Transcript ICA Introduction - ICA TriNova, LLC Home Page

ICA TriNova, LLC
ICA TriNova, LLC
• A marketing and development company
seeking to commercialize new technologies
• Founded in 1999 and headquartered in
Atlanta GA
• Privately held
• Specializing in solid phase chemical release
systems for ClO2, CO2, H2O2, etc
ICA TriNova, LLC
Impregnate Technology Platform
carrier media
Chemistry B
Chemistry A
Mixing
Activation
Desired absorption
or oxidation
Controlled
reaction / release
ICA TriNova, LLC
Chlorine Dioxide
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Formula - ClO2
CASRN 10049-04-4
Mol. Wt - 65.5
Highly Soluble in Water
(>Chlorine)
• Stable Free Radical
•
•
•
•
•
•
•
Strong oxidizer and biocide
Works over broad pH range, 2 - 10
Does not react with ammonia
Effective against biofilms
Does not substitute onto organics
Highly soluble in water
Cannot be Shipped - Made on site
ICA TriNova, LLC
ClO2 Chemistry
• Sodium Chlorite - NaClO2
- Acids +/or Reducing Species
- Chlorine
- Fast Kinetics
- HCl, H2SO4, Citric, Acetic, etc.
- Example
4ClO2- + 4H+ ---> 2ClO2 + ClO3- + Cl- + 2H+ + H2O
ICA TriNova, LLC
Traditional ClO2 Technologies
ICA TriNova, LLC
ICA ClO2 Technology
• Z-Series Solids
- mg- kg/day
- Controlled Activation
- Efficient Chemistry
- Easy to use
- Safe
- Solutions, Gas, Powders
ICA TriNova, LLC
Effect of Activator -Z : NaClO -Z Ratio
2
on ClO generation at 79F
2
Micromols ClO2 per gm Z-material
250
200
150
100
50
S am pl e
S am pl e
S am pl e
S am pl e
0
-50
-50
0
50
100
Time, hr
1
2
3
4
150
Ratio
0.00
0.10
0.20
1.00
200
ICA TriNova, LLC
ClO2 Solution Delivery System
ICA TriNova, LLC
ClO2 Gas Delivery System
ICA TriNova, LLC
Data Collection Programs
Program
Study Focus
Produce
Food Safety & Shelf Life
Water
Disinfection & Oxidation
Poultry & Meat
Food Safety & Animal Health
Horticulture
Shelf Life & Oxidation
Agriculture
Food Safety & Yields
Indoor Air Quality
Odor Control & Mold
Pest Management
Mosquitoes, Ticks, Fleas
Bio/Chem Threat
Anthrax, Virus
** Government, Universities, Customers, and Partners
ICA TriNova, LLC
ClO2 for Drinking Water
Advantages*
Historical Disadvantages*
Lowers halogenated DPDs
Specialized Equipment
Improved taste/odor
Chemical Handling/Availability
Improved CT over broader pH
range
Chemical Efficiency
More Skilled Operators Needed
Better Giardia/Crypto control
*Source: ClO2 Handbook
ICA technology overcomes the major disadvantages of
ClO2 Generation for small water systems
ICA TriNova, LLC
100
Drinking Water Disinfection:
10 minute ClO2 Exposure
% Kill
80
60
E-coli
Cholera
40
20
0
1
5
ClO2 Solution Conc. (ppm)
10
ICA TriNova, LLC
ClO2 for Industrial Water Treatment
Chlorine dioxide is used for disinfection and oxidation in
industrial, food, and point of use water applications
• Major Applications:
–
Cooling Towers
–
Rinses for raw ag. Products
–
Flume waters disinfection
–
Waste Water disinfection
–
Drip Irrigation
–
Hospital Water
–
Hotel Water
–
Industrial waste water for phenol, cyanide destruction
ICA TriNova, LLC
ClO2 Gas Treatments
• ClO2 solution is great but Gas has exciting new possibilities
• ClO2 gas has long been know as a sanitizer/disinfectant/sterilant but
has had limited use due to a lack of easy generation technology
• ClO2 gas forms a rapid equilibrium with water - brings ClO2 to the
problem
ICA technology = practical, simple and predictability = $$$
ICA TriNova, LLC
ClO2 Gas Treatments of Tomatoes
ICA TriNova, LLC
ClO2 Gas Treatment of Tomatoes for Soft Rot
100.0%
100.0%
88.0%
90.0%
80.0%
70.0%
60.0%
50.0%
40.0%
30.0%
24.0%
20.0%
10.0%
0.0%
0.0%
Chamber 1
Chamber 2
0.0%
0.75ppm ClO2(g)
Ch 2 in bag
100 ppm HOCl
Untreated
Control
ICA TriNova, LLC
ClO2 Gas Treatments of Raw Ag.
ICA TriNova, LLC
ClO2 Gas Sanitizing of Food Tanks
ICA TriNova, LLC
ClO2 Gas Treatment of 800, 1200 & 1600 Gallon Tanks
Conditions
Volume of Tank (L)
3030
800
1600
1000
1200
1000
1600
Average ClO2 conc. (mg/L)
0.26
0.53
0.22
0.26
0.17
0.26
4
4
1
4
4
4
Exposure time (h)
Blade spin rate (RPM)
37
37
N
N
N
Y
N
N
Leakage of ClO2 (Y/N?)
N
N
Y
N
N
N
72.8
37.0
78.2
67.1
73.6
64.5
100.0
82.0
100.0
75.5
100.0
83.5
Bacteria inoculum
6.5
6.3
7.1
6.3
6.5
6.3
Yeast inoculum
7.1
6.4
6.9
6.4
7.1
6.4
Top
<1.3
<1.3
4.3
<1.3
<1.3
<1.3
Btm
<1.3
<1.3
5.1
<1.3
<1.3
<1.3
Top
5.3
5.1
>5.4
3.2
5.7
3.2
Btm
1.9
5.5
>5.4
3.5
5.7
<1.3
Top
>5.2
>5.0
2.8
>5.0
>5.2
>5.0
Btm
>5.2
>5.0
2.0
>5.0
>5.2
>5.0
Top
1.8
1.3
<1.5
3.2
1.4
3.2
Btm
5.2
0.9
<1.5
2.9
1.4
>5.1
Relative humidity (%)
Ctrl
38
Fan used (Y/N?)
Temperature ( F)
Log( No. of
Survivors )
6060
Total ClO2 over time (mg)
0
Log reduction
4540
Lb4005
Ca30
Lb4005
Ca30
ICA TriNova, LLC
Powder - ClO2 Gas Release
Control
Treatment with ClO2
-releasing powder
Sterilization
determination
Long pile
carpet
Autoclaved
Spore Strip
A
C
E
Spore strips
ClO2-treated
spore strip
Short pile
carpet
B
D
F
Control
Fig 4. Exposure of carpet with Bacillus species endospores to ClO2 -releasing powder
Sections of carpet (232.3 cm2, duplicates) with both long (10 mm, A & C) and short pile (4 mm, B & D) were tested with
sterility strips with Bacillus subtilis and B. stearothermophilus (2x106 spores, each was cut into four equal lengths spores)
embedded on edge into the pile of the carpets. The controlled-release ClO2 powder was applied to both pre-moistened (10 ml
sterile, deionized water) and dry carpet sections both at 7.8 mg/cm2 or 38.8 mg/cm2. Spore strips were recovered from the carpet
after 2 h and 24 h and cultured in Tryptic Soy broth (TSB) fortified with 0.3% sodium thiosulfate, and were monitored visually for
growth in comparison with control strips in the same media. Bacillus spp. were recovered from only 2 of 8 strips from moistened
carpets and none from dry carpets after 24 h at the 38.8 mg/cm2 concentration.
ICA TriNova, LLC
ClO2 Gas Hospitality
ICA TriNova, LLC
Chlorine Dioxide for Medical/Biothreat
•Advantages:
- low concentration sterlilant (< 25 mg/L)
- exhaust gas easy to destroy
- low temperature (25-30C)
- rapid cycle
•Limitations:
- limited penetrability
- gas must be generated on site
- pre-humidification
- corrosive to some metals
ICA TriNova, LLC
Medical Sterilization
ICA TriNova, LLC
ClO2 ATEK Concept
• Simple, shelf-stable, first-line responder
kit containing ClO2 gas, solution and
powder generation materials
• Puts established best available chemical
in the field where there is a gap in
response capability
• Products put ClO2 close to problem statement = faster response,
greater efficacy, minimizes collateral damage, and garners more
control over personnel exposure issues
• Complements large scale generator approach
• Capitalizes on government investment in ICA TriNova Products
ICA TriNova, LLC
Equipment Decon
ICA TriNova, LLC
Why ICA Z-Series CO2 is Unique
• Dry powder to gas CO2 production
• Controlled generation of gas CO2 - extended
low level or rapid high level gas release
• Patented substrate and reaction chemistries-10
patents, 2 patents applications filed
• Uncomplicated, safe and reliable
ICA TriNova, LLC
0.35
0.3
0.25
0.2
0.15
P1
P1
P1
P2
P2
P2
0.1
0.05
2
Total CO , Liters (Ref. 25C) per gm P ingredient
Fig 2: Carbon dioxide release from sachets
containing ICA Z-materials
R1
R2
R3
R1
R2
R3
;
;
;
;
;
;
S1
S1
S1
S2
S2
S2
P = precursor ingredient
R = precursor/activator formulation
S = precursor size designation
0
-0.05
-20
;
;
;
;
;
;
0
20
40
60
Time, hr
80
100
120
ICA TriNova, LLC
CDC/Army/USDA Study Results
Stimulant 2
Stimulant 1
Ave % Attracted
Ave % Attracted
CO2
21
Blank
0
CO2 Sachet
96
Blank
0
Activator
51
Blank
0
CO2 Sachet
93
CO2
2
Activator
70
CO2
12
CO2 Sachet
54
Activator
34
CO2 Sachet
63
Activator & CO2
26
ICA TriNova, LLC
Mosquito Surveillance/Control
ICA TriNova, LLC
ICA CO2 in Food Preservation
• Patents cover critical aspects of CO2 generation
• Patents cover the combined generation of CO2 and
ClO2
• Technology is scalable - package applications to ship
board containers
• ICA technology provides more design flexibility
because of impregnation and chemistry choice
• ICA platform provides other benefits with respect to
humidification, antimicrobials and other atmospheric
gases
ICA TriNova, LLC
ICA Value
• Products for gas, solution and powder release of ClO2
• Products for gas release of CO2
• Applications know-how in critical markets
• Technology platform - Leveraged R&D and new
product concepts