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Children’s National Medical Center – NHLBI
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CNMC – NHLBI ICMR Research Team
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Kanishka Ratnayaka, MD
Laura J. Olivieri, MD
Russell R. Cross, MD
Michael S. Hansen, PhD
Kendall J. O’Brien, BA
Karin S. Hamann, RNC
Charles I. Berul, MD
Joshua P. Kanter, MD
Michael C. Slack, MD
Elena Grant, MBChB
Sridhar Hanumanthaiah, MS
Richard J. Levy, MD
Jeffrey P. Moak, MD
Charles R. Fleming, RN, BScN, CPN
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Toni Sego, RCIS
Robert J. Lederman, MD
Anthony Faranesh, PhD
Toby Rogers, MD
Ozgur Kocaturk, PhD
Adrienne Campbell-Washburn, PhD
Hui Xue, PhD
Peter Kellman, PhD
Annette M. Stine, RN
Jonathan Mazal, BSc
Bill Schenke, BSc
Laurie Grant, RN
Merdim Sonmez, PhD
Dominique Franson, BA
ICMR Research Timeline
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• April 2013
CNMC-NHLBI ICMR Suite Open
• May 2013
Diagnostic Pediatric MRI
Research Program Starts
• November 2013
X-Ray Fused with MRI (XFM)
Research Program Starts
• February 2014
MRI guided Electrophysiology
Research Program Start
• March 2014
MRI Heart Catheterization
Research Program Start
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XFM
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MRI
overlay
on live
X-Ray
Fluoro
Display
XFM
Guided,
Novel,
Antegrade
pmVSD
Device
Closure
(Ratnayaka, JACCInter
2008)
Conventional X-ray vs Novel XFM
X-ray
XFM
VSD crossing
286 + 150s
168 + 142s
p=0.01
Sheath
positioning
380 + 193s
74 + 70s
p<0.001
Fluoroscopy
400 + 215s
166 + 134s
P<0.001
2459 + 2335
mGm2
p<0.001
Radiation dose5052 + 2955
area-product
mGm2
(DAP)
X-Ray
XFM
device
closure
XFM
XFM
post
device
closure
CNMC – NHLBI ICMR Next Steps
Radiation Free Cardiac Catheterization
MR Electrophysiology
MR Structural Heart Intervention
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