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rtery Catheterization Coronary Artery ypass Graft Pancreatic Resection Vagin rth After Cesarean Bilateral Artery atheterization Coronary Artery Bypass raft Pancreatic Resection Vaginal Birth fter Cesarean Bilateral Artery atheterization Coronary Artery Bypass raft Pancreatic Resection Vaginal Birth fter Cesarean Bilateral Artery atheterization Coronary Artery Bypass Introduction Why are IQIs so important? Pancreatic Discussion AIMS Resection CoronaryReferences Artery Methods Bypass Graft Vaginal Birth After Cesarean Results Congestive Heart Failure Bilateral Cardiac Catheterization Faculdade de Medicina da Universidade do Porto HEALTH INDICATORS Mortality Rates for Medical Conditions Prevention Quality Indicators Volume of procedures Inpatient Quality Indicators [1][2] Mortality Rates for Surgical Procedures Patient Safety Pediatric Quality Area-level Utilization Rates Indicators Indicators Hospital-level Procedure Utilization Rates [1] Nationwide inpatient sample and state databases. Health care cost and utilization project. Agency for healthcare research and quality, Rockville, MD; [2] Justin B. Dimick; H. Gilbert Welch; John D. Birkmeyer. Surgical Mortality as an Indicator of Hospital Quality: The Problem With Small Sample Size. JAMA, August 18, 2004; 292: 847 – 851. Faculdade de Medicina da Universidade do Porto IQIs offer a window into the medical care delivered in hospitals.[3] Why are IQIs so important? They can be used to flag potencial quality problems and success stories, which can be further investigated.[3] Through them, we can identify differences between hospitals, regions or communities.[3] They provide a comprehensive picture of the level and variation of quality within four components of health care quality: effectiveness, safety, timeliness and patient centeredness.[3] [3] Nationwide inpatient sample and state databases. Health care cost and utilization project. Agency for healthcare research and quality, Rockville, MD Faculdade de Medicina da Universidade do Porto Evaluation of hospital´s quality of care : How can we select good/valid inpatient quality indicators? 1 Aims Analyze several IQI’s selection methods used in studies; Select 5 IQIs and explore their advantages and limitations; 3 2 Compare IQIs and conclude on how well do they reflect hospital care quality; Conclude about the utilization of IQIs on the evaluation of the quality of healthcare services. 4 Faculdade de Medicina da Universidade do Porto IQIs’ 1 Faculdade de Medicina da Universidade do Porto Analysis of a series of studies Combination of results simultaneously adequate and representative Answer the central question Faculdade de Medicina da Universidade do Porto 1 “How are IQIs selected and how well do they reflect Formulation of the central question; a hospital’s quality? – Five IQIs’ example”; 2 Definition of the criteria for selection of the articles (inclusion/exclusion); 3 Bibliographic data base (MEDLINE and ISI Web of Definition of the research strategy; Knowledge); 4 Procedures frequently used in medical practice or Selection of 5 IQIs to analyze. common health problems . Faculdade de Medicina da Universidade do Porto QUERIES APPLIED 5 Statistics on theResearch disease’sphase prevalence/utilization of procedure; Definition of the IQI; [Bilateral Cardiac Catheterization] or [Bilateral Cardiac Catheterization AND Advantages and disadvantages its utilization. Inpatient Quality Indicator, Healthof Care] Data collection 6 Evaluate the quality of the five IQIs on the appraisement of a hospital’s [Coronary Artery Bypass Graft] or [Coronary Artery Bypassservices; Graft AND Inpatient Quality Indicator , Health Care] or [CABG] Data process and analysis [Pancreatic Resection] or [Pancreatic Resection AND Inpatient Quality Indicator Answer the central question: conclude on , Health Care] how well do IQIs reflect a hospital’s quality. 7 [Congestive Heart Failure] or [Congestive Heart Failure AND Inpatient Quality Indicator , Health Care] or [CHF AND Inpatient Quality Indicator , Health Care] [Vaginal Birth after Cesarean] or [Vaginal Birth after Cesarean AND Inpatient Quality Indicator , Health Care] or [VBAC] Faculdade de Medicina da Universidade do Porto 1 English LANGUAGE Criteria for the selection of articles TIME LIMITATION Articles dated between 2004 and 2009; 2 reviewers TITLE AND ABSTRACT EXCLUSION Focus on both procedure/health problem and quality indicator Faculdade de Medicina da Universidade do Porto 2 2 reviewers Inpatient quality Indicators Inclusion criteria Criteria for the selection of articles Advantages/disadvantages concerning the procedure/medical problem Possible generalization of the results Other types of quality indicators Exclusion criteria Lack of data associated to the IQI Over specific reviews Faculdade de Medicina da Universidade do Porto 2 Faculdade de Medicina da Universidade do Porto PR VBAC CABG BCC CHF 11 articles 9 articles 8 articles 4 articles 17 articles 7 6 6 2 9 4 3 2 Included articles 2 8 Excluded articles Faculdade de Medicina da Universidade do Porto [4] GIRALDES MDO R Efficiency versus quality in the NHS, in Portugal: methodologies for evaluation Acta Med Port. 2008 Sep-Oct21(5):397-410. E.pub 2009 Jan 16. VAGINAL BIRTH PANCREATIC RESECTION CORONARY ARTERY BYPASS GRAFT AFTER CESAREAN CONGESTIVE HEART FAILURE BILATERAL CARDIAC CATHETERIZATION Faculdade de Medicina da Universidade do Porto Set limits regarding the number of PRP procedures, to compare different hospitals; Rare procedure that requires technical PR volumes are divided into: high, low or medium. proficiency; Providers with higher volumes have lower mortality rates for the procedure; Errors management may lead to Suggests thatin thiscirurgical providers have some characteristics, either structurally or with regard to procedure thatcomplications; clinical significally influences mortality[5]. VOLUME INDICATOR Indicates the raw volume compared to annual threshold (100 and 200 procedures); Relationship between hospital volume and mortality is unclear[6]; Better processes of care and the increasing of hospital Hospitals performing highrepresents volume of procedures procedures may reduce mortalityawhich with an increased complexity may have better better quality of care. outcomes. MORTALITY INDICATOR Indicates the number of deaths per 100 pancreatic resection procedures; High mortality may be associated with poorer quality of care. [5] LIEBERMAN, MICHAEL; KILBURN, H; LINDSAY M.A.; MICHAEL, PhD.; BRENNAN Murray F.; M.D; Relation of Perioperative Deaths to Hospital Volume Among Patients Undergoing Pancreatic Resection for Malignancy; Ann Surg. 1995 Nov;222(5):638-45 [6] DIMICK JB; COWAN JAJr; COLLETI LM; Upchurch GR Jr; Hospital Teaching Status and Outcomes of Complex Surgical Procedures in the United States; Arch Surg. 2008 Jan;206(1):13-6. Epub 2007 Oct 18. Faculdade de Medicina da Universidade do Porto Introduction of risk adjustment for clinical factors (prevent confunding bias); Some factors (finantial conditions of the hospitals and patients characteristics) may cause illusory results [7]; MORTALITY INDICATOR VOLUME INDICATOR Proxy measure for quality – should be used with other indicators. Not performed frequently enough to judge hospital quality – poor precision [8]. [7] Marques JR ET; Maciel Filho R; August PN; Overcoming health inequity: potential benefits of a patient-centered open-source public health infostructure; Cad saude publica. 2008 Mar;24(3):547-57. [8] DIMICK Justin B; WELCH H Gilbert; BIKMEYER John D; Surgical Mortality as an Indicator of hospital quality the problem with small sample size; JAMA. 2004; 292(7):847-851. Faculdade de Medicina da Universidade do Porto Coronary artery bypass graft is a form of surgery that create new routesa good measure of IndicatesIt raw volumeto setbypass is necessary limits regarding thecanTo be considered Indicates thequality, number Indicates the number aroundArea-level narrowed and blocked number of CABG procedures to compare thecoronary procedure must have both a utilization compared to annual of CABGs per 100,000 of per 100 Volume Indicator arteries, allowing increased blood flow the Mortality different hospitals; relatively hightomortality ratedeaths and beIndicator threshold (100 and 200 CABG volume is divided indicator delivery and nutrients to the heart frequently; population CABG procedures into: high, lowoxygen or medium; performed procedures) muscles. The limits do not correspond to a certain amount but are derived from an evaluation of the association between hospitals’ CABG volume and in-hospital mortality. This rate depends on certain factors, including the finantial conditions of the hospital – the mortality rate is higher in hospitals less developed [9]. [9] Dimick J, Welch H, Birkmeyer. Surgical Mortality as an indicator of Hospital Quality: The Problem With Small Sample Size. JAMA. 2004 Faculdade de Medicina da Universidade do Porto The association between CABG procedures and mortality rates is not constant; Patients at high-volume CABG hospitals are at a lower mortality risk than patients at lower volume hospitals [10][11]; This association been declining over time because ofIndicator the improvement of Volumehas Indicator Mortality cirurgical training and technical advances[12]; Other studies: the correlation between the number of surgeries and mortality is weak[13] and depends on the age of the studies’ participants[14]. [10] Rathore S, Epstein A, et al. Hospital Coronary Artery Bypass Surgery Volume and Patient Mortality, 1998-2000. Annals of Surgery. January 2004 [11] Shahian D, O’Brien S, Normand S, et al. Association of hospital coronary artery bypass volume with processes of care, mortality, morbidity, and the Society of Thoracic Surgeons composite quality score. The Journal of Thoracic and Cardiovascular Surgery. February 2010 [12] Volume and outcome of CABG surgery: are more and less the same? [13] Mesquita ET, Ribeiro A, Araújo MP, Campos LA, Fernandes MA, Colafranceschi AS, Silveira CG, Nunes E, Rocha AS. Indicators of healthcare quality in isolated coronary artery bypass graft surgery performed at a tertiary cardiology center. Arq Bras Cardiol. May 2008 [14] Adogwa O, Costich JF, Hill R, Slavova S. Does higher surgical volume predict better patient outcomes? J Ky Med Assoc.. January 2009 Faculdade de Medicina da Universidade do Porto Provider-level indicator that Represents the relative risks and estimates vaginal births per 100 benefits of a trial of labor in discharges (fix volume of labors patients with previous cesarean in a hospital) with a diagnosis of delivery previous cesarean delivery Observed differences represent true differences in provider Disadvatanges performance rather than random variation reduce medical costs substantially;[15] Higheranemia rates represent better long term risks of a cesarean section include uterine rupture, maternal infection, Underused and procedure quality perinatal death and others);[15] unsuccessful trial of labor (TOL), in which a woman undergoes a repeated cesarean delivery instead of a vaginal delivery, has a higher rate of complications compared to a VBAC and elective repeat cesarean delivery (ERCD); Advantages the overall benefits of TOL are directly related to having a VBAC as these women typically have the lowest morbidity; maternal mortality is low: 3.8 per 100 000 women who undergo a TOL die versus 13.4 per 100 000 women who undergo a ECRD die; [15] McGrath P, Phillips E; Bioethics and birth: insights on risk decision-making for an elective caesarean after a prior caesarean delivery; Monash Bioeth Rev. 2009 Sep;28(3):22.1-19 Faculdade de Medicina da Universidade do Porto the delivery category with fewest complications is repeat cesarean – 72% had no complications[16]; IQI measure is associated to a personal choice (whether to take or not risks on a surgery); VBAC posed a higher risk than an elective cesarean (EC)[16]; dependent on medical advisement[17]; facts tend to change a mother’s choice[17]; [16] McGrath P, Phillips E; Bioethics and birth: insights on risk decision-making for an elective caesarean after a prior caesarean delivery; Monash Bioeth Rev. 2009 Sep;28(3):22.1-19 [17] Gregory KD, Korst LM, Fridman M, Shihady I, Broussard P, Fink A, Burnes Bolton L.; Vaginal birth after cesarean: clinical risk factors associated with adverse outcome; Am J Obstet Gynecol. 2008 Apr;198(4):452.e1-10; discussion 452.e10-2. Faculdade de Medicina da Universidade do Porto Progressive cronic disease and a relatively common admission with substantial short-term mortality Mortality rate from CHF has progressively declined over time[19] mainly because it can be significally reduced with appropriate terapy [20] CHF is an important public health problem, in part because survival following diagnosis is poor[18] As better processes of care may reduce short-term mortality, CHF mortality rates could be used to indicate the quality of health care facilities CHF mortality rate is a mortality indicator for inpatient conditions and measures the number of deaths per 100 discharges with principal diagnosis code of CHF CHF mortality has been widely used as a quality indicator: it is precise [21] and captures an aspect of quality that is regarded as important [18] Goff, DC, Jr., Pandey DK, Chan FA, et al. Congestive heart failure in the United States: is there more than meets the I(CD code)? The Corpus Christi Heart Project. Arch Intern Med 2000 [19] Ni H, Hershburger FE. Was the decreasing trend in hospital mortality from heart failure attributable to improved hospital care? The Oregon experience, 1991-1995. Am J Manage care 1999 [20] Maclntyre K, Capewell IS, Stewart S, et al. Evidence of improving prognosis in heart failure: trends in case fatality in 66547 patients hospitalized between 1986 and 1995. Circulation 2000 [21] Nationwide Inpatient Sample and State Databases.Healthcare Cost and Utilization Project. Agency for Healthcare Research and Quality, Rockville, MD. Faculdade de Medicina da Universidade do Porto Bias caused by the admitting decision – failing to admit the sickest patients Mortality rate may depend Mortality is greatly influenced could a hospital’s theimprove type of that healthcare byon other factors can lead survival rate [24] facility to bias. Specialized hospitals have modestly lower risk and rate of short In-hospital mortality Differences in mortality rates term mortality than general hospitals measureshospitals may between can be [23] encourage early Patients at post-operative teaching hospitals have attributed to unobserved better survival rates than those discharge shift patientsand andthereby hospital among other hospitals [24] deaths to skilled [22]. nursing characteristics facilities or outpatient settings [25] GENERAL [22] Werner, RM, Bradlow, ET. Relationship between Medicare’s Hospital compare performance measures and mortality rates. JAMA 2006 [23] Nallamothu, BK, Wang, Y, Cram, P, et al. Acute myocardial infarction and congestive heart failure outcomes at specialty cardiac hospitals. Circulation 2007 [24] Poses, RM, McClish, DK, Smith, WR, et al. Results of report cards for patients with congestive heart failure depend on the method used to adjust for severity. Ann Intern Med 2000 [25] Rosenthal, GE, Baker, DW, Noris, DG, et al. Relationships between in-hospital and 30-day standardized hospital mortality: implications for profiling hospitals. Health Services Research 2000 Faculdade de Medicina da Universidade do Porto PARTICULAR [26] Rosenthal, GE, Baker, DW, Noris, DG, et al. Relationships between in-hospital and 30-day standardized hospital mortality: implications for profiling hospitals. Health Services Research 2000 Ascertaining deaths that CHF is aafter condition that Hospitals in regions withisa occur discharge increases exponentially larger elderly population will tedious and expensive ifwith done aging. As the size of the have higher primary mortalitydata rate, through elderly population increases, without being directly collection and may raise the substancial morbidity and associated with quality concerns about risks toof the mortality attributable to CHF care. patient confidentiality [26]. will continue to increase [26]. Faculdade de Medicina da Universidade do Porto BCC is considered appropriate in the presence of certain clinical indications Less influenced by discharge variation Signal ratio very high at 96,2% - observed Hospital-level differences in provider Procedure Utilization performance likely Rates represent true differences, rather than random variations Based onPrecise empirical evidence – very precise [28] [28]Nationwide inpatient sample and state databases. Health care cost and utilization project. Agency for healthcare research and quality, Rockville, MD Cardiac catheterization is a diagnostic test that can show if blood vessels to the heart are narrowed or blocked; A liquid dye is injected into the arteries of the heart through a catheter, a long narrow tube that is fed through artery, usually in Generalanprocedure the thigh, to arteries in the heart[27] [27]http://www.dshs.state.tx.us/THCIC/publications/hospitals/IQIReport2004/Chart25.pdf The validity rests on the assumption that the prevalence of this clinical indication is low and relatively uniformed Substantial variation in the use of BCC at two large community hospitals was found, even after adjusting for clinical indications [29] Other source of potential [29] Malone ML,bias: Bajwa large TK, Battiola RJ, et al.of number Variation among cardiologists in the utilization catheterizations of right heart catheterization at time of performed on an coronary angiography [see comments]. Cathet Cardiovasc Diagn 1996;37(2):125-30. outpatient basis Faculdade de Medicina da Universidade do Porto 3 Faculdade de Medicina da Universidade do Porto Higher procedure volume has lower mortality rates as it depends on technical profeciency and pacient’s characteristics (low precision); Must have a relatively high mortality rate and be performed frequently. The association between CABG procedures and mortality rate depends on the volume of procedure of each hospital. It also depends on several factors as financial conditions. The analysis must not be done separating the volume from the mortality rate (imprecise predictor of quality); IQI combination must be done to allow a precise evaluation of a hospital’s quality High rates represent better quality. Factors related with the mother’s health (for instance, obesity and uterine conditions) can influence the success rates (good measure). Better processes of treatment can contribute for reducing short term mortality (that depends on the characteristic of each hospital and patient). It is a precise indicator and serves as base for comparative studies of care’s quality; It is considered appropriate in the presence of certain clinical factors and contraindicated in most patients so lower rates represent better quality. Significance of the result isn’t affected by external factors (high precision rates); Faculdade de Medicina da Universidade do Porto The collection of inpatient quality indicators represents a part of the actual state of care’s quality using literature data. However, this indicators must be used cautiously because the research done has limitation. Language Articles which seemed to have good information were not available free of charge and were not able to obtain even after contacting the corresponding author Availability Contradiction Led to the inclusion of articles since 1990 and might have resulted in outdated information Adaptation problems Paucity of information (the volume of procedures may bethe lower, theso incidence of to The data found concerns mostly USA it is hard diseases may be different and the technology available is not the transpose the conclusions to the reality of Portugal same) Faculdade de Medicina da Universidade do Porto Although this information represents a rich data source that can provide valiable information it should not be used as a definitive source. This review allowed to reveal real quality problems for which quality improvement programs can be initiated It also showed that additional clinical information is required to understand the quality issues. These indicators provide a starting point for further investigations that might explore severity of illness differences Need for establishing patterned For example, hospitals with criteria thathigher allowthan classification of a average mortality hospital's volume procedures (high,or rates forofspecific procedures conditions probe the medium or low should volume) underlying reasons: • [1] Nationwide inpatient sample and state databases. Health care cost and utilization project. Agency for healthcare research and quality, Rockville, MD http://www.ahrq.gov/data/hcup • [2] Justin B. Dimick; H. Gilbert Welch; John D. Birkmeyer; Surgical Mortality as an Indicator of Hospital Quality: The Problem With Small Sample Size; JAMA, August 18, 2004; 292: 847 – 851 • [3] Nationwide inpatient sample and state databases. Health care cost and utilization project. Agency for healthcare research and quality, Rockville, MD (http://www.ahrq.gov/data/hcup) • [4] GIRALDES MDO R Efficiency versus quality in the NHS, in Portugal: methodologies for evaluation; Acta Med Port. 2008 SepOct21(5):397-410. E.pub 2009 Jan 16. • [5] LIEBERMAN, MICHAEL; KILBURN, H; LINDSAY M.A.; MICHAEL, PhD.; BRENNAN Murray F.; M.D; Relation of Perioperative Deaths to Hospital Volume Among Patients Undergoing Pancreatic Resection for Malignancy; Ann Surg. 1995 Nov;222(5):638-45 • [6] DIMICK JB; COWAN JAJr; COLLETI LM; Upchurch GR Jr; Hospital Teaching Status and Outcomes of Complex Surgical Procedures in the United States; Arch Surg. 2008 Jan;206(1):13-6. Epub 2007 Oct 18. • [7] Marques JR ET; Maciel Filho R; August PN; Overcoming health inequity: potential benefits of a patient-centered open-source public health infostructure; Cad saude publica. 2008 Mar;24(3):547-57. • [8] DIMICK Justin B; WELCH H Gilbert; BIKMEYER John D; Surgical Mortality as an Indicator of hospital quality the problem with small sample size; JAMA. 2004; 292(7):847-851. • [9] Dimick J, Welch H, Birkmeyer. Surgical Mortality as an indicator of Hospital Quality: The Problem With Small Sample Size. JAMA. 2004 • [10] Rathore S, Epstein A, et al. Hospital Coronary Artery Bypass Surgery Volume and Patient Mortality, 1998-2000. Annals of Surgery. January 2004 • [11] Shahian D, O’Brien S, Normand S, et al. Association of hospital coronary artery bypass volume with processes of care, mortality, morbidity, and the Society of Thoracic Surgeons composite quality score. The Journal of Thoracic and Cardiovascular Surgery. February 2010 • [12] Volume and outcome of CABG surgery: are more and less the same? • [13] Mesquita ET, Ribeiro A, Araújo MP, Campos LA, Fernandes MA, Colafranceschi AS, Silveira CG, Nunes E, Rocha AS. Indicators of healthcare quality in isolated coronary artery bypass graft surgery performed at a tertiary cardiology center. Arq Bras Cardiol. May 2008 • [14] Adogwa O, Costich JF, Hill R, Slavova S. Does higher surgical volume predict better patient outcomes? J Ky Med Assoc.. January 2009 • [15] McGrath P, Phillips E; Bioethics and birth: insights on risk decision-making for an elective caesarean after a prior caesarean delivery; Monash Bioeth Rev. 2009 Sep;28(3):22.1-19 • [16] McGrath P, Phillips E; Bioethics and birth: insights on risk decision-making for an elective caesarean after a prior caesarean delivery; Monash Bioeth Rev. 2009 Sep;28(3):22.1-19 • [17] Gregory KD, Korst LM, Fridman M, Shihady I, Broussard P, Fink A, Burnes Bolton L.; Vaginal birth after cesarean: clinical risk factors associated with adverse outcome; Am J Obstet Gynecol. 2008 Apr;198(4):452.e1-10; discussion 452.e10-2. • [18] Goff, DC, Jr., Pandey DK, Chan FA, et al. Congestive heart failure in the United States: is there more than meets the I(CD code)? The Corpus Christi Heart Project. Arch Intern Med 2000 • [19] Ni H, Hershburger FE. Was the decreasing trend in hospital mortality from heart failure attributable to improved hospital care? The Oregon experience, 1991-1995. Am J Manage care 1999 • [20] Maclntyre K, Capewell IS, Stewart S, et al. Evidence of improving prognosis in heart failure: trends in case fatality in 66547 patients hospitalized between 1986 and 1995. Circulation 2000 • [21] Nationwide Inpatient Sample and State Databases.Healthcare Cost and Utilization Project. Agency for Healthcare Research and Quality, Rockville, MD. (http://www.ahrq.gov/data/hcup) • [22] Werner, RM, Bradlow, ET. Relationship between Medicare’s Hospital compare performance measures and mortality rates. JAMA 2006 • [23] Nallamothu, BK, Wang, Y, Cram, P, et al. Acute myocardial infarction and congestive heart failure outcomes at specialty cardiac hospitals. Circulation 2007 • [24] Poses, RM, McClish, DK, Smith, WR, et al. Results of report cards for patients with congestive heart failure depend on the method used to adjust for severity. Ann Intern Med 2000 • [25] Rosenthal, GE, Baker, DW, Noris, DG, et al. Relationships between in-hospital and 30-day standardized hospital mortality: implications for profiling hospitals. Health Services Research 2000 • [26] Rosenthal, GE, Baker, DW, Noris, DG, et al. Relationships between in-hospital and 30-day standardized hospital mortality: implications for profiling hospitals. Health Services Research 2000 • [27]http://www.dshs.state.tx.us/THCIC/publications/hospitals/IQIReport2004/Chart25.pdf • [28]Nationwide inpatient sample and state databases. Health care cost and utilization project. Agency for healthcare research and quality, Rockville, MD (http://www.ahrq.gov/data/hcup) • [29] Malone ML, Bajwa TK, Battiola RJ, et al. Variation among cardiologists in the utilization of right heart catheterization at time of coronary angiography [see comments]. Cathet Cardiovasc Diagn 1996;37(2):125-30. THE END