Transcript Document

Biomedical Engineering Key Content Survey - Results from Round One of a Delphi Study

David W. Gatchell and Robert A. Linsenmeier VaNTH ERC for Bioengineering Educational Technologies and Northwestern University Whitaker Foundation Biomedical Engineering Educational Summit March, 2005 Supported by NSF EEC 9876363

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Why conduct a BME key content survey? Motivation and potential benefits

 

Motivation

Establish an identity for undergraduate Biomedical Engineers

Improve communication between academic BME programs and industry

Academia – Inform industry of the knowledge, skills and training of BMEs

Industry – Inform academia of the knowledge, skills and training expected

Benefits

More industrial positions for BMEs

 

Each graduate does not have to explain curriculum Recognition that BME degree is ideal preparation for at least some industrial positions.

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Delphi study - Overview

In General:

An iterative process for collecting knowledge from, and disseminating

results to, a group of experts Four steps (repeat steps #2 and #3 to attempt to reach consensus)

1.

2.

Develop a set of questions on a topic. Experts give opinions on topics; suggest new ideas that were missed 3.

4.

Explore and evaluate inconsistencies uncovered in step 2 Disseminate findings, or revise questions and go back to 2 Key point is that experts remain anonymous

Our Study: A set of three surveys

Round 0:

Select concepts from VaNTH taxonomies; reviewed by domain

experts

Round 1:

Survey BME industrial representatives and faculty. Asked

 

participants to rate relevance of concepts important for

ALL undergrads in BME

, and make suggestions of concepts missed

Round 2

:

Refine and update list of concepts and resubmit to the above groups for further evaluation

Round 3:

Question proficiencies expected (e.g., using Bloom’s Taxonomy)

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  

Overview of the key content survey, round one

Utilized an online survey tool to query ~274 concepts:

 

Eleven bioengineering domains (including design) Physiology, cellular biology, molecular biology and genetics, biochemistry

Mathematical modeling, statistics, general engineering skills (e.g., computer programming)

Survey divided in two parts, each with half the domains:

Total number of participants, n = 136

 

Part one: Academia – 42, Industry – 25 Part two: Academia – 35, Industry – 23

Participants were asked to:

Provide demographic information

Employer, Job Title, Responsibilities, Years of Experience

 

Self-assess level of expertise in each domain (e.g., Biomechanics) Rate the importance/relevance of each concept to a BME core curriculum

Suggest concepts that had not been included

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Overview of the key content survey

Concepts rated on 5 point Likert Scale

 

1- very unimportant for all BMEs 5 – very important for all BMEs

Mean ratings across concepts similar for industry and academia

 

Academia (n=77) mean and SD rating: 3.71 ± 0.52

Industry (n=48) mean and SD rating: 3.75 ± 0.41

Domains Investigated:

Bioinformatics, bioinstrumentation, biomaterials, biomechanics, biooptics, biosignals and systems, medical imaging, thermodynamics, transport (fluid, heat, mass)

Cell biology, biochemistry, molecular biology and genetics, physiology

Statistics, general engineering

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Some concepts included as “Ringers” Expected to have low rating

Concept Statistical Physics (e.g., Bose-Einstein statistics; Fermi-Dirac statistics) Statistical Physics (e.g., Partition function; statistical representation of entropy; population of states) Comparative Genomics (e.g., ortholog and paralog genes; gene fusion events) Dynamical Instability and Chaos Unsteady state mass diffusion equation (e.g. Fick’s second law; production and consumption; boundary conditions; different geometries; multiple layers) Rating (Academia) 2.32

Rating (Industry) 2.58

2.82

2.50

2.59

3.42

2.58

2.94

3.11

3.29

All except unsteady state mass diffusion equation met expectations

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Some concepts included in more than one domain to check consistency of response

 

Two values shown are ratings when concepts are included in different domains Generally good agreement, but rating sometimes depended on context Concept Ratings (Academia) Ratings (Industry) Databases - Interfaces and Structures (e.g., MySQL, relational tables, simple queries, PERL, CGI, DBI) Signal Processing to Reduce Noise (e.g., signal-to-noise ratio; signal averaging) Properties of Systems (e.g., boundary, surroundings, universe) Electrochemical Potential, Nernst Potential, Fick's Law 2.29/2.66

4.24/3.83

3.88/3.97

4.09/4.23

3.22/3.68

4.17/4.14

3.63/3.88

3.54/4.00

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Results: Highest rated eng’g concepts – Academia Orange concepts are from statistics and general engineering Concept Hypothesis Testing (e.g., paired and un-paired t-tests; chi-square test) Rating 4.69

4.68

Principles of Statics (e.g., forces; moments; couples; torques; free body diagrams) Descriptive Statistics (e.g., mean, median, variance, std deviation) Circuit Elements (e.g., resistors, capacitors, sources, diodes, transistors, integrated circuits) DC and AC circuit analyses (e.g., Ohm's and Kirchoff's laws) Mathematical Descriptions of Physical Systems (e.g., functional relationships, logarithmic, exponential, power-law; ODEs; PDEs) Strength of Materials (e.g., stress, strain; models of material behavior) Pressure-Flow Relations in Tubes and Networks (e.g., flow rate = [change in pressure]/resistance; Poiseiulle relation; Starling resistor) Measurement concepts (e.g. accuracy, precision, … Regression analysis Forces and pressures in fluids (e.g. shear, normal, surface tension… 4.63

4.56

4.56

4.54

4.53

4.51

4.50

4.49

4.49

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Results: Highest rated eng’g concepts – Industry Orange concepts are from statistics and general engineering Rating Concept Descriptive Statistics (e.g., mean, median, variance, standard deviation) Measurement Concepts (e.g., accuracy, precision, sensitivity; error analysis - sources, propagation of error) Hypothesis Testing (e.g., paired and un-paired t-tests; chi-squared) Probability Distributions (e.g., normal, Poisson, binomial) 4.76

4.71

4.65

4.62

Strength of Materials (e.g., stress, strain; models of material behavior) 4.57

Fundamental Properties of Polymers, Metals and Ceramics Product Specification (e.g., requirements, design, reliability, evolution/tracking of the product) Principles of Statics (e.g., forces; moments; couples; torques; free body diagrams) Mechanical Properties of Biological Tissues (e.g., elastic; viscoelastic, hysteresis, creep, stress relaxation) Data Acquisition (e.g., sampling rates and analog-digital conversion; Nyquist criterion; aliasing) 4.50

4.45

4.43

4.43

4.39

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Results: lowest rated concepts

some from “Ringers”

Academia

Databases - Interfaces and Structures (e.g., MySQL, relational tables, simple queries, PERL, CGI, DBI) Statistical Physics (e.g., Bose-Einstein and Fermi-Dirac statistics) Artificial Intelligence (e.g., artificial neural networks, fuzzy logic) Analysis of Phylogenetic Trees, Molecular Evolution Comparative Genomics (e.g., ortholog and paralog genes; gene fusion events) Structural Prediction and Molecular Design

Industry

Statistical Physics (e.g., Partition function; statistical representation of entropy; population of states) Statistical Physics (e.g., Bose-Einstein; Fermi-Dirac statistics) Artificial Intelligence (e.g., artificial neural networks, fuzzy logic) Storage Instruments and their properties (e.g., tape, disk, memory) Comparative Genomics Root Locus Plots (e.g., definition, properties, sketching) 2.29

2.32

2.33 2.47

2.50

2.53

2.58

2.58

2.78

2.89

2.94

2.95

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Results: Industry - Academia agreement

Distribution of mean ratings of all concepts 5.00

4.00

3.00

Concept Ratings 2.00

2.00

2.50

3.00

3.50

Academia 4.00

4.50

5.00

  

Most concepts rated highly. Few ringers in survey.

All traditional domains had some highly rated concepts. Cutoff level for inclusion in recommended undergrad curriculum still to be determined on basis of further analysis and round two.

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Results: Industry – Academia Agreement Differences in means (A-I)

0.75

0.50

0.25

0.00

-0.25

-0.50

-0.75

-1.00

-1.25

0

Design

50 100 150 Concept # 200 250

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Results: Discrepancies in design concepts

Rankings - BME Design Concepts (A comparison of opinions from Academia and Industry) Decision Matrix Approaches to Initial Design Design for Manufacturing and Assembly Software for Design and Project Management (e.g., flowcharting; Gannt and PERT charts) Software and Process Design Considerations Risk Analysis/Hazard Analysis Computer-Aided Design Considerations Human Factors Issues/FDA

1.00

Industry Academia 2.00

3.00

4.00

Mean Ranking (all participants)

5.00

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Results: A comparison of general engineering concepts

Databas e s - Inte rface s and Structure s (e .g., MySQL, re lational table s , s imple que rie s , PERL, CGI, DB I) Artificial Inte llige nce (e .g., artificial ne ural ne tworks , fuzzy logic, e tc.) Familiarity with Multiple Computing Platforms (e .g., Windows , Macintos h, LINUX, UNIX) Scaling and Dime ns ional Analys is

Ringer Significant Deltas

Nume rical Diffe re ntiation and Inte gration Ge ne ralize d Ohm's Law (i.e ., driving force -flow-re s is tance conce pt) Compe te ncy with (at le as t) One Programming Environme nt (e .g., Matlab, Mathe matica, C, C++, FORTRAN) Es timation and Orde r of Magnitude Calculations Me as ure me nt Conce pts (e .g., accuracy, pre cis ion, s e ns itivity; e rror analys is - s ource s , propagation of e rror)

1.00

2.00

3.00

4.00

Mean Rating (all participants)

Industry Academia 5.00

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Results: Biology Domains

5.0

4.5

4.0

3.5

3.0

Biochemistry Cell Biology Molecular Biol.

Bioinformatics Unity slope 2.5

2.5

3.0

3.5

4.0

4.5

Rating of Concept - Academia 5.0

Good agreement on the whole

All biology areas important, but industry sees molecular biology as being more important than academia

Bioinformatics generally scored low, but industry feels that it is more important than academia does

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Results: Largest biology discrepancies

Concepts Flow of Genetic Information (i.e., DNA to RNA to Protein) Methods for Determining Macromolecular Structure (e.g., NMR...) DNA Microarrays Biological Networks (e.g., genetic networks...) Structural Prediction and Molecular Design (e.g., homology modeling and prediction of macromolecular structures and interactions) Academia Industry Academia - Industry 4.5

4.1

0.44

3.5

3.4

3.2

2.5

4.2

3.8

3.7

3.3

-0.70

-0.42

-0.46

-0.72

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Results: Physiology (82 concepts)

Very large span within domain

Generally good agreement

Cardiovascular, neural, cellular physiology concepts rated highly

Digestive, renal, parts of endocrine rated low 5.0

4.5

4.0

3.5

3.0

2.5

2.5

Physiology Unity slope 3.0

3.5

4.0

4.5

Rating of Concept - Academia 5.0

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Results: Largest physiology discrepancies between academia and industry

Concepts Cellular Anatomy (e.g...) Academia 4.56

Industry 4.14

Academia - Industry 0.41

Membrane Dynamics (e.g....) 4.44

3.95

0.49

Processes of the Kidney (e.g....) 4.26

3.85

0.41

Renal Filtration (e.g...) 4.03

3.60

0.43

Homeostasis of Volume and Osmolarity Water Balance and Urine Concentration 4.03

3.73

3.50

3.25

0.53

0.48

Platelets and Coagulation (e.g....) Sodium Balance and the Regulation of ECF Volume (e.g....) 3.21

3.76

3.75

3.15

-0.54

0.61

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Results: Should the following foundational courses be required?

Comparison of Responses - Industry and Academia Physics - Waves and Optics Physics - Electricity and Magnetism Physics - Mechanics Chemistry - Organic (Semester Two) Chemistry - Organic (Semester One) Chemistry - General Ordinary Differential Equations Linear Algebra Vector Calculus Calculus - Differential, Integral and Multivariate "NO" "UNSURE" "YES" Industry Academia

Agreement that second semester organic chemistry is not universally required; some uncertainty about one semester

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Universities represented in round one of the survey

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Arizona State University* Binghampton University Boston University* Columbia University Devry Institute of Tech Duke University* Florida International University IIT Johns Hopkins University* Marquette University* Milwaukee SOE* MIT NJIT NC State University* Northwestern University* RPI* RHIT Stanford University Syracuse University* 20.

21.

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SUNY – Stony Brook Tulane University* University of Akron* University of Cincinnati University of Illinois – UC* University of Iowa* University of Memphis University of Michigan University of Minnesota* University of Pittsburgh* University of Rochester* University of Texas – Austin* University of Toledo* Vanderbilt University* VCU* *ABET Accredited – 21 of 37 Accredited Programs Participated

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Companies and industrial expertise represented in round one of the survey

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Companies Represented

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Abbott Laboratories AstraZeneca Baxter Healthcare

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Boston Scientific Cardiodynamics Cleveland Medical Devices

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Datasciences, International Dentigenix, Inc.

Depuy, a Johnson and Johnson Co.

ESTECH Least Invasive Cardiac Surgery GE Healthcare Intel, Corp.

Materialise, Inc.

Medtronic, Inc. Tyco Healthcare Underwriter Laboratories

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Areas of Expertise

Biomaterials

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Biomechanics Bioinformatics Bioinstrumentation BioMEMS Biotransport Cellular Biomechanics Computational Modeling Control Systems Engineering Fluid Mechanics Medical Devices Medical Imaging Medical Optics Signal Processing

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Conclusions

More analysis is required to:

  

Investigate variation of opinions for individual topics Correlate ratings with expertise levels Eliminate contextual bias

Incorporate concepts omitted from first round

BUT, preliminary results have shown that:

  

“Consistency checks” validate data Generally good agreement between industry and academia Industry and academia disagree on a significant number of Design concepts

Industry highly values knowledge of statistics and probability

Core biology should include all domains assessed

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Conclusions

Remaining issues

Determine level of significance for deciding what concepts can be dropped from core curriculum

 

Determine significance of differences between industry and academia Launch second round – by summer

Full matrix of results by concept will be posted on www.vanth.org/curriculum

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