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Upper Rate Behavior Why do we have Upper Rate Responses? Reduce incidence of tracking inappropriate rhythm and/or rate for internal use only Upper Rate Response Initiating Factors Exercise Sinus Tachycardia Atrial Arrhythmia Sensing of Myopotentials VA conduction exceeding PVARP for internal use only Upper Rate Response Limit Fastest Atrial rate at which consecutively paced ventricular complexes maintain 1:1 synchrony • Also known as: • Ventricular Maximum Rate (VMR) • Maximum Tracking Rate (MTR) for internal use only Max Track Rate / Max Sensor Rate Definitions • The Max Track Rate, or Maximum Tracking Rate, is the fastest rate that intrinsic P-waves can be tracked, or followed by paced Ventricular events with a 1:1 ratio. • The Max Sensor Rate, is the fastest rate the atria and the Ventricles can be paced, based upon sensor input. for internal use only DDD Timing AVI PV PVARP Atrial Channel PVAB Ventricular Channel BL VRP URI for internal use only Max Track Rate • The fastest rate the Ventricular channel can pace when tracking intrinsic P-waves. for internal use only Max Track Rate Programmed settings should be based on • Patient activity levels • Age (220 – age) • LV function • Chest pain • Tolerance by the Patient if a PMT occurs for internal use only Max Track Rate Questions to consider • Can the programmed Max Track Rate be tolerated by the patient for prolonged periods? • During sinus tachycardia, can a sudden drop in the pacing rate be tolerated? for internal use only Upper Rate Behaviors Fixed-Ratio block/Multiblock (2:1, 3:1, etc) Wenckebach behavior (Pseudo, Electronic) Auto Mode Switch (not in this presentation) for internal use only Upper Rate Behaviors Depends on programmed values: • Max Tracking Rate • Sensed AV Delay • PVARP for internal use only Upper Rate Behavior Fixed Ratio Block Fixed-Ratio Block (Multiblock) Fast Upper Rate Response Simplest way to control upper rate • TARP = MTR AV PVARP TARP (Total Atrial Refractory Period) for internal use only Fixed-Ratio Block 2:1 Block (one v-paced event per two p-waves) MTR = 115bpm AVD = 160ms PVARP = 360 ms for internal use only Fixed-Ratio Block Calculation • 60,000 / TARP: e.g. 60,000 / 440 ms (2:1 block point) = 136 BPM PV PVARP 160 ms + 280 ms TARP = 440 ms for internal use only Fixed-Ratio Block PV interval always remains constant May be inappropriate in young or physically active patients due to sudden rate drops Patient tracks P-waves until the atrial rate gets to the 2:1 block • The Ventricular rate will suddenly go to half the Atrial rate for internal use only Fixed-Ratio Block Fall Down Rate for internal use only 2:1 blocking Stimulated ventricular rate Ex.: Shipped Settings PV Delay 150 ms PVARP 275 ms 2:1-blockpoint 142 min-1 160 140 120 100 80 60 Sensed Atrial Rate 80 for internal use only 100 120 140 160 Upper Rate Responses Wenckebach Upper Rate Behavior Wenckebach block Do you remember? AV Block 2nd degree Mobitz I for internal use only Wenckebach Max Track (MTR) must be programmed slower than the TARP interval 2:1 fixed-ratio block will occur when the P-P intervals become faster than TARP for internal use only Wenckebach Ap Vp Ap Vp Vp P P P P Base Rate Interval AV AV PV V-A Interval PVARP MTR TARP W-Period for internal use only Wenckebach behaviour Look at the VV and AV intervals for internal use only Wenckebach Provides a smoother transition from 1:1 to 2:1 block Avoids a sudden reduction of the ventricular pacing rate and maintains some degree of AV synchrony for internal use only Wenckebach Wenckebach response to increasing Atrial rates Wenckebach Plateau Ventricular Rate (paced) 2:1 Lower Rate MTR Atrial Rate (sensed) for internal use only 3:1 1:1 TARP .. ..... ARRP Wenckebach Example • DDD • MTR 100 bpm (600 ms) • AV delay 150 ms • PVARP 250 ms • TARP150 + 250 = 400 ms \150ppm • Therefore, atrial rates >100 bpm (600 ms) but < 150 bpm will result in Wenckebach behavior • Max PV delay prolongation is 200 ms (600-400) • PV intervals will vary from 150 - 350 ms for internal use only Wenckebach Calculation to determine if a Wenckebach is present: • Programmed MTR minus TARP • In our example: 600 ms - 400 ms = 200 ms • We have a 200 ms Wenckebach window for internal use only Atrial Rate Continuum Base Rate MTR AV delay PVARP 60 130 170 250 PPM PPM MS MS 60 PPM Base Rate Device Response 130 PPM (MTR) 1:1 Tracking 143 PPM TARP Wenckebach TARP = PV Delay + PVARP = 170 + 250 = 420 ms 143 PPM (2:1 Block Point) for internal use only 2:1 Block Wenckebach Ap Vp Ap Vp Vp P P P P Base Rate Interval AV AV PV 150 ms V-A Interval PVARP MTR 600 ms TARP W-Period for internal use only 200 ms Pseudo Wenckebach - Upper Rate Behaviour A-A AV Delay PVARP VRP MTRI Maximum Tracking Rate Interval for internal use only Wenckebach Base Rate MTR AV PV Min. PV PVARP for internal use only 60 ppm 120 ppm 200 ms 150 ms 88 ms 250 ms Wenckebach P-wave in alert and sensed AVPVARP PVARP MTR MTR PVARP MTR PVARP MTR PVARP MTR PVARP MTR PVARP MTR AV PVARP MTR PVARP PVARP MTR Ventricular pacing at Max Tracking Rate Base Rate MTR AV PV Min. PV PVARP for internal use only 60 ppm 120 ppm 200 ms 150 ms 88 ms 250 ms MTR AV PVARP MTR PVARP MTR AV PVARP Wenckebach Identification • Variable PV delays • Sustained high rate pacing • Occasional change in the beat to beat ventricular rate • Long PV intervals may initiate an endlessloop Tachycardia for internal use only Wenckebach and MTR Stimulated ventricular rate 160 140 TARP 120 = Max. Tracking Rate 100 80 60 Sensed Atrial Rate 80 for internal use only 100 120 140 160 Upper Rate Responses Fixed-ratio Block Wenckebach PV Delay constant AV Delay progressively lengthens Pauses in pacing operation may be seen for internal use only AMS AV Delay constant until DDI(R) pacing occurs at the AMS base rate 2:1 blocking Stimulated ventricular rate Ex.: Shipped Settings PV Delay 150 ms PVARP 275 ms 2:1-blockpoint 142 min-1 160 140 120 100 80 60 Sensed Atrial Rate 80 for internal use only 100 120 140 160 Factors Limiting Upper Rate P V PV Delay Programmed PV Delay Rate Resp. AV/PV Delay Shortest AV/PV Delay for internal use only PVARP Programmed PVARP Rate Resp. PVARP/VRP Shortest PVARP/VRP Rate Responsive AV Delay To mimic normal heart function 70 min-1 Spontaneous PR interval reduction Tracking with RRAVD enabled for internal use only 110 min-1 130 min-1 Rate Responsive AV/PV Delays and Shortest AV/PV Delay 200 150 100 Low, 1 ms min-1 Medium, 2 ms min-1 High, 3 ms min-1 for internal use only 195 190 185 180 175 170 165 160 155 150 145 140 135 130 125 120 115 110 105 100 95 0 90 50 Rate Responsive AV/PV Delays… … and Shortest AV/PV Delay 200 150 100 Low, 1 ms min-1 Medium, 2 ms min-1 High, 3 ms min-1 for internal use only 195 190 185 180 175 170 165 160 155 150 145 140 135 130 125 120 115 110 105 100 95 0 90 50 2:1 blocking and RRAVD Stimulated ventricular rate Ex.: Shipped Settings PV Delay 150 ms PVARP 275 ms With RRAVD 160 140 120 (Low, Medium and High) 100 80 60 Sensed Atrial Rate 80 for internal use only 100 120 140 160 Rate Responsive Refractory Periods PVARP VRP Low, 1 ms min-1 Medium, 2 ms min-1 High, 3 ms min-1 for internal use only Rate Responsive Refractory Periods PVARP VRP Low, 1 ms min-1 Medium, 2 ms min-1 High, 3 ms min-1 for internal use only Rate Responsive Refractory Periods PVARP VRP Low, 1 ms min-1 Medium, 2 ms min-1 High, 3 ms min-1 for internal use only Rate Responsive Refractory Periods PVARP VRP Low, 1 ms min-1 Medium, 2 ms min-1 High, 3 ms min-1 for internal use only Pseudo Wenckebach Upper Rate Behaviour MTR Intervall for internal use only MTR Intervall MTR Intervall MTR Intervall 2:1 blocking and MTR Stimulated ventricular rate 160 140 = Max. Tracking Rate Programmed MTR, too high. Will not limit the rate fall at 2:1 block rate. 120 100 80 60 Sensed Atrial Rate 80 for internal use only 100 120 140 160 2:1 blocking Stimulated ventricular rate 160 140 = Max. Tracking Rate = Max. Sensor Rate 120 = Sensor Indicated Rate Use of a well tailored sensor will relieve the problems of a high MTR 100 80 60 Sensed Atrial Rate 80 for internal use only 100 120 140 160 Summary One to One tracking is the best upper rate behavior When tracking at this rate is inappropriate, the device may be programmed to exhibit: • Fixed Ratio Block (Multiblock) • Wenckebach • RR AV delay – PVARP/VRP • DDIR • Auto Mode Switch for internal use only Summary When programming • AV delay • PVARP • Max Tracking Rate Remember • Wenckebach AVD + PVARP < MTR • 2/1 block (mentioned on Merlin) AVD + PVARP = MTR for internal use only Merlin for internal use only Upper Rate Behavior Questions