Transcript Smart Cervical Dilator - Biomedical Engineering

DilaPro
Benjamin Lee
Anne Kwei
Matthew Lee
Grace Shih
Dr. Clark Hung, Faculty Advisor
October 20, 2009
Design Problem
• Many types of cervical dilation procedures
– Various dilation requirements
• Differing physiologies between patients
– No one typical cervix
• Current devices have limited scope and
functionality
Procedures and Complications
• 2.5 million procedures per year in the US
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Diagnostic sampling of uterine tissue
Treatment of cervical stenosis
Planned and unplanned pregnancy termination
Induction of labor
• Complications due to uncontrolled dilation
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Tissue damage
Insufficient dilation
Inadvertent induction of labor
Excessive patient discomfort
Differing Physiologies
• Variable cervix composition
– Not pregnant
– Currently pregnant
• Gestational age
• Previous deliveries
Myers, K. M.; Paskaleva, A. P.; House, M.; Socrate, S., Mechanical and biochemical properties of human cervical tissue. Acta Biomater 2008, 4 (1), 104-16.
Current Devices
• Mechanical Dilators
– Dilation to small diameters
• Osmotic Dilators
– Intermediate to large diameters
– Laminaria (natural) and Dilapan (synthetic)
• Pharmacologic Agents
– Misoprostol (prostaglandin)
• Labor Inducer
– Foley catheter
Current Device Limitations
Design Constraints and Specifications
Mechanical
Osmotic
•Withstand cervical pressure for duration of procedure
YES
YES
•Must not affect patient well-being
YES
YES
•Nonabrasive and nonreactive with cervical wall
YES
YES
•Must fit into the cervix
YES
YES
•Dilate fully
NO
YES
•Portable, lightweight
NO
YES
•Sense and adjust to cervical and uterine pressures
NO
NO
•Accurately and consistently apply radial pressures
NO
NO
•Adaptable to all procedures requiring cervical dilation
NO
NO
•Adaptable to unique, individual cervix physiologies
NO
NO
Safety
Functionality
Accuracy
Adaptability
Design Brief
• “Smart” Cervical Dilator
– Expandable device in the cervix
– External processing unit
– Feedback system that allows the processing unit
to dynamically control and track progress of
dilation
– Portable and comfortable for patient
Related Products
• Angioplasty balloons
– Expandable
– Biostable
– Ease in design, construction, and application
• Stents
– Structurally strong
– Chemically inert
– Used to hold open constricted tubes
• Inflatable Car Jack
– Withstands high external pressures
DilaPro Balloon
• Lightweight
• Balloon is easily adjustable
DilaPro Stent
• Utilizes mechanical strength of a stent
• Stent can lock in place
DilaPro Osmotic Dilator
• Utilizes osmotic forces to assist in dilation
• Avoids risks of pressurized air
Thank You!
Dr. Clark Hung
Professor of Biomedical Engineering
Dr. Elizabeth Hillman
Assistant Professor of Biomedical Engineering
Dr. Rachel Masch
Associate Director of Family Planning, Beth Israel Hospital
Dr. Rujin Ju
Beth Israel Hospital
Keith Yeager
Senior Staff Associate, Laboratory Manager
Lauren Grosberg
Graduate Student in Biomedical Engineering