Transcript Synthesis of 5,10,15,20-tetraphenylporphyrin The

Developing a synthetic molecule imitating the
properties of hemoglobin to reduce carbon
monoxide emission from automobile exhaust
Project Code: HR 205
HANS RAJ COLLEGE
College E-mail: [email protected]
Principal E-mail: [email protected]
Name of Project Investigators with Designation,
Department, Email ID and Mobile number
Dr. Dinesh Kumar Gautam
Assistant Professor (Zoology)
Email: [email protected]
Mob: 9818427794
Mr. Satish Chand
Assistant Professor (Chemistry)
Email: [email protected]
Mob: 9968136659
Dr. Ambika
Assistant Professor (Chemistry)
Email: [email protected]
Mob: 9911385535, 9968643901
Mentor: Dr. J.P. Subrahmanyam
Senior Professor (Department of Mech. Eng.)
I.T.M. University, HUDA, Sector 23A,
Gurgaon, Haryana 122017
Mob: 9818263487
Names of the Students, Course, Department,
Email ID and Mobile number in the Project
Name of Student
BSc (H) Course
E-Mail
Mobile No.
Niyati Piplani
Zoology II Sem.
[email protected]
9990470045
Shubham Mukherjee
Zoology II Sem.
[email protected]
9013232933
Sonal Gupta
Zoology II Sem.
[email protected]
9958804681
Rajnish Rai
Zoology II Sem.
[email protected]
9015310174
Nidhi Kaushik
Chemistry I Sem.
[email protected]
8376846095
Ritika Verma
Chemistry I Sem.
[email protected]
9582977667
Simranjeet Kaur
Chemistry I Sem.
[email protected]
8527829813
Manika Mittal
Chemistry I Sem.
[email protected]
9717329142
Rishabh kumar
Chemistry II Sem.
[email protected]
9868496926
Kritika Nagpal
Chemistry II Sem.
[email protected]
9582627789
Methodology involving the synthesis of tetra phenyl
porphyrin , its binding with carbon monoxide and the
expected out come
X
N
H
Y
propionic acid/reflux
+
CHO
X
BF3 etherate/DDQ
Y
X
NH N
N HN
X
Y
Y
Y
X
(a) X=Y=H, TPPH2
(b) X=Y=Cl, Cl8TPPH2
(a) X=Y=H
(b) X=Y=Cl
FeCl2.4H2O/DMF
X
Y
X
Y
N Cl N
Fe(III)
N N
Y
X
CO
X
Y
X
CO
Y
X
Y
N Cl N
Fe(III)
N N
Y
X
Y
X
(a) X=Y=H, TPPFe(III)Cl
(b) X=Y=Cl, Cl8TPPFe(III)Cl
The cyclocondensation of equimolar amount of pyrrole with aromatic aldehydes in
refluxing propionic acid to get the required 5,10,15,20-tetra aryl porphyrins (TAP).
Structural analysis and binding studies of TAP Fe(III)Cl with CO will be confirmed
by IR, UV and other spectroscopic data.