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MOI-106 Regalia™SC (formerly Milsana®) Julie Versman, VP Marketing 530-750-2800 [email protected] Marrone Organic Innovations Founded 2006 by Pam Marrone, Davis CA Natural products that focus on unmet needs for weed, pest and plant disease management. Product discovery from 1) in-house screening 2) in-licensing A rich pipeline of products in development with applications for specialty crops MOI-106 Regalia™SC Fungicide Overview Source: Extract from giant knotweed Reynoutria sachalinensis (REYSA). Formulation: Suspension Concentrate (SC) Target pathogens controlled (edible crops and ornamentals): Powdery mildew, Gray mold, Rust Bacterial blight, Bacterial canker, Bacterial spot, Target spot, Bacterial speck, Early blight and Late blight of tomato Overview continued Mode of Action: Induction of plant defense responses. – 5 x Enzymes of the phenolic pathway – increased production of phytoalexins Registration status -Has EPA crop and non-crop registrations as biochemical biopesticide. (grapes, cucurbits, strawberries, walnuts, peppers, lettuce, tomato, citrus) -Has California crop and non-crop label (grapes, cucurbits, strawberries, walnuts, peppers, lettuce) MOI-106 Regalia™SC - Use/Timing Apply at the rate of 0.5-1.0% in 50 to 100 gallons of water per acre. Add wetting agent at recommended label rate Use the spray mixture preventatively at the 4-6 leaf plant stage and repeat spraying every 7-14 days depending on disease pressure. Recommend 0.5% v/v rate in a tank mix with properly labeled rates of Maneb, Mancozeb, or copper products for broad spectrum control of bacterial speck, target spot, tomato late blight and gray mold. Regalia™SC on Food Crops Grapes Cucurbits Strawberries Lettuce Walnuts Tomatoes Peppers Citrus Diseases: Powdery Mildew, Botrytis, Downy Mildew, Gummy stem blight Bacterial blight, Bacterial canker, Bacterial leaf spot, Target spot, Bacterial speck Tomato late blight & early blight, Regalia™SC on Ornamentals Begonias Lisianthus Salvias Crape myrtle Petunias Snapdragons Freesias Poinsettias Zinnias Gerbera Roses Diseases Powdery Mildew (Oidium spp) Gray Mold (Botrytis cinerea) Rust (Puccinia antirrhini) Field Data Regalia vs. Powdery Mildew of Lettuce Mike Matheron and Martin Porchas, U of Arizona, 2001-2002 3 .5 Mean Disease Rating 3 .0 2 .5 2 .0 1 .5 1 .0 0 .5 0 .0 Regalia M ils ana .2 5 gal + Rally 4 0 W, 0 .1 lb, A c tigard 5 0 WG , T ween 2 0 , 1 9 ml, 2 ,4 1 ,2 ,3 ,4 0 .0 2 5 lb, 1 ,2 ,3 ,4 Serenade WP , 6 .0 lb, 1 ,2 ,3 ,4 Q uadris 2 .0 8 SC , U ntreated C ontrol .2 5 lb, 1 ,3 Treatment, Rate/A, Treatment Dates Treatments were applied with a tractor-mounted boom sprayer that delivered 50 gal/acre at 100 psi. Treatment dates: 1=Jan 11; 2=Feb 1; 3= Feb 13; 4=Feb 27 Field Data Regalia vs. Early Blight on Tomato Pam Roberts, U of FL, 2007 12.00 % Disease Severity 10.00 8.00 6.00 4.00 2.00 0.00 .5% v/v Manzate Pro-Stick Serenade Max 1 lb w/Manzate Pro75 DG 2 lb w/Cuprofix Ultra 40 Stick 75 DG 2 lb, w/Kocide 3000 2 lb, DF 1.25 lb. Kocide 3000 2 lb. Bravo Weather Stik 6F 3 pt, Quadris 6 fl oz. Volume=66 gal/A Applications were made weekly for 14 weeks Kasumin 64 OZ/ 100 gal w/Kocide 3000 2 lb, Manzate Pro-stick 75 DG 2 lb, Bravo Weather Stik 6 F 3 pt, Quadris 6 fl oz. Cuprofix Ultra 40 DF 1.5 lb w/Penncozeb 75 DF 2 lb, Bravo Weather Stik 6F 3 pt, Quadris 2.08SL 6 FL oz. Untreated Control Coming soon: Organic, Concentrated (5%) formulation of Regalia NEW: MOI 104 - Hinokitiol-based broad-spectrum fungicide for Botrytus control… Potential IR-4 Projects Test Regalia SC as part of IPM programs in ornamentals, vegetables, fruit, vines (Botrytis, mildews, bacterial diseases. Other diseases ? Test Regalia SC on turf diseases Test efficacy against other pathogens, such as oomycetes (Phytophthora spp.) Bridging studies to organic formulation MOI-106 Regalia™SC (formerly Milsana®) Julie Versman, VP Marketing 530-750-2800 [email protected] www.MarroneOrganicInnovations.com