Psoriasis: The New Skin

Paris Fears Queens University of Charlotte SPAEP I Pittsburgh, PA

Table of Contents

Introduction

What is Psoriasis Background Epidemiology Genetics Physiology Quality of Life Treatments Conclusion Questions

Psoriasis

• • ‘Psora’ means to itch in Greek Gain an understanding of the disease, Psoriasis

Questions

Table of Contents Introduction

What is Psoriasis

Background Epidemiology Genetics Physiology Quality of Life Treatments Conclusion Questions References

Psoriasis

• Psoriasis, a chronic non infectious immune-mediated inflammatory skin condition that causes thick red and flaky patches of skin • • Natural Course 5 common types

Table of Contents Introduction

What is Psoriasis

Background Epidemiology Genetics Physiology Quality of Life Treatments Conclusion Questions References

Table of Contents Introduction

What is Psoriasis

Background Epidemiology Genetics Physiology Quality of Life Treatments Conclusion Questions References

Psoriasis

• • • Psoriasis, a chronic non infectious immune-mediated imflammatory skin condition that causes thick red and flaky patches of skin Plaque*-basic dry, itchy, red skin in common sites Natural Course scaly bumps Inverse*- occurs in excess skin folds and soft tissue 5 common type hands and feet Erythrodermic- aggressive plaque with pain and wide patches on entire body

Table of Contents Introduction What is Psoriasis

Background

Epidemiology Genetics Physiology Quality of Life Treatments Conclusion Questions References

Psoriasis

• • Mistoken for 150 years 1700’s to 1800’s Robert Willian and Jacob Plenck • 1841 Ferdinand von Hebra

Table of Contents Introduction What is Psoriasis Background

Epidemiology

Genetics Physiology Quality of Life Treatments Conclusion Questions References

Psoriasis

• • • • • 7.5-8.5 million 125 million 150,000 <400, >400 Everyone is at risk

Table of Contents Introduction What is Psoriasis Background Epidemiology

Genetics

Physiology Quality of Life Treatments Conclusion Questions References •40% increase in risk of contracting Psoriasis with "familial tendency" •Identical Twins incidence

Table of Contents Introduction What is Psoriasis Background Epidemiology Genetics

Physiology

Quality of Life Treatments Conclusion Questions References

Psoriasis

• • • • • • Psoriasis triggers Stress Little Sun Light Injury to skin Medication Immune system deficiencies

Table of Contents Introduction What is Psoriasis Background Epidemiology Genetics

Physiology

Quality of Life Treatments Conclusion Questions References

Psoriasis

Table of Contents Introduction What is Psoriasis Background Epidemiology Genetics

Physiology

Quality of Life Treatments Conclusion Questions References

Psoriasis

Table of Contents Introduction What is Psoriasis Background Epidemiology Genetics Physiology

Quality of Life

Treatments Conclusion Questions References

Psoriasis

• $1.6 billion to $4.3 billion dollars • 75% believe in negative impact • • • • Comorbidities HIV CVD Obesity and Alcohol Abuse

Table of Contents Introduction What is Psoriasis Background Epidemiology Genetics Physiology Quality of Life

Treatments

Conclusion Questions References

Psoriasis

• • • • • Controlled not Cured Topical treatments Home remedies Pills Alternative treatments

Table of Contents Introduction What is Psoriasis Background Epidemiology Genetics Physiology Quality of Life Treatments

Conclusion

Questions References

Summary

• • • • • Prevalent in all genders races, and ages 3-95 Effects about 125 million people worldwide Complex auto-immune inflammatory skin condition which includes, white scaly and raised red lesions Triggers include anything from bacterial and viral infection to stress The exact schematics to cure this disease are still a mystery

Table of Contents Introduction What is Psoriasis Background Epidemiology Genetics Physiology Quality of Life Treatments

Conclusion

Questions

References

QUESTIONS?

References

Table of Contents Introduction What is Psoriasis Background Epidemiology Genetics Physiology Quality of Life Treatments

Conclusion

Questions

References

• Babu, Hanish . "History of Psoriasis.” General Medicine (suite 101) (2008): n. pag. Web. 17 Jul 2011. • http://www.suite101.com/content/history-of-psoriasis-a85546 . Bhosle, Monali J, Amit Kulkarni, Steven R Feldman, and Rajesh Balkrishnan. "Quality of life in patients with psoriasis." Health and Quality of Life Outcomes 4.35 (2006): Web. 17 Jul • 2011. http://www.hqlo.com/content/4/1/35 >. Kurian, Anil, and Benjamin Barankin. "Current Effective Topical Therapies in the Management of Psoriasis." Skin Therapy Letter 16.1 (2011): 4-7. Web. 26 Jun • 2011.

http://www.skintherapyletter.com/2011/16.1/2.html

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Schön, Michael P, and W.-Henning Boehncke. "Psoriasis." N Engl J Med 352. (2005): n. pag. Web. 17 Jul 2011. http://www.nejm.org/doi/full/10.1056/NEJMra041320#t=article .