Transcript Document

Chapter 7: Pediatric ESRD 2014 A NNUAL V OLUME 2: E ND -S D ATA TAGE R R EPORT ENAL D ISEASE

vol 2 Figure 7.1. Incident & December 31 point prevalent ESRD patients (aged 0-19 years) (a) Incidence of ESRD in children

Data Source: Reference tables D3-D5, D7-D9, and special analyses, USRDS ESRD Database. Peritoneal dialysis consists of continuous ambulatory peritoneal dialysis and continuous cycling peritoneal dialysis. Abbreviations: ESRD, end-stage renal disease; HD, hemodialysis; PD, peritoneal dialysis; Tx, transplant.

Vol 2, ESRD, Ch 7

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vol 2 Figure 7.1. Incident & December 31 point prevalent ESRD patients (aged 0-19 years) (b) Prevalence of ESRD in children

Data Source: Reference tables D3-D5, D7-D9, and special analyses, USRDS ESRD Database. Peritoneal dialysis consists of continuous ambulatory peritoneal dialysis and continuous cycling peritoneal dialysis. Abbreviations: ESRD, end-stage renal disease; HD, hemodialysis; PD, peritoneal dialysis; Tx, transplant.

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vol 2 Table 7.1 : Distribution of reported incident pediatric ESRD patients by primary diagnosis, 2003-2007 (period A) and 2008-2012 (period B) (aged 0-19 years) All ESRD (reference) Diabetes

Type 2 Type 1

Glomerulonephritis (GN)

GN (histologically not examined) Focal glomerular sclerosis Membranous nephropathy MPGN GN type 1, diffuse MPGN Dense deposit disease, MPGN type 2 IgA nephropathy IgM nephropathy Rapidly progressive GN Post infectious GN, SBE Other proliferative GN

Secondary GN/vasculitis

Lupus nephritis Henoch-Schonlein syndrome Scleroderma Hemolytic uremic syndrome Polyarteritis Wegeners granulomatosis Other vasculitis and its derivatives Goodpasture syndrome Secondary GN, other

Total Patients

A 6,544 58 30 28 B 6,204 57 34 23

Incident %

A 100.0

0.9

0.5

0.4

B 100.0

1.0

0.6

0.4

1,541 275 824 1,336 194 721 14 80 708 405 23 * 31 77 26 130 * 77 34 75 20 134 14 56 21 67 656 332 28 * 24.7

4.4

13.2

0.5

1.2

0.4

2.1

0.1

1.2

0.2

1.3

11.4

6.5

0.4

0.1

0.4

1.2

11.3

5.7

0.5

0.1

23.0

3.3

12.4

0.6

1.3

0.3

2.3

0.2

1.0

119 11 60 58 14 14 113 21 56 54 33 16 1.9

0.2

1.0

0.9

0.2

0.2

1.9

0.4

1.0

0.9

0.6

0.3

6 14 15 15 16 14 14 15 16 17 15 18 16 17 15 15 15 12 17 16 14

Age Median

A 14 18 15 19 B 14 16 4 19 16 18 15 17 16 15 17 18 14 16 16 16 18 14 18 8 13 16 13 17 17 47.1

18.2

56.7

25.9

28.6

42.9

54.9

57.8

56.8

48.4

48.1

38.5

58.5

57.1

45.5

64.3

41.3

31.8

22.7

65.2

25.0

Male %

A 57.0

46.6

53.3

39.3

B 56.5

52.6

52.9

52.2

52.4

43.3

29.3

21.7

53.6

66.7

52.8

56.7

54.4

58.8

48.0

60.0

54.5

64.3

23.2

37.2

19.0

42.9

33.3

27.3

37.5

77.3

72.7

70.0

69.0

85.7

78.6

57.1

66.3

54.0

38.3

87.0

50.0

58.5

61.1

51.8

58.1

76.6

96.2

68.5

42.9

66.2

White %

A 64.3

55.2

56.7

53.6

B 65.7

57.9

61.8

52.2

African Am %

A B 24.7

37.9

30.0

46.4

23.0

36.8

32.4

43.5

64.1

69.6

59.2

47.1

66.7

75.0

76.1

71.4

75.0

71.4

65.7

57.8

32.8

85.7

66.7

33.2

26.5

42.0

32.3

14.3

3.8

19.2

42.9

22.1

28.6

26.3

36.7

50.4

4.3

50.0

23.8

26.9

35.2

59.0

7.1

33.3

29.0

20.6

36.1

44.1

24.0

10.0

13.4

21.4

16.1

82.3

85.7

89.3

72.2

93.9

81.3

17.6

9.1

23.3

25.9

7.1

7.1

12.4

4.8

7.1

16.7

3.0

18.8

Other Race %

A B 11.0

6.9

13.3

0.0

11.3

5.3

5.9

4.3

14.3

7.5

9.3

11.4

8.7

0.0

8.4

12.4

6.2

9.7

9.1

0.0

12.3

14.3

11.7

6.9

9.8

4.7

8.8

9.3

15.0

10.4

7.1

8.9

4.8

7.5

7.0

8.1

7.1

0.0

5.0

18.2

6.7

5.2

7.1

14.3

5.3

9.5

3.6

11.1

3.0

0.0

27.7

9.1

20.0

24.1

21.4

21.4

21.4

31.3

14.7

6.9

43.5

0.0

35.4

29.5

37.6

35.5

40.3

30.8

40.8

42.9

27.3

Transplant first year %

A B 41.4

8.6

13.3

3.6

43.6

15.8

8.8

26.1

36.5

25.3

39.4

41.2

42.7

20.0

44.0

14.3

21.4

14.3

43.3

18.1

7.2

39.3

33.3

35.4

19.0

23.2

29.6

18.2

25.0

3.4

0.0

3.3

1.7

0.0

0.0

0.0

2.5

4.5

5.9

0.0

25.0

2.2

3.6

1.9

0.0

2.6

3.8

0.8

0.0

2.6

Died first year %

A 3.7

12.1

10.0

14.3

B 3.3

12.3

17.6

4.3

1.7

1.5

1.9

0.0

4.0

0.0

0.0

0.0

1.8

4.8

1.5

4.3

4.5

3.6

33.3

4.4

0.0

1.8

5.6

3.0

6.3

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vol 2 Table 7.1 : Distribution of reported incident pediatric ESRD patients by primary diagnosis, 2003-2007 (period A) and 2008-2012 (period B) (aged 0-19 years) (cont’d) Interstitial nephritis/pyelonephritis

Nephropathy caused by other agents Nephrolithiasis Acquired obstructive uropathy Chronic pyelonephritis, reflux nephropathy Chronic interstitial nephritis Acute interstitial nephritis Disorders of calcium metabolism

Hypertensive/large vessel disease

Unspecified with renal failure Renal artery stenosis Renal artery occlusion

Cystic/hereditary/congenital diseases

Polycystic kidneys, adult type (dominant) Polycystic, infantile (recessive) Medullary cystic disease, inc. nephronophthisis Tuberous sclerosis Hereditary nephritis, Alport's syndrome Cystinosis Primary oxalosis Congenital nephrotic syndrome Drash syndrome, mesangial sclerosis Congenital ureterpelvic junction obstruction Congenital uretrovesical junction obstruction Other congenital obstructive uropathy Renal hypoplasia, dysplasia, oligonephronia Prune belly syndrome Other (congenital malformation syndromes)

Total Patients

A 17 136 15 31 25 514 698 82 79 266 * * 2,088 30 142 97 * 152 62 391 41 * 48 201 75 * * 283 B * 131 29 43 50 514 691 80 204 244 * * 2,229 33 150 106 * 133 49 289 37 11 30 143 60 * . 260

Incident %

A 0.3

2.2

0.2

0.5

0.4

8.2

11.2

1.3

1.3

4.3

0.1

0.1

33.5

0.5

2.3

1.6

0.1

2.4

1.0

6.3

0.7

0.1

0.8

3.2

1.2

0.0

0.1

4.5

B 0.2

2.3

0.5

0.7

0.9

8.8

11.9

1.4

3.5

4.2

0.2

0.1

38.3

0.6

2.6

1.8

0.1

2.3

0.8

5.0

0.6

0.2

0.5

2.5

1.0

0.1

4.5

.

Age Median

A 8 2 1 11 13 11 10 7 14 18 14 0 10 14 9 11 17 16 12 15 15 12 15 15 14 11 15 17 B 2 3 0 13 11 10 9 5 12 18 14 17 10 15 1 13 18 17 13 15 14 16 14 15 16 11 18 .

Male %

A 52.9

55.9

60.0

80.6

88.0

84.6

62.3

97.6

50.6

56.8

57.1

22.2

68.1

43.3

56.3

36.1

37.5

83.6

51.6

52.7

56.1

44.4

77.1

44.3

57.3

33.3

20.0

55.8

B 80.0

54.2

58.6

86.0

86.0

81.5

62.4

98.8

56.4

57.4

66.7

20.0

67.4

57.6

44.7

50.0

40.0

83.5

59.2

50.9

56.8

27.3

76.7

45.5

46.7

100.0

57.3

.

White %

A 82.4

71.3

80.0

77.4

72.0

68.5

76.9

75.6

83.5

50.0

85.7

88.9

75.2

83.3

76.1

84.5

50.0

74.3

90.3

81.3

82.9

100.0

66.7

88.6

73.3

33.3

80.0

52.3

B 80.0

80.2

82.8

60.5

70.0

71.8

75.5

67.5

78.9

52.9

77.8

80.0

74.8

72.7

78.0

84.9

40.0

64.7

91.8

81.3

83.8

90.9

80.0

84.6

73.3

50.0

54.6

.

10.0

12.2

17.2

39.5

20.0

23.7

16.9

27.5

10.3

43.4

11.1

20.0

18.5

27.3

16.7

7.5

60.0

24.1

8.2

11.1

10.8

0.0

16.7

7.0

16.7

50.0

41.5

.

African Am %

A B 11.8

19.9

0.0

16.1

28.0

23.5

15.9

22.0

13.9

43.6

14.3

0.0

18.0

13.3

16.9

4.1

50.0

20.4

9.7

12.8

14.6

0.0

22.9

6.5

20.0

66.7

20.0

41.3

10.0

7.6

0.0

0.0

10.0

4.5

7.5

5.0

10.8

3.7

11.1

0.0

6.6

0.0

5.3

7.5

0.0

11.3

0.0

7.6

5.4

9.1

3.3

8.4

10.0

0.0

3.8

.

Other Race %

A B 5.9

8.8

20.0

6.5

0.0

8.0

7.2

2.4

2.5

6.4

0.0

11.1

6.8

3.3

7.0

11.3

0.0

5.3

0.0

5.9

2.4

0.0

10.4

5.0

6.7

0.0

0.0

6.4

70.0

48.9

34.5

48.8

50.0

48.2

52.2

55.0

51.0

18.0

55.6

20.0

51.1

51.5

39.3

70.8

20.0

48.9

75.5

54.7

29.7

81.8

46.7

60.8

56.7

50.0

19.6

.

Transplant first year

A

%

B 47.1

50.7

26.7

51.6

52.0

45.1

50.0

56.1

55.7

22.9

42.9

22.2

51.1

60.0

53.5

69.1

25.0

50.0

77.4

47.8

53.7

100.0

45.8

48.3

46.7

0.0

20.0

23.7

Died first year %

A 0.0

8.1

13.3

0.0

0.0

2.7

3.4

0.0

2.5

5.3

0.0

11.1

3.2

0.0

7.0

1.0

0.0

1.3

0.0

2.0

9.8

0.0

0.0

0.5

2.7

0.0

0.0

5.3

B 0.0

4.6

6.9

2.3

2.0

1.2

2.9

1.3

4.4

4.1

0.0

0.0

2.8

0.0

11.3

0.0

0.0

0.0

0.0

4.8

10.8

9.1

0.0

2.8

3.3

50.0

3.8

.

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vol 2 Table 7.1 : Distribution of reported incident pediatric ESRD patients by primary diagnosis, 2003-2007 (period A) and 2008-2012 (period B) (aged 0-19 years) (cont’d) Total Patients

A B

Incident %

A B

Age Median

A B

Male %

A B

White %

A B

African Am %

A B

Other Race %

A B

Transplant first year %

A B

Died first year %

A B

Neoplasms/tumors

Renal tumor (malignant) Renal tumor (unspecified) Transplanted organ complication, unspecified Transplanted kidney complication Transplanted liver complication Transplanted heart complication Bone marrow transplant complication

Miscellaneous conditions

Sickle cell disease/anemia Post partum renal failure AIDS nephropathy Traumatic or surgical loss of kidney(s) Hepatorenal syndrome Tubular necrosis Other renal disorders

Etiology uncertain Missing

* 44 15 * 114 205 600 308 161 38 * 21 46 * 20 12 406 14 0.1

0.7

0.2

0.1

1.8

3.3

9.6

4.9

0.3

0.2

6.5

0.2

2.6

0.6

0.1

0.3

0.7

0.1

* 15 * * 131 210 476 390 122 33 * * 13 * 25 25 389 * 17 16 8 11 2 13 15 13 14 12 13 18 14 5 17 14 15 17 0.1

0.3

0.2

0.1

2.3

3.6

8.2

6.7

0.4

0.4

6.7

0.2

2.1

0.6

0.0

0.0

0.2

0.1

11.1

47.7

66.7

25.0

51.8

60.5

58.5

62.0

50.9

44.7

0.0

47.6

58.7

62.5

55.0

50.0

55.4

64.3

19 18 13 16 11 12 15 14 15 17 13 18 14 5 1 16 17 15 66.7

13.6

93.3

75.0

78.9

74.1

71.8

13.0

71.4

63.2

50.0

71.4

73.9

62.5

80.0

91.7

66.7

0.0

0.0

53.3

60.0

50.0

60.3

52.4

57.1

59.2

50.8

39.4

100.0

50.0

76.9

25.0

52.0

60.0

55.3

90.0

33.3

86.4

6.7

25.0

14.0

19.5

20.3

3.9

21.1

28.9

25.0

23.8

19.6

25.0

15.0

8.3

28.1

100.0

71.4

0.0

50.0

66.7

79.4

80.0

70.2

14.9

68.0

66.7

0.0

50.0

84.6

62.5

64.0

64.0

73.8

10.0

0.0

0.0

0.0

0.0

7.0

6.3

7.8

83.1

7.5

7.9

25.0

4.8

6.5

12.5

5.0

0.0

5.2

0.0

14.3

100.0

40.0

0.0

14.5

11.0

21.8

7.7

22.1

27.3

100.0

50.0

15.4

12.5

24.0

28.0

18.3

90.0

33.3

0.0

40.0

0.0

15.8

57.6

39.3

96.4

32.3

7.9

50.0

28.6

58.7

50.0

30.0

8.3

36.2

14.3

14.3

0.0

10.0

33.3

6.1

9.0

8.0

77.4

9.8

6.1

0.0

0.0

0.0

25.0

12.0

8.0

8.0

0.0

0.0

0.0

20.0

50.0

20.6

51.4

44.1

90.5

32.0

18.2

100.0

50.0

23.1

87.5

48.0

12.0

36.2

10.0

0.0

20.0

10.0

16.7

10.7

3.8

1.5

2.3

15.6

15.2

0.0

0.0

0.0

0.0

16.0

12.0

6.9

0.0

0.0

13.6

13.3

75.0

9.6

5.4

3.2

1.3

14.3

26.3

0.0

19.0

0.0

0.0

20.0

33.3

8.9

21.4

Data Source: Special analyses, USRDS ESRD Database. Abbreviations: AIDS, acquired-immune deficiency syndrome; ESRD, end-stage renal disease; GN glomerulonephritis; IgA immunoglobulin A; IgM, immunoglobulin M; MPGN, membranoproliferative glomerulonephritis; SBE, sub-acute bacterial endocarditis.

*Suppressed due to inadequate sample size.

.Zero values in this cell.

Vol 2, ESRD, Ch 7

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vol 2 Figure 7.2 Trends in pediatric transplantation (aged 0-19 years) (a) Incidence rate of ESRD and transplant rate in children

Data Source: Reference tables A1, E9, M1, and special analyses, USRDS ESRD Database. The rate of ESRD per million among the U.S.

population age 0-19 and the rate of transplantation in dialysis patients age 0-19 at the time of transplant, 1989–2012. Abbreviations: ESRD, end-stage renal disease.

Vol 2, ESRD, Ch 7

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vol 2 Figure 7.2 Trends in pediatric transplantation (aged 0-19 years) (b) Waiting list count

Data Source: Reference tables E2, E3, and special analyses, USRDS ESRD Database. The waiting list count provides the number of pediatric candidates aged 0-19 years on the Organ Procurement and Transplantation Network kidney transplant waiting list on December 31 of each year for first and subsequent kidney alone or kidney plus pancreas transplantation. Candidates listed at more than one center on December 31 are counted only once. There are no data available for median waiting list time for patients with prior transplants listed after 2008. Abbreviations: Tx, transplant.

Vol 2, ESRD, Ch 7

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vol 2 Figure 7.2 Trends in pediatric transplantation (aged 0-19 years) (c) Total transplants

Data Source: Reference tables E8, E8(2), E8(3), and special analyses, USRDS ESRD Database. This figure represents kidney alone and kidney plus pancreas transplant counts for all pediatric candidates.

Vol 2, ESRD, Ch 7

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vol 2 Figure 7.2 Trends in pediatric transplantation (aged 0-19 years) (d) Total functioning transplants

Data Source: Reference table D9. This is the cumulative count of functioning pediatric kidney and kidney-pancreas transplants.

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vol 2 Figure 7.3 Live and deceased donor transplants in pediatric patients (aged 0-19 years) (a) Transplant rate in pediatric dialysis patients by age

Data Source: Reference Table E9, and special analyses, USRDS ESRD Database. Includes transplant year between 1991–2012.

Vol 2, ESRD, Ch 7

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vol 2 Figure 7.3 Live and deceased donor transplants in pediatric patients (aged 0-19 years) (b) Transplant rate in pediatric dialysis patients by sex

Data Source: Reference Table E9, and special analyses, USRDS ESRD Database. Includes transplant year between 1991–2012.

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vol 2 Figure 7.3 Live and deceased donor transplants in pediatric patients (aged 0-19 years) (c) Transplant rate in pediatric dialysis patients by race

Data Source: Reference Table E9, and special analyses, USRDS ESRD Database. Includes transplant year between 1991–2012.

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vol 2 Figure 7.4 Hospitalization rates in pediatric patients (aged 0-19 years) (a) One-year adjusted all-cause hospitalization rates in pediatric patients by age

Data Source: Special analyses, USRDS ESRD Database. Includes incident ESRD patients in the years 2002-2011, surviving the first 90 days after ESRD initiation and followed from day 90. Adjusted for sex, race, primary diagnosis and Hispanic ethnicity. Ref: incident ESRD patients age 0-19, 2010-2011. Abbreviations: HD, hemodialysis; PD, peritoneal dialysis; Tx, transplant.

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vol 2 Figure 7.4 Hospitalization rates in pediatric patients (aged 0-19 years) (b) One-year adjusted all-cause hospitalization rates in pediatric patients by modality

Data Source: Special analyses, USRDS ESRD Database. Includes incident ESRD patients in the years 2002-2011, surviving the first 90 days after ESRD initiation and followed from day 90. Adjusted for sex, race, primary diagnosis and Hispanic ethnicity. Ref: incident ESRD patients age 0-19, 2010-2011. Abbreviations: HD, hemodialysis; PD, peritoneal dialysis; Tx, transplant.

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vol 2 Figure 7.5 Cardiovascular hospitalization rates in children (aged 0-19 years) (a) One-year adjusted cardiovascular hospitalization rates in pediatric patients by age

Data Source: Special analyses, USRDS ESRD Database. Includes incident ESRD patients in the years 2002-2011, surviving the first 90 days after ESRD initiation and followed from day 90. Adjusted for sex, race, primary diagnosis and Hispanic ethnicity. Ref: incident ESRD patients age 0-19, 2010-2011. Abbreviations: HD, hemodialysis; PD, peritoneal dialysis; Tx, transplant.

Vol 2, ESRD, Ch 7

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vol 2 Figure 7.5 Cardiovascular hospitalization rates in children (aged 0-19 years) (b) One-year adjusted cardiovascular hospitalization rates in pediatric patients by modality

Data Source: Special analyses, USRDS ESRD Database. Includes incident ESRD patients in the years 2002-2011, surviving the first 90 days after ESRD initiation and followed from day 90. Adjusted for sex, race, primary diagnosis and Hispanic ethnicity. Ref: incident ESRD patients age 0-19, 2010-2011. Abbreviations: HD, hemodialysis; PD, peritoneal dialysis; Tx, transplant.

Vol 2, ESRD, Ch 7

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vol 2 Figure 7.6 Infection hospitalization rates in children (aged 0-19 years) (a) One-year adjusted hospitalization rates for infection in pediatric patients by age

Data Source: Special analyses, USRDS ESRD Database. Includes incident ESRD patients in the years 2002-2011, surviving the first 90 days after ESRD initiation and followed from day 90. Adjusted for sex, race, primary diagnosis and Hispanic ethnicity. Ref: incident ESRD patients age 0-19, 2010-2011. Abbreviations: HD, hemodialysis; PD, peritoneal dialysis; Tx, transplant.

Vol 2, ESRD, Ch 7

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vol 2 Figure 7.6 Infection hospitalization rates in children (aged 0-19 years) (b) One-year adjusted hospitalization rates for infection in pediatric patients by modality

Data Source: Special analyses, USRDS ESRD Database. Includes incident ESRD patients in the years 2002-2011, surviving the first 90 days after ESRD initiation and followed from day 90. Adjusted for sex, race, primary diagnosis and Hispanic ethnicity. Ref: incident ESRD patients age 0-19, 2010-2011. Abbreviations: HD, hemodialysis; PD, peritoneal dialysis; Tx, transplant.

Vol 2, ESRD, Ch 7

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vol 2 Figure 7.7 One year transplant outcomes by donor type (aged 0-19 years) (a) Outcomes: deceased donor transplants in pediatric patients, adjusted

Data Source: Reference tables F2, F14, I26. Probabilities for all-cause graft failure and return to dialysis or retransplant are adjusted for age, sex, race, primary diagnosis, and first versus subsequent transplant. All-cause graft failure includes retransplant, return to dialysis, and death. The death outcome is not censored at graft failure, and includes deaths that occur after retransplant or return to dialysis. Probabilities of death are adjusted for age, sex, race, and primary diagnosis. The reference population for all-cause graft failure and return to dialysis or repeat transplantation is all pediatric patients receiving a kidney alone transplant in 2011. The reference population for death is incident pediatric ESRD patients in 2011.

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vol 2 Figure 7.7 One year transplant outcomes by donor type (aged 0-19 years) (b) Outcomes: live donor transplants in pediatric patients, adjusted

Data Source: Reference tables F8, F20, I32. Probabilities for all-cause graft failure and return to dialysis or retransplant are adjusted for age, sex, race, primary diagnosis, and first versus subsequent transplant. All-cause graft failure includes retransplant, return to dialysis, and death. The death outcome is not censored at graft failure, and includes deaths that occur after retransplant or return to dialysis. Probabilities of death are adjusted for age, sex, race, and primary diagnosis. The reference population for all-cause graft failure and return to dialysis or repeat transplantation is all pediatric patients receiving a kidney alone transplant in 2011. The reference population for death is incident pediatric ESRD patients in 2011.

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vol 2 Figure 7.8 Mortality rates in children with ESRD (aged 0-19 years) (a) One-year adjusted all-cause mortality rates in pediatric patients by age

Data Source: Special analyses, USRDS ESRD Database. Incident dialysis and transplant patients defined at the onset of dialysis or the day of transplant without the 60-day rule; followed to December 31, 2012. Adjusted for age, sex, race, Hispanic ethnicity, and primary diagnosis. Ref: incident ESRD patients age 0-19, 2010-2011. Abbreviations: HD, hemodialysis; PD, peritoneal dialysis; Tx, transplant.

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vol 2 Figure 7.8 Mortality rates in children with ESRD (aged 0-19 years) (b) One-year adjusted all-cause mortality rates in pediatric patients by modality

Data Source: Special analyses, USRDS ESRD Database. Incident dialysis and transplant patients defined at the onset of dialysis or the day of transplant without the 60-day rule; followed to December 31, 2012. Adjusted for age, sex, race, Hispanic ethnicity, and primary diagnosis. Ref: incident ESRD patients age 0-19, 2010-2011. Abbreviations: HD, hemodialysis; PD, peritoneal dialysis; Tx, transplant.

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vol 2 Figure 7.9 Cardiovascular mortality in children with ESRD (aged 0-19 years) (a) One-year adjusted all-cause cardiovascular mortality rates in pediatric patients by age

Data Source: Special analyses, USRDS ESRD Database. Incident dialysis and transplant patients defined at the onset of dialysis or the day of transplant without the 60-day rule; followed to December 31, 2012. Adjusted for age, sex, race, Hispanic ethnicity, and primary diagnosis. Ref: incident ESRD patients age 0-19, 2010-2011. Abbreviations: HD, hemodialysis; PD, peritoneal dialysis; Tx, transplant.

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vol 2 Figure 7.9 Cardiovascular mortality in children with ESRD (aged 0-19 years) (b) One-year adjusted all-cause cardiovascular mortality rates in pediatric patients by modality

Data Source: Special analyses, USRDS ESRD Database. Incident dialysis and transplant patients defined at the onset of dialysis or the day of transplant without the 60-day rule; followed to December 31, 2012. Adjusted for age, sex, race, Hispanic ethnicity, and primary diagnosis. Ref: incident ESRD patients age 0-19, 2010-2011. Abbreviations: HD, hemodialysis; PD, peritoneal dialysis; Tx, transplant.

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vol 2 Figure 7.10 Infection-related mortality in children with ESRD (aged 0-19 years) (a) One-year adjusted rates of mortality due to infection in pediatric patients by age

Data Source: Special analyses, USRDS ESRD Database. Incident dialysis and transplant patients defined at the onset of dialysis or the day of transplant without the 60-day rule; followed to December 31, 2012. Adjusted for age, sex, race, Hispanic ethnicity, and primary diagnosis. Ref: incident ESRD patients age 0-19, 2010-2011. Abbreviations: HD, hemodialysis; PD, peritoneal dialysis; Tx, transplant.

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vol 2 Figure 7.10 Infection-related mortality in children with ESRD (aged 0-19 years) (b) One-year adjusted rates of mortality due to infection in pediatric patients by modality

Data Source: Special analyses, USRDS ESRD Database. Incident dialysis and transplant patients defined at the onset of dialysis or the day of transplant without the 60-day rule; followed to December 31, 2012. Adjusted for age, sex, race, Hispanic ethnicity, and primary diagnosis. Ref: incident ESRD patients age 0-19, 2010-2011. Abbreviations: HD, hemodialysis; PD, peritoneal dialysis; Tx, transplant.

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vol 2 Figure 7.11 Pediatric ESRD patient survival by age and modality (aged 0-19 years) (a) Adjusted 5 year survival in pediatric patients from day 1 by age, years 2003-2007

Data Source: Special analyses, USRDS ESRD Database. Incident dialysis and transplant patients defined at the onset of dialysis or the day of transplant without the 60-day rule; followed to December 31, 2012. Adjusted for age, sex, race, Hispanic ethnicity, and primary diagnosis. Ref: incident ESRD patients age 0-19, 2010-2011. Abbreviations: HD, hemodialysis; PD, peritoneal dialysis; Tx, transplant.

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vol 2 Figure 7.11 Pediatric ESRD patient survival by age and modality (aged 0-19 years) (b) Adjusted 5 year survival in pediatric patients from day 1 by modality, years 2003-2007

Data Source: Special analyses, USRDS ESRD Database. Incident dialysis and transplant patients defined at the onset of dialysis or the day of transplant without the 60-day rule; followed to December 31, 2012. Adjusted for age, sex, race, Hispanic ethnicity, and primary diagnosis. Ref: incident ESRD patients age 0-19, 2010-2011. Abbreviations: HD, hemodialysis; PD, peritoneal dialysis; Tx, transplant.

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