Transcript Think Foot-and-Mouth Disease when you see

Think Foot-and-Mouth Disease
when you see…
Texas A&M University
College of Veterinary Medicine
Jeffrey Musser DVM, PhD, DABVP
Suzanne Burnham, DVM
Blisters and
Excess Salivation
Foot-and-Mouth Disease
Click image to start movie
Foot-and-Mouth Disease
Think Foot-and-Mouth Disease
when you see…
Foot-and-Mouth Disease
Think foot-and-mouth
disease when you see cattle
with excessive salivation
Foot-and-Mouth Disease
Foot-and-Mouth Disease
Image courtesy of Dr Tom McKenna
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P T Hooper
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FAO
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Lesions in cattle
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Blisters on the tongue
Day One
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Blisters on the tongue
Blister on bovine tongue
http://www.fao.org/Regional/LAmerica/prior/segalim/animal/aftosa/default.htm
Foot-and-Mouth Disease
Blisters become erosions
Day
Four
Salivation increases as vesicles form and
rupture. Symptoms increase in intensity.
Foot-and-Mouth Disease
Blisters become erosions
Day
Four
Day
Six
Salivation increases as vesicles form and
rupture. Symptoms increase in intensity.
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Animals may recover in
2 weeks. Only 1-5%
die from FMD
Days 8-14
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Think Foot-and-Mouth
Disease when you see lame
cattle – look for blisters
between the toes
Foot-and-Mouth Disease
Lameness
•Coronary band lesion
first appears blanched
•Blisters and erosions
form between the digits
•Stamping and shaking
of feet
•Trembling
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Clinical Signs in Cattle
Blisters form on:
Mouth
Feet
Tongue
Dental pad
Gums
Soft palate
Inter-digital space
Coronary band
Teats
Muzzle
Nostrils
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Clinical Signs in Cattle
Rarely fatal except in young
animals
Young calves may die without
showing any clinical signs
Foot-and-Mouth Disease
USDA
In young animals there is focal necrosis
of cardiac muscle. “Tiger heart”
50-80% young infected animals die
Foot-and-Mouth Disease
USDA
Extra-epithelial
replication limited to
myocardium,
immature animals only
USDA
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Recovery Phase
Recovered animals are permanently unthrifty
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Recovery
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Foot-and-Mouth Disease
in Swine
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In Swine
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Pigs –Reluctance to
move, painful toes
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Pigs –Reluctance to move
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Lesions in Swine
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Lesions in Swine
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Lesions in Swine
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Lesions in Swine
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Lesions in Swine
Blisters on teats and udders
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Lesions in Swine
Mastitis
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Clinical Signs in Sheep and Goats
When sheep or goats become
infected with FMD, the disease may
not be diagnosed for a considerable
time because the clinical signs may
be very mild.
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Lame sheep
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Signs in Sheep and Goats
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Signs in Sheep and Goats
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Foot-and-mouth Disease in
sheep
Lameness
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Foot-and-mouth Disease in
Sheep
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Lesions in Sheep
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Lesions in sheep
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Lesions in sheep
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Lesions in giraffe
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Lesions in elephants
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Bibliography
Committee on Foreign Animal Diseases of the United States Animal
Heath Association, “Foreign Animal Diseases” 1992, Ch. Vesicular
Diseases, p. 368-382.
W. A. Geering, et.al, Exotic Diseases of Animals: a field guide for
Australian veterinarians, 1995, Ch Foot-and-mouth disease, p.112131
Ninth Edition of Merck Veterinary Manual
M. Van Vuuren, Foot-and-mouth Disease, an Overview, University of
Pretoria 2005, Presentation given at Knoxville, Tenn. FEAD course.
Thomson, G. R. and Bastos, A. D. S. “Foot-and-mouth disease” Ch 125
of Infectious Diseases of Livestock, Volume 2. Ed. J. A. W. Coetzer
and R. C. Tustin. Oxford University Press, second edition, 2004,
1324-1365.
Foot-and-Mouth Disease
Bibliography
Tomasula, P.M. and R.P. Konstance. “The Survival of Foot-and-Mouth
Disease Virus in Raw and Pasteurized Milk and Milk Products”.
Journal of Dairy Science, 2004; 87:1115-1121.
Callis, J.J. et al. “Foot-and-mouth Disease – A Review”. JAVMA, 1968;
153:12, 1798-1802.
Musser, J.M.B. “A practitioner’s primer on foot-and-mouth disease”.
JAVMA, 2004; 224:8, 1261-1268.
Alexandersen, S., et al. “The Pathogenesis and Diagnosis of Foot-andMouth Disease”. J. Comp. Path. 2003; 129:1-36.
O.I.E.
USDA, APHIS, VS, The Grey Book. And associated websites.
Personal interviews with Dr Logan, Dr McKenna, Dr Coetzer, Dr
VanVuuren and Dr Waldrup
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Acknowledgements
Special thanks to
Linda Logan, DVM PhD
Ken Waldrup, DVM PhD
Robin Sewell, DVM
Kelsey Pohler- Research Assistant
Tom McKenna, DVM PhD
Corrie Brown, DVM PhD
Foot-and-Mouth Disease