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Cytochrome P450

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Case 1 Mr. L.P. is a 47 year-old man who presents to the E

BIOTRANSFORMATION OF XENOBIOTICS Overview       Phase I and Phase II enzymes Reaction mechanisms, substrates Enzyme inhibitors and inducers Genetic polymorphism Detoxification Metabolic activation Introduction  Purpose  Converts lipophilic to hydrophilic compounds 

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Drug metabolism and pharmacogenetics

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