The Rectum and You - Welcome to my website :-)

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Transcript The Rectum and You - Welcome to my website :-)

The Rectum and You

Robert Theobald III, D.O.

Vein Associates P.A.

Napolean

Jimmy Carter

George Brett

Hemorrhoids

 Cushions of tissue and varicose veins located in and around the rectal area  Usually swollen and inflamed due to precipitating factors  Factors include constipation, diarrhea, pregnancy, straining, aging, and anal intercourse

Hemorrhoids

 Approximately 89% of all Americans at some time in their lives  Over 2/3 of healthy people report having hemorrhoids  Hemorrhoids tend to become worse over the years, never better, unless intervention ensues

Hemorrhoids

 They are located both inside and above the anus (internal) or under the skin around the anus (external)  Hemorrhoids arise from congestion of internal and/or external venous plexuses around the anal canal  Are classified into four degrees

Hemorrhoids-Classifications

    1 st Degree: Bleeding occurs, but do not prolapse outside the anal canal 2 nd Degree: Prolapse outside the anal canal upon defecation, but retract spontaneously 3 rd Degree: Require manual reduction after prolapse 4 th Degree: Can not be reduced, because of strangulation 

This is a medical emergency!

Hemorrhoids

Hemorrhoids

 The major drainage of the hemorrhoidal plexus is through the

superior hemorrhoidal vein

, which drains into the inferior mesenteric vein and the portal system  Hemorrhoidal veins have no valves  Valveless veins exert maximal pressure at the lowest point

Hemorrhoids

 Any process that impairs venous return will promote stasis  Can be produced by either systemic or by portal venous hypertension (CHF or cirrhosis)  Intra-abdominal pressure also impairs venous return (ascites, exercise, pregnancy, straining, and tumors)

3

rd

Degree Prolapse

4

th

Degree Prolapse

Hemorrhoids

The most significant symptom is rectal bleeding!

 Usually bright red  Internal hemorrhoids are

NOT

painful  Bleeding can be significant because of an arteriovenous fistula formation in plexus  Other symptoms are prolapse, pruritis, and perianal edema

Perianal Edema

Hemorrhoid Treatment

 Treatment starts conservatively  Hydrocortisone Cream 2.5%  Anusol HC Suppositories  Rubber-Band Ligation  Sclerotherapy (5% phenol)  Infra-Red Coagulation  Surgery

Hemorrhoidectomy

Thrombosed External Hemorrhoids

 Thrombosed hemorrhoids are an acute and very painful problem that develops rapidly  Typically a perianal mass develops which is painful to palpate (and look at)  The lesion is due to sudden clot formation in one of the subcutaneous or submucosal veins

Thrombosed External Hemorrhoids

Thrombosed External Hemorrhoids

 The diagnosis is easy to make by the violet discoloration of the lesion  The overlying tissue is tense and shiney  Treatment is with excision of the clot  The body will eventually reabsorb the clot, but might takes weeks  Easier to excise after a few days  Adherence may occur if not excised within a few days

Abscesses

 A perianal abscess is a collection of pus in one of the anatomic spaces of the anal region  The perianal anatomy is defined by the sphincter and the

levator ani

muscles  The Iliococcygeus, Pubococcygeus, and Puborectalis

Abscesses

 Abscesses can be classified according to location  Perianal, Supralevator, Intersphincteric  The most common location is perianal  It results from a blockage of the anal glands located just outside the anus

Abscesses

 According to the crypto-glandular theory, they often develop from cryptitis which may be associated with an enlarged papillae in the anal canal  It starts as a cellulitis with only swelling and erythema  Finally, the infecting organisms burrow in the anal glands producing the abscess

Abscesses

 The microorganisms are not specific or unique  They are usually polymicrobial  More than 90% will include

E. coli

 Other organisms include

streptococci, staphylococci,

and a variety of anaerobic bacteria

Abscesses-Symptoms

 The patient will present with fever, local inflammation, and pain  The initial manifestation is fever followed by pain  In 24-48 hours a fluctuant mass will appear  An abscess in the intramuscular space may be difficult to diagnose and treat  Clinical assumption is needed to treat appropriately

Abscess

Abscesses

 Treatment consists of surgically draining the infected cavity  A cruciate incision is made to allow pus to drain for a few days  Sometimes a catheter is left in the incision to assure adequate drainage  A fistulous tract can arise if the abscess is not treated properly

Fistula

 Most fistulas begin as an anorectal abscess  Anal fistulas is an abnormal passage or communication between the interior of the anal canal or rectum and the skin surface  Rarer forms may communicate with the vagina, large bowel, and bladder

Fistula

Fistula-Symptoms

 Are usually a purulent discharge and drainage of pus or stool near the anus  Can irritate the outer tissues causing itching and discomfort  Pain occurs when fistulas become blocked and abscesses recur  Flatus may also escape from the tract

Fistula

 Fistulas can be difficult to diagnosis  A probe must be passed between the opening of the skin ’ s surface and the interior opening 

Goodsall ’ s Rule

can be helpful  Other causes include tuberculosis, inflammatory bowel disease, and cancer

Crohn’s Fistula

Fistula-Treatment

 Fistulas last until surgically removed  Excision of the complete tract is called a fistulectomy  Sometimes a seton is placed in the tract to elicit an inflammatory reaction in the tissue resulting in closure  80% success rate with surgery  Remicade (infliximab) for persistent disease

Fissures

 An anal fissure is a tear causing a painful linear ulcer at the margin of the anus  Can cause itching, pain, or bleeding  80% of fissures occur in the posterior midline  15% of fissures occur in the anterior midline  5% of fissures occur either right or left lateral – Fissures that occur laterally think of Crohn ’ s, tuberculosis, lymphoma, leukemia, anal cancer, syphilis, and trauma

Fissures

 When an anal fissure is suspected, physical examination is diagnostic  The exam may be difficult due to pain and sphincter spasm 

The triad consists of a sentinel skin tag, a fissure and a hypertrophied papilla

Fissures

Fissures-Treatment

  Treatment for superficial fissures includes

Anusol HC or Canasa (mesalamine) suppositories

If suppositories don ’ t heal fissure, then

nitroglycerin cream 0.2%

is used (headaches are major side-effect)  If not responding to pharmacotherapy or chronic fissure, then surgery is recommended

Fissures-Treatment

 Surgery consists of a

fissurectomy and sphincterotomy

 Helps the fissure to heal by preventing pain and spasm which interferes with healing  90% of patients will improve with the surgery  Very small chance of anal incontinence

Auto-colonoscopy

Pilonidal Cysts

 The term pilonidal was derived from the Latin

pilus

meaning hair and

nidus

meaning nest  The pathogenesis is unknown, but the most common theory is that they are a result of an embryonic malformation and results in a remnant of a neurocanal  Men are more likely than women to have the cysts at a ratio of 4 to 1

Pilonidal Cysts

 Infection of a pilonidal cyst is most commonly seen between puberty and age 30  Hair growth and secretion of sebaceous glands reach their peak   Some suggest that trauma to the gluteal area to be an important predisposing factor In WWI it was known as

Jeep Rider ’ s Disease

Pilonidal Cysts

 Unless they become infected or inflamed, they are asymptomatic  When a cyst becomes infected, an abscess can develop, usually lateral or superior to the gluteal cleft and over the coccyx  As the process becomes chronic, a fistula develops and creates a sinus tract 

Diagnosis can be made with pilonidal pores which are 2 or more openings located between the gluteal cleft

Pilonidal Cysts

Pilonidal Cysts

Pilonidal Cysts-Treatment

The only way to cure pilonidal cysts is surgery

 The first episode can be treated with antibiotics (

Keflex or Augmentin

)  If recurrent, then surgery is performed  Open-technique is most successful  Other techniques include closed, marsupialization, and Z-plasty

Condylomata Acuminata

 Condylomata Acuminata (anal or perianal warts) are the most common sexually transmitted disease of the anus and rectum  Human papillomavirus (HPV) is responsible  Over 40 subtypes of HPV 

Most common 6 and 11

16, 18, 31, and 32 are associated with squamous cell carcinoma

Condylomata Acuminata

 CDC reports a 500% increased in the incidence from 1981; 1/7 Americans  Are epithelialized, raised wartlike lesions that arise alone or more often in groups  They can range from a few millimeters to a cauliflower-like lesion  Can occur in combination with genital lesions  Mode of transmission is sexual intercourse, auto-inoculation may occur  Rarely bleed or painful, mostly pruritis

Condylomata Acuminata

 Although perianal condylomata can be seen in women and heterosexual men, typically the patients are homosexual males  CDC reports that 60-70% of homosexual men have condylomata  Women have increased risk of cervical carcinoma with HPV infection

Condylomata Acuminata

Condylomata Acuminata

Condylomata Acuminata

Condylomata Acuminata

Condylomata Acuminata

 Successful therapy requires accurate diagnosis and eradication of all warts  All patients undergo anoscopy and genital examination  Once identified, there are many different treatments depending on disease progression  Each treatment has advantages and disadvantages

Condylomata Acuminata

 The treatment options consist of

excisional, destructive, immunotherapy, and chemotherapy

 Condylomata can be excised either in the office with local anesthesia or in the operating room  Preservation of the anoderm and anal canal mucosa to minimize pain and healing time  The rate of recurrance is less than 10%

Condylomata Acuminata

Podophyllin

is a resin that is cytotoxic to condylomas and very irritating to normal skin  Can not be applied to anal canal lesions  Local complications include necrosis, fistula, and anal stenosis 

Electrocautery, Cryotherapy, and Lasers

are also used with frequency

Condylomata Acuminata

 Two therapies that are more commonly practiced today are

interferon injections and Aldara (imiquimod) cream

  Both therapies are very potent with many side-effects LFT ’ s should be checked routinely with interferon injections  Aldara should be used every other day, because it can burn normal tissue and make it necrotic

Pruritis Ani

Pruritis Ani

 More common in males than females  Symptoms include itching, burning, and irritation  Close examination of the perianal area is required; ulcerations and excoriation  Can be associated with other diseases – Infections (fungal, parasitic, bacterial) – Irritants (soaps, coffee, ETOH, detergents) – Dermatologic (psoriasis, dermatitis, pemphigus) – Systemic disease (diabetes, SLE, liver dx)

Pruritis Ani

 Treatment – Avoiding the offending agents – Creams (analpram lotion/cream 2.5%) – Topical Steroids – Corona ointment (lanolin/bees wax based)

Anal Cancer

 Very uncommon cancer, accounting for only 4% of all cancers of the lower GI tract  Anal cancer is on the rise due to individuals with HPV  The majority of patients are women in their seventh decade who present with bright red bleeding and pain

Anal Cancer

 Anal cancer is often curable  3 major factors include site, size, and differentiation 

Squamous cell carcinomas

make up the majority of all primary cancers of the anus  The others are adenocarcinoma, verrucous carcinoma, and malignant melanoma  Colorectal cancers are primarily

adenocarcinoma

Squamous Cell Carcinoma

Anal Cancer-Treatment

 Surgery is a common way to diagnose and treat anal cancer 

Local resection

takes out only the cancer, it spares the internal anal sphincter muscle 

Abdominoperineal resection (APR)

removes the anus and the lower part of the rectum by cutting into the abdomen and the perineum  With an APR, the patient will have a colostomy

Anal Cancer-Treatment

 Radiation therapy and Chemotherapy are used together to shrink tumors  All anal cancers respond very well to this combination therapy  APR is now an unnecessary surgery for anal cancer, but still very common for distal rectal carcinoma

Levator Syndrome

 More commonly called

Proctalgia fugax

 It is episodic rectal pain caused by spasm of the levator ani muscles  A spasm is situated in the rectum approximately 10-15 cm above the anus  The pain or spasm is related to sitting for long periods of time  Pain is described as a sharp, knife-like, twisting inside the rectum

Levator Syndrome

 Physical examination is usually normal  Emotional factors, sexual activity, or fatigue can trigger an attack  Can also be triggered by an injury to coccyx or lower back  Structural deviations of the lumbro sacral area, sacro-iliac, coccyx, and supportive structures are also causes

OSTEOPATHIC TREATMENT

 A fracture or dislocation of the coccyx should be reduced by bi-manual manipulation  Levator ani tenderness will readily respond to OMT  Digital stretching of the ischiococcygeus tends to relax the entire structure, usually on the left lateral side

Beach Bum

Questions?