Glutathione: effect of Sudarshan Kriya

2 5 0 2 0 0 1 5 0 1 0 0 5 0 0 4 5 0 4 0 0 3 5 0 p=highly significant (0.000002) 3 0 0 o m in p=0.618

4 5 m in p=0.095

6 5 m in C o n t r o ls P r a c t io n e r s

SOD activity: effect of Sudarshan Kriya Catalase activity : effect of Sudarshan Kriya

0 .5

0 2 .5

2 1 .5

p= 0.001

1 o m in p=0.555

4 5 m in p=0.491

6 5 m in C o n tr o ls Pr a c tio n e r s 1 6 1 4 1 2 1 0 8 6 4 2 0 p= 0.0001

o m in p=0.683

4 5 m in p=0.001

6 5 m in C o n tr o ls Pr a c tio n e r s

Sharma H, Sen S, Singh A, Bhardwaj NK, Kochupillai V and Singh N. Sudarshan Kriya practitioners exhibit better antioxidant status and lower blood lactate levels Biological Psychology 63: 281 - 291, 2003.

SK & P : Effect : Immune system

NK cells : 3 groups • Those practising SK and P x at least 2 years • Normal controls • Cancer patients in remission Cancer patients in remission • Controls Vs those practicing SK & P NK cells : baseline, after 3 and 6 months.

S.N. Das, Additional Prof., Biotechnology, AIIMS

NK cells : Results

F lo w c y to m e try : N K C e lls in P B

3 0 1 5 1 0 2 5 2 0 5 0 N o rm a l s u b je c ts A O L te a c h e rs c a n c e r a p tie n ts NK cells significantly higher in SKY teachers Vs normal & cancer patients (p<0.001)

Cancer patients in remission

Control Vs practitioners of SK & P Vs cancer pts in remission NK Cells in study & control arm 2 5 2 0 5 0 1 5 1 0 1 Day 0 p < 0.001

p < 0.05

2 3

S a m p lin g tim e (w e e k s )

Day 8 Week 12 4 Week 24 P < 0.05

S t u d y a r m C o n t r o l a r m

Increase in NK cells and antioxidant defence

• May protect or delay the onset of several diseases specifically age related diseases including cancer • May slow down cancer progression

SK & P : tobacco Cessation : 82 subjects

Day 6 : 53 / 82 = 65% Month 2 : 63 individuals FU 23 Tobacco free 23/82 = 28% Month 6 : 34 individuals FU 17 Tobacco free 17 /82 = 21%

Tobacco cessation through SK & P

• Cost effective • No side effects • Durable • Urge to smoke disappears • No effort or supervision required

Publication

Kochupillai V, Kumar P, Singh D et al.

Effect of rhythmic breathing (Sudarshan Kriya and Pranayam) on immune functions and tobacco addiction. Annals New York Acad of Sciences. 1-11: 2005

Cholesterol study: Bangalore Medical College

250 200 150 100 50 0

Effect of Sudarshan Kriya Practise on Serum Cholestrol

Normal 7 day SK 45 day SK

Total Cholesterol decreased Effect of Sudarshan Kriya Practise on Serum LDL Cholesterol

180 160 140 120 100 80 60 40 20 0 118.32

91.75

74.72

Normal 7 day SK 45 day SK

Effect of Sudarshan Kriya Practise on Serum HDL Cholesterol

70 60 50 40 30 20 10 0 43.17

46.55

51.51

Normal 7 day SK 45 day SK

LDL decreased (Bad Cholesterol) HDL increased (Good Cholesterol)

Dr. Geetha

Tata Institute of Social Sciences: Research

• Participants: Management level • Ambit corporate finance, Bacardi, Cadbury’s, Indian oil, Mukand Steel, NTCP, Rallis India, Strategic capital securities, Tata chemicals, World bank groups, WHO Transasia Biochemicals • Total participants: 543 underwent AOL workshop and learnt SK & P

Tata Institute Social Science: Research (Contd)

Improved state of mind = 88% Improvement in dealing with people = Handled stressful situation better = Practicing SK & P: Regularly Recommended AOL course to others = = 60% 58% 58% 60%

Health & Spirituality

• SK & P and meditation (spiritual practices): –

elimination of stress, anxiety

–

allow free flow of neuropeptides and receptors: molecules of emotions

• Better Immune status and antioxidant defense • Freedom from addiction (tobacco & alcohol) • Healthier body and healthier mind

World Conference :

Expanding Paradigms: Science, Consciousness and Spirituality February 24

th

& 25

th

2006

Summary : Research Presentations

SKY : Wellness effect

•

109 subjects 56 SKY vs 53 control (relaxed x 15 min) After 6 weeks of practice

• • •

SKY gr Lower anxiety, depression and stress Higher degree of optimism Perceived the practices as a positive event Strong relaxation response – stress reduction Dr. Fahlri, Prof. Molecular and Cell Biology, Univ. of Oslo, Norway

SK : Effect on gene expression

• • • • •

SK affects stress related signaling/ metabolic pathways 3 fold higher levels of glutathione in SKY practitioners Also higher levels of Catalase, glutathione N transferase and glutathione peroxidase in RNA in SKY practitioners as observed by RT – PCR. Increase in HTERT in SK practitioners : indicates delayed senescence – longer life span Decrease in beta 2, C Myc and C-fos – Suggests better protection against cancer Dr. Neeta Singh, AIIMS

SKY : Heart rate variability

•

Improved heart rate variability within 6 days of practice of SK and P Dr. Narendra Bhardwaj & Dr. KK Deepak, Prof. Physiology, AIIMS

Post Traumatic stress disorder

•

Combination of Asanas, Pranayam, meditation, yoga nidra, Chanting, Reflection on yoga philosophy etc. highly efficient, cheap, safe and self administrable processes

•

Multi component yoga intervention (MCY1) most – effective Dr. Janis Carter Psychiatrist, Brisbane, Australia

Breath, water and sound (BWS) program : PTSD

•

BWS program offered to tsunami victims

–

80 subjects each

•

BWS program

•

BWS & Traumatic Incidence Reduction

•

controls

•

BWS group significantly reduced scores for PTSD and depression – Addition of TIR showed no further Teresa Descilo, Trauma Specialist, Executive Director Victim Service Center, Miami, FL benefits

Wendell Taylor, Lata More, PhD.

Janis Apted, MLS

SKY : effect on

•

clinicians

American oncologists: burnout feeling : 56 %

• • •

Dealing with dying patients, Breaking bad news to very sick End of life issues

•

MD Anderson Cancer Center - AOL program

–

Faculty

• • •

Favorable effects Greater sense of well being Release of tension and anxiety

Univ. of Texas, Health Science Center, Houston •

Feeling of more control over their work

Were there any changes in the following? Worse Anxiety/ Tension Ability to Stay Calm Mood Ability to Focus Relationships Outside Work Feelings of Stress Sleep Anger/ Frustration Closeness w/ Coworkers Optimism 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% No Change 4 % 4% 12 % 12 % 21 % Slightly Better 25 % 25 % 12 % 38 % 38 % Better 38 % 42 % 50 % 46 % 29 % 4 % 25 % 17 % 38 % 12 % 21 % 25 % 25 % 33 % 33 % 38 % 33 % 42 % 21 % 29 % Much Better 33 % 29 % 25 % 4 % 12 % 38 % 17 % 17 % 8 % 25 %

SKY : Effect on occupational stress and anxiety : Executive and others

Sixty software workers vs. controls • Significant reduction: anxiety score • Improvement in stress coping skills Dr. Vedamurthachar NIMHANS, Bangalore, India

SKY : Breast Cancer

• •

Two independent studies

– –

Arielle Warner – Palo Alto,CA Manju Sengar : AIIMS, Delhi Significant improvement (p< 0.0001)

– – – – – – –

Quality of life Spiritual well being Positive state of mind Perceived stress Decreased stress symptoms Increase in NK cells Side effect of chemotherapy reduced

Perfect Health

Body without disease Breath without quiver Mind without stress Intellect without obsession Memory without trauma Ego which can accept all self without sorrow

H H Sri Sri Ravi Shankar

Sri Sri Global Meditating Doctor’s Association

(Sri Sri GMDA)

Forms available Life membership Rs. 500/-