• Project grants may be:
• Up to 36 months in duration
• Up to £250k
• Three competitions per year
• National Programme with ten
Regional Funding Committees
• Open to researchers in the NHS in
England
The RfPB Programme
• Supports high quality investigator-led research
projects which have a clear trajectory into patient
benefit
• Includes qualitative or quantitative research which:
– Studies the way the NHS services are provided and
used
– Evaluates whether interventions are effective and
provide value for money
– Supports pilot or feasibility studies leading to major
applications to other NIHR funding streams
The Application Process
•
•
•
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One stage application process
Preliminary scrutiny and administrative sift
External peer and lay review
Full assessment by one of ten regional
funding committees
• Final ratification
• Notification of outcome
The Scrutiny Stage
Three questions will be asked:
• Is the proposal likely to lead to patient
benefit?
• Is the presentation and/or methods
appropriate for the research question?
• Is the application form completed
according to the instructions described in
the guidance?
Research for Patient Benefit
Spend across health category
(2009-2010)
Generic Health
Relevance
15%
BLOOD
CANCER
Cancer
7%
CARDIOVASCULAR
CONGENITAL DISORDERS
EAR
EYE
INFECTION
Stroke
6%
INFLAMMATORY
INJURIES
MENTAL HEALTH
METABOLIC AND ENDOCRINE
MUSCULOSKELETAL
Mental Health
19%
Reproductive
8%
NEUROLOGICAL
ORAL AND GASTRO
OTHER
RENAL AND UROGENITAL
REPRODUCTIVE
RESPIRATORY
Oral & Gastro
7%
SKIN
Neurological
6%
STROKE
GENERIC HEALTH
RELEVANCE
Research for Patient Benefit
Dementia call
• Essentially will use existing processes
(Scrutiny Committee, scientific and lay review,
Regional Funding Committee appraisal)
• Will alert all Regional Committees of the Call
and advise them of the strategic need to fund
applications in this area, subject to quality
thresholds
• Will participate with other Programmes in
cross-referring applications
• For more information, visit
www.rfpb.nihr.ac.uk
• Or call the RfPB helpline
0208 843 8057
NIHR Dementia Research Workshop
NIHR Evaluation Trials and Studies
Programmes
Professor Tom Walley, CBE
Director: NIHR Evaluation Trials and Studies
14 January 2011
INVENTION
EVALUATION
ADOPTION
DIFFUSION
Basic Research
Development Pathway Funding
MRC
Efficacy & Mechanism Evaluation
Invention for Innovation
Biomedical Research Centres
National Institute
for Health Research
Biomedical Research Units
Patient Safety and Quality
Research Centres
Research for Innovation,
Speculation & Creativity
Research for Patient Benefit
Health Services Research
Programme Grants for
Applied Research
Public Health Research
This pathway covers the full range of
interventions - pharmaceuticals, biologicals,
biotechnologies, procedures, therapies and
practices - for the full range of health and health
care delivery - prevention, detection, diagnosis,
prognosis, treatment, care.
Service Delivery & Organisation
Health Technology Assessment
Collabs for Ldrshp in Appl Hlth Res and Care
Ctr for Reviews & Dissemination, Cochrane, TARs
NHS Purchasing & Supplies Agency
Centre for Evidence-based Purchasing
Guidance on Health & Healthcare
National Institute for Health & Clinical Excellence
NHS Evidence
Access to Evidence
NHS Institute for Innovation & Improvement
Support for the NHS
Strategic Health Authorities
Duty of Innovation
Primary Care Trusts Healthcare Commissioning
NHS Providers
Patient Care
NIHR Evaluation, Trials and Studies
(NETS) programmes
Service Delivery
& Organisation
Established: 1999
Health Technology
Assessment
NETSCC: Established: 2008
Health Services
Research
Established: 2008
Public Health
Research
Established: 2008
Established: 1993
Efficacy and
Mechanism
Evaluation
Funded by the MRC
Managed by NIHR
Established: 2008
Efficacy and Mechanism
Evaluation programme
•
Purpose and Remit
The EME programme is aimed at supporting ‘science driven’ studies with an
expectation of substantial health gain.
•
The EME programme works seamlessly with and sits between MRC
programmes and the HTA programme
Types of
Research
Researcher-led
Primary Research
addressing efficacy
+/- mechanism
Who defines
the question?
Researcher
Frequency
Per year
Continuous with
3 submission
deadlines
NIHR Health Technology
Assessment programme
•
Purpose and Remit
To deliver information about the effectiveness, costs and broader impact of
healthcare treatments and tests for those who plan, provide or receive care in
the NHS.
Types of
Research
Primary research
Feasibility & pilot
Evidence synthesis
Commissioned
Who defines
the question?
Frequency
Per year
HTA programme
4 calls
Primary research
Clinical
Feasibility & pilot
Researcher
evaluation Evidence synthesis
Researcher Led
Themed CallsPrimary research
Evidence synthesis
NICE Guidance
Specific technology
assessment
Continuous with
4 closing dates
Theme from HTA
programme
Question from
researcher
1 call
NICE
Direct referral to
On-contract teams
HTA Studies currently underway in dementia
• Reminiscence groups for people with dementia and their family
care-givers
Professor R Woods, University of Wales
2007-11 £1,536,391
• HTA study of antidepressants for depression in dementia
(HTA-SADD)
Professor S Banerjee
The Institute of Psychiatry, 2006-11 £2,210,588
• Individual Cognitive Stimulation Therapy for dementia
(iCST Trial)
Professor Martin Orrell, UCL,
2010-14 £1,213,646
HTA Studies currently underway in dementia
• Effectiveness and cost effectiveness of Collaborative cARE for
people with DEMentia in primary care (CARE-DEM trial)
Professor S Iliffe, UCL
2010-15 £2,315,251
• The START (STrAtegies for RelaTives) study: to determine the
effectiveness of a manual based coping strategy programme in
promoting the mental health of carers of people with dementia
Professor G Livingston UCL
2009-13 £1,521,781
NIHR Service Delivery and
Organisation Programme
•
Purpose and Remit
Produces research about the organisation and delivery of healthcare for NHS
leaders and decision-makers, commissioners, providers of health care,
partner organisations such as local authorities and the voluntary sector, and
for users of health care. This evidence is intended to improve practice in
relation to the organisation and delivery of healthcare.
Types of
Research
Priority Areas
Commissioned
Researcher-led
Who defines
the question?
Primary research
Evidence synthesis SDO programme
Empirical studies
NHS
Primary research
NHS Evaluations
Evidence synthesis SDO programme
Researcher
Evaluations
SDO Studies
Primary research
Evidence synthesis Researcher
SDO Studies currently underway in dementia
• Better mental health care for older people in general hospitals
Professor J Gladman, Nottingham
2008-11 £473,487
NIHR Public Health
Research programme
•
Purpose and Remit
The PHR programme evaluates public health interventions, providing new
knowledge on the benefits, costs, acceptability and wider impacts of non-NHS
interventions intended to improve the health of the public and reduce
inequalities in health.
The scope of the programme is multi-disciplinary and broad covering a range
of public health interventions.
Types of
Who defines
Frequency
Commissioned
Researcher-led
Research
the question?
Non-NHS
Primary research
Evidence synthesis
PHR programme
As required
Non-NHS
Primary research
Evidence synthesis
Researcher
Continuous with
3 closing dates
Per year
NIHR Health Services
Research programme
•
Purpose and Remit
The HSR programme funds research to improve the quality, effectiveness and
accessibility of the NHS.
The HSR programme addresses the three dimensions of quality currently of
central concern to the NHS: patient safety, patient experience and
effectiveness of care.
Researcher-led
Types of
Research
Who defines
the question?
Any study
design
Researcher
Frequency
Per year
Twice yearly
NETS as a system
Facilitating researchers,
speeding review
Transfers between NETS
programmes
Active collaboration
between programmes
Directors' meetings
Joint calls
Meeting with networks
Keele
Keele
Support for CTUs
25 (in England)
now supported by
HTA programme
“pump-priming”
• Major new opportunity for funding research
into dementia
– NETS programmes focused on projects with
national reach
– Multicentred
– Trials and other designs
(Engaging with CTUs)
NIHR Dementia Research Workshop
For further information, please visit:
www.nihr.ac.uk/research/Pages/Dementia.aspx
14 January 2011
National Institute for Health Research
Dementia Research Workshop
14 January 2011