Transcript PHAKIC

PHAKIC IOL’S ( pIOL’S ) IN CORRECTING HIGH MYOPIA

By: H.R. ZIAI MD.

Esfand 1391 Isfahan

HISTORY

1950s

: First ideas formed •

1988

Bikoff : Angle supported PMMA, ZB5M & MA20, by •

But

: • Discontinued because of complications ( corneal edema, iritis ,… )

HISTORY

• •

1988

: First phakic iris – clawed IOL introduced for myopia by Worst • •

1998

: Artisan – Worst by OPHTEC • Verysise Then changed it’s name to Artisan – and it’s flexible form to Artiflex

HISTORY

1987:

First PC pIOL or sulcus support pIOLs introduced : • • - Phakic Refractive Lens ( PRL ) by CIBA VISON .

And then

: • • - Implantable Contact Lens ( ICL ) or Implantable Collamer Lens ( ICL ) • • - Collamer is a copolymer of hema ( 99% ) and porcine collagen ( 1% )

CLASSIFICATION OF pIOLS

• • •

Ant.Chamber pIOLS ( AC pIOLS) -

Angle supported

1) PMMA 2) Foldable

• • • • Clawed

1)PMMA 1)Foldable

Post.Chamber pIOLS ( PC pIOLS )

(or sulcus supported ) - Iris – \\\

INDICATIONS

High Myopia

• - Myopia > -8.00 to -10.00 D • • - Stromal bed < 300µ after laser ablation • - Keratometry < 34-36D after laser ablation

FDA Approval for Artisan/Artiflex

• - Myopia : -5.00 to -20.00 D • - Ast. < 2.5 D • - Age > 21 y • - ACD > 3.2 mm

FDA Approval for ICL :

• - Myopia : -3.00 to -20.00 D • - Ast.< 2.50 D • - Age 21 - 45 y • - ACD > 3.00 mm

High Hyperopia

• • • • - Keratometry > 50 D after laser ablation • - Available pIOLS : ICL : Up to +20.0 D Artisan : Up to +12.00

High Ast.

• - Laser ablation is the Tx of choice for Ast. up to 4.00 – 5.00 .

• - PIOLS are available too .

CONTRAINDICATIONS

• • - Any intraocular pathology ( Cat. , Glaucoma , NVI , Uveitis , … ) • - ↓ ACD • - ↓ Diameter

ADVANTAGS OF pIOLS

• - Rang of correction >> Laser • - Easy technique ( Like Cat. Surgery ) • - Less expensive instruments than Laser • - Removable • • • - No ↓ in contrast sensitivity even : ↑ Compared with spectacle -More predictable

DISADVANTAGES OF pIOLS

• - All intraocular risks • - Large incision ( in PMMA types ) • - Limitation in hyperopia due to small ant. segment • - Irreversible complication

PRE-OP EVALUATION

• - Power of IOL • - Diameter of IOL for angle or sulcus supported IOLs • - ACD • - Specular microscopy • - Optic size in correlation to scotoptic pupil size • - All other rutin evaluation before cat. surgery

Cont.

But :

• •

Main challenge in angle or sulcus supported pIOLs is

:

“ Sizing IOL diameter”

• Through Angle-to-angle • And ciliary sulcus diameter

Cont.

For angle supported pIOLS

• - 0.5 – 1.00 mm add to w-to-w measured manually or by orbscan, although not always correct .

• - Use of OCT/UBM

Cont .

Note:

• If diameter measured horizontally the lens must implanted horizontally; if implanted vertically, it causes Decenteration , Ovalization , Iritis , Glaucoma.

Cont.

• For PC pIOLS ( sulcus supported ) • - Add 0.50 – 1.00 mm to horizontal W-W • - New ultrasound techniques like Artemis & UBM

ANGLE SUPPORTED pIOLS

Surgical Technique (important points)

• -Incision , 2- 6.5mm (based on type ) • - Sup. approach ( more common ) • - Retrobulbar avoided ( glob perforation ) • - IOL dialled to the best pupil-optic matching

Cont.

• - Surgical PI • - OVD irrigated meticulously • - Pilo 2 ( useful , but may decentered pupil

Complications

) • -

Haloes and Glare

: more com complication ( 20 % • more in 1th year,

but

: ↓ over time •

- Pupil ovalisation

( 7-22% ) ( if oversized ) •

- Iris retraction and atrophy

Cont.

Endothelial cell damage:

• -Surgical trauma Presence of IOL - 5 7% in 1th year and less in next years Too small size : ↑ damage

Cont.

• • • •

- ↑ IOP

- Transient , 2’ to OVD - Topical CS - Pupilary block • • •

- Uveitis :

4.5% - Usually transient , 2’ to iris manipulation - In over sized IOL , may chronic, causing glaucoma cat. , PAS, Iris damage , …

Cont.

• • • •

- Cataract

- Less common than PC pIOL - Caused by trauma , uveitis - Age > 40 y at time of surgery • • - AL > 30 mm •

- RD

: 3% If pIOL have additive risk for RD over the myopia??

Cont.

• • • • • •

Rare complications

- Corneal decompensation - Urretis – Zavalia synd.

- Malignant glaucoma - Endophthalmitis - Hyphema

IRIS FIXATED pIOLs

General information of Artisan

• - 0.5 mm vault ( 0.8 mm distance between IOL & crystalin lens) • - Diameter : 8.5 mm • - Optic : 6.5 & 6.0 mm • - Center :0.2 mm thickness

Indications ( FDA ) :

• - Myopia • - Hyperopia • - RE After PK • - Sever anisometropia in children • - Aphakia • - KCN • - Progressive high myopia in psudophakic children

Complications

• -

Glare & haloes

: 0-9% more in small optics ( 5mm ) and Large pupil ( > 5.5 mm ) • -

AC inflammation

: 0.5% • -

Pigment dispersion :

2” to poor enclavation • -

Crystalin lens rise

: like Hyeperopia ( Artiflex > Artisan ) because of step in optic haptic junction

Cont.

• •

Endothelial cell loss

- Intraoperative trauma ( main cause ) • • - more in first 6m post op.

• - ACD < 3.2 → ↑ risk • •

Glaucoma

- Usually transient - OVD , CS , pigment , inflammation

Cont.

Cataract

: 3% - NS • - Age > 40 at implantation time →↑risk • - AL > 30 mm →↑ risk • • • •

Other complications

- Hyphema - Intermittent myopic shift - RD

PC PIOLs ( SULCUS SUPPORTED )

- PRL

: Silicon , hydrophobe •

- ICL

: Hydrophyl , biocompatible , permeable

Complications

• • -

Glare & halos

8.4 % , ↓ over time • -

Flare

; 27%, Up to 2y • • • • •

-Cataract

- The major concern - 0.6 – 3 % - Traumatic contact , metabolic disturbance - Ant. sub capsular

Cont.

Pigment dispersion & deposition

• - Iris rubbing • - ↑ Size ( ↑ Vault ) →↑ dispersion

• • • •

Glaucoma

- 2’ to pigment dispersion - Angle closure - Pupilary block ( if fibrin formed ) • • • - ICL > PRL •

Decenteration

: The most complication - Small size IOL

, difficult problem

- Even sometime dislocation into vitreous cavity

Note

: • In PC pIOL

, vault

is of

critical importance

• - ↑ Vault → ↑ Pigment dispersion • - ↓ Vault → ↑ Cataract

BIOPTICS

Implantation of pIOL followed by Laser ablation

• - In case of extremely myopia , high Ast. , lens power not available.

• - Safe and effective

FEW SELECTED POINTS

• - PIOLs have been used successfully for post PK Ast.

• - Artisan induces HOA less than APT because of reserving prolate shape of cornea.

• - Toric pIOL + CXL successfully have been used for correcting RE in mild to moderate KCN & PMD.

Cont.

• - AC pIOLs have been used for TX of children with sever myopic anysometropia ( > -8.00 ) that resist or no cooperative for traditional amblyop therapy with encouraging results .

CONCLUSION

• • • • •

Compared with corneal laser ablation, pIOLs are excellent in :

- Predictability - Efficacy - Safety - Quality of vision

شزوپ ضرع نمض

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