Transcript Central Tendency” - North Dakota State University
Human Neuropsychology (486 / 686) Lecture Chapter 26 .
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Neurological Disorders
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The Neurological Examination
Patient History Patient and family background and disease history Observation of behavior and state of awareness Simple tests of memory and speech The Physical Examination Head and body size, Blood pressure Various reflexes Smell and taste, sensation and hearing Sensitivity to light Muscular strength Object recognition, speech repetition
Vascular Disorders
Cerebral vascular accident (CVA) aka Stroke: sudden appearance of neurological symptoms resulting from disruption of blood flow to the brain Mild to severe
Vascular Disorders
Ischemia – lack of blood supply Causes: Thrombosis, Embolism, Cerebral Arteriosclerosis, Cerebral Vascular Insufficiency (transient ischemia) Migraine stroke - Appears as a transient ischemic attack Symptoms: Impaired sensory function, Numbness, Difficulty moving, Aphasia Cerebral Hemorrhage – bleeding most common cause high blood pressure
Vascular Disorders
Angiomas Collection of abnormal blood vessels Angiomas -
Arteriovenous Malformation
Aneurysms Vascular dilation
Drug therapies Anticoagulants, blood pressure meds,steroids
Treatments
Surgeries
Traumatic Brain Injuries
Open Head Injury – penetrating wounds, deficits specific to injury site, greatest risk of infection Closed Head Injury – forces that cause damage: coup, countercoup, twisting and shearing, bleeding and edema
Closed-Head Injuries
Coma
Behavioral effects
General complaints
Risk for future head injury
Cumulative effects
Behavioral Assessment
Glasgow Coma Scale
Behavioral Assessment
Post-Traumatic Amnesia (PTA)
Epilepsy
Three common symptoms Diagnosed with EEG
Types of Seizures:
Focal
Jacksonian, Complex partial
Generalized
Grand Mal, Petit Mal
Akinetic and Myoclonic
Treatment for Epilepsy:
Anticonvulsant drugs Surgery
Tumors
Benign vs Malignant Encapsulated vs Infiltrating Types: Gliomas, Meningiomas, Metastatic Treatment: Surgery, Radiation, Chemotherapy
Gliomas:
astrocytoma oligodendroglioma ependymoma
Menigiomas
Metastatic tumors
From Lung cancer From skin cancer
Headaches: Migraine
Classic migraine Common migraine Cluster headache Hemiplegic and ophthalmologic migraine Treatment: Specific drugs to prevent and control pain e.g. topamax, ergotamine
Other Headaches
Neurological disease related Causes: tumor, head trauma,infections, vascular malformation, hypertension treatment: treat the cause Muscle-contraction headaches ( tension) treatment: Analgesics, Muscle relaxants, tranquilizers, posture improvement, reduce stress Nonmigrainous vascular headaches Causes: Fever, anoxia, anemia, high altitude, physical effort, hypoglycemia, food, or chemical agents
Infections
Interfere with blood supply, Disrupt glucose or oxygen metabolism, Alter cell membranes, Form pus, Edema Types: Viruses – neurotropic, pantropic treatment: Difficult to treat; no antidote Bacteria – Meningitis, Brain abscesses treatment: Antibiotics, Drainage Mycotic Infections – fungus Parasitic Infections – Amebiasis,Malaria No satisfactory treatment, Antibiotics
Motor Neurons and the Spinal Cord
Myasthenia Gravis Poliomyelitis Multiple Sclerosis Paraplegia Brown-S équard Syndrome Hemiplegia
1. Moran and Desimone showed that monkey neurons responded selectively to specific stimuli in their visual fields: a. after reward training b. when the stimulus was presented to the right visual hemifield c. when the stimulus was presented to the left visual hemifield d. when the stimulus was a particular color
2. Which of the following processes are necessary prerequisites of consciousness?
a. attention and perception b. working memory c. arousal d. all of these processes are necessary
3. Dendrite growth differs from axonal growth in that: a. axons grow faster than dendrites in order to play a role in shaping dendritic growth b. axons grow faster than dendrites in order to reach a larger maximum size c. dendrite grow faster than axons in order to play a role in shaping axonal growth d. dendrite grow faster than axons in order to reach a larger maximum size
4. After a series of higher than normal stimulations followed by a rest period, a baseline stimulation to a neuron elicits a greater excitatory post synaptic potential from another neuron that receives it’s projections. This phenomenon is known as: a. kindling b. long-term potentiation c. ischemia d. synaptogenesis
5. Countercoup damage is the result of: a. aneurysm b. infection c. closed head injury d. open head injury
6. What are Piaget’s four stages of cognitive development? Briefly characterize each stage. 7. What evidence is there that motor maps can be modified by experience? 8. What is the difference between an angioma and an aneurysm?