Transcript Optical Quality of the Synchrony IOL

The Synchrony IOL is not currently FDA-approved
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OPTICAL QUALITY OF DUALOPTIC ACCOMMODATING
INTRAOCULAR LENS
Andrea Galvis, MD 1,3 a
Ivan Ossma, MD MPH MSc 1,2, a
Sanjeev Kasthurirangan, PhD 4, b
1 Fundacion Valle del Lili, Cali-Colombia
2 Universidad Industrial de Santander, Bucaramanga-Colombia
3 Universidad Autonoma de Bucaramanga, Bucaramanga-
Colombia
4 Abbott Medical Optics Inc, Irvine, USA
Financial Disclosure
a Consultant Abbott Medical Optics
b Scientist at Abbott Medical Optics Inc.
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Synchrony Design
Anterior Optic 32
Diopters
Posterior Optic
Divergent (negative)
Study Purpose
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Compare Optical Quality Pseudophakic Eyes
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Monofocal IOL
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Synchrony Dual Optic Accommodating IOL
Parameters
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Objective iTrace aberrometry
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Custom Matlab Software to calculate MTF
Subjective Contrast Sensitivity Testing
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Optec 6500
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Study Population
iTrace aberrometry
 Cycloplegia
 3 mm zone
 Matlab Software to calculate MTF
 Monofocal IOL : 15 subjects (30 eyes)
 Synchrony IOL : 16 subjects (32 eyes)
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iTrace - Matlab conversion
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Results
Objective Measurements
3 mm pupil
Difference 0.01 um
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Best-focus MTF
3 mm pupil
Differences are less than 10%
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Mesopic Contrast Sensitivity
p=0.61 Wilcoxon Rank Sum Test
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Discussion
 Dual Optic Design DOES NOT affect optical or retinal image
quality of the eye
 Objective evidence (iTrace, MTF)
 Subjective evidence (CSF)
 Contrast sensitivity of Synchrony is equivalent to that of
monofocal IOLs
Discussion
 Effect of the slight spherical aberration on
Synchrony would only yield 0.42 D of increased
depth of focus
 Calculations based on Rocha’s work *
 The improved near vision of Synchrony patients
MOST LIKELY due to true accommodation
* Rocha KM. Using Adaptive Optics Simultion to Explore the Effect of Higher Order Aberrations on Depth of
Focus for the Correction of Presbyopia. Wavefront Congress 2008
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Conclusion
 Quality of Vision of Synchrony IOL similar to
standard monofocal IOLs
 Measured Subjectively
 Measured Objectively
 Improved Near Vision with Synchrony
 Not related to increased depth of focus