Transcript Introducing a New Product

Dr. Ariel Weisz
R&D Department
Metrolab, Argentina
Distributor Meeting
MEDICA
November, 2009
Metrolab is a company which designs and manufactures
Clinical Chemistry Analyzers with its own technology.
+ reliable instruments to the global market
+ easy of use
+ effective after-sale service
+ competitive prices
Clinical Chemistry Analyzers
The Principle: Spectrophotometry
Absorbance
Beer-Lambert Law
T = P / P0
A = log10(P0 / P)
A = elbc
concentration
el: molar absorbtivity
c: molar concentration
Colorimetry
Reagents
Samples
Reactions
Mix
Incubation
(37°C)
Measure
Double beam photometer
beam
splitter
reaction
cuvettes
sample
detector
lamp
filter
S
R
A = log(R/S)
reference
detector
Dual photometer
R
reference
detector
Back sample
detector
lamp
filter
AF = log(R/SF)
AB = log(R/SB)
beam
splitters
SB
SF
Front sample
detector
Clinical Chemistry Analyzers
Applications and Measuring Methods
One Reagent End Point
Absorbance
A
B
R1+S
Time
Measure = A - B
Metabolites
Albumin
Glucose
Cholesterol
Uric acid
Triglycerides
Total proteins
Two-Reagent End Point
Absorbance
A2
A1
B2
B1
R1+S
R2
Time
Measure = (A2-A1) – (B2-B1)
Bilirubin
IgA, IgG, IgM
LDL, HDL
Phosphorous
Fixed Point Kinetics
Absorbance
A2
A1
B2
B1
R1+S
Time
Measure = (A2-A1) – (B2-B1)
ALP
Creatinine
Fructusamine
Urea
Kinetics
Absorbance
An
A1
B1
R1+S
Bn
Time
Measure = rateA – rateB
Enzymes
Amylase
CK, CPK
GGT
GOT
GPT
Clinical Chemistry Analyzers
METROLAB Instruments
// Metrolab history
305
330
315
1985
1600 PLUS
1990
2100
1995
1600 DR
1600 DRK
2300
4000
2000
2005
// Current Line - Main Instruments
60-250+ patients/day
600 test/hr
600
test/hr
20-60+ patients/day
280 test/hr
400
M4000
10-40 patients/day
240 test/hr
200
semiautomatic
M2300v4
M2300GL
M1600DRv3
small labs
veterinary
medium labs
big labs / hospitals
Clinical Chemistry Analyzers
METROLAB 4000
Troughput: 550 test/hr without ISE
• 600 test/hr single reagent
• 450 test/hr double reagent
• 720 test/hr with ISE
Split reagent trays for effective carryover
and interference control
Methods are distributed, at operator’s
will between two trays.
In this way, interfering methods never
come into contact in the same cuvette
Continuous sample load
with coded sectors
Positions can be assigned to normal
samples or STATS,
Handling priorities accordingly
Positive BCR identification of samples,
reagents and sectors
• Coded sectors for instantaneous load
• Any coding system for samples
• Coded reagents and optional closed system
• Open channel support
Optional ISE module: Na+, K+, Cl-
• Direct serum readings
• Indirect urine readings (dilution 1:10)
• Integrated pack for simple operation
• Automatic electrode conditioning
User friendly software with different access levels
Menu bar
Main operation
control tool bar
Quick keys menu
Current activity
and summary
Test in progress
Requests to
operator bar
Reagents status
report
Messages list
General status bar
Mixer in probe
• High efficiency mixing guarantees reliable data in
double reagent systems and viscous media
• Shake time can be programmed for every method
72 on board cooled single reagents
Full size 70 ml
Outer 30 ml
R1 40ml
R2 30 ml
LIS Interface Connection - Customized Reports
PC
Monitor
LIS
Metrolab 4000
PC
ASTM
Standard serial connection
Monitor
Data Management System
Low Water Consumption
4 mL / test
// Current Line - Main Instruments
60-250+ patients/day
600 test/hr
600
test/hr
20-60+ patients/day
280 test/hr
400
M4000
10-40 patients/day
240 test/hr
200
semiautomatic
M2300v4
M2300GL
M1600DRv3
small labs
veterinary
medium labs
big labs / hospitals
Clinical Chemistry Analyzers
METROLAB 2300 PLUS version 4
Version 4
FULLY AUTOMATIC RANDOM ACCESS CLINICAL ANALYZER
• End Point
• Kinetics
• Immunoturbidimetry
• Coagulation
• ISE
• Barcode: Samples & Reagents
• Automatic Sample Dilution
• Mixer on Probe
• Quality Control
Version 4
Samples
• 48 positions for primary tubes,
tubes 75 to 100 mm (Ø 13 mm),
accepts microtainers.
• Positive BCR identification of samples
• Test request through LIS
Version 4
Reagents
• 48 positions cooled reagent
• Bar code for reagents
• Dual reagent capability
• 50, 30 and 20 mL containers
• 24 hours non stop cooling
Version 4
Cuvette washing system
• 4-Step washing station
• Automatic cuvette check
• 6 mm light path PMMA cuvettes
Version 4
Multifunction probe
• Mixer on probe
• Collision detector
• Capacitive liquid level detection
• Effective probe washing
Version 4
Optical system
• Double beam
• 9 interference filters:
340, 405, 505, 550, 590, 650, 700 and 767 nm.
• Optional filters available (380 and 620 nm )
Version 4
Software
• User friendly
• Flexible
• Designed for the clinical analyst
• Continuous upgrade meeting your requirements
Version 4
Easy service
• Open cabinet with only 4 screws
• Calibration through PC
// Current Line - Main Instruments
60-250+ patients/day
600 test/hr
600
test/hr
20-60+ patients/day
280 test/hr
400
M4000
10-40 patients/day
240 test/hr
200
semiautomatic
M2300v4
M2300GL
M1600DRv3
small labs
veterinary
medium labs
big labs / hospitals
Clinical Chemistry Analyzers
METROLAB 2300 GL
METROLAB 2300 GL
Easy service
• Calibration through PC
• No cooling system
• No washing system
• No BCR
• No ISE
METROLAB 2300 GL
Quick cuvette load
• Simple and Fast
• Double tray
• One tray in use (80 cuvettes)
• Preloaded tray ready to use
Clinical Chemistry Analyzers
Common Hints
Clinical Chemistry Analyzers
Common Hints
• Pipetting principle
• Semi-disposable plastic cuvettes
• Low water consumption
• Probe technology
• Line style
Clinical Chemistry Analyzers
Common Hints
• Proprietary Technology
• Proprietary software
• Open or closed customized systems
• Dedicated after-sales service
Clinical Chemistry Analyzers
Next Steps…
• Modular electronics
• Reduce manufacturing costs
• Standardization
Clinical Chemistry Analyzers
Thank you for your attention !!!