A B CEM-C7-14 CEM-C1-15 CEM-C1-15 CEM-C1-15 Dex Dex U+SP U+SP+Dex CEM-C1-15 C ip SP c-Jun P c-Jun C ERK P ERK D USP USPD CEM-C1-15 CEM-C1-15 U+ip U+ip+Dex