Transcript NSD EQA
Circulation F
Case 85
Female
aged 34, previous gyn surgery.
Painful lump in middle of scar.
?fat necrosis.
Diagnostic category:
1 Endometriosis
Popularity:
10.00
Score:
1.0
Case 86
Male
aged 81.
Cystic lump on the chin enlarging over a
few weeks.
Most popular diagnosis:
1 Metastatic adenocarcinoma (+/- GI)
7.34
Case 87
Female
aged 57.
Breast carcinoma in 2006 treated by
excision and radiotherapy.
Multiple papules and nodules on left
breast
?skin meastases ?angiosarcoma
?radiation injury ?irritaed seborrhoeic
keratoses
Case submitted as Atypical Vascular Proliferation after
Radiotherapy
Case 88
Female
aged 50 years.
Scarring alopecia
?DLE ?LP.
No DIF done - no tissue sent for DIF
Most popular diagnosis:
(+/- discoid) Lupus erythematosus
9.23
1
Case 89
Male
aged 64.
Papular eruption elbow.
Pruritus scalp and upper body.
Immunofluorescence:Granular IgA in
papillary dermis. No significant
fluorescence for IgG, IgM, C3 or fibrinogen
Diagnostic categories:
Dermatitis herpetiformis
Popularity:
10.00
Score:
1
Case 90
Male
aged 32.
Gets rash on fingers when hands wet
(periodically works at sea). Comes and
clears over 2 weeks - sore not itchy.
Clinically erythema multiforme or
chilblains.
Most popular diagnosis:
Classic perniosis / Chilblains
9.46
Case 91
Male
aged 17.
Lesion on right little finger.
Had from birth - catches.
Most popular diagnosis:
Supernumerary digit
8.59
Case 92
Female
aged 62.
Pigmented lesion left forearm, ?lentigo
maligna.
Macro:
Ellipse of skin, 24x15x13mm with a
pigmented macule, 11mm diameter. It has
an irregular margin and uniform
pigmentation.
Most popular diagnosis:
Lentigo maligna melanoma
6.75
Case 93
Female
aged 83.
Ulcerated lesion on scalp ?SCC ?BCC
Most popular diagnosis:
Metastatic adenocarcinoma
5.56
Case 94
Female
aged 30.
Localised infiltrative plaque anterior
abdomen.
Most popular diagnosis:
Morphoea
9.30
Case 95
Male aged 34.
4cm firm subcutaneous plaque left buttock.
Multiple other papules on trunk and limbs.
?subcutaneous sarcoidosis.
Immunohistology: cells are Positive - CD4, CD11c, CD15, CD33, CD43,
CD45, CD68, HLA-DR
Negative- CD2, CD3, CD5, CD7, CD8, CD10,
CD20, CD23, CD34, CD56, CD123, CD128,
TdT, MPO, MNF
Case submitted as :
Acute myeloid leukaemia of myelomonocytic lineage
Case 96
Female
aged 3.
Subungal lesion, little toe right foot.
Case submitted as :
Tungiasis
Case 97
Male
aged 32.
One year history of swelling behind the
nail plate of the right thumb.
Immunohistochemistry:
Vimentin and CD34 - positive,
S100, Desmin and Actin - Negative.
Case submitted as:
Superficial acral fibromyxoma
Case 98
Female
aged 50.
Groups of papules and nodules,
purple/red. Previously normal skin.
Initial differential diagnosis sarcoid versus
nodular prurigo versus lymphoma cutis.
Biopsied (first biopsy not submitted).
Three month follow up, nodules resolve
and scar with newer groups appearing, rebiopsied. No systemic disease.
Immunohistochemistry:
tumour cells CD2, CD4 positive, CD30 diffuse
and strong positivity.
CD3, CD5, CD8, CD20, CD45RA, ALK-1, EMA,
CD56, TIA-1, Granzyme all negative.
MUM1 positive in most tumour cells.
MIB1 staining shows high proliferation fraction.
Case submitted as :
CD30+ lymphoproliferative disorder and came with a
history strongly suggesting LyP
Case 99
Male
aged 27.
Very itchy blisters on shins and dystrophic
nails ?Epidermolysis bullosa
Case submitted as :
Dystrophic epidermolysis bullosa pruriginosa.
The
End