Transcript placenta

What’s happening here?
fission
LECTURE PRESENTATIONS
For CAMPBELL BIOLOGY, NINTH EDITION
Jane B. Reece, Lisa A. Urry, Michael L. Cain, Steven A. Wasserman, Peter V. Minorsky, Robert B. Jackson
Chapter 46
Animal Reproduction
Lectures by
Erin Barley
Kathleen Fitzpatrick
© 2011 Pearson Education, Inc.
How can each of these slugs be both male and female?
Create a graphic organizer including
sexual vs. asexual reproduction
• Word bank: binary fission, budding,
fragmentation, parthenogensis, external
fertilization, internal fertilization
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Video: Hydra Budding
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Asexual reproduction
Pros
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Cons
Sexual reproduction
Pros
Cons
Sexual con: half the number of daughters per mom
Sexual reproduction
Asexual reproduction
Female
Generation 1
Female
Figure 46.3-2
Sexual reproduction
Asexual reproduction
Female
Generation 1
Female
Generation 2
Male
Figure 46.3-3
Sexual reproduction
Asexual reproduction
Female
Generation 1
Female
Generation 2
Male
Generation 3
Reproductive handicap of sex
Sexual reproduction
Asexual reproduction
Female
Generation 1
Female
Generation 2
Male
Generation 3
Generation 4
Ovulation, courtship, and reproduction are coordinated with resources, but resources can be disrupted.
Ovary
size
(a) A. uniparens females
Ovulation
Hormone
level
Estradiol
Ovulation
Progesterone
Time
Behavior
Asexual whiptail
lizards are
descended from
a sexual species,
and females still
exhibit male
mating behaviors
Female
Male- Female
like
(b) The sexual behavior of A. uniparens is
correlated with the cycle of ovulation.
Malelike
parthenogenesis in aphids
Gender change in fish
Animal homosexuality
Video: Hydra Releasing Sperm
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Initiated external fertilization.
External fertilization
Pros
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Cons
Internal fertilization
Pros
Cons
Parental care:
Surinam toad
mom
mouthbrooding
cichlids
At what are we looking?
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• A cloaca of a redtailed hawk
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Gender-specific reproductive anatomy
Accessory
gland
Ejaculatory
duct
Penis and
claspers
(a) Male fruit fly
Ovary
Testis
Oviduct
Spermatheca
Vas
deferens
Seminal
vesicle
Accessory
gland
(b) Female fruit fly
Uterus
Vulva
Animation: Female Reproductive Anatomy
Right-click slide / select “Play”
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Figure 46.10
Oviduct
Ovary
Uterus
(Urinary bladder)
(Pubic bone)
(Rectum)
Cervix
Vagina
Urethra
Body
Clitoris
Glans
Prepuce
Labia minora
Labia majora
Major vestibular
(Bartholin’s) gland
Vaginal opening
Ovaries
Oviduct
Follicles
Corpus luteum
Uterus
Uterine wall
Endometrium
Cervix
Vagina
Mammary Glands
• The mammary glands are not part of the
reproductive system but are important to
mammalian reproduction
– Within the glands, small sacs of epithelial tissue secrete
milk
– animation
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Male Reproductive Anatomy
• The male’s external reproductive organs are the
scrotum and penis
• Internal organs are the gonads, which produce
sperm and hormones, and accessory glands
• Most mammals have a baculum (penile bone)
– Raccoon’s baculum 
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Animation: Male Reproductive Anatomy
Right-click slide / select “Play”
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Figure 46.11
Seminal
vesicle
(behind
bladder)
(Urinary bladder)
Prostate gland
Bulbourethral gland
Urethra
Scrotum
Erectile tissue of penis
Vas deferens
Epididymis
Testis
(Urinary bladder)
Seminal vesicle
(Urinary duct)
(Rectum)
Vas deferens
(Pubic bone)
Ejaculatory duct
Prostate gland
Bulbourethral gland
Erectile
tissue
Urethra
Vas deferens
Epididymis
Testis
Scrotum
Glans
Prepuce
Penis
Accessory Glands
• Semen is composed of sperm plus secretions
from three sets of accessory glands
• The two seminal vesicles contribute about 60%
of the total volume of semen
• The prostate gland secretes its products directly
into the urethra through several small ducts
• The bulbourethral glands secrete a clear mucus
before ejaculation that neutralizes acidic urine
remaining in the urethra
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Gametogenesis
• Spermatogenesis, the development of sperm, is
continuous and prolific (millions of sperm are
produced per day; each sperm takes about 7
weeks to develop
• Oogenesis, the development of a mature egg, is a
prolonged process
• Immature eggs form in the female embryo but do
not complete their development until years or
decades later
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•
Spermatogenesis differs from oogenesis in three
ways
1. All four products of meiosis develop into sperm
while only one of the four becomes an egg
2. Spermatogenesis occurs throughout
adolescence and adulthood
3. Sperm are produced continuously without the
prolonged interruptions in oogenesis
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Figure 46.12aa
Epididymis Seminiferous
Sertoli cell
tubule
nucleus
Spermatogonium
Primary
spermatocyte
Testis
Cross section of
seminiferous tubule
Secondary
spermatocyte
Spermatids
(two stages)
Lumen of
seminiferous tubule
Sperm cell
Figure 46.12ab
Primordial germ cell in embryo
Mitotic divisions
2n
Spermatogonial stem cell
Mitotic divisions
Spermatogonium
2n
Mitotic divisions
Primary spermatocyte
2n
Meiosis I
Secondary spermatocyte
n
n
Meiosis II
Early
spermatid
Sperm cell
n
n
n
n
Differentiation
(Sertoli cells
provide nutrients)
n
n
n
n
Figure 46.12ac
Neck
Plasma
membrane
Tail
Midpiece Head
Acrosome
Nucleus
Mitochondria
Figure 46.12b
Primary
oocyte
within
follicle
Ovary
Primordial germ cell
Growing
follicle
In embryo
Mitotic divisions
2n
Oogonium
Mitotic divisions
Primary oocyte
(present at birth), arrested
in prophase of meiosis I
2n
First
polar
body
Completion of meiosis I
and onset of meiosis II
n
n
Secondary oocyte,
arrested at metaphase of
meiosis II
Ovulation, sperm entry
Mature follicle
Ruptured
follicle
Ovulated
secondary
oocyte
Completion of meiosis II
Corpus luteum
Second
polar
n
body
n
Fertilized egg
Degenerating
corpus luteum
Concept 46.4: The interplay of tropic and
sex hormones regulates mammalian
reproduction
• Human reproduction is coordinated by hormones
from the hypothalamus, anterior pituitary, and
gonads
• Gonadotropin-releasing hormone (GnRH) is
secreted by the hypothalamus and directs the
release of FSH and LH from the anterior pituitary
• FSH and LH regulate processes in the gonads and
the production of sex hormones
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Hormonal Control of the Female
Reproductive Cycles
• In females, the secretion of hormones and the
reproductive events they regulate are cyclic
• Prior to ovulation, the endometrium thickens with
blood vessels in preparation for embryo
implantation
• If an embryo does not implant in the endometrium,
the endometrium is shed in a process called
menstruation
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• Hormones closely link the two cycles of female
reproduction
– Changes in the uterus define the menstrual cycle
(also called the uterine cycle)
– Changes in the ovaries define the ovarian cycle
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(a)
Control by hypothalamus
GnRH
1
Anterior pituitary
2
(b)
Inhibited by combination of
estradiol and progesterone

Hypothalamus
FSH

Stimulated by high levels
of estradiol

Inhibited by low levels of
estradiol
LH
Pituitary gonadotropins
in blood
6
LH
FSH
(c)
Ovarian cycle
7
Growing follicle
Maturing
follicle
8
Follicular phase
Corpus
luteum
Ovulation
Ovarian hormones
in blood
Degenerating
corpus luteum
Luteal phase
Estradiol secreted
by growing follicle in
increasing amounts
4
(d)
LH surge triggers
ovulation
FSH and LH stimulate
follicle to grow
3
Progesterone and
estradiol secreted
by corpus luteum
Peak causes
LH surge
(see 6 )
5
10
9
Estradiol
Progesterone
Progesterone and estradiol promote thickening
of endometrium
Estradiol level
very low
Uterine (menstrual) cycle
(e)
Endometrium
Menstrual flow phase Proliferative phase
Days
Figure 46.13
0
5
10
14 15
Secretory phase
20
25
28
The Ovarian Cycle
• The sequential release of GnRH then FSH and LH
stimulates follicle growth
• Follicle growth and an increase in the hormone
estradiol characterize the follicular phase of the
ovarian cycle
• The follicular phase ends at ovulation, and the
secondary oocyte is released
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Animation: Ovulation
Right-click slide / select “Play”
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Animation: Post Ovulation
Right-click slide / select “Play”
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The Uterine (Menstrual) Cycle
• Hormones coordinate the uterine cycle with the
ovarian cycle
– Thickening of the endometrium during the
proliferative phase coordinates with the follicular
phase
– Secretion of nutrients during the secretory phase
coordinates with the luteal phase
– Shedding of the endometrium during the
menstrual flow phase coordinates with the
growth of new ovarian follicles
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Menstrual Versus Estrous Cycles
• Menstrual cycles are characteristic only of humans
and some other primates
– The endometrium is shed from the uterus in a
bleeding called menstruation
– Sexual receptivity is not limited to a time frame
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Hormonal Control of the Male Reproductive
System
• FSH promotes the activity of Sertoli cells, which
nourish developing sperm
• LH regulates Leydig cells, which secrete
testosterone and other androgens, which in turn
promote spermatogenesis
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Animation: Male Hormones
Right-click slide / select “Play”
© 2011 Pearson Education, Inc.
Figure 46.14

Hypothalamus
GnRH


FSH
LH
Leydig cells
Sertoli cells
Inhibin
Spermatogenesis
Testis
Testosterone
Negative feedback
Negative feedback
Anterior pituitary
• Testosterone regulates the production of GnRH,
FSH, and LH through negative feedback
mechanisms
• Sertoli cells secrete the hormone inhibin, which
reduces FSH secretion from the anterior pituitary
© 2011 Pearson Education, Inc.
Human Sexual Response
• Two reactions predominate in both sexes
– Vasocongestion, the filling of tissue with blood
– Myotonia, increased muscle tension
• The sexual response cycle has four phases:
excitement, plateau, orgasm, and resolution
• Excitement prepares the penis and vagina for
coitus (sexual intercourse)
© 2011 Pearson Education, Inc.
Formation of the zygote and early postfertilization events.
3
Cleavage
4
Cleavage
continues
5
Implantation
Ovary
2
Fertilization
Uterus
1
Ovulation
(a) From ovulation to implantation
Endometrium
Endometrium
Inner cell
mass
Cavity
Blastocyst
(b) Implantation of blastocyst
Trophoblast
• During its first 2 to 4 weeks, the embryo obtains
nutrients directly from the endometrium
• Meanwhile, the outer layer of the blastocyst, called
the trophoblast, mingles with the endometrium
and eventually forms the placenta
• Blood from the embryo travels to the placenta
through arteries of the umbilical cord and returns
via the umbilical vein
© 2011 Pearson Education, Inc.
Figure 46.16
Maternal
arteries
Placenta
Umbilical
cord
Maternal
veins
Maternal
portion of
placenta
Chorionic
villus,
containing
fetal
capillaries
Fetal
portion of
placenta
(chorion)
Maternal
blood pool
Uterus
Fetal arteriole
Fetal venule
Umbilical cord
Umbilical
arteries
Umbilical vein
• The first trimester is the main period of
organogenesis, development of the body organs
• All the major structures are present by 8 weeks,
and the embryo is called a fetus
© 2011 Pearson Education, Inc.
Figure 46.17a
(a) 5 weeks
Figure 46.17b
(b) 14 weeks
Figure 46.17c
(c) 20 weeks
Figure 46.18
from
ovaries
Oxytocin

from fetus
and mother’s
posterior pituitary
Activates oxytocin
receptors on uterus
Stimulates uterus
to contract
Stimulates
placenta to make
Prostaglandins
Stimulate more
contractions
of uterus

Positive feedback
Estradiol
LABOR, STAGE 1
Placenta
Umbilical cord
Uterus
Cervix
1 Dilation of the cervix
Figure 46.19b
2 Expulsion: delivery of the infant
Figure 46.19c
Uterus
Placenta
(detaching)
Umbilical
cord
3 Delivery of the placenta
Yayyyyyyyy!
Figure 46.20
Female
Male
Method
Event
Production
of sperm
Event
Production of
primary oocytes
Vasectomy
Oocyte
Sperm transport
development
down male
and ovulation
duct system
Abstinence
Condom
Coitus
interruptus
(very high
failure rate)
Method
Combination
birth control
pill (or injection,
patch, or
vaginal ring)
Abstinence
Female condom
Sperm
deposited
in vagina
Capture of the
oocyte by the
oviduct
Tubal ligation
Sperm
movement
through female
reproductive
tract
Transport
of oocyte in
oviduct
Spermicides;
diaphragm;
progestin alone
(as minipill
or injection)
Meeting of sperm and oocyte
in oviduct
Union of sperm and egg
Implantation of blastocyst
in endometrium
Morning-after
pill; intrauterine
device (IUD)
Treating Infertility
• Modern technology can provide infertile couples
with assisted reproductive technologies
• In vitro fertilization (IVF) mixes eggs with sperm
in culture dishes and returns the embryo to the
uterus at the 8-cell stage video
• Sperm are injected directly into an egg in a type of
IVF called intracytoplasmic sperm injection
(ICSI)
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Video: Ultrasound of Human Fetus 1
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Video: Ultrasound of Human Fetus 2
© 2011 Pearson Education, Inc.
SUMMARY FIGURE
Human gametogenesis
Oogenesis
Spermatogenesis
Primary
spermatocyte
2n
2n
Primary
oocyte
n
n
Secondary
spermatocytes
n
n
n
n
n
Spermatids
n
n
n
n
Sperm
n
n
n
Polar body
Secondary
oocyte
Polar body
Fertilized egg
Figure 46.UN02
Reproduction Questions (answer in outline
form using books, after you have watched a
video or two presented by Meaghan)
1. Explain the differences between sexual
and asexual reproduction.
2. Create a table of the role of the parts of
the male and female reproductive
anatomy
3. Explain how hormones regulate the
female reproductive cycle.
4. Same thing, but for boys
5. Create a flow chart of the course of
conception to birth.