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GENERAL APPROACH TO THE PREGNANT WOMAN Pregnancy Pregnancy (gestation) is the maternal condition of having a developing fetus in the body. The human conceptus from fertilization through the eighth week of pregnancy is termed an embryo; from the eighth week until delivery, it is a fetus. Terminology Antepartum - before delivery Postpartum - after delivery Prenatal - occurring before the birth Gravida - number of pregnancies Para - number of pregnancies carried to full term Primigravida - woman who is pregnant for the first time Primipara - woman who has given birth to her first child Multiparous - woman who has given birth multiple times Gestation - period of time for intrauterine fetal development The diseases specific to pregnancy Hyperemesis gravidarum Gestational diabetes Preeclampsia (PIH) Postpartum depression Common diseases that significantly affect pregnancy include ; CVS diseases Diabetes mellitus Essential hypertension Endocrine disorders Autoimmune diseases Most pregnant women will have at least one of the following symptoms : Backache Breathlessness Fatique Palpitations Ankle swelling Indigestion Nausea and vomiting Constipation Urinary frequency Early signs of pregnancy A woman may perceive early signs of pregnancy within a few days of the first missed menstrual period. Usually the earliest signs are Mastodynia (breast tenderness), fatique, and some abnormal reaction to food. ASSESSMENT TURKISH MINISTRY OF HEALTH RECOMMENDS 1. VISIT : 0-14 WEEK 2. VISIT : 18-24 WEEK 3. VISIT : 30-32 WEEK 4. VISIT : 36-38 WEEK The first prenatal visit The first prenatal visit ideally should occur between 6 and 8 weeks of gestation. The purpose of the first visit is to identify all risk factors involving the mother and fetus. Once identified, high-risk pregnancies require individualized specialized care. Certain specific prenatal care tasks for the physician include the following Establish the diagnosis and estimated due date. Diagnose and treat prenatal disease Promote a healthy pregnancy Establish the diagnosis and estimated due date The date of the last menstrual period should be determined. If not known exactly, the date should be estimated. Information about the normal menstrual cycle should be obtained. Nägele’s rule : EDD = “ estimated due date “ or “ estimated date of confinement “ EDD = LMP ( Date of the first day of the last menstrual period ) + 1 year and seven days – three months The length of human gestation is 280 days, or 40 weeks, as counted from the first day of the LMP to the EDD. “ A term pregnancy “ may extend from 37 t0 42 weeks gestation. If the patient is unsure of her LMP, an ultrasound examination can date the pregnancy with a first trimester accuracy of plus or minus 4 days An examiner may have difficulty determining the presence of pregnancy in the first 6 to 8 weeks of gestation.. Although the uterus is usually palpably enlarged and soft ( Hegar’s sign ) within 6 weeks from the last menstrual period, the exact size often is not easy to determine. This is particularly true in obese women and in women who have had several children. Chadwick’s sign ( vaginal and cervical cyanosis ), -a purplish discoloration of the uterine cervix resulting from the increased blood supply-, is often present by 6 weeks from the LMP. There are many components of prenatal care. Initially, confirmation of the diagnosis of pregnancy and the estimated gestational age must be established. Next is a full history and physical examination with laboratory evaluation. The physician questions the patient regarding her, past obstetrical experiences, past medical illnesses, surgical procedures, exposures to infection, and risk of genetic diseases. past obstetrical experiences The following information is necessary: Length of gestation, Birth weight Fetal outcome Length of labor Fetal presentation Type of delivery ( vaginal, forceps or vacuum, cesarean section ), Complications “ A history of preterm labor is the most important risk factor for its development in subsequent pregnancies. “ past medical illnesses Some of the most important medical illnesses that cause problems in pregnancy include heart disease, particularly valvular diseases, worsen with the stress of pregnancy; and diabetes mellitus, since altered glucose levels may result in congenital malformations or in a difficult birth because of a large baby. Troublesome habits during pregnancy are use of cigarettes, which results in an increased incidence of intrauterine growth retardation, preterm labor, and abruptio placenta; alcohol use, which may result in the fetal alcohol syndrome, and illicit drug use, with its potential for numoreous congenital defects and HIV infection. Sexually transmitted diseases and other infectious diseases that put the fetus at risk for infection are : Herpes simplex type II, Syphilis, Gonorrhea, Chlamydia, HIV, Hepatitis B, Tuberculosis Toxoplasmosis A history of any genetic diseases among the patient, the father, or both extended families should be sought, particularly of the diseases that are diagnosable during pregnancy. The risk of Down syndrome increases with maternal age, and patients of “ advanced maternal age “ (>35 years) are advised of serum and amniotic fluid tests available for its prenatal diagnosis. The initial physical examination should include; measurement of blood pressure and weight, breast exam and, pelvic exam for uterine sizing and abnormalities. The external genitalia, vagina, and cervix should be inspected carefully for abnormalities that may lead to difficulties in pregnancy, labor, or delivery. complete physical examination The physician performs a complete physical examination early in the pregnancy, paying special attention to the thyroid, in which abnormalities can create fetal hyperthyroidism or hypothyroidism result in decreased intellectual function ; the breasts, in which abnormal masses may grow quickly under the influence of gestational hormones; and the heart, in which abnormal sounds may indicate a heart disease that causes difficulty during pregnancy. Laboratory data obtained routinely during pregnancy include ; 1. A complete blood count ( CBC ), to determine the presence of anemia and to obtain a baseline platelet count 2. Blood type and Rh, to identify Rhnegative patients 3. Urine culture, to identify patients with asymptomatic bacteriuria, with its attendant risks of pyelonephritis and preterm labor 4. Rubella screen, to determine the patient’s rubella status ( if no antibody is present, the patient is advised to avoid sick children during the pregnancy and to obtain the rubella immunization during the post partum period 5. Papanicolau smear, to identify patients with dysplasia, who need treatment during pregnancy 6. Gonorrhea cervical culture, and hepatitis B surface antigen, to identify patients whose infants are at risk for prenatal or perinatal transmission. A Papanicolau smear should be obtained for every patient at her first prenatal visit unless a negative exam has been obtained within the last 6 months. A hematocrit and a urine culture should be obtained for all patients as well. Anemia is defined as a hemoglobin of less than 11.0 gm / dL in the first and third trimester and less than 10.5 gm / dL in the second trimester, or, equivalently, a hematocrit of 33 and 32 per cent, respectively. The most common cause of anemia in pregnancy is iron deficiency. Midtrimester screening tests a. The couple should be counseled regarding maternal serum α-fetoprotein ( AFP ) testing for birth defects to be completed between the fifteenth and twentieth weeks of gestation ( best between the sixteenth and eightteenth ). Although there are numoreous causes for an abnormal AFP value, its primary purpose is to screen for neural tube defects. Abnormal results are further evaluated by ultrasonography and amniocentesis. b. At 24 to 28 weeks, a one-hour glucola ( blood glucose measurement one hour after a 50 mg oral glucose load ) is obtained to screen for gestational diabetes in all pregnant patients. Those with a particular risk ( e.g., previous gestational diabetes or fetal macrosomia ) may warrant earlier testing. Values greater than or equal 140 mg / dl are evaluated with a three-hour oral glucose tolerance test. Repeat hemoglobin and hematocrit are obtained at 26 to 30 weeks to determine the need for iron supplementation. d. Repeat serologic testing for syphilis is recommended at 36 weeks for high risk groups. e. At 28 to 30 weeks, an antibody screen is obtained in Rh-negative women. f. Repeat third-trimester screening for gonorrhea and chlamydia is recommended in high-risk population. c. Promote a healthy pregnancy The physician emphasizes to the patient her responsibilities in providing as healthy an environment for the fetus as possible and often asks the patient to read further on the subject. Good nutrition during pregnancy Women should be encouraged to eat a balanced, nutritious diet, including whole – grain cereals and breads , vegetables and fruit, protein-rich foods , and dairy products. A healthy diet is achievable from many cultural perspectives , and the starting point has to be with foods that are familiar and enjoyed by the patient. Vitamin and mineral supplementation is not indicated by women who eat well-balanced diets, except for iron and folic acid ( Folic acid, 400 micrograms daily should be begun at the first prenatal visit and continued through the first three months of pregnancy) It is not necessary to begin iron supplementation at the first prenatal visit. For most women it should be started in the second trimester and continued throughout pregnancy at a dose of 30 mg of elemental iron per day. Calcium supplementation is recommended only in women who cannot eat diary products. The recommended daily allowance of calcium for the pregnant woman is the same as that for the nonpregnant woman, 1200 mg / day. Subsequent visits The standart schedule for prenatal office visits: 0-32 weeks, once every 4 weeks; 32-36 weeks,once every 2 weeks; 36 weeks to delivery, once each week. Preparation for labor As term approaches, the patient should be instructed about the following danger signals: Rupture of membranes Vaginal bleeding Evidence of preeclampsia (marked swelling of hands and face, blurring of vision, headache, epigastric pain, convulsions) Chills or fever Severe abdominal or back pain What are Leopold maneuvers? These are performed at each third trimester visit to assess the presentation, position, engagement of the fetus by using 4 different maneuvers. Leopold maneuver #1 Palpate the fundus of the uterus to determine which fetal parts are in this portion of the uterus. It is used for outlining uterine contour and locating head Leopold maneuver #2 Palpate either side of the abdomen to find the fetal back. It is used for locating the spine Leopold maneuver #3 Palpate just above the pubic symphysis for the presenting part. It is used for determining the engagement Leopold maneuver #4 Palpate either side of the lower abdomen just above the pelvic inlet to determine if the head is flexed or extended It is used to determine the descent