Transcript No Slide Title

DF-200: Sandia Decontamination Formulation
for Neutralization of CBW Agents and Toxic
Industrial Chemicals
Mark D. Tucker
(505)844-7264
[email protected]
Sandia National Laboratories
Presentation Outline
• Background
• Performance Characteristics of DF-200
– Decontamination of Chemical Warfare
Agents
– Decontamination of Toxic Industrial
Chemicals
– Decontamination of Biological Warfare
Agents and Pathogens
• Commercialization
• Other Decontamination Activities
• Summary
Response to a Domestic CBW Incident
Event Timeline
Fate and
Transport
Modeling
CBW
Event
Detection
Mitigation
First
Response
Facility
Restoration
Risk
Assessment
Decontamination / Restoration
Event Timeline
Re-Occupy
Facility
Sandia Decon Foam
Development Overview
The Problem
Our Response
Historical decon formulations for
Sandia has developed an aqueous
CBW agents are highly toxic
formulation with low toxicity and
and/or highly corrosive
corrosivity properties for the rapid
destruction of CBW agents
The Challenges
The Objective
Rapid Deployment
To develop a rapid, effective, and safe
decontamination technology for the
restoration of civilian facilities in the event of a
domestic terrorist attack
Rapid Destruction of CBW Agents
Common Formulation for all CBW Agents
Low toxicity and corrosivity
Corrosion Comparisons
Steel Coupons
Deionized Water 24 Hour Exposure
Sandia Decon Foam 24 Hour Exposure
Bleach - 24 Hour
Exposure
DF-200 Formulation
Characteristics
• Rapid response
– quick to deploy
– quick to react
• Low logistics support and water demand
and minimal run-off of fluids
• Minimal health and collateral damage
– low toxicity and corrosivity properties
• Applicable in a variety of scenarios
– work has mostly focused on deployment as a foam
– formulation can also be deployed as a spray, fog, mist, or cream
• Successful results in a number of laboratory and field tests
– RestOps, JSFDS, Dugway Spore Kill Tests
• Successfully used in actual remediation of anthrax contaminated
buildings
Sandia Decon Formulation
Deployment
Presentation Outline
• Background
• Performance Characteristics of DF-200
– Decontamination of Chemical Warfare
Agents
– Decontamination of Toxic Industrial
Chemicals
– Decontamination of Biological Warfare
Agents and Pathogens
• Commercialization
• Other Decontamination Activities
• Summary
DF-200 Performance
Neutralization of CW Agents
Decon of CW Agents at Various Contact Times
mg Unreacted Agent
25
20
0 Minutes
15
! Minute
10
15 Minutes
5
60 Minutes
0
GD
VX
HD
CW Agent
Complete destruction of GD within 1 minute
Complete destruction of VX within 10 minutes
Complete destruction of HD within 30 minutes
DF-200 Performance
Results against TICs
% Decontamination
TIC
1 Minute
15 Minutes
60 Minutes
Malathion (liquid)
89
95
Below Detection
Hydrogen Cyanide (gas)
>99
>99
>99
Sodium Cyanide (solid)
93
98
>99
Butyl Isocyanate (liquid)
99
Below Detection
Below Detection
Carbon Disulfide (liquid)
>99
>99
Below Detection
Phosgene (gas)
98
>99
>99
Solution Testing: Malathion, Sodium Cyanide, Butyl Isocyanate, Carbon Disulfide
Headspace Testing: Hydrogen Cyanide, Phosgene
DF-200 Performance
Kill of BW Agents in DF-200
B. anthracis AMES-RIID
Control
15 min contact time
30 min contact time
60 min contact time
Average CFU/ml
1.21E+07
NG
NG
NG
Log Reduction
0
7
7
7
% Reduction
0.00
100.00004
100.00004
100.00004
Kill of anthrax spores by DF-200
Y. Pestis (ATCC 11953)
Control
15 min contact time
30 min contact time
60 min contact time
Average CFU/ml
1.33E+07
NG
NG
NG
Log Reduction
0
7
7
7
Kill of the plague bacterium by DF-200
% Reduction
0.00
100.00004
100.00004
100.00004
Kill of Anthrax Simulant
Scanning Electron Microscopy
As received
DF-100
Contact Time: 1 Hour
Destruction of bacterial spores in
DF-100
B. globigii Spore Kill - Room Test
DF-100 Performance at Dugway Field Tests
Test Parameters
•
•
•
•
8’ x 8’ x 8’ office
Bacillus globigii spores
contaminated with a simulated explosion
spores ‘weathered’ for 24 hours and then
sampled
• room temperature = 41°F
• Sandia formulation deployed as a foam
– Intelagard backpack device
– approximately 17liters applied (0.4 L/m2)
• sampling occurred 24 hours after decon
B. globigii Spore Kill - Room Test
Results of Dugway Field Tests using DF-100
SURFACE
CONTAMINATED
(Surface average in CFU/SQ. IN.)
DECONTAMINATED
(Surface average in CFU/SQ. IN.)
Floor (painted concrete)
7.67E+07
0.00E+00
Floor (tile)
1.31E+07
0.00E+00
Floor (carpet)
1.23E+07
0.00E+00
Floor (wood)
7.30E+06
0.00E+00
Window (glass)
5.32E+04
0.00E+00
Painted wall below window
8.16E+04
0.00E+00
Left hand wall panels
4.70E+04
0.00E+00
Wall (stucco)
2.80E+05
0.00E+00
Painted wall above carpet
4.56E+04
0.00E+00
Carpeted wall
1.08E+06
0.00E+00
Door
3.13E+04
0.00E+00
Ceiling
8.49E+02
0.00E+00
Summary of Anthrax Incidents
Sandia Foam Use (DF-100)
• Capitol Hill Office Buildings
– Sandia formulation (foam) successfully
used in selected areas of Hart, Ford, and
Dirksen office buildings
• ABC Building (New York)
– Sandia formulation (fog) successfully used
• New York Post Building
– Sandia formulation (fog) successfully used
• AMI Building (Florida)
– Sandia formulation (liquid bath)
successfully used to decontaminate
electronic media
DF-200 Performance
Summary of Decon Effectiveness
Agent
Contact Time
(Minutes)
Byproducts
Nerve Agents (G)
1-10
Hydrolysis
Nerve Agents (V)
10-15
Breakage of P-S Bond
Vesicants (HD)
30
Oxidation
Anthrax Spores
15-30
Killed Organisms
Vegetative Bacteria,
Viruses
1-15
Killed Organisms
Application Rate: 0.5 L of DF-200 Liquid per square meter of contaminated surface
Challenge Level (CW): 10 g of agent per square meter
Challenge Level (BW): 107 organisms per square centimeter
Presentation Outline
• Background
• Performance Characteristics of DF-200
– Decontamination of Chemical Warfare
Agents
– Decontamination of Toxic Industrial
Chemicals
– Decontamination of Biological Warfare
Agents and Pathogens
• Commercialization
• Other Decontamination Activities
• Summary
Commercial Partners
EnviroFoam Technologies, Inc.
2903 Wall Triana Hwy
Huntsville, Alabama 35824
Modec, Inc.
4725 Oakland Street
Denver, Colorado 80239
Toll-free: (800) 542-4665
Phone: (256) 319-0137
Fax: (256) 461-8136
Toll-free: (800) 967-7887
Phone: (303) 373-2696
Fax: (303) 373-2699
DF-200: Foam Deployment
Intelagard CAF
Backpack
The foam can be
deployed through a
variety of delivery
systems - both largescale and small-scale
Hand-held Aspirating
Air Foam Generator
Envirofoam
EasyCAFsTM System
EPA Registration
DF-200 Status
• As a result of the October 2001 anthrax
incidents, the EPA is now clearly identified
as the lead agency for remediation
• The EPA has determined that all products
used for anthrax remediation must be
registered as sterilants
• Sterilant registration requires completion of AOAC sporicidal
tests against Bacillus and Clostridium spores on two different
carriers (porcelain cylinder and suture loop)
• Both Envirofoam Technologies and Modec have submitted their
products to EPA-approved laboratories for testing
• One company has passed the sporicidal tests while the other
company’s tests are still in progress
Sandia Decon Formulation (DF-200)
Military Use
The US Military has recently
purchased relatively large
quantities of DF-200 for
possible use in the War
Against Terrorism
Presentation Outline
• Background
• Performance Characteristics of DF-200
– Decontamination of Chemical Warfare
Agents
– Decontamination of Toxic Industrial
Chemicals
– Decontamination of Biological Warfare
Agents and Pathogens
• Commercialization
• Other Decontamination Activities
• Summary
Other Decontamination Work
Expanded Uses for the DF-200 Technology
Personnel Decon
DF-200 Formulation
(Fog / Mist / Spray Applications)
(With Licensees)
DF-200
CBW/TIC Decontamination
Restoration DDAP
(With LLNL)
Containment / Mitigation
Presentation Outline
• Background
• Performance Characteristics of DF-200
– Decontamination of Chemical Warfare
Agents
– Decontamination of Toxic Industrial
Chemicals
– Decontamination of Biological Warfare
Agents and Pathogens
• Commercialization
• Other Decontamination Activities
• Summary
DF-200 Technology
Summary
•
•
•
•
DF-100 was successfully used in response
to October 2001 anthrax incidents
DF-200 has been recently purchased by the
U.S. Military under an urgent need order for
possible use in the War Against Terrorism
DF-200 is applicable for response to
CBW/TIC attacks in domestic scenarios
Many opportunities exist to utilize the
fundamental DF-200 chemistry for new
applications
Contact Information
Mark D. Tucker
505-844-7264
[email protected]
DF-200 Foam Demonstration for
President George W. Bush; July 22, 2002