Transcript Funding Mechanism

Diabetic Retinopathy Clinical
Research Network (DRCR.net)
Dedicated to multicenter clinical research of diabetic
retinopathy, macular edema and associated disorders.
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DRCR Network Overview
 Objective:
• Develop and operate a collaborative
network to facilitate multicenter clinical
research on diabetic retinopathy, diabetic
macular edema and associated
conditions.
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There have been 2716 subjects recruited for
DRCR.net studies since the networks inception
 437 investigators have been certified for at least
one protocol.
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DRCR Network Overview
 Funding:
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National Eye Institute (NEI)
• Sponsored cooperative agreement initiated
September 2002; initially through
December 31, 2008
• Competitive renewal request every 5 years
• Renewed from 2009-2013
Industry collaborations
Foundations (e.g. JDRF)
Unrestricted gifts
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Priority Initiatives
 Involvement of community-based
practices, as well as academic centers
 Collaborate with industry to facilitate
investigations and pursue opportunities
otherwise not possible and to do so in a
manner consistent with the Network’s
dedication to academic integrity and optimal
clinical trial performance
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Network Organization
 Coordinating Center
• Roy Beck, M.D., Ph.D. (Executive Director)
• Adam Glassman, M.S. (Assistant Director)
 Network Chair
• Neil M. Bressler, M.D. (current)
• Lloyd Paul Aiello, M.D., Ph.D. (inaugural & past
chair)
 Network Vice-Chairs
• Susan Bressler, M.D.
• Scott Friedman, M.D.
• Ingrid Scott, M.D.
 NEI
• Donald F. Everett, M.A.
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Network Enrollment as of 9-31-09
Protocol
# of
Subjects
A: A Pilot Study of Laser Photocoagulation for DME
319
B: A Randomized Trial Comparing Intravitreal Triamcinolone
Acetonide and Laser Photocoagulation for DME
693
C: Temporal Variation in Optical Coherence Tomography
Measurements of Retinal Thickening in DME
107
D: Evaluation of Vitrectomy for DME
241
E: A Pilot Study of Peribulbar Triamcinolone Acetonide for
DME
113
F: An Observational Study of the Development of DME
Following Scatter Laser Photocoagulation
155
G: Subclinical Diabetic Macular Edema Study
613
H: Phase 2 Randomized Trial of Bevacizumab for DME
121
Network Enrollment as of 9-31-09
Protocol
# of Subjects
I: Intravitreal Ranibizumab or Triamcinolone Acetonide in Combination with
Laser Photocoagulation for DME
691
J: Intravitreal Ranibizumab or Triamcinolone Acetonide as Adjunctive
Treatment to Panretinal Photocoagulation for Proliferative Diabetic
Retinopathy
333
K: The Course of Response to Focal Photocoagulation for DME
128
Currently Recruiting
L:Evaluation of Visual Acuity Measurements in Eyes with
Diabetic Macular Edema
209
O: Comparison of Time Domain OCT and Spectral Domain OCT Retinal
Thickness Measurement in Diabetic Macular Edema
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P: Pilot study in individuals with center-involved diabetic macular edema
undergoing cataract surgery.
Q: An observational study in individuals with diabetic retinopathy without
center-involved diabetic macular edema undergoing cataract surgery.
DRCR Network Study Subject Total
3,747
For information about
1. Becoming a DRCR network investigator
2. Proposing collaborative clinical trial
opportunities
3. A complete listing of DRCR publications
4. Or for other information
E-mail [email protected]
Or visit or our website www.drcr.net
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