Transcript NF-149 A New Systemic Fungicide for Control of Powdery Mildew

NF-149
A New Fungicide
for Control of Powdery Mildew
IR-4 Food Use Workshop
Tampa - 2007
NF-149
• NF-149 is a new fungicide for control of a wide range of
powdery mildews on various crops
• New chemical discovered by Nippon Soda Co. Ltd.
• No cross resistance to existing powdery mildew products
– Biochemical MOA not yet defined
• Common name: cyflufenamid
F
F
N
O
N
H
CF 3
O
NF-149
• Powdery Mildew on Grapes
NF-149
• Powdery Mildew on Apples
NF-149
• Powdery Mildew on Cucurbits
NF-149
NF-149
Effect of Cyflufenamid Against Powdery Mildews on Various Crops
(greenhouse screening, minimum inhibitory concentration)
Crop
Pathogen
Wheat
Blumeria graminis f.sp.tritici
Cucumber
Sphaerotheca cucubitae
Strawberry
Sphaerotheca aphanis var. aphanis
Sweet pepper
Oidiopsis sicula
Apple
Podosphaera leucotricha
Persimmon
Phyllactinia kakicola
Grape
Uncinula necator
Rose
Sphaerotheca pannosa
MIC(ppm)
< 0.8
< 0.8
< 0.8
< 0.8
< 1.6
< 1.6
< 1.6
< 1.6
NF-149
Effect of Cyflufenamid Against a Powdery Mildew Strain Resistant to
other Commercial Fungicides (greenhouse screening, minimum inhibitory concentration)
Pathogen
Commercial
fungicide
MIC(ppm)
cyflufenamid
MIC(ppm)
S
< 0.1
< 0.8
R
> 100
< 0.8
S
< 0.1
< 0.8
R
5
< 0.8
S
1
< 0.8
R
> 100
< 0.8
Commercial-----Sensitivity
--fungicides
Sphaerotheca------- kresoxim------------cucubitae
------methyl
triflumizole
thiophanate----------methyl
NF-149
•
Currently registered in Japan, Korea, and the several EU countries
– Cereals, fruiting vegetables, pome fruit, stone fruit
– Favorable toxicological, e-fate, and eco-tox profile
•
Data Submission to US EPA Planned for 2008
•
Initial US formulation: 10% SC
•
Low Use Rate:
•
Planned crops for the US:
12.5 to 25 grams a.i./hectare
(0.011 to 0.022 lb a.i./A or 1.7 to 3.4 oz form./A)
grapes;
pome fruit;
cucurbits;
strawberries;
3 day PHI
14 day PHI
0 day PHI
0 day PHI
NF-149
• Other potential US uses include:
stone fruit
fruiting vegetables
leafy vegetables
cole crops
hops
cane berries
grains
ornamentals