Transcript Document

CALIXARENE BASED
CHEMOSENSORS
HANNOVER MESSE-2007
16-20 April, 2007
Hannover
Iurii MATVIEIEV
+38 044 551-1628
+38 050 501-1393
[email protected]
National Academy of Sciences of Ukraine
Institute of Organic Chemistry
Institute of Semiconductor Physics
Institute of Macromolecular Chemistry
Kiev
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Talk outline
1.
2.
3.
4.
5.
6.
7.
8.
What is needed in the market?
Brief technology description.
Stage of development.
Who needs it & how many will they need?
What is my unique technology advantage?
Competitive matrix.
How will I beat the competition?
Opportunity for joint work.
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Proprietary information statement
• The technology material presented in this talk is
available for licensing or joint product development.
• None of the slides contain any confidential or
proprietary information which would prevent patenting
the technology.
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Problem Description & Market Need
(What is the problem? Or, What is needed in the market?
And, How big is the potential market? What is the disease
(if it’s a medical talk)? )
• Variety of sensors provide increased efficiency and
ecological safety in many industries. Their use is important
factor for improvement of the life quality for modern
society.
• Application of traditional methods for monitoring of
hazardous substances in variable environment (air, water,
waste, etc.) is not often effective and has a range of
drawbacks, mainly complicity and long-term exposure.
• The main problem in developing of sensor systems is to
supply them with the exceptional selectivity towards a
different analytes to be detected in environment.
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Brief technology description
CALIXARENE BASED CHEMOSENSOR GAZ-1
Main technical characteristics
•
•
•
Array of quartz crystal resonators
covered with calixarenecontaining
receptors which have different
sensitivity towards different volatile
organic molecules were developed.
Due to adsorption of analyte
molecules onto sensitive surfaces of
sensors
frequency
of
quartz
resonators is reducing. This frequency
shift is considered as a sensor
response.
Obtained array of sensors responses
to pulse of analyte vapor is used for
“teaching” system and after that – for
recognition of chemical image of
analyte by means of special
mathematical apparatus for statistical
treatment (PCA, Neural Network,
etc.).
Working cell volume
9 sm3
Number of channel
8; Frequency drift less 0.5 Hz/ 1h
Counter range
0 –16 MHz;
Resolution
1 Hz;
Time single freq. count. 1s;
Time of measuring for recognition
less 5 min;
Number of recognizing chem. images
more 10;
Range of analyte concentration
10 – 10000
ppm;
Working temperature
20 – 30
Software
DOS, Win9X;
Power supply
12V/0.4A
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Advantages
(What is my unique and overwhelming technology advantage?)
• Calixarene based Electronic Nose is used
for: monitoring of hazardous pollutants in
environment; quality control in food
industry and agriculture; quality control of
perfumes and beverages.
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Experimental results
• Kinetic response strongly depends on interaction between
sensitive layer and analyte molecules. Thus, choosing array
for given purpose we consider physical-chemical features of
sensitive layers.
90
Coating type
Response (freuency shift, Hz)
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CA2
CA6
CA7
CA10
CA11
CA12
CA13
CA14
70
60
50
40
30
20
10
0
•
Toluene
Benzene
n-xylene
Chloroform
Dichlorethane
CH
2
Cl
2
CCl
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Analyte
Response of several sensors to various analytes
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Stage of development (clinical tests if medical) and
international patents
• The series of calixarene based receptors of ions and neutral
molecules were synthesized in the Institute of Organic
Chemistry NASU (see www.ioch.kiev.ua/calix )
• The sensitive calixarene based polymer films were prepared in
the Institute of Macromolecular Chemistry NASU
• The several chemosensor devices were constructed in the
Institute of Semiconductor Physics NASU.
STCU project #3643 “Development of chemosensor materials
and equipment for detection toxic substances and pollutants
in the environment”
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Targeted Market Segment
(Who needs it? How many will they need? What
price are they willing to pay, what do they pay now?)
• Food industry and agriculture
• Chemical industry
• Quality control of of perfumes and
beverages
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Competition
(Who is my competition? How will I beat the competition?)
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Competitive Matrix
Important product
or technology
characteristics
My company or
institute’s
product
Name of
Competitor #1
Name of
Competitor #2,
etc.
Key Characteristic
(a)
Key Characteristic
(b)
Key Characteristic
(c)
Key Characteristic
(d) (usually cost)
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Opportunities
(What I am seeking. Opportunity for joint work. Seeking
potential partners and licensees. And, How much will it
cost?)
We offer the Electronic Nose for:
• Food industry and agriculture
• Chemical industry
• Quality control of perfumes and
beverages
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Contact information
Iurii MATVIEIEV
+38 044 551-1628
+38 050 501-1393
[email protected]
National Academy of Sciences of Ukraine
Institute of Organic Chemistry
Kiev
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