Transcript שקופית 1 - IBRWEB HOME

Colorless Carotenoids Combinations
TiO2 & ZnO
CoQ10
Carotenoids
DHA
DiHydroxy
Acetone
Omega 3 oils
DHA & EPA
Colorless Carotenoids:
Phytoene & Phytofluene
Squalene
Efficacy
Protection and Stability
Synergism
Boosting activity
Vitamin C
IBR-Dormin®
www.ibrweb.com
Retinol
©
Colorless Carotenoids Combinations
TiO2 & ZnO
Carotenoids
Omega 3 oils
DHA & EPA
Colorless Carotenoids:
Phytoene & Phytofluene
Squalene
Efficacy Protection and
Stability Synergism
Boosting activity
Vitamin C
Phytoene and phytofluene
•Beauty from the inside* and outside
CoQ10
• Anti aging and photo-aging
• Skin brightening/whitening – evening of
skin tone
• Protection
DHA against UV and its damage
DiHydroxy
• Anti
oxidant
Acetone of DNA damage
• Prevention
• Anti inflammatory
• Protection and enhancement of other
active ingredients and their activity
IBR-Dormin ®
www.ibrweb.com
Retinol
©
Colorless Carotenoids Combinations
TiO2 & ZnO
CoQ10
Carotenoids
DHA
DiHydroxy
Acetone
Omega 3 oils
DHA & EPA
Colorless Carotenoids:
Phytoene & Phytofluene
Squalene
Efficacy Protection and
Stability Synergism
Boosting activity
Phytoene and phytofluene –
TiO2 & ZnO
•Stabilization
•Boost of SPF*
•Reduce generation of free radicals
and damage derived from
irradiation of TiO2 & ZnO
UV filter
SPF in
vitro
Phytoene 5%
15.2
Retinol
TiO2 5%
Phytoene 2.5%
+ TiO2 2.5%
Predicted
SPF
Increase
8.3
94%
1.3
16.0
* SPF in vitro : the average of five measurement
Vitamin C
IBR-Dormin ®
www.ibrweb.com
©
Colorless Carotenoids Combinations
CoQ10
Carotenoids
DHA
DiHydroxy
Acetone
Omega 3 oils
DHA & EPA
45
40
35
30
Colorless Carotenoids:
Phytoene & Phytofluene
Squalene
Efficacy Protection and
Stability Synergism
Boosting activity
25
20
Retinol
15
10
% Phenol after UVA irradiation
TiO2 & ZnO
Phytoene and phytofluene –
TiO2 & ZnO
•Stabilization
•Boost of SPF
•Reduce generation of free radicals
and damage derived from
irradiation of TiO2 & ZnO*
5
0
TiO2+0.05 mg/ml P&P
Vitamin C
IBR-Dormin ®
TiO2+0.01 mg/ml P&P
* UVA irradiated phenol stability
www.ibrweb.com
0.25% TiO2
©
Colorless Carotenoids Combinations
TiO2 & ZnO
CoQ10
Carotenoids
DHA
DiHydroxy
Acetone
Omega 3 oils
DHA & EPA
1.
Phytoene & phytofluene – CoQ10
•Stabilization and protection against
degradation
•Synergism:
1. Anti aging - reduced MMP-1
expression*
2. Reduced inflammation – PGE-2*
•Anti oxidants – reduce fatigue & stress
2.
Colorless Carotenoids:
Phytoene & Phytofluene
Squalene
Efficacy Protection and
Stability Synergism
Boosting activity
Vitamin C
Retinol
*Fuller B.B., et al. J. Cos. Der.. 2006 March. 5(1):30
IBR-Dormin ®
www.ibrweb.com
©
Colorless Carotenoids Combinations
Phytoene & phytofluene – Retinol
TiO2 & ZnO
CoQ10
Carotenoids
•Stabilization and protection against degradation
A. 5% Retinol + 0.5% Phytoene & Phytofluene
B. 0.1% Retinol+0.05% Phytoene & phytofluene
DHA
DiHydroxy
Time: 0
Acetone
Omega 3 oils
DHA & EPA
Time: 10 min
A
A
Colorless Carotenoids:
Phytoene & Phytofluene
Squalene
Efficacy Protection and
Stability Synergism
Boosting activity
Vitamin C
Retinol
B
Retinol left in cream after 4 weeks with
0.5% IBR-Dormin
Phytoene ®& Phytofluene or
0.05% BHT
93%
68%
www.ibrweb.com
B
©
Colorless Carotenoids Combinations
Phytoene and phytofluene – b-carotene
TiO2 & ZnO
CoQ10
Carotenoids
•Stabilization and protection against degradation
•IBR-AAC® Anti Aging Carotenoids – phytoene,
phytofluene and β-carotene: anti oxidation, anti
inflammation, UV protection and pro-retinol
addition
DHA
Omega 3 oils
DHA & EPA
Starting point
DiHydroxy
After 35 minutes sun and air exposure
Acetone
Colorless Carotenoids:
Phytoene & Phytofluene
Squalene
Efficacy Protection and
Stability Synergism
Boosting activity
Vitamin C
Retinol
IBR-Dormin ®
www.ibrweb.com
©
Colorless Carotenoids Combinations
Phytoene and phytofluene – Omega 3 oils
TiO2 & ZnO
Stabilization and protection against
degradation
CoQ10
Carotenoids
Reduce peroxide number
•
Combined activities:
1. Prevention of LDL oxidation
2. Anti aging- anti oxidants, anti
DHA
inflammatory and protection from UV
Omega 3 oils
DiHydroxy
DHA & EPA
Acetone
damage
3. Reduced stretch marks and wrinkles
via combined activity of induction of old
Colorless Carotenoids:
collagen degradation and
Phytoene & Phytofluene
enhancement of new collagen
Efficacy Protection and
Stability Synergism
Retinol
synthesis (mostly due to phytoene and
Squalene
Boosting activity
phytofluene benefits)
4. Skin protection
Vitamin C
•
IBR-Dormin ®
www.ibrweb.com
©
Colorless Carotenoids Combinations
Phytoene and phytofluene – squalene
TiO2 & ZnO
•
Stabilization and protection against degradation
Reduction in peroxide number
CoQ10
•
Activities:
1. Squalene boosts the phytoene and
phytofluene protection against UVA and
UVB and UV damage in general
DHA2. Anti aging- via anti oxidation and protection
DiHydroxy from UV damage
Carotenoids
Omega 3 oils
DHA & EPA
Acetone
Effect of phytoene & phytofluene and squalene
on % peroxides formed in EPA exposed to air
Colorless Carotenoids:
120
Phytoene & Phytofluene
60
40
www.ibrweb.com
Squalene
5% +
0.0025%
algal PH
Squalene
5% +
0.005%
algal PH
Squalene
5% +
0.01%
algal PH
Squalene
5%
0.0075%
tomato
PH and PF
0.0037%
tomato
PH and PF
0.01%
algal PH
and PF
0
IBR-Dormin ®
0.005%
algal PH
and PF
20
5%
SQULENE
Vitamin C
Retinol
EPA
% Peroxide created
Squalene
100
Efficacy Protection and
Stability Synergism
80
Boosting activity
©
Colorless Carotenoids Combinations
Phytoene and phytofluene – IBR-Dormin®
TiO2 & ZnO
CoQ10
Carotenoids
Omega 3 oils
DHA & EPA
Colorless Carotenoids:
Phytoene & Phytofluene
Squalene
Efficacy Protection and
Stability Synergism
Boosting activity
Vitamin C
•
Complementary short and long term anti aging
action
Colorless carotenoids- anti oxidants, UV and UV
damage protectors, collagen balancing (old
DHA and new), prevention of damage to DNA.
IBR-Dormin® - slowing down aging via dormancy
DiHydroxy
Acetone and slowdown of cell proliferation.
•
Combined skin whitening/ brightening activity.
Inhibition of melanocytes proliferation and
melanin synthesis
Retinol
IBR-Dormin ®
www.ibrweb.com
©
Colorless Carotenoids Combinations
Phytoene and phytofluene – vitamin C
TiO2 & ZnO
CoQ10
Carotenoids
Omega 3 oils
DHA & EPA
Colorless Carotenoids:
Phytoene & Phytofluene
Squalene
Efficacy Protection and
Stability Synergism
Boosting activity
Vitamin C
•
•
Mutual stabilization in emulsions
Activities:
1. Combined skin whitening/
brightening activity.
DHA
DiHydroxy2. Oil soluble and water soluble anti
oxidants combination
Acetone
3. Reduced stretch marks and wrinkles
via combined activity of induction of
old collagen degradation and
enhancement of new collagen
Retinol
synthesis
IBR-Dormin ®
www.ibrweb.com
©
Colorless Carotenoids Combinations
TiO2 & ZnO
Phytoene and phytofluene –
DHA (di hydroxy acetone)
CoQ10
Carotenoids
DHA
DiHydroxy
Acetone
Omega 3 oils
DHA & EPA
•Stabilization and protection
against degradation
•Anti oxidants – extending
artificial sun tan
Colorless Carotenoids:
Phytoene & Phytofluene
Squalene
Efficacy Protection and
Stability Synergism
Boosting activity
Vitamin C
Retinol
IBR-Dormin ®
www.ibrweb.com
©
Colorless Carotenoids Combinations
Contact
TiO2 & ZnO
Business Development and Marketing:
CoQ10
Carotenoids
Liki von Oppen-Bezalel, Ph.D.
Hartmannsweilerweg 1, 14163 Berlin, Germany
Tel: +49-30-80589698; Fax: +49-30-80589704
email: [email protected]
DHA
DiHydroxy
Office:
Acetone
Omega 3 oils
DHA & EPA
Inon Perry, CEO
Colorless Carotenoids:
Phytoene & Phytofluene
Squalene
Efficacy Protection and
Stability Synergism
Boosting activity
Vitamin C
7 Jabotinsky st., Ramat-Gan 52520, Israel
Tel:+972-3-5165432; Fax:+972-3-5165654
Retinol
email: [email protected]
IBR-Dormin ®
These statements have not been evaluated by the Food and Drug Administration.
These products are not intended to diagnose, treat, cure or prevent any disease
www.ibrweb.com
©