Young Key Populations

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HIV and AIDS

Data Hub for Asia-Pacific Review in slides

Young Key Populations

Last updated: March 2015

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Data availability and data issues

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“The analysis carried out by the Commission shows that

over 95% of all new HIV infections among young people occur among most-at-risk adolescents

.”

Report of the Commission on AIDS in Asia. Redefining AIDS in Asia: Crafting an Effective Response (2008), p. 146.

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What do we need to know to prioritize populations for the AIDS response?

• HIV-related risk in populations

– Sexual risk: levels and frequency of unprotected vaginal and anal sex – Injection risk: sharing of needles

• HIV and STI prevalence of sub-populations • Sizes of higher risk and vulnerable sub-populations • Geographic location of risk populations

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Main data collection components of HIV/STI surveillance systems

• Size estimates of key populations • Reported HIV and AIDS cases • HSS - HIV sentinel surveillance (facility-based) • BSS/IBBS - Bio-behavioral surveys in key populations (or general population) • STI Surveillance

Additional strategic information sources:

• Mapping of sub-populations • Special surveys • Program M&E, other…

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What is different about surveying young key populations(YKPs)?

The ethical considerations needed to include minors in studies that ask questions that relate to their sexual behavior, use of drugs and other risk behaviors

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Ethical procedures for surveyed young populations

Ethical review and approval:

• Weigh community benefit • Ethics approval granted for a person of any age to participate • Surveillance deemed as non-research activity by the Ethics Committee • Surveillance does not require Ethics Committee Review •

Parental consent requirements:

• Parent/ guardian consent required • Parent/ guardian consent waivered • Consent from Dept. of Education or school principal sufficient •

Special adjustments for minors:

• Protection of respondents built into design and questionnaires • Sensitive sexuality questions removed for very young students • Strategies to ensure consent secured without coercion • Referral to appropriate services.

Only 9 out of 47 studies reviewed described ethical procedures specific for minors: Afghanistan, Cambodia, Indonesia, Lao PDR, Maldives, Pakistan, PNG, Thailand, Vanuatu

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Data need for young key populations

To understand how HIV affects young key populations…

• Surveys have to include enough of young key populations to yield meaningful results • Reports of surveys have to include the age disaggregated data and results

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We need age disaggregated data to understand the epidemic among young key populations…and do we have it?

Data availability of FSW in HIV sentinel surveillance surveys conducted between 2009 and 2013 0 Number of countries assessed 26 Bangladesh, Cambodia, China, India, Indonesia, Myanmar, Sri Lanka, Thailand, Viet Nam Conducted between 2009-2013 9 Survey report available 7 Bangladesh, Cambodia, India, Myanmar, Sri Lanka, Thailand, Viet Nam Age disaggregated data reported in global AIDS reporting Age disaggregated data available from survey reports 3 5 Bangladesh, China, India, Myanmar, Sri Lanka Cambodia, Myanmar, Viet Nam

9 Source: Prepared by www.aidsdatahub.org

based on National HIV Sentinel Surveys and www.aidsinfoonline.org

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Apart from the data reported in global AIDS reporting, availability of age disaggregated behavioural data for FSW is limited Data availability of FSW in behavioral surveys conducted between 2009 and 2013 Number of countries assessed 0 26 Conducted between 2009-2013 19 Afghanistan, Cambodia, China, Fiji, India, Indonesia, Japan, Lao PDR, Malaysia, Mongolia, Nepal, Pakistan, PNG, Philippines, RO Korea, Singapore, Timor Leste, Thailand, Viet Nam Survey report available 13 Afghanistan, Cambodia, Fiji, India, Indonesia, Lao PDR, Mongolia, Nepal, Pakistan, PNG, Philippines, Timor Leste, Viet Nam Age disaggregated data reported in global AIDS reporting 12 Afghanistan, China, Fiji, Indonesia, Japan, Lao PDR, Malaysia, Mongolia, Pakistan, PNG, Philippines, Viet Nam Age disaggregated data available from survey reports 6 Cambodia, Fiji, Mongolia, Nepal, Pakistan, Philippines

Source: Prepared by www.aidsdatahub.org

based on Behavioral Surveillance Surveys; Integrated Biological and Behavioral Surveys; and www.aidsinfoonline.org

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Age disaggregated HIV prevalence and behavioural data for young MSM is scarce, especially from survey reports Data availability from sentinel and behavioural surveys among MSM, 2009-2013 Number of countries 0 2 4 6 8 10 12 14 16 18 20 22 24 26 Conducted between 2009-2013 Survey report available Age disaggregated data reported in global AIDS reporting Age disaggregated data available from survey reports Conducted between 2009-2013 (a) Survey report available (b) Age disaggregated data reported in global AIDS reporting (c) Age disaggregated data available from survey reports 1 2 6 Bangladesh, China, India, Myanmar, Sri Lanka, 4 Bangladesh, India, Myanmar, Sri Lanka 6 Bangladesh, China, India, Myanmar, Sri Lanka, Viet Nam Myanmar 12 13 Mongolia, Philippines 20 a) b) c) Afghanistan, Bangladesh, Cambodia, China, Fiji, India, Indonesia, Japan, Lao PDR, Malaysia, Mongolia, Myanmar , Nepal, PNG, Philippines , Rep. of Korea, Singapore, Thailand, Timor-Leste, Viet Nam Afghanistan, Cambodia, Fiji, India, Indonesia, Lao PDR, Mongolia, Nepal, PNG, Philippines, Timor-Leste, Viet Nam Afghanistan, Bangladesh, Cambodia, China, Indonesia, Malaysia, Mongolia, Myanmar , Nepal, PNG, Philippines , Thailand, Viet Nam

11 Source: Prepared by www.aidsdatahub.org

based on HIV Sentinel Surveys; Bio-Behavioural Surveys; www.aidsinfoonline.org

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Only one in 3 countries that conducted HIV sentinel surveillance surveys among PWID reported age disaggregated data in survey reports Data availability of PWID in HIV sentinel surveillance surveys conducted between 2009 and 2013 0 Number of countries assessed 26 Conducted between 2009-2013 6 Bangladesh, China, India, Myanmar, Thailand, and Viet Nam Bangladesh, India, Myanmar, Thailand, and Viet Nam Survey report available Age disaggregated data reported in global AIDS reporting Age disaggregated data available from survey reports Gender disaggregated data reported in global AIDS reporting Gender disaggregated data available from survey reports 0 2 4 4 5 Bangladesh, China, India, Myanmar Myanmar and Viet Nam Bangladesh, China, India, and Viet Nam

12 Source: Prepared by www.aidsdatahub.org

based on National HIV Sentinel Surveys; Global AIDS Response Progress Reporting; and www.aidsinfoonline.org

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Less than one fifth of countries that conducted behavioural surveys among PWID reported age disaggregated data in survey reports Data availability of PWID in behavioral surveys conducted between 2009 and 2013 0 Number of countries assessed 26 Conducted between 2009-2013 11 Afghanistan, Cambodia, China, India, Indonesia, Malaysia, Nepal, Pakistan, Philippines, Thailand, Viet Nam Survey report available 8 Afghanistan, Cambodia, India, Indonesia, Nepal, Pakistan, Philippines, Viet Nam Age disaggregated data reported in global AIDS reporting Age disaggregated data available from survey reports Gender disaggregated data reported in global AIDS reporting Gender disaggregated data available from survey reports 1 2 8 9 Afghanistan, China, Indonesia, Malaysia, Nepal, Pakistan, Philippines, Thailand, Viet Nam Nepal, Philippines Afghanistan, China, Malaysia, Nepal, Pakistan, Philippines, Thailand, Viet Nam Philippines

Source: Prepared by www.aidsdatahub.org

based on Behavioral Surveillance Surveys; Integrated Biological and Behavioral Surveys; Global AIDS Response Progress Reporting; and www.aidsinfoonline.org

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Only 20 of 31 country HIV surveillance systems include key populations – half or less have a reasonable proportion of young key populations represented Number of countries 20 15 10 5 0 19 16 14 10 5 4 3 2 17 Known to include the key population Known to include YKAP Able to identify the proportion of YKAP YKAP represents ≥30% of the surveyed population 14 12 11 8 5 4 2 15 11 10 4 FSW MSW MSM TG PWID Review of HIV prevalence data (2005-2011) available from surveillance in 20 countries* * Afghanistan, Bangladesh, Cambodia, China, Fiji, India, Indonesia, Lao, Malaysia, Maldives, Mongolia, Myanmar, Nepal, Pakistan, Philippines, PNG, Sri Lanka, Thailand, Timor Leste & Viet Nam

Source: Prepared by www.aidsdatahub.org

based on National HIV Sentinel Surveillance and HIV Prevalence Reports ; Global AIDS Response Progress Reports- Country Reports (2012) ; UNGASS Progress Reports (2010).

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The same is true for behavioral surveillance Number of countries 19 14 10 5 0 18 17 14 10 6 6 4 2 Known to include the key population Known to include YKAP Able to identify the proportion of YKAP 17 YKAP represents ≥30% of the surveyed population 16 15 13 12 12 11 8 6 4 4 2 FSW MSW MSM TG PWID Review of behavioral data (2006-2011) available from surveillance in 19 countries* * Afghanistan, Bangladesh, Cambodia, Fiji, India, Indonesia, Lao, Malaysia, Maldives, Mongolia, Myanmar, Nepal, Pakistan, Philippines, PNG, Sri Lanka, Thailand, Timor Leste & Viet Nam

Source: Prepared by www.aidsdatahub.org

based on National Behavioral Surveillance Reports ; Global AIDS Response Progress Reports- Country Reports (2012) ; UNGASS Progress Reports (2010).

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Age of inclusion of YKPs in surveys of key populations, based on available data from survey reports HIV prevalence surveys

9-14yrs :

Maldives (FSW 13, MSM 10); Pakistan (MSW 13); PNG (FSW 14, MSW 9) –

15+yrs :

Cambodia (FSW 15, MSM 18); Lao (MSM, TG 15); Maldives (PWID 17); Myanmar (FSW, MSM, PWID 15); Nepal (FSW, MSM, PWID 16); Pakistan (FSW, Hijra 15); Viet Nam (FSW, MSM, PWID 16) –

18+yrs :

Afghanistan (FSW,MSM, PWID 18); India (FSW, MSM, TG, PWID 18); Pakistan (PWID 18); Malaysia (MSM,PWID 18)

Behavioral surveys

9-14yrs :

Maldives (FSW 13, MSM 10); Pakistan (MSW 13); PNG (FSW 14, MSW 9 ) –

15+yrs :

Bangladesh (FSW, MSW, MSM, TG, PWID 15); Lao (FSW, MSM, TG 15); Maldives (PWID 17); Myanmar (FSW, PWID 15); Nepal (FSW, MSM, PWID 16); Pakistan (FSW, Hijra 15); Sri Lanka (FSW, MSM 16, PWID 17); Timor Leste (FSW, MSM 16) –

18+yrs :

Afghanistan (FSW, MSM,PWID 18); Cambodia (FEW, MSM 18);India (FSW, MSM, TG, PWID 18); Pakistan (PWID 18); Malaysia (MSM,PWID 18) Source: Prepared by www.aidsdatahub.org

Reports 2012 to 2014; UNGASS Progress Reports (2010).

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Proportion of surveyed FSW, MSM and PWID who are under 25 years of age where data is available 35 Nepal

2012 FSW (22 Terai Highway ); MSM (Kathmandu Valley); PWID (Eastern Terai Highway)

Philippines

2013 FSW data is only for registered female sex workers

India

2006, people who inject drugs and men who have sex with men <20 –25 years old, calculated median value

Indonesia

2011

23 23 25 27 31 35 42 40 50 51 56 65 Myanmar

2008-2009 Men who have sex with men (Yangon and Mandalay-2009)

Maldives

2008

25 39 41 48 54 36 Pakistan

2011

26 78 43 Viet Nam

2012

62 30 86 Lao People's Democratic Republic

Service women (2011); Men who have sex with men <20 yr (2009)

50

100 per cent Source: Prepared by www.aidsdatahub.org

based on 1) Integrated Biological and Behavioural Surveys; 2) HIV Sentinel Surveillance Surveys; 3) Behavioral Surveillance Survey reports

Female Sex workers MSM PWID

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A large proportion of surveyed sex workers are under 25 years of age % 100 Proportion of sex workers who are under 25 years of age where data is available 100 % 80 60 FSW MSW TG SW 80 60 40 20 0 35 48 36 78 31 42 47 Nepal (2012) Pakistan (2011) Fiji (2012) 86 40 51 51 20 43 42 41 36 35 27 25 23 0 Lao PDR (2011) Philippines (2013) PNG (2010) Viet Nam (2012) Fiji (2012) Maldives (2008) Pakistan (2011) Nepal (2012) Indonesia (2011) India (2006) Myanmar (2008)

Source: Prepared by www.aidsdatahub.org

based on 1) Integrated Biological and Behavioural Surveys; 2) HIV Sentinel Surveillance Surveys; 3) Behavioral Surveillance Survey reports

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Available information on Size Estimates of young key populations is extremely limited!

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HIV prevalence and epidemiology

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610,000

young people (15-24) are living with HIV in 2013, 13% of adults (15+) living with HIV in Asia and the Pacific Number 900 000 Estimated number of young people (15-24) living with HIV, 1990-2013, Asia and the Pacific 320,000 young female (15-24) 600 000 300 000 0 1990 1995 370,000 young male (15-24) 2000

Source: Prepared by www.aidsdatahub.org

based on UNAIDS estimates 2013

2005 290 000 320,000 2010 2013 Percent decrease between 2005 and 2013 Male -14% Female -17%

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Estimated HIV prevalence among young people (15-24), 2013 Young females (15-24) (%) Young males (15-24) (%) Afghanistan Bangladesh Bhutan Cambodia Fiji Indonesia Lao PDR Malaysia Maldives Mongolia Myanmar Nepal Pakistan Papua New Guinea Sri Lanka Thailand Viet Nam <0.1

<0.1

0.1

0.2

<0.1

0.5

<0.1

<0.1

<0.1

<0.1

0.3

<0.1

<0.1

0.2

<0.1

0.3

<0.1

<0.1

<0.1

<0.1

0.2

<0.1

0.4

<0.1

0.2

<0.1

<0.1

0.2

<0.1

<0.1

0.1

<0.1

0.3

<0.1

22 Source: Prepared by www.aidsdatahub.org

based on www.aidsinfoonline.org

HIV and AIDS

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Young sex workers are getting infected with HIV!

HIV prevalence among sex workers by age group, countries where the data is available from 2010- 2013 25 20 15 10 5 0 1,7 0 Countries with HIV prevalence < 5% among SW < 25 years 0,2 0 0,4 0,2 0,4 0,2 0,3 0,3 2,1 0,8 5,0 1,1 3,0 1,7 1,4 2,1 2,5 2,1 Countries with HIV prevalence > 5% among SW < 25 years 20,9 9,2 9,4 7,1 8,02 12,7 <25 yr 25+ yr

* FSW only ** FSW and MSW *** FSW and TG SW ++ MSW and TG SW 23 Source: Prepared by www.aidsdatahub.org

based on www.aidsinfoonline.org

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Young MSM are getting infected with HIV!

35 30 25 20 15 10 5 0 HIV prevalence among MSM by age group, countries where the data is available from 2009- 2013 Countries with HIV prevalence < 5% among MSM < 25 years 30,4 Countries with HIV prevalence > 5% among MSM < 25 years 1,1 0,0 0,9 0,0 0,6 0,8 4,1 1,1 5,3 1,9 6,4 1,9 6,7 2,0 4,8 2,5 3,0 4,9 3,5 16,3 5,3 7,3 5,6 9,8 6,1 16,0 6,2 12,4 11,1 8,8 10,0 <25 yr 25+ yr

24 Source: Prepared by www.aidsdatahub.org

based on www.aidsinfoonline.org

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Young PWID are getting infected with HIV!

HIV prevalence among PWID by age group, countries where the data is available from 2010- 2013 Countries with HIV prevalence < 5% among PWID < 25 years Countries with HIV prevalence > 5% among PWID < 25 years 60 50 40 30 20 10 0 1,1 0,7 13,0 1,1 5,1 2,7 6,5 3,7 19,4 4,8 7,7 5,3 43,9 11,6 20,7 11,7 25,3 25 25 33,9 48,1 41,2 25+ yr <25 yr

25 Source: Prepared by www.aidsdatahub.org

based on www.aidsinfoonline.org

Risk behaviours

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Proportion of young people (15-24) who had sex before the age of 15, countries where data is available, 2006-2011 Palau (2009) Afghanistan (2012) Bangladesh (2011) India (2009) Marshall Islands (2006) Papua New Guinea (2009) Vanuatu (2010) Japan (2009) Nepal (2011) Micronesia (Federated States of) (2007) Tonga (2008) Philippines (2008) Timor-Leste (2009) Tuvalu (2009) Kiribati (2011) Sri Lanka (2006) Thailand 2009 Bhutan (2012) Myanmar (2011) Cambodia (2013) Viet Nam (2013) Pakistan (2007) Indonesia (2011) Mongolia (2011) (%) 50 40

Source: Prepared by www.aidsdatahub.org

based on www.aidsinfoonline.org

30 Young male (15-24) Young female (15-24) 14.8

13.9

10.7

10.1

9.7

9.4

8.9

8.6

7.0

6.5

5.5

2.1

1.8

1.6

1.6

1.4

1.3

1.0

0.8

0.6

0.5

0.4

0.2

0.2

20 10 0 2,3 3,1 0,9 3,1 0,5 0,5 0,3 0,9 0,3 2,8 7,6 8,3 10 9,6 17,4 17,3 16,5 14,2 14,6 13,8 20 23,1 30 35,5 40,1 40 50

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People do start risk behaviors when they are young … ≥ 25 yr

Source: Prepared by www.aidsdatahub.org

28 UNGASS Progress Reports (2010).

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Condom use at last sex among sex workers by age group, countries where the data is available, 2007-2013 100 80 60 40 20 0 88 84 83 89 90 82 91 92 92 95 96 86 62 57 53 51 37 34 43 49 53 65 67 70 75 86 88 88 91 93 93 94 96 81 < 25 yr 25+ yr * FSW only ** FSW and MSW *** FSW and TG SW ++ MSW and TG SW

29 Source: Prepared by www.aidsdatahub.org

based on www.aidsinfoonline.org

HIV and AIDS

Data Hub for Asia-Pacific

Condom use among young MSM is generally lower than their older counterparts Condom use at last anal sex among MSM by age group, countries where the data is available, 2007-2013 100 88 92 79 76 78 80 69 66 69 69 61 62 68 58 60 52 45 40 70 72 76 84 86 91 24 60 61 64 66 69 65 18 20 38 44 45 24 17 0

Source: Prepared by www.aidsdatahub.org

based on www.aidsinfoonline.org

< 25 yr 25+ yr

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HIV and AIDS

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Low level of condom use among PWID including young PWID! Condom use at last sex among PWID by age group, countries where the data is available, 2007-2013 < 25 yr 25+ yr 100 77 80 52 60 45 47 50 40 43 41 33 40 27 79 23 17 56 20 13 13 15 22 25 40 43 43 47 47 49 43 0

31 Source: Prepared by www.aidsdatahub.org

based on www.aidsinfoonline.org

HIV and AIDS

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Young PWID’s safe injection practice compared to that of older counterparts 100 Proportion of PWID reported using sterile injection equipment at last injection by age group, countries where data is available, 2007-2013 98 94 97 89 87 84 80 79 80 70 69 67 72 69 60 98 40 32 35 71 73 82 83 85 94 97 57 58 63 64 58 20 41 28 0

Source: Prepared by www.aidsdatahub.org

based on www.aidsinfoonline.org

< 25 25+

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Vulnerability and HIV knowledge

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% Proportion of sex workers with comprehensive HIV knowledge, by age group, countries where data is available, 2007-2009 100 80 60 40 20 0 Total <25 yr 25+ yr

Source: Prepared by www.aidsdatahub.org

based on UNGASS Country Progress Reports 2006,2008 and 2010

* Manipur ** Kathmandu

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HIV and AIDS

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Proportion of MSM with comprehensive HIV knowledge, by age group, countries where data is available, 2007-2013 % 100 80 60 40 20 0 Total <25 yr 25+ yr

Source: Prepared by www.aidsdatahub.org

based on 1.UNAIDS Report on The Global AIDS Epidemic, 2010; 2. UNGASS Country Progress Reports ; 3. Integrated Biological and Behavioural Survey Reports

* Manipur

35

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Proportion of PWID with comprehensive HIV knowledge, by age group, countries where data is available, 2007-2009 % 100 80 60 40 20 0 Total <25 yr 25+ yr * Manipur ** Kathmandu

Source: Prepared by www.aidsdatahub.org

Epidemic

National response

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Laws and regulations that allow adolescents to seek services without parental/spousal consent, countries where data is available Country (reporting period) Contraceptive services except sterilization HIV testing and counselling services Harm reduction services for young PWID Cambodia (Dec-2013) India (Feb-2014) Indonesia (Jan-2014) Kiribati (Jun-2014) Lao PDR (Dec -2013) Malaysia (Dec -2013) Myanmar (Feb- 2014) Nepal (Jan-2014) Pakistan (Feb-2014) Papua New Guinea (Jan-2014) Philippines (Mar-2014) Solomon Islands (Dec-2013) Sri Lanka (Jan-2014) Timor Leste (Jan-2014) Vanuatu (Dec -2013) Viet Nam (Jan-2014)

Source: Prepared by www.aidsdatahub.org

based on Department of Maternal, Newborn, Child, and Adolescent Health (WHO) at http://www.who.int/maternal_child_adolescent/documents/countries/indicators/dashboards/en/ (accessed Feb 4, 2015)

Yes No No information

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Compared to their older counterparts, less young key populations being reached by prevention are programmes less young key populations have access to HIV testing services and approximately 1 in 4 young key populations do not know their HIV status

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Lower prevention coverage among young sex workers under 25 years, 2007-2013 100% 80 60 40 20 0 Proportion of sex workers reached with HIV prevention 31 5 programmes in the last 12 months, 2007-2013 85 79 70 91 68 65 49 56 55 42 59 54 48 15 34 19 33 39 40 42 29 45 13 14 70 65 85 80 65 42 25+ yr < 25 yr * FSW only ** FSW and MSW *** FSW and TG SW ++ MSW and TG SW +++ FSW, MSW and TG SW

40 Source: Prepared by www.aidsdatahub.org

based on www.aidsinfoonline.org

HIV and AIDS

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Proportion of MSM reached by prevention programmes, by age group, 2008-2013 Proportion of MSM reached with HIV prevention programmes in the last 12 months, 2008-2013 100% 73 78 78 80 80 71 60 52 47 61 62 64 63 68 76 80 61 55 40 30 49 49 21 25 29 43 39 20 18 20 21 0 12 25+ yr < 25 yr

41 Source: Prepared by www.aidsdatahub.org

based on www.aidsinfoonline.org

HIV and AIDS

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Less than 1/3 of young sex workers know their HIV status 100 % Proportion of sex workers who received an HIV test in the last 12 months and know their results, 2007-2013 73 80 57 57 60 46 48 36 39 39 40 28 31 36 20 15 20 7 10 8 21 25 27 28 30 38 40 43 50 68 27 0 4 6 10 11 21 < 25 yr 25+ yr * FSW only ** FSW and MSW *** FSW and TG SW ++ MSW and TG SW

Malaysia and Indonesia data is not included in regional median calculation since the denominators of reported proportion for HIV testing coverage do only those who answered HIV testing related questions Source: Prepared by www.aidsdatahub.org

based on www.aidsinfoonline.org

HIV and AIDS

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1 in 4 young MSM surveyed in the region do not know their HIV status….

100 % Proportion of MSM who received an HIV test in the last 12 months and know their results, 2008-2013 80 69 51 60 48 45 51 41 37 36 36 40 33 22 20 20 13 13 20 0 7 7 7 8 12 15 17 22 24 33 36 38 39 45 56 63 24 < 25 25+

Source: Prepared by www.aidsdatahub.org

based on www.aidsinfoonline.org

Malaysia and Indonesia data is not included in regional median calculation since the denominators of reported proportion for HIV testing coverage do 43 those who answered HIV testing related questions

HIV and AIDS

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Only 1 in 5 young PWID in the region know their HIV status 100 % Proportion of PWID who received an HIV test in the last 12 months and know their results, 2007-2013 78 80 60 40 25 25 23 28 38 34 48 25 18 21 20 0 5 4 6 6 9 8 15 19 20 21 22 26 27 36 54 79 21 < 25 yr 25+ yr

Source: Prepared by www.aidsdatahub.org

based on www.aidsinfoonline.org

Indonesia data is not included in regional median calculation since the denominator of reported proportion for HIV testing coverage do not reflect total surveyed PWID and the denominator represent only those who answered HIV testing related questions 44

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THANK YOU

slides compiled by www.aidsdatahub.org

Data shown in this slide set are comprehensive to the extent they are available from country reports. Please inform us if you know of sources where more recent data can be used. Please acknowledge www.aidsdatahub.org

if slides are lifted directly from this site

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